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| 1 | Outcome of 1355 consecutive transabdominal chorionic villus samplings in 1351 patients显示文摘Background The true risk of choronic villus sampling (C VS) is poorly defined. The objective of this study was to review the clinical o utcome of transabdominal CVS performed in a university teaching unit, with an em phasis on the complication rate. Methods A comprehensive audit database was maintained for 1351 pregnant women, including 17 sets of twin pregnancies, who had a CVS. Details a nd outcome of all CVSs made in the unit between May 1996 and May 2004 were revie wed. All CVSs were performed by one of 5 operators using the identical techniqu es. Results All procedures were performed transabdominally. A tota l of 1355 CVSs were performed because there were 4 dichorionic twin pregnancies which required 2 punctures. The mean gestation at CVS was (11.8±0.7) weeks, and 97.3% of the procedures were performed between 11 and 13 completed weeks. The majority (96.2%) required only 1 puncture to achieve correct needle placeme nt. The procedure failed to obtain an adequate sample in 4 subjects (0.30%). A total of 1351 chromosomal studies were requested and there was 1 case (0.07%) of culture failure. The results of chromosomal studies were available within 1 4 days in 36.7% of the cases and within 21 days in 94.0%. Overall, 77 chromos omal abnormalities (5.7%) and 5 cases of thalassemia major were detected. Preg nancy outcome was unknown in only 13 singleton subjects (0.96%). In the remain ing 1355 fetuses, there were 76 pregnancy terminations (5.56%), 10 fetal losses with obvious obstetric causes (0.73%), and 21 potentially procedure-relat ed fetal losses (1.54%). In the last group, the majority had one or more co-e xisting obstetric complications. The background fetal loss rate for pregnancies at similar gestational age in the unit was about 0.8%. Therefore, the procedu re-related fetal loss rate was estimated to be at the maximum of 0.74%. Conclusions In experienced hands, first trimester transabdomina l CVS is an accurate and safe invasive prenatal diagnostic procedure. It should be one of the treatment options available to pregnant women who require prenata l genetic diagnosis. | LAU Tze Kin LEUNG Tak Yeung FUNG Tak Yuen Daljit S SAHOTA LEUNG Tse Ngong | 2005 | Chinese Medical Journal2005，，20： | 8 |
| 2 | Synthesis of a New Chiral N,N,N-Tridentate Pyridinebisimidazoline Ligand Library and Its Application in Ru-Catalyzed Asymmetric Epoxidation显示文摘 | Anilkumar G Tse M K | 2005 | Org Lett2005，7，16： | 1 |
| 3 | The role of charge-transfer integral in determining and engineering the carrier mobilities of 9,10-di( 2- naphthyl) anthracene compounds显示文摘 | Tse S C So S K Yeung M Y | 2006 | Chem Phys Lett2006，422，： | 1 |
| 4 | Reduction of Power Converter EMI Emission Using Soft-Switching Technique显示文摘 | Chung H Hui S Y R Tse K K | 1998 | IEEE Transaction on Electromagnetic Compatibility1998，40，3： | 1 |
| 5 | Formation and Decomposition Mecha- nisms for Clathrate Hydrates 显示文摘 | Tse J S Klug D D | 2002 | J Supramolecular Chem2002，2，45： | 1 |
| 6 | Higher median levels of free hCG and PAPP-A in a Chinese ethnic group显示文摘 | Tak Y L Kevin S Tse N L | 2006 | Fetal Diagn Ther2006，21，1： | 1 |
| 7 | Role of Permanent Pacing to Prevent Atrial Fibrillation: Science Advisory From the American Heart Association Council on Clinical Cardiology (Subcommittee on Electrocardiography and Arrhythmias) and the Quality of Care and Outcomes Research Interdisciplin显示文摘 | Bradley P. Knight Bernard J. Gersh Mark D. Carlson Paul A. Friedman Robert L. McNamara S Adam Strickberger Hung Fat Tse Albert L. Waldo | 2005 | Circulation2005，，2： | 1 |
| 8 | Spherical simplex-radial cubature Kalman filter 显示文摘 | Wang S Y Feng J C Tse C K | 2014 | IEEE Signal Processing Letters2014，21，1： | 1 |
| 9 | Accelerated life test samplingplans for the Weibull distribution under Type I progressive inter-val censoring with random removals 显示文摘 | Ding C Yang C Y Tse S K | 2010 | Journal of StatisticalComputation and Simulation2010，80，8： | 1 |
| 10 | Multi-cell downlink capacity with coordinated processing 显示文摘 | JING S TSE D N C HOU J | 2008 | EURASIP Journal on Wireless Communications and Networking2008，，8： | 1 |
| 11 | Mergers and investments in cost reduction with private information revisted 显示文摘 | Tse M K S | 1997 | International Journal of Industrial Organization1997，15，： | 1 |
| 12 | A fixed-frequency pulsewidth modulation based quasi-sliding-mode controller for Buck converters显示文摘 | TAN S C LAI Y M TSE C K | 2005 | IEEE Transactions on Power Electronics2005，20，6： | 1 |
| 13 | Analysis and Spectral characteristics of a spread-spectrum technique for conducted EMI suppression显示文摘 | Tse K K Chung H Hui S Y R So H C | 2000 | IEEE Trans on Power Electronics2000，15，： | 1 |
| 14 | Economic perspectives of aerodynamic treatments of square tall buildings显示文摘 | Tse K T Hitchcock P A Kwok K C S | 2009 | Journal of Wind Engineering and Industrial Aerodynamics2009，97，910： | 1 |
| 15 | Estimating the influ- ence of transport on house prices: Evidence from Hong Kong 显示文摘 | So H M Tse R Y C Ganesan S | 1997 | Journal of Property Valuation and Investment1997，15，： | 1 |
| 16 | General Design Issues of Sliding-mode controllers in DC-DC converters显示文摘 | TAN S C LAI Y M TSE C K | 2008 | IEEE Transactions Power Electronics2008，55，3： | 1 |
| 17 | Pulmonary vein isolation using transvenous catheter cryoablation for the treatment of atrial fibrillation without risk of pulmonary vein stenosis显示文摘 | Tse HF Reek S Timmermanns C | 2003 | J Am Coll Cardiol2003，42，4： | 1 |
| 18 | Use of Prophylactic Lamivudine and Mycophenolate Mofetil in Renal Transplant Recipients with Chronic Hepatitis B Infectioni显示文摘 | Lau S C Tse K C Lai W M | 2003 | Pediatr Transplant2003，7，5： | 1 |
| 19 | Analysis and spectral characteristics of a spread spectrum technique for conducted EMI suppression 显示文摘 | TSE K K CHUNG H S H HUI S Y R | 2000 | IEEE Transactions on Power Electronics2000，15，2： | 1 |
| 20 | SnO2 nanorod arrays: low temperature growth, surface modification and field emission properties 显示文摘 | HUANG H LIM C K TSE M S | 2012 | Nanoscale2012，4，5： | 1 |
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