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172篇 您的检索式:作者名="Tymianski"
    题名 作者 年代 出处 被引量
1Discovery and development of NA-1 for the treatment of acute ischemic stroke显示文摘击包括 excitotoxicity,离子的不平衡,发炎,氧化压力和 apoptosis 创造多重 signaing 小径的复杂相互影响。有很少的治疗,被显示了在急性击有益。最近的调查结果提供了卓见进 ischemic 击的 pathophysiology 和机制,补充传统的 glutamate 假设:在 PSD95 和 GluN2B 之间的分子的相互作用在调停击的 excitotoxicity 作为一个犯人被识别了,导致 NA-1 的发现,破坏那个相互作用,,的肽为急性击的处理的一个有势力 neuroprotective 代理人。在这评论,我们从凳子描述它的发信号的串联,它的治疗学的干预的目标和它的翻译到临床的试用。Beatrice BALLARIN Michael TYMIANSKI 2018Acta Pharmacologica Sinica2018,39,5:26
2Molecular mechanisms of calcium-depen- dent neurodegeneration in exeitotoxieity 显示文摘Anmdine M Tymianski M 2003Cell Calcium2003,34,45:1
3Postsynaptic mechanisms of excitotoxici-ty : Involvement of postsynaptic density proteins,radicals,and oxi-dant molecules显示文摘Forder J P Tymianski M 2009Neuroscience2009,158,1:1
4Nonhuman primate models of stroke for translational neuroprotection research显示文摘Cook D J Tymianski M 2012Neurotherapeuties2012,9,2:1
5Sourcespecificity of early calcium neurotoxicity in cultured embryonic spinal neurons 显示文摘Tymianski M Charhon MP Carlen PL 1993J Neurosci1993,13,5:1
6Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain显示文摘Cook D J Teves L Tymianski M 2012Nature2012,483,7388:1
7The transmastoid Partial labyrinthectomy approach to medial skull base lesions显示文摘Walsh RM Tymianski M Wallace MC 2000Rev Laryngol Otol Rhinol (Bord)2000,121,:1
8Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death显示文摘Sattler R Tymianski M 2001Mol Neurobiol2001,24,13:1
9Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury显示文摘ArundineM Tymianski M 2004Cell Mol Life Sci2004,61,6:1
10Calcium, ischemia and excitotoxicity 显示文摘Szydlowska K Tymianski M 2010Cell Calcium2010,47,2:1
11Molecular mechanisms of glutamate receptor--mediated exeitotoxic neuronal cell death显示文摘Sattler R Tymianski M 2001Mol Neurobiol2001,24,13:1
12TRPMs and neuronal cell death显示文摘Aarts MM Tymianski M 2005Pflugers Arch2005,451,1:1
13Calcium,ischemia and excitotoxicity显示文摘Szydlowska K Tymianski M 2010Cell Calcium2010,47,2:1
14Normal and abnormal calcium homeostasis inneruons :A basis for the pathophysiology of traumatic and ischemic central nervous system injury 显示文摘Tymianski M Taetoor CH 1996Neurosurgery1996,38,6:1
15Emerging mechanisms of disrupted cellular signaling in brain ischemia显示文摘Tymianski M 2011Nat Neurosci2011,14,11:1
16Calcium, isehemia and excitotoxicity 显示文摘Szydlowska K Tymianski M 2010Cell Calcium2010,47,2:1
17Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death显示文摘Sattler R Tymianski M 2001Mol Neurobiol2001,24,13:1
18Determination of the time course and extent of neurotoxicity at defined temperatures in cultured neurons using a modified muhiwell plate fluorescence scanner显示文摘Sattler R Charhon MP Hafner M Tymianski M 1997J Cereb Blood Flow Metab1997,17,4:1
19Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain 显示文摘Tymianski M Cook DJ Teves L 2012Nature2012,483,7388:1
20Glutamate receptors, neurotoxicity and neu- rodegeneration 显示文摘Lau A Tymianski M 2010Pflugers Arch2010,460,2:1
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