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| 1 | Improved guided bone regeneration by combined application of unmodified, fresh autologous adipose derived regenerative cells and plasma rich in growth factors:A first-in-human case report and literature review显示文摘BACKGROUND Novel strategies are needed for improving guided bone regeneration(GBR) in oral surgery prior to implant placement, particularly in maxillary sinus augmentation(GBR-MSA) and in lateral alveolar ridge augmentation(LRA). This study tested the hypothesis that the combination of freshly isolated, unmodified autologous adipose-derived regenerative cells(UA-ADRCs), fraction 2 of plasma rich in growth factors(PRGF-2) and an osteoinductive scaffold(OIS)(UAADRC/PRGF-2/OIS) is superior to the combination of PRGF-2 and the same OIS alone(PRGF-2/OIS) in GBR-MSA/LRA.CASE SUMMARY A 79-year-old patient was treated with a bilateral external sinus lift procedure as well as a bilateral lateral alveolar ridge augmentation. GBR-MSA/LRA was performed with UA-ADRC/PRGF-2/OIS on the right side, and with PRGF-2/OIS on the left side. Biopsies were collected at 6 wk and 34 wk after GBRMSA/LRA. At the latter time point implants were placed. Radiographs(32 mo follow-up time) demonstrated excellent bone healing. No radiological or histological signs of inflammation were observed. Detailed histologic,histomorphometric, and immunohistochemical analysis of the biopsies evidenced that UA-ADRC/PRGF-2/OIS resulted in better and faster bone regeneration than PRGF-2/OIS.CONCLUSION GBR-MSA with UA-ADRCs, PRGF-2, and an OIS shows effectiveness without adverse effects. | ?nder Solakoglu Werner G?tz Maren C Kiessling Christopher Alt Christoph Schmitz Eckhard U Alt | 2019 | World Journal of Stem Cells2019，11，2： | 3 |
| 2 | Bernkop-Schnu″ rch,Evaluation of the inhibitory effect of thiolated poly(acrylates) on vaginal membrane bound aminopeptidase N显示文摘 | C Valenta M Marschu″tz C Egyed | 2002 | J Pharm Pharmacol2002，54，： | 1 |
| 3 | Survival of rapidly frozen hatched mouse blastocysts 显示文摘 | Pribenszky C Cseh S Abonyi TZ | 2003 | Zygote2003，11，4： | 1 |
| 4 | Physiological and structuralchanges in the chloroplast of the green alga Micrasterias den-ticulata induced by UV-B simulation显示文摘 | Lütz C Seidlitz H K Meindl U | 1997 | Plant Ecol1997，128，： | 1 |
| 5 | Does an interspinous device (Coflex)improve the outcome of decompressive surgery in lumbar spinal stenosis One-year follow up of a prospective care control studv of 60 patients显示文摘 | Richter A Schütz C Hauck M | | 0，，： | 1 |
| 6 | Chronic stroke recovery after combined BCI training and physiotherapy:a case report显示文摘 | Caria A Weber C Br(o)tz D | 2011 | Psychophysiology2011，48，4： | 1 |
| 7 | Chronic stroke recovery after combined BCI training and physiotherapy:a case report显示文摘 | Caria A Weber C Br?tz D | 2011 | Psychophysiology2011，48，4： | 1 |
| 8 | Identity elements for specific aminoacylation of yeast tRNA(Asn) by cognate aspartyl-tRNA synthetase显示文摘 | Pütz J Puglisi JD Florentz C | 1991 | Science1991，252，： | 1 |
| 9 | Isolation of precursor cells (PCs) from human dental follicle of wisdom teeth 显示文摘 | Morsczeck C Gtz W Schierholz J | 2005 | Matrix Biol2005，24，2： | 1 |
| 10 | The nuclear receptor superfamily: the second decade显示文摘 | Mangelsdorf DJ Thummel C Beato M Herrlich P Schütz G Umesono K | 1995 | Cell1995，83，6： | 1 |
| 11 | Does an interspinous device(Coflex)improve the outcome of decompressive surgery in lumbar spinal stenosis?One-year follow up of a prospective case control study of 60 patients显示文摘 | Richter A Schütz C Hauck M | 2010 | Eur Spine J2010，19，2： | 1 |
| 12 | Towards an integrated view of HCN channel role in epilepsy显示文摘 | Noam Y Bernard C Baram TZ | 2011 | Curr Opin Neurobiol2011，21，6： | 1 |
| 13 | In vitro differentiation of human dental follicle cells with dexamethasone and insulin显示文摘 | Morsczeck C Moehl C G?tz W | 2005 | Cell Biology International2005，29，7： | 1 |
| 14 | Preoperative anxiety in children predictor and outcomes显示文摘 | Kain ZN Mayes I C O' connor TZ | 1996 | Arch Ped- iatr Adolesc Med1996，，150： | 1 |
| 15 | Preoperative and perioporative care for patients with suspected or established aortic stenosis facing noncardiac surgery显示文摘 | Michael C Yulia S G(o)tz G | 2006 | Chest2006，129，4： | 1 |
| 16 | Fiber Tracking fiom DTI Using I,Linear State Space Models: Detectability of the Pyramideal Traet显示文摘 | Go'ssl C Fahrmeir L Pu' tz B | 2002 | Neurolmage2002，16，： | 1 |
| 17 | Early responses of periodontal ligament cells to mechanical stimulus in vivo显示文摘 | Kawarizadeh A Bourauel C Gtz W | 2005 | J Dent Res2005，84，： | 1 |
| 18 | Effect of the activation temperature on the state of gold supported on titania: an FT-IR Catalysis A: General, 2006, 301(1) spectroscopic study 显示文摘 | Venkov Tz Fajerwerg K Delannoy L Klimev Hr Hadjiivanov K Louisb C | 2006 | Applied2006，，： | 1 |
| 19 | Isolation of precursor cells(PCs) from human dental follicle of wis-dom teeth显示文摘 | Morsczeck C G?tz W Schierholz J | | 0，，02： | 1 |
| 20 | Avoiding and managingbleeding complications in patients with non-ST-segment elevationacute coronary syndromes显示文摘 | Potsis TZ Katsouras C Goudevenos JA | 2009 | Angiology2009，60，2： | 1 |
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