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| 1 | Hepatic steatosis is associated with an increased risk of carotid atherosclerosis显示文摘AIM: Although an association between helatic steatosis and vascular risk factors has been described, direct relationships between fatty liver and atherosclerosis have not yet been investigated. The aim of the present study has been to investigate those relationships.METHODS: The Study of Health in Pomerania examined a random population sample aged between 20 and 79 years.A study population of 4 222 subjects without hepatitis B and C infections and without liver cirrhosis was available for the present analysis. Hepatic steatosis was defined sonographically and intima-media thickness (IMT) as well as plaque prevalence were estimated by carotid ultrasound.RESULTS: The prevalence rate of hepatic steatosis was 29.9%. Among subjects aged ≥45 years, an association between hepatic steatosis and IMT of the carotid arteries was found in bivariate analysis, but not after adjustment for atherosclerotic risk factors. Individuals with fatty liver had more often carotid plaques than persons without fatty liver (plaque prevalence rate 76.8% vs 66.6%; P<0.001).This association persisted after adjustment for confounding factors and was predominantly present in subjects with no to mild alcohol consumption.CONCLUSION: There is an independent association between hepatic steatosis and carotid atherosclerotic plaques. Metabolic changes due to nonalcoholic fatty liver disease may explain this relationship. | Henry V(o|¨)lzke Daniel M.Robinson Volker Kleine Roland Deutscher Wolfgang Hoffmann Jan Lüdemann Ulf Schminke Christof Kessler Ulrich John | 2005 | World Journal of Gastroenterology2005，11，12： | 29 |
| 2 | Association between thyroid function and gallstone disease显示文摘AIM: To investigate those associations using data of the population-based Study of Health in Pomerania.METHODS: A study population of 3 749 residents aged 20-79 years without previously diagnosed thyroid disease was available for analyses. Serum TSH was used to assess thyroid function. Cholelithiasis was defined by either a prior history of cholecystectomy or the presence of gallstones on ultrasound. Logistic regression was performed to analyze independent associations between thyroid function and cholelithiasis.RESULTS: There were 385 persons (10.3%) with low (<0.3 mIU/L), 3 321 persons (88.6%) with normal and 43 persons (1.2%) with high serum TSH levels (>3 mIU/L).The proportion of cholelithiasis among males and females was 14.4% and 25.3%, respectively. Among males, there was an independent relation between high serum TSH and cholelithiasis (OR 3.77; 95%-CI 1.06-13.41; ,P<0.05). zAlso among males, there was a tendency towards an elevated risk of cholelithiasis in persons with low serum TSH (OR 1.40; 95%-CI 0.96-2.02; P = 0.07). In the female population, no such relation was identified.CONCLUSION: There is an association between thyroid and gallstone disease with a gender-specific relation between hypothyroidism and cholelithiasis. | Henry Vlzke Daniel M Robinson Ulrich John | 2005 | World Journal of Gastroenterology2005，11，35： | 8 |
| 3 | 为恶意、良性的胆汁的苛评的治疗的充分盖住的自我可扩充的金属 stents显示文摘 AIM:To present a series of covered self-expandable metal stents(CSEMS) placed for different indications and to evaluate the effectiveness,complications and extractability of these devices.METHODS:We therefore retrospectively reviewed the courses of patients who received CSEMS due to malignant as well as benign biliary strictures and postsphincterotomy bleeding in our endoscopic unit between January 2010 and October 2011.RESULTS:Twenty-six patients received 28 stents due to different indications(20 stents due to malignant biliary strictures,six stents due to benign biliary strictures and two stents due to post-sphincterotomy bleeding).Biliary obstruction was relieved in all cases,regardless of the underlying cause.Hemostasis could be achieved in the two patients who received the stents for this purpose.Complications occurred in five patients(18%).Two patients(7%) developed cholecystitis,stents dislocated/migrated in other two patients(7%),and in one patient(3.6%) stent occlusion was documented during the study period.Seven stents were extracted endoscopically.Removal of stents was easily possible in all cases in which it was desired using standard forceps.Twelve patients underwent surgery with pylorus preserving duodenopancreatectomy.In all patients stents could be removed during the operation without difficulties.CONCLUSION:Despite the higher costs of these devices,fully covered self-expanding metal stents may be suitable to relief biliary obstruction due to bile duct stenosis,regardless of the underlying cause.CSEMS may also represent an effective treatment strategy of severe post-sphincterotomy bleeding,not controlled by other measures. | Ahmed Abdel Samie Stephan Dette Ulrich Vhringer Michael Stumpf Karolin Kopischke Lorenz Theilmann | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，9： | 5 |
| 4 | Prospective evaluation of small bowel preparation with bisacodyl and sodium phosphate for capsule endoscopy显示文摘AIM: To determine the effect of Prepacol?, a com- bination of sodium phosphate and bisacodyl, on transit and quality of capsule endoscopy (CE). METHODS: Fivety two consecutive patients were included in this prospective study. CE was performed following a 12 h fasting period. Twenty six patients were randomized for additional preparation with Prepacol?. The quality of CE was assessed separately for the proximal and the distal small bowel by 3 experienced endoscopists on the basis of a graduation which was initially developed with 20 previous CE. RESULTS: Preparation with Prepacol? accelerated small bowel transit time (262 ± 55 min vs 287 ± 97 min), but had no effect on the quality of CE. Visibility was significantly reduced in the distal compared to the proximal small bowel. CONCLUSION: The significantly reduced visibility of CE in the distal small bowel allocates the need for a good preparation. Since Prepacol? has no beneficial effect on CE the modality of preparation and the ideal time of application remains unclear. Further standardized examinations are necessary to identify sufficient preparation procedures and to determine the impact of the volume of the preparation solution. | Andreas Franke Frank Hummel Phillip Knebel Christoph Antoni Ulrich Bcker Manfred V Singer Matthias Lhr | 2008 | World Journal of Gastroenterology2008，14，13： | 5 |
| 5 | Monitoring of atmospheric deposition in European forests and an overview on its implication on forest condition显示文摘 | Fisher R Mues V Ulrich E | 2007 | Applied Geochemistry2007，22，6： | 1 |
| 6 | PPARgamma is a key target of butyrate-induced Casepase-3-3 activation in the colorectal cancer cell line Caco-2 显示文摘 | Schwab M Reynders V Ulrich S | 2006 | Apoptosis2006，11，10： | 1 |
| 7 | Organically modified aluminosilicate mesostructures from block copolymer phases显示文摘 | TEMPLIN M FRANCK A DUCHESNE A LEIST H ZHANG Y M ULRICH R SCHADLER V WIESNER U | 1997 | Science1997，278，5344： | 1 |
| 8 | Raman spectroscopy on amorphous carbon films 显示文摘 | Schwan J Ulrich S Batori V Ehrhardt H Silva SRP | 1996 | Journal of Applied Physics1996，80，： | 1 |
| 9 | Natural xenophile antibodies from sera of type I diabetic patients differ strongly in their reactivity again various porcine pancreatic cells显示文摘 | Ulrichs K Meincke G | 1992 | Transp Proc1992，24，： | 1 |
| 10 | Customer education: A new frontier for Human Resource Development 显示文摘 | Noel J L Ulrich D Mercer S V | 1990 | Human Resource Management1990，29，4： | 1 |
| 11 | C-myc,not HER-2/neu,can predict recurrence and mortality of patients with node-negative breast cancer显示文摘 | Claus MS Ulf V Ulrich BZ | 2003 | Breast Cancer Res2003，5，： | 1 |
| 12 | Product development deci- sions:a review of the literature显示文摘 | KRISHNAN V ULRICH K T | 2001 | Management Science2001，47，1： | 1 |
| 13 | Natural xenophile antibodies from sera type I diabetic patients differ strongly in their reactivity against various porcine pancreatic cells显示文摘 | Ulrichs K Meincke G | 1992 | Transp Proc1992，24，： | 1 |
| 14 | Raman spectroscopy on amorphous carbon films 显示文摘 | SCHWAN J ULRICH S BATORI V | 1996 | Journal of Applied Physics1996，80，2： | 1 |
| 15 | Raman spectroscopy on amorphous carbon films显示文摘 | Schwan J Ulrich S Batori V | 1996 | J Appl Phys1996，80，1： | 1 |
| 16 | TiO2 thick films supported on reticulated macroporous Al2O3 foams and their photoactivity in phenol mineralization显示文摘 | Melinda V Gustav P Ulrich F V | | 0，，： | 1 |
| 17 | Enolase from Trypanosoma brucei, from the amitochondriate protist Mastigamoeba balamuthi, and from the chloroplast and cytosol of Euglena gracilis: pieces in the evolutionary puzzle of the eukaryotic glyeolytie pathway显示文摘 | Hannaert V Henner B Ulrich N et ol | 2000 | Mol Biol Evol2000，17，7： | 1 |
| 18 | Organo-ruthenium supported heteropo ytungstates:synthesis,structure,electrochemistry,and oxidation catalysis显示文摘 | Bi L A1-Kadamany G Chubarova E V Dickman M H Chen L Gopala D S Richards R M Keita B Nadjo L Jaensch H Mathys G Ulrich Kortz U | | 0，，： | 1 |
| 19 | Raman spectroscopy on amorphous carbon films 显示文摘 | SCHWAN J ULRICH S BATORI V | 1996 | Journal of Applied Physics1996，80，1： | 1 |
| 20 | Product Development Decisions: A Review of the Literature显示文摘 | Krishnan V Ulrich KT | 2001 | Management Science2001，，47： | 1 |
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