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| 1 | Single balloon enteroscopy for endoscopic retrograde cholangiography in patients with Roux-en-Y hepaticojejuno anastomosis显示文摘AIM:To evaluate single balloon enteroscopy in diagnostic and therapeutic endoscopic retrograde cholangiography(ERC)in patients with Roux-en-Y hepaticojejunoanastomosis(HJA).METHODS:The study took place from January 2009to December 2011 and we retrospectively assessed 15patients with Roux-en-Y HJA who had signs of biliary obstruction.In total,23 ERC procedures were performed in these patients and a single balloon videoen-teroscope(Olympus SIF Q 180)was used in all of the cases.A transparent overtube was drawn over the videoenteroscope and it freely moved on the working part of the enteroscope.Its distal end was equipped with a silicone balloon that was inflated by air from an external pump at a pressure of≤5.4 kPa.The technical limitations or rather the parameters of the single balloon enteroscope(working length-200 cm,diameter of the working channel-2.8 mm,absence of Albarran bridge)showed the need for special endoscopic instrumentation.RESULTS:Cannulation success was reached in diagnostic ERC in 12 of 15 patients.ERC findings were normal in 1 of 12 patients.ERC in the remaining 11 patients showed some pathological changes.One of these(cystic bile duct dilation)was subsequently resolved surgically.Endoscopic treatment was initialized in the remaining 10 patients(5 with HJA stenosis,2 with choledocholithiasis,and 3 with both).This treatment was successful in 9 of 10 patients.The endoscopic therapeutic procedures included:balloon dilatation of HJA stenosis-11 times(7 patients);choledocholitiasis extraction-five times(5 patients);biliary plastic stent placement-six times(4 patients);and removal of biliary stents placed by us-six times(4 patients).The mean time of performing a single ERC was 72 min.The longest procedure took 110 min and the shortest took34 min.This shows that it is necessary to allow for more time in individual procedures.Furthermore,these procedures require the presence of an anesthesiologist.We did not observe any complications in these 15 patients.CONCLUSION:This method is more demanding than standard endoscopic retrograde cholangiopancreatography due to altered postsurgical anatomy.However,it is effective,safe,and widens the possibilities of resolving biliary pathology. | Bohuslav Kianika Jan Lata Ivo Novotny Petr Dítě Jirí Vaníek | 2013 | World Journal of Gastroenterology2013，19，44： | 2 |
| 2 | Toward Carbon-Neutral Water Systems:Insights from Global Cities显示文摘Many cities have pledged to achieve carbon neutrality.The urban water industry can also contribute its share to a carbon-neutral future.Using a multi-city time-series analysis approach,this study aims to assess the progress and lessons learned from the greenhouse gas(GHG)emissions management of urban water systems in four global cities:Amsterdam,Melbourne,New York City,and Tokyo.These cities are advanced in setting GHG emissions reduction targets and reporting GHG emissions in their water industries.All four cities have reduced the GHG emissions in their water industries,compared with those from more than a decade ago(i.e.,the latest three-year moving averages are 13%–32%lower),although the emissions have“rebounded”multiple times over the years.The emissions reductions were mainly due to various engineering opportunities such as solar and mini-hydro power generation,biogas valorization,sludge digestion and incineration optimization,and aeration system optimization.These cities have recognized the many challenges in reaching carbon-neutrality goals,which include fluctuating water demand and rainfall,more carbon-intensive flood-prevention and water-supply strategies,meeting new air and water quality standards,and revising GHG emissions accounting methods.This study has also shown that it is difficult for the water industry to achieve carbon neutrality on its own.A collaborative approach with other sectors is needed when aiming toward the city’s carbon-neutrality goal.Such an approach involves expanding the usual system boundary of the water industry to externally tap into both engineering and non-engineering opportunities. | Ka Leung Lam Gang Liu Anne Marieke Motelica-Wagenaar Jan Peter van der Hoek | 2022 | Engineering2022，8，7： | 2 |
| 3 | Defining the nature of human pluripotent stem cell progeny显示文摘当人的 pluripotent 干细胞(hPSCs ) 能区分产生各种各样的房间类型的一件礼服,是清楚的时,在 vitro,开发怎么仔细反射那,是未知的哪个发生在 vivo。决定人的胚胎的干细胞(hESCs ) 和导致人的 pluripotent 干细胞(hiPSCs ) 是否做相等的子孙,并且是否也使房间成为那类似于导出织物的房间,我们执行了净化的 PSC 衍生物和他们的导出织物的对应物介绍的全面 transcriptome。表示介绍证明 hESCs 和 hiPSCs 在 hiPSC 子孙用外长的 reprogramming 因素为重新表示的神经、肝、间充质的系,和缺席做将近相同的子孙。不管多么与一个导出织物的对应物相比, hESCs 和 hiPSCs 的子孙维持了通常与早哺乳动物的开发联系的基因的一个子集的表示,不管产生的房间的类型。当 pluripotent 基因(OCT4, SOX2, REX1,和 NANOG ) 看起来在从 hPSCs 的区别之上立即是 silenced 时,对早胚胎(LIN28A, LIN28B, DPPA4,和其它) 通常独特的基因不是充分在 hPSC 衍生物的 silenced。从在早人的胎儿的织物(开发的 3-16 星期) 的表达式模式的这些数据和证据建议 hPSCs 的区分的子孙很早人的开发是反射的(< 6 个星期) 。这些调查结果为 hPSCs 能在早人的开发的 vitro 模型作为有用服务的想法提供支持,而且为疾病建模和 hPSC 衍生物的临床的申请提出重要问题。 | Michaela Patterson David N Chan IrisHa Dana Case Yongyan Cui Ben Van Hande Hanna KA Mikkola William E Lowry | 2012 | Cell Research2012，22，1： | 2 |
| 4 | A novel sodium channel mutation in a family with hypokalemic periodic paralysis显示文摘 | Bulman DE Scoggan KA van Oene MD etal | 1999 | Neurology1999，53，9： | 1 |
| 5 | Maternal perinatal depression is not independently associated with child body mass index in the Generation R Study:methods and missing data matter显示文摘 | Ertel KA Kleinman K van Rossem L | 2012 | J Clin Epidemiol2012，65，12： | 1 |
| 6 | Flow regulation of collecting duct endothelin-1 production显示文摘 | Lyon-Roberts B Strait KA van Peursem E | 2011 | Am J Physiol Renal Physiol2011，300，3： | 1 |
| 7 | Managing HIV among serodicosrdant heterosexual couples:serostatus,stigma and sex 显示文摘 | Van der Straten A Vemon KA Knight KR | 1998 | AIDS Care1998，10，5： | 1 |
| 8 | A replication and extension of the PEERS intervention:examining effects on social skills and social anxiety in adolescents with autism spectrum disorders显示文摘 | Schohl KA Van Hecke AV Carson AM | 2014 | J Autism Dev Disord2014，44，3： | 1 |
| 9 | Individual and interactive effects of apigenin analogs on G2/M cell-cycle arrest in human colon carcinoma cell lines显示文摘 | Wang W Van Alstyne PC Irons KA | 2004 | Nutr Cancer2004，48，1： | 1 |
| 10 | Sunitinib treatment in pediatric patients with advanced GIST following failure of imatinib 显示文摘 | Janeway KA Albritton KH Van Den Abbeele AD | 2009 | Pediatr Blood Cancer2009，52，7： | 1 |
| 11 | Baerveldt Glaucoma implant in paediatric patients 显示文摘 | Van Overdam KA de Faber JT Lemij HG | 2006 | Ophthal mol2006，90，3： | 1 |
| 12 | Allogeneic bone marrow transplantation for refractory and recurrent low-grade lymphoma: the case for aggressive management显示文摘 | van Besien KW Rowlings PA Sobocinski KA | 1995 | Proc Am Soc Clin Oncol1995，14，： | 1 |
| 13 | Reciprocal regulation of myocardial micro RNAs and messenger RNA in human cardiomyopathy and reversal of the micro RNA signature by biomechanical support显示文摘 | Matkovich SJ Van Booven DJ Youker KA | 2009 | Circulation2009，119，9： | 1 |
| 14 | Evaluation of cell responses toward adhesives with different photoinitiating systems显示文摘 | Van Landuyt KL Krifka S Hiller KA | 2015 | Dent Mater2015，31，8： | 1 |
| 15 | Comparative study of specific groundwater vulnerabili-ty of a karst aquifer in central Florida 显示文摘 | VAN BEYNEN P E NIEDZIELSKI M A BIALKOWSKA-JELINS- KA E | 2012 | Applied Geography2012，32，2： | 1 |
| 16 | Reciprocal regulation of myocardial microRNAs and messenger RNA in human cardiomyopathy and reversal of the microRNA signature by biomechanical support显示文摘 | Matkovich SJ Van Booven DJ Youker KA | 2009 | Circulation2009，119，9： | 1 |
| 17 | Cardiospecific sevo- flurane treatment quenches inflammation but does not attenuate myocardial cell damage markers: a proof-of-concept study in pa- tients undergoing mitral valve repair 显示文摘 | Kortekaas KA van der Baan A Aarts LP | 2014 | Br J Anaesth2014，112，6： | 1 |
| 18 | Depletion of taurine in experimental diabetic neuropathy implications for nerve metabolic vas- cular and functional deficits 显示文摘 | Pop-Busui R Sullivan KA Van Huysen C | 2001 | Exp Neurol2001，168，2： | 1 |
| 19 | Molecular genetic testing from paraffin-embedded tissue distinguishes nonmolar hydropic abortion from hydatidiform mole显示文摘 | Bell KA Van DV Addya K | 1999 | Mol Diagn1999，4，： | 1 |
| 20 | Update in the management of aortic dissection显示文摘 | TOLENAAR JL van BOGERIJEN GH EAGLE KA | 2013 | Curr Treat Options Cardiovasc Med2013，15，2： | 1 |
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