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	题名	作者	年代	出处	被引量
1	通过手术导致的重量损失由胃绕过在疾病的肥胖的病人改进非含酒精的脂肪肝疾病显示文摘 AIM:To evaluate the effects of surgical weight loss(Roux-en-Y gastric bypass with a modified Fobi-Capella technique) on non alcoholic fatty liver disease in obese patients.METHODS:A group of 26 morbidly obese patients aged 45 ± 2 years and with a body mass index > 40 kg/m 2 who underwent open surgical weight loss operations had paired liver biopsies,the first at surgery and the second after 16 ± 3 mo of weight loss.Biopsies were evaluated and compared in a blinded fashion.The presence of metabolic syndrome,anthropometric and biochemical variables were also assessed at baseline and at the time of the second biopsy.RESULTS:Percentage of excess weight loss was 72.1% ± 6.6%.There was a reduction in prevalence of metabolic syndrome from 57.7%(15 patients) to 7.7%(2 patients)(P < 0.001).Any significance difference was observed in aspartate aminotransferase or alanine aminotransferase between pre and postsurgery.There were improvements in steatosis(P < 0.001),lobular(P < 0.001) and portal(P < 0.05) inflammation and fibrosis(P < 0.001) at the second biopsy.There were 25(96.1%) patients with non alcoholic steatohepatitis(NASH) in their index biopsy and only four(15.3%) of the repeat biopsies fulfilled the criteria for NASH.The persistence of fibrosis(F > 1) was present in five patients at second biopsy.Steatosis and fibrosis at surgery were predictors of significant fibrosis postsurgery.CONCLUSION:Restrictive mildly malabsorptive surgery provides significant weight loss,resolution of metabolic syndrome and associated abnormal liver histological features in most obese patients.	Víctor Vargas Helena Allende Albert Lecube Maria Teresa Salcedo Juan A Baena-Fustegueras José M Fort Joaquín Rivero Roser Ferrer Roberto Catalán Eva Pardina Santiago Ramón y Cajal Jaime Guardia Julia Peinado-Onsurbe	2012	World Journal of Hepatology2012，4，12：	6
2	CD70^+ anti gen-presenting cells control the proliferation and differentiation of T cells in the intestinal mucosa显示文摘	Laouar A Haridas V Vargas D	2005	Nat Immunol2005，6，：	1
3	Phenology and Phenotypic Natural Selection on the Flowering Time of a DeceitPollinated Tropical Orchid, MyrmecoptLila christinae 显示文摘	PARRA TABLA V VARGAS M F	2004	Annals of Botany2004，94，2：	1
4	Clinical consequences of infection in patients with acute stroke: is it prime time for further antibiotic trials? 显示文摘	Vargas M Horcajada JP Obach V	2006	Stroke2006，37，2：	1
5	State of the art of minimally invasive breast biopsy: principles and practice显示文摘	Vargas H I Agbunag R V Khaikhali I	2000	Breast Cancer2000，7，4：	1
6	Mutagenic activity as a parameter to asses ambi-ent air quality for protection of the environment and human health显示文摘	Vargas V M		0，，：	1
7	Thermodynamic optimization of finned crossflow heat exchangers for aircraft environmental control systems显示文摘	Vargas J V C Bejan A	2001	International Journal of Heat and Fluid Flow2001，22，6：	1
8	Role of the tumor markers CA 199 and carcinoembryonic antigen(CEA)in diagnosis,treatment and prognosis of pancreatic cancer显示文摘	Kokhanenko N U Ignashov A M Varga E V	2001	Vopr Onkol2001，47，3：	1
9	Atherosclerosis and vascular calcification in chronic renal failure显示文摘	Campean V Neureiter D Varga I	2005	Kidney Blood Press Res2005，28，56：	1
10	Automated virtual microscopy of gastric biopsies显示文摘	Ficsor L Varga V Berczi L	2006	Cytometry B Clin C ytom2006，70，6：	1
11	Genetic correlations and simultaneous selection for growth and wood density in Pinus patula显示文摘	Valencia M S Vargas H J Manzo J V	2001	Agrociencia2001，35，1：	1
12	Clinical consequences of infection in patients with acute stroke:is it prime time for further antibiotic trials?显示文摘	Vargas M Horcajada JP Obach V	2006	Stroke2006，37，：	1
13	Optimi- zation study and heat transfer comparison of staggered circular and elliptic tubes in forced convection 显示文摘	Matos R S Vargas J V C Laursen T A	2001	International Journal of Heat and Mass Transfer2001，44，20：	1
14	Cooperative action of attached and planktonic cells during bioleaching of chalcopyrite with Sulfolobus metallicus at 70 ℃ 显示文摘	Gautier V Escobar B Vargas T	2008	Hydrometallurgy2008，94，1234：	1
15	Comparative analysis of D2-40 and LYVE-1 immunostaining in lymphatic malformations显示文摘	FLOREZ VARGAS A VARGAS S O DEBELENKO L V	2008	Lymphology2008，41，3：	1
16	Determination of Organic Acids in Xylem Sap of Cucumber:Effect of Lead Contamination显示文摘	Tátar E Mihucz V G Varga A	1998	Microchemi J1998，58，：	1
17	Gains of chromosome 8 are confined to mesenchymal components in pleuropulmonary blastoma显示文摘	Vargas S 0 Nose V Fletcher J A	2001	Pediatr Dev Patho12001，4，5：	1
18	Integrative thermodynamic optimization of the crossflow heat exchanger for an aircraft environmental control system 显示文摘	BEJAN A SIEMS D L	2001	Trans ASME:J Heat Transfer2001，123，4：	1
19	Clinical consequences of infection in patients with acute stroke : is it prime for further antibintic triM? 显示文摘	Vargas M Horcajada JP Obach V	2006	Stroke2006，37，：	1
20	Imaging of osteomyelitis:current concepts显示文摘	Pineda C Vargas A Rodriguez A V	2006	Infect Dis Clin North Am2006，20，4：	1

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