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44篇 您的检索式:作者名="VELHO S"
    题名 作者 年代 出处 被引量
1Causes and consequences of microsatellite instability in gastric carcinogenesis显示文摘Loss of DNA mismatch repair(MMR) function, due to somatic or germline epi/genetic alterations of MMR genes leads to the accumulation of numerous mutations across the genome, creating a molecular phenotype known as microsatellite instability(MSI). In gastric cancer(g C), MSI occurs in about 15% to 30% of the cases. This review summarizes the current knowledge on the molecular mechanisms underlying the acquisition of MSI in g C as well as on the clinic, pathologic and molecular consequences of the MSI phenotype. Additionally, current therapeutic strategies for g C and their applicability in the MSI subset are also discussed.Sérgia Velho Maria Sofia Fernandes Marina Leite Ceu Figueiredo Raquel Seruca 2014World Journal of Gastroenterology2014,20,44:14
2Oncogenic mutations in gastric cancer with microsatellite instability显示文摘Corso G Velho S Paredes J European Journal of Cancer0,47,3:1
3Concomitant RASSF1Ahypermethylation and KRAS/BRAF mutations occur preferentiallyin MSI sporadic colorectal cancer显示文摘Oliveira C Velho S Domingo E 2005Oncogene2005,24,51:1
4Evidence of tumor microsatellite instability in gastric cancer with familial aggregation显示文摘Corrado Pedrazzani Giovanni Corso Sérgia Velho Marina Leite Valeria Pascale Francesca Bettarini Daniele Marrelli Raquel Seruca Franco Roviello 2009Familial Cancer2009,,3:1
5Zooplankton communitymetrics as indicators of eutrophication in urban lakes显示文摘LODI S VIEIRA L C G VELHO L F M 2011Brazilian Jour-nal of Nature Conservation2011,9,1:1
6Induction of hippocampal long-term potentiation during waking leads to increased extrahippocampal zif-268 expression during ensuing rapid-eye-movement sleep显示文摘Ribeiro S Mello CV Velho T 0,,:1
7BRAF,KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in eolorectal carcinogenesis 显示文摘Velho S Moutinho C Cirnes L 2008BMC Cancer2008,8,:1
8Zooplankton community metrics as indicators of eutrophication in urban lakes显示文摘LODI S VIEIRA L C G VELHO L F M 2011Brazilian Journal of Nature Conservation2011,9,1:1
9Mutant N-RAS protects colorectal cancer cells from stress-induced ap- optosis and contributes to cancer development and pro- gression显示文摘Wang Y Velho S Vakiani E 2013Cancer Disc2013,3,3:1
10Concomitant RASSF1A hypermethylation and K-RAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer显示文摘OLIVEIRA C VELHO S DOMINGO E 0,,51:1
11The prevalence of PIK3CA mutations in gastric and colon cancer显示文摘Velho S Oliveira C Ferreira A 2005Eur J Cancer2005,41,11:1
12Oncogenic mutations in gastric cancer with mietosatellite instability 显示文摘Corso G Velho S Peredes J 2011Eur J Cancer2011,47,:1
13BRAF,KRAS and PIK3CA mutations in colorectal serrated polyps and cancer:primary or secondary genetic events in colorectal carcinogenesis?显示文摘Velho S Moutinho C Cirnes L 2008BMC Cancer2008,9,8:1
14Concomitant RASSF1A hypermethylation and K-RAS/BRAF mutations occur pref- erentially in MSI sporadic colorectal cancer显示文摘Oliveira C Velho S Domingo E 2005Oncogene2005,24,51:1
15The prevalence of PIK3CA mutations in gastric and colon cancer显示文摘Velho S Oliveira C Ferreira A 2005Eur J Cancer2005,41,11:1
16Plasma copeptin and renal outcomes in patients with type 2 diabetes and ali)uminuria显示文摘Velho G Houby N Hadjadj S 2013Diabetes Care2013,36,11:1
17B-Raf(V60OE) co- operates with alternative spliced Raclb to sustain colorec- tal cancer cell survival 显示文摘Matos P Oliveira C Velho S 2008Gastroenterology2008,135,3:1
18A hierarchical segmentation of articulated bodies显示文摘De GOES F GOLDENSTEIN S VELHO L 2008Computer Graphics Forum Special Issue of Symposium on Geometry Processing2008,27,5:1
19The prevalence of PIK3CA mutations in gastric and colon cancer 显示文摘Velho S Oliveira C Ferreira A 2005Eur J Cancer2005,41,11:1
20Oncogenic mutations in gastric cancer with microsatellite instability显示文摘Corso G Velho S Paredes J 0,,:1
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