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| 1 | TME术前短程放疗后化疗对比术前放化疗联合术后辅助化疗治疗局部晚期直肠癌(RAPIDO研究)—一项随机、开放的Ⅲ期临床试验显示文摘背景:全身复发仍然是局部晚期直肠癌患者需要面临的难题。该研究是采用短程放疗后行化疗和延迟手术对比术前诱导治疗后直接手术疗效的临床试验(the Rectal cancer And Preoperative Induction therapy followed by Dedicated Operation,RAPIDO),旨在不影响局部控制效果的前提下减少远处转移。方法:在这项多中心、随机、开放的Ⅲ期试验中,参与者来自于荷兰、瑞典、西班牙、斯洛文尼亚、丹麦、挪威和美国的共54个医学中心。纳入患者年龄在18岁及以上,ECOG评分为0~1分,且为经活检确诊局部晚期原发直肠腺癌的初诊患者,盆腔MRI评估为高危(至少符合一项标准:cT4a或cT4b,壁外血管侵犯,cN2,直肠系膜筋膜受累,或侧方淋巴结增大)。患者具备化疗适应证,并可在随机分组前5周内完成分期评估。 | 李来元 张维胜 BAHADOER R R DIJKSTRA E A VAN ETTEN B | 2021 | 结直肠肛门外科2021,27,1: | 72 |
| 2 | Selecting suitable solid organ transplant donors: Reducing the risk of donor-transmitted infections显示文摘Selection of the appropriate donor is essential to a successful allograft recipient outcome for solid organ transplantation. Multiple infectious diseases have been transmitted from the donor to the recipient via transplantation. Donor-transmitted infections cause increased morbidity and mortality to the recipient. In recent years, a series of high-profile transmissions of infections have occurred in organ recipients prompt-ing increased attention on the process of improving the selection of an appropriate donor that balances the shortage of needed allografts with an approach that mitigates the risk of donor-transmitted infection to the recipient. Important advances focused on improving donor screening diagnostics, using previously excluded high-risk donors, and individualizing the selection of allografts to recipients based on their prior infection history are serving to increase the donor pool and improve outcomes after transplant. This article serves to review the relevant literature surrounding this topic and to provide a suggested approach to the selection of an appropriate solid organ transplant donor. | Christopher S Kovacs Jr Christine E Koval David van Duin Amanda Guedes de Morais Blanca E Gonzalez Robin K Avery Steven D Mawhorter Kyle D Brizendine Eric D Cober Cyndee Miranda Rabin K Shrestha Lucileia Teixeira Sherif B Mossad | 2014 | World Journal of Transplantation2014,4,2: | 7 |
| 3 | Artificial intelligence in gastroenterology: A state-of-the-art review显示文摘The development of artificial intelligence(AI)has increased dramatically in the last 20 years,with clinical applications progressively being explored for most of the medical specialties.The field of gastroenterology and hepatology,substantially reliant on vast amounts of imaging studies,is not an exception.The clinical applications of AI systems in this field include the identification of premalignant or malignant lesions(e.g.,identification of dysplasia or esophageal adenocarcinoma in Barrett’s esophagus,pancreatic malignancies),detection of lesions(e.g.,polyp identification and classification,small-bowel bleeding lesion on capsule endoscopy,pancreatic cystic lesions),development of objective scoring systems for risk stratification,predicting disease prognosis or treatment response[e.g.,determining survival in patients post-resection of hepatocellular carcinoma),determining which patients with inflammatory bowel disease(IBD)will benefit from biologic therapy],or evaluation of metrics such as bowel preparation score or quality of endoscopic examination.The objective of this comprehensive review is to analyze the available AI-related studies pertaining to the entirety of the gastrointestinal tract,including the upper,middle and lower tracts;IBD;the hepatobiliary system;and the pancreas,discussing the findings and clinical applications,as well as outlining the current limitations and future directions in this field. | Paul T Kröner Megan ML Engels Benjamin S Glicksberg Kipp W Johnson Obaie Mzaik Jeanin E van Hooft Michael B Wallace Hashem B El-Serag Chayakrit Krittanawong | 2021 | World Journal of Gastroenterology2021,27,40: | 6 |
| 4 | CD 64 distinguishes macrophages from dendritic cells in the gut and reveals the T h1‐inducing role of mesenteric lymph node macrophages during colitis显示文摘 | Samira Tamoutounour Sandrine Henri Hugues Lelouard Béatrice de Bovis Colin de Haar C. Janneke van der Woude Andrea M. Woltman Yasmin Reyal Dominique Bonnet Dorine Sichien Calum C. Bain Allan McI. Mowat Caetano Reis e Sousa Lionel F. Poulin Bernard Malisse | 2012 | Eur J Immunol2012,,12: | 2 |
| 5 | Comparison of exercise electrocardiography and dobutamine echocardiography with invasively assessed myocardial fractional flow reserve in evaluation of severity of coronary arterial narrowing显示文摘 | Bartunek J Van Schuerbeeck E De Bruyne B | | Am J Cardiol0,1,: | 2 |
| 6 | Overexpression of a novel Arabidopsis gene related to putative zinc-transporter genes from animals can lead to enhanced zinc resistance and accumulation显示文摘 | VAN DER ZAAL B J NEUTEBOOM L W PINAS J E | 1999 | Plant Physiology1999,119,: | 1 |
| 7 | An autonomous robot for de-leafing cucumber plants grown in a high-wire cultivation system显示文摘 | van Henten E J van Tuijl B A J Hoogakker G J | 2006 | Biosystems Engineering2006,94,3: | 1 |
| 8 | Molecular pharmacology of vitamin E: Structural aspects of antioxidant activity显示文摘 | Van Acker S A B E Koymans L M H Bast A | 1993 | Free Radical Biology and Medicine1993,15,: | 1 |
| 9 | Effects of organic forms of zinc on growth performance,tissue zinc distribution,and immune response of weanling pigs显示文摘 | Van Heugten E T Spears J W Kegley E B | 2003 | J Anim Sci2003,81,: | 1 |
| 10 | Pulmonary embolism:valiclition of spiral CT angiography in 149 patients显示文摘 | Van Rossum A B Pattynama P M Ton E R | 1996 | Radiology1996,201,2: | 1 |
| 11 | Patterns of interdependence in work teams: A two-level investigation of the relations with job and team satisfaction 显示文摘 | Van Der Vegt G S Emans B J M Van De Vliert E | 2001 | Personnel Psychology2001,54,1: | 1 |
| 12 | Polymorphisms in CYP1B1,GSTM1,GSTT1 and GSTP1,and susceptibility to breast cancer显示文摘 | VAN EMBURGH B O HU J J LEVINE E A | | 0,,05: | 1 |
| 13 | Lignan contents of Dutch plant foods: a database including lariciresinol, pinoresinol, secoisolariciresinol and matairesinol显示文摘 | MILDER I E J ARTS I C W van de PUTTE B | 2005 | British Journal of Nutrition2005,93,3: | 1 |
| 14 | Clinical recommendations on the treatment of neuroendoerine carcinoma of the larynx: A meta-analysis of 436 reported cases显示文摘 | VAN DER LAAN T P PLAAT B E VAN DER LAAN B F | 2015 | Head Neck2015,37,: | 1 |
| 15 | Automatic segmentation of pulmonary segments from volumetric chest CT scans 显示文摘 | Van Rikxoort E M de Hoop B van de Vorst S ProkopM van Ginneken B | 2009 | Medical Imaging IEEE Transactions on2009,28,4: | 1 |
| 16 | Three-dimensional vortex organization in a high-Reynolds-number supersonic turbulent boundary layer显示文摘 | Elsinga G E Adrian R J Van Oudheusden B W | 2010 | J Fluid Mech2010,644,: | 1 |
| 17 | Flow regulation of collecting duct endothelin-1 production显示文摘 | Lyon-Roberts B Strait KA van Peursem E | 2011 | Am J Physiol Renal Physiol2011,300,3: | 1 |
| 18 | Predictors of survival for esophageal cancer patients with and without celiac axis lymphadenopathy: impact of staging endosonography显示文摘 | Mohamad A Eloubeidi Michael B Wallace Brenda J Hoffman Margaret B Leveen Annette Van Velse Robert H Hawes Carolyn E Reed | 2001 | The Annals of Thoracic Surgery2001,,1: | 1 |
| 19 | Does chemotherapy prior to liver resection increase the potential for cure in patients with metastatic coloreetal cancer? A report from the european colorectal metastases treatment group 显示文摘 | Nordlinger B Van Cutsem E Rougier P | 2007 | Eur J Cancer2007,43,14: | 1 |
| 20 | Towards a pan-European consensus on the treatment of patients with colorectal liver metastases 显示文摘 | Van Cutsem E Nordlinger B Adam R | 2006 | Eur J Cancer2006,42,14: | 1 |