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| 1 | Exploiting the diversity of tomato:the development of a phenotypically and genetically detailed germplasm collection显示文摘A collection of 163 accessions,including Solanum pimpinellifolium,Solanum lycopersicum var.cerasiforme and Solanum lycopersicum var.lycopersicum,was selected to represent the genetic and morphological variability of tomato at its centers of origin and domestication:Andean regions of Peru and Ecuador and Mesoamerica.The collection is enriched with S.lycopersicum var.cerasiforme from the Amazonian region that has not been analyzed previously nor used extensively.The collection has been morphologically characterized showing diversity for fruit,flower and vegetative traits.Their genomes were sequenced in the Varitome project and are publicly available(solgenomics.net/projects/varitome).The identified SNPs have been annotated with respect to their impact and a total number of 37,974 out of 19,364,146 SNPs have been described as high impact by the SnpEeff analysis.GWAS has shown associations for different traits,demonstrating the potential of this collection for this kind of analysis.We have not only identified known QTLs and genes,but also new regions associated with traits such as fruit color,number of flowers per inflorescence or inflorescence architecture.To speed up and facilitate the use of this information,F2 populations were constructed by crossing the whole collection with three different parents.This F2 collection is useful for testing SNPs identified by GWAs,selection sweeps or any other candidate gene.All data is available on Solanaceae Genomics Network and the accession and F2 seeds are freely available at COMAV and at TGRC genebanks.All these resources together make this collection a good candidate for genetic studies. | Estefanía Mata-Nicolás Javier Montero-Pau Esther Gimeno-Paez Víctor Garcia-Carpintero Peio Ziarsolo Naama Menda Lukas A.Mueller JoséBlanca Joaquín Cañizares Esther van der Knaap María JoséDíez | 2020 | Horticulture Research2020，7，1： | 2 |
| 2 | Mecamylamine modifies the pharmacokinetics and reinforcing effects of alcohol显示文摘 | Blomqvist O Hernandez- Avila CA Van KJ | 2002 | Alcohol Clin Exp Res2002，26，： | 1 |
| 3 | Skin-derived aeroallergen-specific T-cell clones of Th2 phenotype in patients with atopic dermatitis显示文摘 | Bruijnzeel-Koomen CA Kalthoff FS | 1992 | J Allergy Clin Immunol1992，90，： | 1 |
| 4 | Acute renal insufficiency and renal replacement therapy after pediatric cardiopulmonary bypass surgery显示文摘 | Kist van Holthe tot Echten JE Goedvolk CA Doornaar MB | 2001 | Pediatr Cardiol2001，22，： | 1 |
| 5 | Early on-treatment prediction of response to peginterferon alfa-2a for HBeAg-negative chronic hepatitisB using HBsAg and HBV DNA levels 显示文摘 | Rijckborst V Hansen BE Cakaloglu Y Ferenci P Tabak F Akdogan M Simon K Akarca US Flisiak R Verhey E Van Vuuren AJ Boucher CA ter Borg MJ Janssen HL | 2010 | Hepatology2010，52，2： | 1 |
| 6 | Endoscopic ligation of the sphenopalatine artery for refractory posterior epistaxis 显示文摘 | Wormald PJ Wee DT van Hasselt CA | 2000 | Am J Rhinol2000，14，4： | 1 |
| 7 | Feasibility and effects of the semirecumbent posi- tion to prevent ventilator-associated pneumonia: A randomizedstudy显示文摘 | Van Nieuwenhoven CA Vandenbroucke-Grauls C Van Tiel FA | 2006 | Crit Care Med2006，34，2： | 1 |
| 8 | Corona viruses as vectors: position dependence of foreign gene expression显示文摘 | de Haan CA van Genne L Stoop IN | 2003 | J Viral2003，77，11： | 1 |
| 9 | Riskbased selection from the general population in a screening trial:Selection criteria,recruitment and power for the Dutch-Belgian randomised lung cancer Multi-slice CT screening trial (NELSON)显示文摘 | Van Iersel CA De Koning HJ Draisma G | 2007 | Int J Cancer2007，120，： | 1 |
| 10 | Effect of culture conditions on endothelial cell growth and responsiveness显示文摘 | Relou IA Damen CA Van der Schaft DW | 1998 | Tissue Cell1998，30，5： | 1 |
| 11 | High - resol u?tion spiral computed tomography coronary angiography in patients referred for diagnostic conventional coronary angiography显示文摘 | Mollet NR Cademartiri F van Mieg hem CA | 2005 | Cir?culation2005，112，15： | 1 |
| 12 | Preoperative computed tomography coronary angiography to detect significant coronary artery disease in patients referred for cardiac valve surgery显示文摘 | Meijboom WB Meijs MR van Mieghem CA | 2006 | Journal of the hmerican College of Cardiology2006，48，： | 1 |
| 13 | FDG-PETand detection of distant metastases and simultaneous tumors inhead and neck squamous cell carcinoma : a comparison withchest radiography and chest CT显示文摘 | Krabbe CA Pruim J van der Laan BFAM | 2009 | Oral oncology2009，45，3： | 1 |
| 14 | A new method for detection of delirium 显示文摘 | Inouye SK van Dyck CH Alessi CA et aL Clarifying confusion: The Confusion Assessment Method | 1990 | Ann Intern Med1990，113，12： | 1 |
| 15 | Characterization of two bacteriocins produced by Pediococcus acidilactici isolated from 'Alheira', a fermented sausage traditionally produced in Portugal显示文摘 | Albano H Todorov SD van Reenen CA | 2007 | Int J Food Microbiol2007，116，2： | 1 |
| 16 | Percutaneous therapy of bifurcation lesions with drug-eluting stent implantation:the Culotte technique revisited显示文摘 | Hoye A van Mieghem CA Ong AT | 2005 | Int J Cardiovasc Intervent2005，7，1： | 1 |
| 17 | Short-and long-term clinical outcome after drug-eluting stent implantation for the percutaneous treatment of left main coronary artery disease:Insights from the rapamycin-eluting and taxus stent evaluated at rotterdam cardiology hospital registries (RESEARCH and T-SEARCH)显示文摘 | Valgimigli M van Mieghem CA Ong AT | 2005 | Circulation2005，111，： | 1 |
| 18 | Risk-based selection from the general population in a screening trial: Selection criteria, recruitment and power for the Dutch-Belgian randomised lung cancer multi-slice CT screening trial (NELSON) 显示文摘 | van Iersel CA de Koning HJ Draisma G | 2007 | Int J Cancer2007，120，4： | 1 |
| 19 | Pre-operative computed tomography coronary angiography to detect significant coronary artey disease in patients referred for cardiac valve surgery显示文摘 | Meijboom WB Mollet NR Van Mieghem CA | 2006 | J Am Coil Cardiol2006，48，8： | 1 |
| 20 | LEADS: an interactive research oriented ECG/VCG a- nalysis system 显示文摘 | Draisma HHM Swenne CA van de Vooren H | 2005 | Comput Cardiol2005，32，： | 1 |
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