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100篇 您的检索式：作者名="Vertino"

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	题名	作者	年代	出处	被引量
1	Dysregulation of mTOR activity through LKB1 inactivation显示文摘Mammalian target of rapamycin (mTOR) is aberrantly activated in many cancer types, and two rapamycin derivatives are currently approved by the Food and Drug Administration (FDA) of the United States for treating renal cell carcinoma. Mechanistically, mTOR is hyperactivated in human cancers either due to the genetic activation of its upstream activating signaling pathways or the genetic inactivation of its negative regulators. The tumor suppressor liver kinase B1 (LKB1), also known as serine/threonine kinase 11 (STK11), is involved in cell polarity, cell detachment and adhesion, tumor metastasis, and energetic stress response. A key role of LKB1 is to negatively regulate the activity of mTOR complex 1 (mTORC1). This review summarizes the molecular basis of this negative interaction and recent research progress in this area.	Wei Zhou Adam I. M arcus Paula M. Vertino	2013	Chinese Journal of Cancer2013，32，8：	4
2	Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways 显示文摘	Sharma D Saxena NK Vertino PM	2006	Endocr Relat Cancer2006，13，2：	1
3	TMSI/ASC:the cancer connection显示文摘	McConnell B B Vertino P M	2004	Apoptosis2004，9，1：	1
4	Cancer DNA methylation: molecular mechanisms and clinical implications显示文摘	McCabe M T Brandes J C Vertino P M	2009	Clin Cancer Res2009，15，12：	1
5	Wnt10b deficiency promotes coexpression ofmyogenic and adipogenic programs in myoblasts显示文摘	Vertino A M Taylor-Jones J M Longo K A	2005	Mol Biol Cell2005，16，4：	1
6	Cancer DNA methylation: molecular mechanisms and clinical implications 显示文摘	MCCABE M T BRANDES J C VERTINO P M	2009	Clin Cancer Res2009，15，12：	1
7	Leptin promotes the prolifera?tive responseand invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways显示文摘	Sharm D Saxena NK Vertino PM	2006	Endocr Relat Cancer2006，13，2：	1
8	Dual role of TMSI/ASC in death receptor signaling显示文摘	Parsons MJ Vertino PM	2006	Oncogene2006，25，52：	1
9	TMSI/ASG:the cenner connection显示文摘	Mc Connell BB Vertino PM	2004	Apoptosis2004，，：	1
10	TMS1/ASC:the cancer connection显示文摘	McCormell B B Vertino P M	2004	Apoptosis2004，9，1：	1
11	Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain protein TMS1显示文摘	McConnell BB Vertino PM	2000	Cancer Res2000，60，：	1
12	Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain protein TMS1显示文摘	McConnell B B Vertino P M	2000	Cancer Res2000，60，22：	1
13	Wnt10b deficiency promotes coexpression of myogenic and adipagenic programs in myoblasts显示文摘	Vertino A M Taylor-Jones J M Longo K A	2005	Mol Biol Cell2005，16，4：	1
14	Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts显示文摘	Vertino AM Taylor-Jones JM Longo KA	2005	Mol Biol Cell2005，16，4：	1
15	Cancer DNA methylation: molecular mechanisms and clinical implications显示文摘	MCCABE M T BRANDES J C VERTINO P M	2009	Clin Cancer Res2009，15，12：	1
16	Leptin promotes the proliferative response and invasiveness in human endome-trial cancer cells by activating multiple signal-transduction pathways显示文摘	Sharma D Sanena NK Vertino PM	2006	Endocr Relat Cancer2006，13，2：	1
17	Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways 显示文摘	Sharma D Saxena NK Vertino PM	2006	Endocr Relat Cancer2006，13，2：	1
18	leptin-indueed growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3 显示文摘	Saxena NK Vertino PM Anania FA	2007	J Biol Chem2007，282，13：	1
19	DNMT1 is a component of a muhiprotein DNA replication complex显示文摘	VERTINO P M SEKOWSKI J A COLL J M	2002	Cell Cycle2002，1，6：	1
20	Role of TMSI/ASC in death receptor signaling显示文摘	Parsons M J Vertino PM Dual	2006	Oncogene2006，25，69：	1

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