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| 1 | Intralesional steroid is beneficial in benign refractory esophageal strictures:A meta-analysis显示文摘AIM To analyze the effect of intralesional steroid injections in addition to endoscopic dilation of benign refractory esophageal strictures.METHODS A comprehensive search was performed in three databases from inception to 10 April 2017 to identify trials, comparing the efficacy of endoscopic dilation to dilation combined with intralesional steroid injections. Following the data extraction, meta-analytical calculations were performed on measures of outcome by the randomeffects method of Der Simonian and Laird. Heterogeneity of the studies was tested by Cochrane's Q and I^2 statistics. Risk of quality and bias was assessed by the Newcastle Ottawa Scale and JADAD assessment tools.RESULTS Eleven articles were identified suitable for analyses, involving 343 patients, 235 cases and 229 controls in total. Four studies used crossover design with 121 subjects enrolled. The periodic dilation index(PDI) was comparable in 4 studies, where the pooled result showed a significant improvement of PDI in the steroid group(MD:-1.12 dilation/month, 95% CI:-1.99 to -0.25 P = 0.012; I^2 = 74.4%). The total number of repeat dilations(TNRD) was comparable in 5 studies and showed a non-significant decrease(MD:-1.17, 95%CI:-0.24-0.05, P = 0.057; I^2 = 0), while the dysphagia score(DS) was comparable in 5 studies and did not improve(SMD: 0.35, 95%CI:-0.38, 1.08, P = 0.351; I^2 = 83.98%) after intralesional steroid injection.CONCLUSION Intralesional steroid injection increases the time between endoscopic dilations of benign refractory esophageal strictures. However, its potential role needs further research. | László Szapáry Benedek Tinusz Nelli Farkas Katalin Márta Lajos Szakó Agnes Meczker Roland Hágendorn Judit Bajor Aron Vincze Zoltan Gyongyi Alexandra Mikó Dezso Csupor Péter Hegyi Balint Eross | 2018 | World Journal of Gastroenterology2018，24，21： | 7 |
| 2 | Chronic kidney disease severely deteriorates the outcome of gastrointestinal bleeding: A meta-analysis显示文摘AIM To understand the influence of chronic kidney disease(CKD) on mortality, need for transfusion and rebleeding in gastrointestinal(GI) bleeding patients.METHODS A systematic search was conducted in three databases for studies on GI bleeding patients with CKD or endstage renal disease(ESRD) with data on outcomes of mortality, transfusion requirement, rebleeding rate and length of hospitalization(LOH). Calculations were performed with Comprehensive Meta-Analysis software using the random effects model. Heterogeneity was tested by using Cochrane's Q and I2 statistics. Mean difference(MD) and OR(odds ratio) were calculated.RESULTS1063 articles(EMBASE: 589; PubM ed: 459; Cochrane: 15) were found in total. 5 retrospective articles and 1 prospective study were available for analysis. These 6 articles contained data on 406035 patients, of whom 51315 had impaired renal function. The analysis showed a higher mortality in the CKD group(OR = 1.786, 95%CI: 1.689-1.888, P < 0.001) and the ESRD group(OR = 2.530, 95%CI: 1.386-4.616, P = 0.002), and a rebleeding rate(OR = 2.510, 95%CI: 1.521-4.144, P < 0.001) in patients with impaired renal function. CKD patients required more unit red blood cell transfusion(MD = 1.863, 95%CI: 0.812-2.915, P < 0.001) and spent more time in hospital(MD = 13.245, 95%CI: 6.886-19.623, P < 0.001) than the controls.CONCLUSION ESRD increases mortality, need for transfusion, rebleeding rate and LOH among GI bleeding patients. Prospective patient registries and observational clinical trials are crucially needed. | Roland Hágendorn Nelli Farkas Aron Vincze Zoltán Gyongyi Dezso Csupor Judit Bajor Bálint Eross Péter Csécsei Andrea Vasas Zsolt Szakács László Szapáry Péter Hegyi Alexandra Mikó | 2017 | World Journal of Gastroenterology2017，23，47： | 3 |
| 3 | Investigation of the gene locus in autosomal polycystic kidney disease in a 21 year old female patient with congenital hepatic fibrosis and polycystic liver显示文摘 | Kosztolanyi S Gasztonyi B Vincze A | 2002 | Orv Hetil2002，143，46： | 2 |
| 4 | Interaction of TPPP/p25 pro-tein with glyceraldehyde-3-phosphate dehydrogenase and their co-localization in Lewy bodies显示文摘 | Olah J Tokesi N Vincze O | 2006 | FEBS Lett2006，580，： | 1 |
| 5 | Application of nanofiltration for coffee extract concentration显示文摘 | Ivetta Vincze Gyula Vatai | 2004 | Desalination2004，162，13： | 1 |
| 6 | New therapeutic approaches for polymyositis and dermatomyositis显示文摘 | Danko K Vincze M | 2011 | Orv Hetil2011，152，39： | 1 |
| 7 | An unusual association:anti-Jol and anti-SRP antibodies in the serum of a patient with polymyositis显示文摘 | Vincze M Molnár PA Tumpek J | 2010 | Clin Rheumatol2010，29，： | 1 |
| 8 | The BioScope Corpus:Biomedical Texts Annotated for Uncertainty,Negation and their Scopes显示文摘 | Vincze V Szarvas G Farkas R | 2008 | Journal of BMC Bioinformatics2008，9，11： | 1 |
| 9 | MRSA variant in com- panion animals 显示文摘 | Walther B Wieler L H Vincze S | 2012 | Emerg Infect Dis2012，18，： | 1 |
| 10 | Integrated Vision System for the Semantic Interpretation of Activities Where aPerson Handles Objects显示文摘 | Vincze M Zillich M Ponweiser W | 2009 | Computer Vision and Image Un- derstanding2009，113，6： | 1 |
| 11 | A laser tracking system to measure position and orientation of robot end effectors under motion 显示文摘 | Vincze M Prerminger J P Gander H | 1994 | The International Journal of Robotics Research1994，13，4： | 1 |
| 12 | Peripheral CD4+ cell prevalence and pleuropulmonary manifestations in systemic lupus erythematosus patients显示文摘 | Vincze K Kovats Z Cseh A | 2014 | Respir Med2014，954，14： | 1 |
| 13 | Interpretation of capillary generated spatial and angular distributions of X-rays:theoretical modeling and experimental verification using the European synchrotron radiation facility optical beam line显示文摘 | Vincze L Janssens K Adams F | 1998 | Rev Sci Instum1998，69，： | 1 |
| 14 | Distribution of mRNAs enco- ding transforming growth factors-β1, -2, and -3 in the intact rat brain and after experimentally induced focal ischemia 显示文摘 | Vincze C Pal G Wappler EA | 2010 | J Comp Neurol2010，518，18： | 1 |
| 15 | Determination of the chemical composition of acorn (Quercus branti), Pistacia atlantica and Pistacia Khinjk seeds as non-conventional feedstuffs 显示文摘 | Saffarzadeh A Vincze L Csapo J | 1999 | Acta Agr Kapos1999，3，3： | 1 |
| 16 | Growth factors in ulcer healing: lessions from recent studies 显示文摘 | Szabo S Vincze A | 2000 | J Physiol Paris2000，92，4： | 1 |
| 17 | Determination of tropane alkaloids atropine and scopolamlne by liquid chromatosraphy- mass spectrometry in plant organs of Datura species 显示文摘 | Silvia Jakabovd Lajos Vincze gnes Farkas | 2012 | Journal of Chromatography A2012，1232，： | 1 |
| 18 | Increased sensitivity for determination of polycyclic aromatic hydrocarbon-DNA adducts in human DNA samples by dissociation-enhanced lanthanidefluoroimmunoassay(DELFIA)显示文摘 | Schoket B Doty WA Vincze I Strickland PT Ferri GM Assennato G | | Cancer0，，： | 1 |
| 19 | Growth factors in ulcer healing:lessons from recent studies显示文摘 | Szabo S Vincze A | 2000 | J Physiol Paris2000，94，： | 1 |
| 20 | Growth factors in ulcer healing:lessons from recent studies 显示文摘 | Szabo S Vincze A | 2000 | J Physiol Paris2000，94，： | 1 |
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