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| 1 | High-intensity focused ultrasound ablation:An effective bridging therapy for hepatocellular carcinoma patients显示文摘AIM:To analyze whether high-intensity focused ultrasound(HIFU) ablation is an effective bridging therapy for patients with hepatocellular carcinoma(HCC).METHODS:From January 2007 to December 2010,49 consecutive HCC patients were listed for liver transplantation(UCSF criteria).The median waiting time for transplantation was 9.5 mo.Twenty-nine patients received transarterial chemoembolization(TACE) as a bringing therapy and 16 patients received no treatment before transplantation.Five patients received HIFU ablation as a bridging therapy.Another five patients with the same tumor staging(within the UCSF criteria) who received HIFU ablation but not on the transplant list were included for comparison.Patients were comparable in terms of Child-Pugh and model for end-stage liver disease scores,tumor size and number,and cause of cirrhosis.RESULTS:The HIFU group and TACE group showed no difference in terms of tumor size and tumor number.One patient in the HIFU group and no patient in the TACE group had gross ascites.The median hospital stay was 1 d(range,1-21 d) in the TACE group and two days(range,1-9 d) in the HIFU group(P < 0.000).No HIFU-related complication occurred.In the HIFU group,nine patients(90%) had complete response and one patient(10%) had partial response to the treatment.In the TACE group,only one patient(3%) had response to the treatment while 14 patients(48%) had stable disease and 14 patients(48%) had progressive disease(P = 0.00).Seven patients in the TACE group and no patient in the HIFU group dropped out from the transplant waiting list(P = 0.559).CONCLUSION:HIFU ablation is safe and effective in the treatment of HCC for patients with advanced cirrhosis.It may reduce the drop-out rate of liver transplant candidate. | Tan To Cheung Sheung Tat Fan See Ching Chan Kenneth SH Chok Ferdinand SK Chu Caroline R Jenkins Regina CL Lo James YY Fung Albert CY Chan William W Sharr Simon HY Tsang Wing Chiu Dai Ronnie TP Poon Chung Mau Lo | 2013 | World Journal of Gastroenterology2013，19，20： | 23 |
| 2 | 完全叠接管节点在低周循环载荷下的破坏模式研究显示文摘采用实验和数值模拟方法研究了一种新型海洋平台管节点在地震载荷下的响应和破坏情况。采用拟静态循环加载模拟地震载荷 ,对真实尺寸的试件进行实验 ,研究局部屈曲和裂纹等对管接点抗震性能的影响。能量分析表明 ,发生在斜支管中的局部屈曲消耗了大部分输入能量。与现在使用的N型管节点相比 ,该新型管节点有较好的抗震性能。采用有限元数值模拟方法分析比较了不同尺寸配置下 。 | 秦飞 GHO W M FUNG TC Soh C K | 2002 | 海洋工程2002，20，1： | 7 |
| 3 | Practice of breast self-examination among high risk Chinese women in Hong Kong显示文摘The incidence of breast cancer in Hong Kong is increasing and breast self examination (BSE) as a screening tool is becoming more popular, especially among first degree relatives (FDR) of breast cancer victims BSE may be more applicable to Chinese women as their breast size is smaller This study explores the BSE practice in this group of women Methods A cross sectional study was conducted by sending questionnaires to 330 FDR of breast cancer patients treated in the Department of Surgery, University of Hong Kong BSE behavior was studied with respect to its frequency, awareness, completeness and confidence of practice Results 110 subjects returned the questionnaires with a response rate of 33% The mean age of the respondent was 37 years Only 57 women (52%) were practicers The practicers have a stronger BSE awareness ( P <0 01) and a lower mean score on thought barriers ( P =0 002) than the non practicers 40% of the practicers gain their BSE knowledge through clinicians and their mean period of practice was 3 2 years 68% of the practicers performed BSE completely The overall confidence rate was 35%, but the rate was 43% among those who performed complete BSE Thirteen factors possibly related to the completeness and rate of confidence of BSE examination were studied The only factor that significantly determined completeness was the time spent for each examination ( P =0 002) The complete practicers required a longer time than the incomplete practicers (6 60 and 2 96?min, respectively) Women with a stronger BSE intention ( P =0 001) and a lower mean score on thought barriers ( P =0 001) performed the examination confidently Conclusions Slightly over half of the FDR practice BSE The majority perform a complete BSE but they are not confident in finding abnormalities Women spending more time on BSE are associated with a higher rate of completeness However, only those with a stronger BSE intention and lesser thought barriers are more confident in their | Kelvin K C Ng, Fung S Y and Louis W C Chow DepartmentofSurgery (NgKKCandChowLWC)&NursingStudies (FungSY ) ,TheUniversityofHongKong ,QueenMaryHospital ,HongKong ,China | 2000 | Chinese Medical Journal2000，，12： | 4 |
| 4 | Contribution of vacuum field to angular deviation of light path and radar echo delay 显示文摘 | Lu H Q Fung P C W | 1997 | Astrophysics and Space Science1997，253，： | 2 |
| 5 | Antioxidatiou of human low density lipoprotein by unconjugated and conjugated bilirubins 显示文摘 | Wn T W Fung K P Wn J | 1996 | Biochem Pharmacol1996，51，： | 1 |
| 6 | Non-structural Fuzzy Decision Support System for Evaluation of Construction Safety Management System显示文摘 | Tam C M Tong Thomas K L Chiu Gerald C W Fung Ivan W H | 2002 | International Journal of Project Management2002，，20： | 1 |
| 7 | A novel tool to assess systolic asynchrony and identify responders of cardiac resynchronization therapy by tissue synchronization imaging 显示文摘 | YU C M ZHANG Q FUNG J W | 2005 | J Am Coll Cardiol2005，45，5： | 1 |
| 8 | Micelles and aggregates of fluorinated surfactants 显示文摘 | GUO W BROWN T FUNG B M | 1991 | J Phys Chem1991，95，： | 1 |
| 9 | Higher-order multivariate Markov chains and their applications显示文摘 | Ching W K Ng M K Fung E S | 2008 | Linear Algebra and its Applications2008，428，2： | 1 |
| 10 | Classifying intertrochanteric fractures of the proximal femur: Does experience matter 显示文摘 | Fung W Jonsson A Buhren V | 2007 | Med Princ Pract2007，16，3： | 1 |
| 11 | Optimizing Timetable Synchronization for Rail Mass Transit 显示文摘 | Wong R C W Yuen T W Y Fung K W | 2008 | Transportation Sci- ence2008，42，1： | 1 |
| 12 | NMR study of cyclodextrin inclusion of fluorocarbon surfactants in solution显示文摘 | GUO W FUNG B M CHRISTIAN S D | 1992 | Langmuir1992，8，2： | 1 |
| 13 | Asset pricing in segmented capital markets: Preliminary evidence from China-domiciled companies 显示文摘 | Poon W P H Firth M Fung H | 1998 | Pacific-Basin Finance Journal1998，6，3： | 1 |
| 14 | Cellular and molecular mechanisms of pulmonary vascular remodeling:role in the development of pulmonary hypertension显示文摘 | MANDEGAR M FUNG Y C HUANG W | 2004 | Microvasc Res2004，68，2： | 1 |
| 15 | Psychometric properties of the Chinese version of the mini-mental adjustment to cancer (MINI-MAC) scale显示文摘 | Ho S M Y Kam Fung W Chan C L W | 2003 | Psycho Oncol2003，12，6： | 1 |
| 16 | Cellular and molecular mechanisms of pulmonary vascular remode- ling:role in the development of pulmonary hyperten sion显示文摘 | Mandegar M Fung Y C Huang W | 2004 | Microvasc Res2004，68，2： | 1 |
| 17 | Higher-order multivariate Markov chains and their applications显示文摘 | Ching W K Ng M K Fung E S | 2008 | Linear Algebra and its Applica- tions2008，428，2： | 1 |
| 18 | Development of a colloidal gold strip for rapid detection of echratoxin A with mimotope peptide显示文摘 | LAI W H FUNG D Y C XU Y | 2009 | Food con- trol2009，20，9： | 1 |
| 19 | Particle release from respirators, part I: detennination of the effect of part -icle size, drop height, and load显示文摘 | BIRKNER J S FUNG D HINDS W C | 2011 | J Occup Environ Hyg2011，8，1： | 1 |
| 20 | Clinical versus echacardiographic parameters to assess response to cardiac resynehronization therapy显示文摘 | Bleeker G B Bax J J Fung J W | 2006 | Am J Cardiol2006，97，2： | 1 |
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