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288篇 您的检索式:作者名="WIJNEN"
    题名 作者 年代 出处 被引量
1Four cancer cases after esophageal atresia repair: Time to start screening the upper gastrointestinal tract显示文摘Esophageal atresia(EA) is one of the most common congenital digestive malformations and requires surgical correction early in life. Dedicated centers have reported survival rates up to 95%. The most frequent comorbidities after EA repair are dysphagia(72%) and gastroesophageal reflux(GER)(67%). Chronic GER after EA repair might lead to mucosal damage, esophageal stricturing, Barrett's esophagus and eventually esophageal adenocarcinoma. Several long-term follow-up studies found an increased risk of Barrett's esophagus and esophageal carcinoma in EA patients, both at a relatively young age. Given these findings, the recent ESPGHAN-NASPGHAN guideline recommends routine endoscopy in adults born with EA. We report a series of four EA patients who developed a carcinoma of the gastrointestinal tract: three esophageal carcinoma and one colorectal carcinoma in a colonic interposition. These cases emphasize the importance of lifelong screening of the upper gastrointestinal tract in EA patients.Floor WT Vergouwe Madeleine Gottrand Bas PL Wijnhoven Hanneke IJsselstijn Guillaume Piessen Marco J Bruno René MH Wijnen Manon CW Spaander 2018World Journal of Gastroenterology2018,24,9:3
2癫痫患者治疗经济评价的系统回顾显示文摘越来越多的治疗方案和与癫痫相关的高成本促进了癫痫疾病经济评价的发展。因此,检查这些经济评价的可用性、质量并找出潜在的研究差距非常重要。除了研究抗癫痫药物(AEDs)和非药物(例如癫痫手术、生酮饮食、迷走神经刺激)治疗外,本综述还考察了所有经济评价的方法学质量。我们使用MEDLINE,EMBASE,NHS经济评价数据库(NHS EED),Econlit,Web of Science和CEA Registry进行了文献检索。此外,还使用了Cochrane评价,Cochrane DARE和Cochrane健康技术评价数据库。为了识别相关研究,我们设计了将预定义的临床检索策略与检索过滤器结合的模式以识别健康经济学相关的研究。以下主题都使用了特别设计的特定检索策略:(1) AEDs;(2)认知缺陷患者;(3)老年患者;(4)癫痫手术;(5)生酮饮食;(6)迷走神经刺激;(7)治疗(非)惊厥性癫痫持续状态。本综述共纳入40篇文献,其中29篇(73%)为有关药物干预的文章。以'健康经济学标准共识'(Consensus health economic criteria,CHEC)评价,所有文章的平均质量评分为81.8%,最低质量评分为21.05%,有五项研究评分为100%。使用综合健康经济评价报告标准(Consolidated health economic evaluation reporting standards,CHEERS),平均质量得分为77.0%,最低为22.7%,有四项研究评定为100%。所有纳入的文章在方法学上存在很大的差异,这阻碍了将信息进行有意义地合并。总的来说,方法学质量是可以接受的,尽管一些研究质量明显比其他研究差。研究之间的异质性强调需要确定一个参考案例(例如应该如何进行癫痫内的经济评价),并就什么为'最佳治疗标准'达成共识。Wijnen BFM van Mastrigt GAPG Evers SMAA 李思思 高慧 慕洁 2018癫痫杂志2018,4,6:2
3Molecular characterization of the spectrum of genomic deletions in the mismatch repair genes MSH2, MLH1, MSH6 and PMS2 responsible for hereditary nonpolyposis colorectal cancer ( HNPCC ) 显示文摘Heleen van der Klift Juul Wijnen Anja Wagner 2005Genes Chromosomes and Cancer2005,44,2:1
4Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites显示文摘Zaidi SK Sullivan AJ van Wijnen AJ 2002Proc Natl Acad Sci USA2002,99,12:1
5Development of a runway allocation optimisation model for airport strategic planning显示文摘Heblij S J Wijnen R A A 2008Transportation Planning and Technology2008,31,2:1
6Security features of SNMPv3显示文摘Blumenthal U Wijnen B 1997The Simple Times (S0264-1039)1997,5,1:1
7Mismatch negativity predicts recovery from the vegetative state显示文摘Wijnen VJ van Boxtel GJ Eilander HJ 2007Clin Neurophysiol2007,118,3:1
8MieroRNA control of bone formation and homeostasis显示文摘Lian JB Stein GS van Wijnen A J 2012Nat Rev Endocrinol2012,8,4:1
9MicroRNA con- trol of bone formation and homeostasis 显示文摘Lian JB Stein GS van Wijnen AJ 2012Nat Rev En- docrinol2012,8,4:1
10Colors and pterin pigmentation of pierid butterfly wings显示文摘WIJNEN B LEERTOUWER H L STAVENGA D G 2007J Insect Physiol2007,53,12:1
11Integration of Runx and Smad regulatory signals at transcrip tionally active subnuclear sites显示文摘Zaidi SK Sullivan AJ van Wijnen AJ 2002Proc Natl Acad Sci USA2002,99,:1
12Nuclear structure-gene expression interrelationships: implications for aberrant gene expression in cancer显示文摘Stein GS Montecino M Wijnen A J 2000Cancer Res2000,60,8:1
13Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites 显示文摘Zaidi SK Sullivon AJ Wijnen AJV 2002Proc Natl Acad Sci USA2002,99,12:1
14Impact of aquality improvement programme based on vascular access flowmonitoring on costs,access occlusion and access failure显示文摘WIJNEN E PLANKEN N KEUTER X 2006Nephrol Dial Transplant2006,21,12:1
15Detection of a proliferation specific gene during development of the osteoblast phenotype by mRNA differential display显示文摘Ryoo H M van Wijnen A J Stein J L 1997J Cell Biochem1997,64,1:1
16Interferon regulatory factors: growth control and histone gene regulation-it' s not just interferon anymore 显示文摘Patricia S Vaughan A J Wijnen J L 1997Mol Med1997,75,:1
17Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression显示文摘Stein GS Lian JB van Wijnen AJ 2004Oncogene2004,23,24:1
18Impact of a quality improvement programme based on vascular access flow monitoring on costs, access occlusion and access failure显示文摘Edwin Wijnen Niis Planken Xavier Keuter 2006Nephrol Dia Transplant2006,21,:1
19Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites显示文摘Zaidi SK Sullivan AJ van Wijnen AJ 2002Proc Natl Acad Sci USA2002,99,:1
20Depressive effect ofan antidepressant: therapeutic failure of venlafaxine in a caselacking CYP2D6 activity 显示文摘Wijnen PA Limantoro I Drent M 2009Ann Clin Biochem2009,46,6:1
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