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| 1 | 世界胃肠病学组织全球指南——发展中国家幽门螺杆菌感染显示文摘世界上有一半人口感染幽门螺杆菌(H.pylori),其感染率因地理位置、种族、年龄和社会经济状况不同而存在很大差异.在发展中国家较高.发达国家较低。但总体而言,近年世界许多地区的H.pylori感染率均呈下降趋势。 | Hunt RH Xiao SD Megraud F Leon-Barua R Bazzoli F van der Merwe S Vaz Coelho LG Fock M Fedail S Cohen H Malfertheiner P Vakil N Hamid S Goh KL Wong BCY Krabshuis J Le Mair A 杜颖 戴宁 | 2011 | 胃肠病学2011，16，7： | 27 |
| 2 | Role of LPS/CD14/TLR4-mediated inflammation in necrotizing enterocolitis:Pathogenesis and therapeutic implications显示文摘AIM:To establish the roles of lipopolysaccharide (LPS)/CD14/toll-like receptor 4 (TLR4)-mediated inflammation in a rat model of human necrotizing enterocolitis (NEC).METHODS: Six pairs of intestinal samples from human NEC were collected before and after recovery for histological and molecular analysis of inflammatory cytokines and signaling components. In the rat NEC model, we isolated 10-cm jejunum segments and divided them into six groups (n=6) for sham operation, treatment with LPS, bowel distension, combined bowel distension and LPS stimulation, and two therapeutic groups. The potential eff icacy of a recombinant CD18 peptide and a monoclonal CD14 antibody was evaluated in the latter two groups. The serum and tissue levels of several inflammatory mediators were quantified by real-time polymerase chain reaction, ELISA and immunoblotting.RESULTS: Human acute phase NEC tissues displayed significant increases (P<0.05) in levels of TLR4, CD14, myeloid differentiation protein (MD)-2, tumor necrosis factor (TNF)-α and nuclear factor-κB when compared to those after recovery. The histological and inflammatory picture of human NEC was reproduced in rats that were treated with combined bowel distension and LPS, but not in the sham-operated and other control rats. Serum levels of interleukin-6 and TNF-α were also elevated. The NEC pathology was attenuated by treating the NEC rats with a monoclonal CD14 antibody or an LPS-neutralizing peptide.CONCLUSION:LPS and distension are required to produce the histological and inflammatory features of NEC. A potential treatment option is blocking LPS activation and leukocyte infi ltration. | Kwong L Chan Kwong F Wong John M Luk | 2009 | World Journal of Gastroenterology2009，15，38： | 17 |
| 3 | 残余应力导致三层聚烯烃管道防腐层剥离与开裂显示文摘这是美国运输部发起的研究项目,一个管道防腐层专家团队参与了本研究项目,评价了三层聚烯烃管道外防腐涂层(3LPO)的完整性。研究表明,三层聚烯烃管道外防腐涂层(3LPO)存在剥离和面层开裂两大完整性问题。过去几年里,据文献报道,三层聚烯烃管道外防腐涂层(3LPO)的熔结环氧粉末(FBE)底漆与钢管界面上发生多起防腐层剥离事故,以及聚丙烯(PP)面层发生开裂事故。这些防腐层事故引起人们对使用三层聚烯烃管道外防腐涂层(3LPO)的关注。一般来讲,三层聚烯烃管道外防腐涂层(3LPO)采用比较厚的聚烯烃面层增强防腐层抗机械损伤和防止水渗透的能力。但是,聚烯烃的热膨胀系数比钢材高得多,结果在防腐层系统里产生比较高的残余热应力。因为残余应力高,造成防腐层剥离,尤其在管端截短防腐层和任何防腐层的边上,因为这些是高应力集中部位。特别是假如钢管表面预处理不当,就无法保证防腐层持久达到很强的粘合强度。如果熔结环氧粉末(FBE)底漆配方选择不当,发生热氧化降解,也导致防腐层过早失效。如果使用温度很高,聚丙烯也会因为热氧化降解而变脆。在残余应力下,这样脆性的聚丙烯面层就会开裂。本文分析了三层聚烯烃管道外防腐涂层(3LPO)中的残余应力,并且探讨了残余应力对三层聚烯烃管道外防腐涂层(3LPO)剥离和聚丙烯(PP)面层开裂机理的影响。 | B.T.A.Cheng S Hung-jue J Han D Wong A Kehr M Mallozzi F Aguirre H Pham W Snider 王向农(译) | 2011 | 防腐保温技术2011，19，3： | 3 |
| 4 | Identification and occurrence of tetrad-forming Alphaproteobacteria in anaerobic-aerobic activated sludge processes 显示文摘 | WONG M T TAN F M NG W J | 2004 | Microbiology2004，150，： | 1 |
| 5 | Real-time PCR for mRNA quantitation 显示文摘 | Wong M L Medrano J F | 2005 | Biological Techniques2005，39，： | 1 |
| 6 | Characteristics, apa tire-forming ability and corrosion resistance of NiTi surface modified by AC anodization 显示文摘 | WONG M H CHENG F T MAN H C | 2007 | Appl Surface Sci2007，253，18： | 1 |
| 7 | An optical bio- sensor for dichlovos using stacked sol - gel films contai- ning acetylcholinesterase and a lipophilic chromoionophore 显示文摘 | Wong F C M Ahmad M Heng L Y | 2006 | Talanta2006，69，4： | 1 |
| 8 | Localization of damage structural connections based on experimental modal and sensitivity analysis显示文摘 | Lain H F Ko J M Wong C W | 1998 | Journal of Sound and Vibration1998，210，1： | 1 |
| 9 | Aluminum and fluoride contents of tea with emphasis on brick tea and their health implications显示文摘 | Wong M H Fung K F Carr H P | 2003 | Toxicol Lett2003，137，： | 1 |
| 10 | Hairy Enhancer of Split-1 (HES-1),a Notchl effector,inhibits the growth of carcinoid tumor cells显示文摘 | Kunnimalaiyaan M Yan S Wong F | 2005 | Surgery2005，138，6： | 1 |
| 11 | A new framework of simultaneous-fauh diagnosis using pairwise probabilistic multi-label classification for time- dependent modes显示文摘 | VONG C M WONG P K IP W F | 2013 | IEEE Transaction on Industrial Electronics2013，60，8： | 1 |
| 12 | Biosorption and bioreduction of Cr(VI) by a microalgal isolate, Chlorella miniata显示文摘 | Han X Wong Y S Wong M H Tam N F Y | 2007 | Journal of Hazardous Materials2007，146，12： | 1 |
| 13 | A novel approach to measure sliplength of thin lubricant films under high pressures 显示文摘 | Guo F Li X M Wong P L | 2012 | Tribology International2012，46，： | 1 |
| 14 | Thermal stress responses in antarctic yeast, glaciozyma antarctica PI12, characterized by real-time quantitative PCR显示文摘 | Boo S Y Wong C M Rodrigues K F | 2013 | Polar Biology2013，36，3： | 1 |
| 15 | Simultaneous escape-routing algorithms for via minimization of high-speed boards显示文摘 | OZDAL M M WONG M D F HONSINGER P S | 2008 | IEEE Transactions on ComputerAided Design of Integrated Circuits and Systems2008，27，1： | 1 |
| 16 | Chromosomal aberrations of primary lung adenocarcinomas in nonsmokers显示文摘 | WONG M P FUNG L F WANG E | 2003 | Cancer2003，97，5： | 1 |
| 17 | Laser oxidation of NiTi for improving corrosion resistance in Hanks' solution 显示文摘 | Wong M H Cheng F T Man H C | 2007 | Materials Letters2007，61，16： | 1 |
| 18 | Relationship of Nurses' Spirituality to Their Understanding and Practice of Spiritual Care显示文摘 | Chung L Y Wong F K Chan M F | 2007 | J Adv Nurs2007，58，2： | 1 |
| 19 | Quantitiation of covalently closed circular hepatitis B virus DNA in chronic hepatitis B patients显示文摘 | Wong D K Yuen M F Tuan H | | 0，，03： | 1 |
| 20 | Recovery of replication competent HIV despite prolonged suppression of plasma viremia显示文摘 | Wong J K Hezareh M Gunthard H F | 1997 | Science1997，278，： | 1 |
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