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| 1 | Impacts of permafrost changes on alpine ecosystem in Qinghai-Tibet Plateau显示文摘Alpine cold ecosystem with permafrost environment is quite sensitive to climatic changes and the changes in permafrost can significantly affect the alpine ecosystem. The vegetation coverage, grassland biomass and soil nutrient and texture are selected to indicate the regime of alpine cold ecosystems in the Qinghai-Tibet Plateau. The interactions between alpine ecosystem and permafrost were investigated with the depth of active layer, permafrost thickness and mean annual ground temperature (MAGTs). Based on the statistics model of GPTR for MAGTs and annual air temperatures, an analysis method was developed to analyze the impacts of permafrost changes on the alpine ecosystems. Under the climate change and human engineering activities, the permafrost change and its impacts on alpine ecosystems in the permafrost region between the Kunlun Mountains and the Tanggula Range of Qinghai-Tibet Plateau are studied in this paper. The results showed that the per- mafrost changes have a different influence on different alpine ecosystems. With the increase in the thickness of active layer, the vegetation cover and biomass of the alpine cold meadow exhibit a significant conic reduction, the soil organic matter content of the alpine cold meadow ecosystem shows an exponential decrease, and the surface soil materials become coarse and gravelly. The alpine cold steppe ecosystem, however, seems to have a relatively weak relation to the permafrost environment. Those relationships resulted in the fact that the distribution area of alpine cold meadow decreased by 7.98% and alpine cold swamp decreased by 28.11% under the permafrost environment degradation during recent 15 years. In the future 50 years the alpine cold meadow ecosystems in different geomorphologic units may have different responses to the changes of the permafrost under different climate warming conditions, among them the alpine cold meadow and swamp ecosystem located in the low mountain and plateau area will have a relatively serious degradation. Furthermore, from the angles of grassland coverage and biological production the variation characteristics of high-cold eco- systems in different representative regions and different geomorphologic units under different climatic conditions were quantitatively assessed. In the future, adopting effective measures to protect permafrost is of vital importance to maintaining the stability of permafrost engineering and alpine cold eco- systems in the plateau. | WANG Genxu1,3 , LI Yuanshou2 , WU Qingbai2 & WANG Yibo3 1. Institute of Mountain Hazards and Environment, Chinese Academy of Sciences, Chengdu 610041, China 2. Cold and Arid Regions Environmental and Engineering Research Institute, Chinese Academy of Sciences, Lanzhou 730000, China 3. Resource and Environment School, Lanzhou University, Lanzhou 730000, China | 2006 | Science China Earth Sciences2006，49，11： | 41 |
| 2 | Alterations in metastatic properties of hepatocellular carcinoma cell following H-ras oncogene transfection显示文摘AIM To demonstrate the relationship betweenH-ras oncogene and hepatocellular carcinoma(HCC) metastasis.METHODS Activated H-ras oncogene wastransfected into SMMC 7721, a cell line derivedfrom human HCC, by calcium phosphatetransfection method. Some metastasis-relatedparameters were detected in vitro, includingadhesion assay, migration assay, expression ofcollagenase ⅣV (c ⅣV ase) and epidermal growthfactor receptor (EGFR).RESULTS The abilities of H-ras-transfected cellclones in adhesion to laminin (LN) or fibronectin(FN), migration, c Ⅳ ase secretion increasedmarkedly, and the expression of EGFR elevatedmoderately. More importantly, these alterationswere consistent positively with the expressionof p21, the protein product of H-ras oncogene.CONCLUSION H-ras oncogene could inducethe metastatic phenotype of HCC cell in vitro toraise its metastatic potential. | Qing Wang~1 Zhi Ying Lin~2 Xiao Li Feng~3 ~1Department of Microbiology,Medical Center of Fudan University.the former Shanghai Medical University,Shanghai 200032,China ~2Liver Cancer Institute,Zhongshan Hospital,Shanghai 200032,China ~3Shanghai Institute of Biochemistry,Academy Sinica,Shanghai 200031,ChinaQing Wang earned master degree from Shanghai Medical University in 1996,now a senior lecturer of microbiology,specialized in the role of oncogcncs on tumor metastasis,having 8 papers published. | 2001 | World Journal of Gastroenterology2001，7，3： | 48 |
| 3 | The deformation pattern and fault rate in the Tianshan Mountains inferred from GPS observations显示文摘Based on GPS measurements conducted from 1992 to 2006, we present the current crustal movement velocity field for approximately 400 sites in the Tianshan Mountains and their adjacent areas, and estimate slip rates on the major faults using a 2-D elastic dislocation model. Our studies show slip rates within the range of 1―4 mm/a on the NW-SE trending strike-slip faults (such as Talas-Fergana fault) in the Tianshan Mountains. We also found the slip rates on the approximately WE-SN trending gently-dipping detachment fault vary from 10―13 mm/a for the southwest Tianshan Mountains to 2―5 mm/a for the eastern Tianshan Mountains, and to 6―12 mm/a for the Kyrgrz Tianshan. The GPS velocity field reveals that the total convergence is not uniformly distributed across the Tianshan Mountains, with 80%―90% of the N-S shortening absorbed along the southern and northern edges, and relatively little deformation accommodated within the interior. This first-order feature of strain pattern is explained best by underthrusting of adjacent blocks beneath the Tianshan Mountains along a basal detachment fault. We found the occurrence of historical M7―8 earthquakes somewhere in the locked ramp that connects the creeping and locking segments of the detachment, thereby resulting in elastic strain concentration and accumulation around it. The elastic strain confined in the upper crustal layer above the detachment ultimately releases through infrequent great earthquakes in the Tianshan Mountains, resulting in considerable folding and faulting at their margins. The Tianshan Mountains propagated outward and rose progressively as a wedge-shaped block. | YANG ShaoMin1,2, LI Jie1,3 & WANG Qi2,1 1 Research Center of Space Science and Technology, China University of Geosciences, Wuhan 430074, China 2 Institute of Seismology, China Earthquake Administration, Wuhan 430071, China 3 Earthquake Administration of Xinjiang Uygur Autonomous Region, Urumqi 830011, China | 2008 | Science China Earth Sciences2008，51，8： | 43 |
| 4 | Characterization for commutators of n-dimensional fractional Hardy operators显示文摘In this paper, it was proved that the commutator Hβ,b generated by an n-dimensional fractional Hardy operator and a locally integrable function b is bounded from Lp1(Rn) to Lp2 (Rn) if and only if b is a C(M)O(Rn) function, where 1/p1 - 1/p2 = β/n, 1 < p1 <∞, 0 ≤β< n. Furthemore,the characterization of Hβ,b on the homogenous Herz space (K)qα,p(Rn) was obtained. | Zun-wei FU~(1,2) Zong-guang LIU~3 Shan-zhen LU~(1+) Hong-bin WANG~3 ~1 School of Mathematical Sciences,Beijing Normal University,Beijing 100875,China ~2 Department of Mathematics,Linyi Normal University,Linyi 276005,China ~3 Department of Mathematics,China University of Mining and Technology (Beijing),Beijing 100083,China | 2007 | Science China Mathematics2007，50，10： | 39 |
| 5 | Interannual variability of Antarctic Oscillation and its influence on East Asian climate during boreal winter and spring显示文摘The interannual variability of Antarctic Oscillation (AAO) and its influence on East Asian climate during both boreal winter and spring are addressed. The results show that the positive AAO anomaly decreases the cold activity over East Asia during both boreal winter and spring. AAO-related barotropic meridional teleconnection from Antarctic to Arctic is found through analysis of mean me- ridional circulations. This meridional teleconnection is remarkable over Eurasia during boreal winter and over the Pacific Ocean during boreal spring. The results also show that zonal mean zonal wind at high latitudes in Southern Hemisphere has well positive correlation with that of Eurasia during boreal winter and has negative correlation with Pacific North American teleconnection (PNA) during boreal spring, which again display the meridional teleconnection. Thus, local meridional teleconnection is a possible linkage for interaction of circulations at mid-high latitudes between both hemispheres. | FAN Ke1,2,3 & WANG Huijun2 1. Nansen-Zhu International Research Center, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, China 2. Department of Atmospheric Science, Yunnan University, Kunming 650091, China 3. Graduate University of the Chinese Academy of Sciences, Beijing 100049, China | 2006 | Science China Earth Sciences2006，49，5： | 36 |
| 6 | Ultrahigh pressure (>7 GPa) gneissic K-feldspar (-bearing) garnet clinopyroxenite in the Altyn Tagh, NW China: Evi- dence from clinopyroxene exsolution in garnet显示文摘The exsolution of clinopyroxene and rutile in coarse-grain garnet is found in the gneissic K-feldspar(-bearing) garnet clinopyroxenite from Yinggelisayi in the Altyn Tagh, NW China. The maximum content of the exsolved clinopyroxene in the garnet is up to >5% by volume. The reconstructed precursor garnet (Grt1) before exsolution has a maximum Si content of 3.061 per formula uint, being of supersilicic or majoritic garnet. The peak-stage metamorphic pressure of >7 GPa is estimated using the geobarometer for volume percentage of exsolved pyroxene in garnet and the Si-(Al+Cr) geobarometer for majoritic garnet, and the temperature of about 1000℃ using the ternary alkali-feldspar geothermometer and the experimental data of ilmen- ite-magnetite solid solution. The protoliths of the rocks are intra-plate basic and intermediate ig- neous rocks, of which the geochemical features indicate that they are probably the products of the evolution of basic magma deriving from the continental lithosphere mantle. The rocks are in outcrops associated with ultrahigh pressure garnet-bearing lherzolite and ultrahigh pressure garnet granitoid gneiss. All of these data suggest that the ultrahigh pressure metamorphic rocks in the Altyn Tagh are the products of deep-subduction of the continental crust, and such deep- subduction probably reaches to >200 km in depth. This may provide new evidence for further discussion of the dynamic mechanism of the formation and evolvement of the Altyn Tagh and the other collision orogenic belts in western China. | LIU Liang1,3, CHEN Danling1, ZHANG Anda1, SUN Yong1, WANG Yan1, YANG Jiaxi1,2 & LUO Jinhai1 1. Key Laboratory of Continental Dynamics of the Ministry of Education of China, Northwest University, Xi’an 710069, China 2. College of Earth Science and Land Resources, Chang’an University, Xi’an 710054, China 3. The Laboratory of Orogen and Basin of the Ministry of Education, Peking University, Beijing 100871, China | 2005 | Science China Earth Sciences2005，48，7： | 38 |
| 7 | Phase I study of chimeric antigen receptor modified T cells in treating HER2-positive advanced biliary tract cancers and pancreatic cancers显示文摘 | Kaichao Feng Yang Liu Yelei Guo Jingdan Qiu Zhiqiang Wu Hanren Dai Qingming Yang Yao Wang Weidong Han1,3 | 2018 | Protein & Cell2018，9，10： | 37 |
| 8 | Sr-Nd isotopic compositions of the Changjiang sediments: Implications for tracing sediment sources显示文摘The suspended particulate and fine-grained floodplain sediments were collected from the main stream and tributaries of the Changjiang River for Sr-Nd isotopic measurements. The εNd(0) values gradually decrease downstream from -10.8 on average in the upper reaches to -12.3 in the lower reaches, whereas the 87Sr/86Sr ratios increase correspondingly, averaging 0.721899 and 0.725826 respectively in the upper and middle-lower reaches. The compositional variations primarily reflect the complex con- trols of provenance rocks, chemical weathering, and sediment characters between different catchments, among which the abnormal Sr-Nd isotopic compositions of the Yalong, Fujiang, Tuojiang and Yuanjiang rivers indicate the sediment provenance contributions from the Emeishan Basalt in the upper reaches and the old metamorphic and siliceous rocks in the middle-lower reaches. The Sr-Nd isotopic ratios of the Changjiang sediments can better reflect the average composition of weathered continental crust compared to other major rivers in the world because of the unique source rock types in the Changjiang drainage basin. The recognition of the Sr-Nd isotopic systematics of the Changjiang sediments will contribute to our understanding of the Changjiang evolution history and continental weathering processes during the Cenozoic, and also to reconstructing the paleoenvironmental changes in East China and the marginal seas. | YANG ShouYe1?, JIANG ShaoYong2, LING HongFei2, XIA XiaoPing3, SUN Min3 & WANG DeJie4 1 State Key Laboratory of Marine Geology, Tongji University, Shanghai 200092, China 2 State Key Laboratory for Mineral Deposit Research, Nanjing University, Nanjing 210093, China 3 Departmen of Earth Sciences, The University of Hong Kong, Hong Kong SAR, China 4 Development Research Center, China Geological Survey, Beijing 100083, China | 2007 | Science China Earth Sciences2007，50，10： | 32 |
| 9 | Hyaluronic acid fragments evoke Kupffer cells via TLR4 signaling pathway显示文摘Kupffer cells, expressing toll-like receptor 4 (TLR4), play a central role in hepatic ischemia/reperfusion (I/R) injury. Hyaluronic acid (HA) fragments, degradative products of high-molecular-weight HA (HMW-HA), acquire the ability to activate immune cells under inflammatory conditions. Here we inves- tigated whether HA fragments could activate Kupffer cells and analyzed the underlying mechanism. Kupffer cells were isolated from wild-type mice (WT, C3H/HeN) and TLR4 mutant mice (C3H/HeJ) and HA fragments were produced by the methods of enzyme digestion and chromatography. Then Kupffer cells were stimulated by HA fragments or other control stimuli. The activation of Kupffer cells was estimated as the release of pro-inflammatory cytokines. The activation of p38 MAPK pathway of Kupffer cells was checked and blocking experiments were done as well. The results indicated that HA fragments acquired the ability to activate Kupffer cells in vitro, which was TLR4 dependent and not due to contamination of lipopolysaccharide. Experiments of p38 MAPK kinase inhibition by SB-203580 verified p38 MAPK was required in HA fragments induced Kupffer cells activation. This suggests that HA fragments, degradative products of one of the major glycosaminoglycans of the extracellular matrix, play critical roles in Kupffer cell activation mediated by TLR4 signaling pathway, which is, at least partially, de- pendent on p38 MAPK activation. | ZHANG JinXiang1, WANG Hui2, XIAO Qing3, LIANG HuiFang4, LI ZhuoYa4, JIANG ChunFang1, WU HeShui5 & ZHENG QiChang5 1 Department of Emergency Surgery, Union Hospital Affiliated to Huazhong University of Science and Technology, Wuhan 430022, China 2 Department of Medical Genetics, Tongji Medical College Affiliated to Huazhong University of Science and Technology, Wuhan 430030, China 3 Department of Ophthalmology, Union Hospital Affiliated to Huazhong University of Science and Technology, Wuhan 430022, China 4 Department of Medical Immunology, Tongji Medical College Affiliated to Huazhong University of Science and Technology, Wuhan 430030, China 5 Department of General Surgery, Union Hospital Affiliated to Huazhong University of Science and Technology, Wuhan 430022, China | 2009 | Science China(Life Sciences)2009，52，2： | 33 |
| 10 | SHRIMP U-Pb dating and Hf isotopic analyses of Middle Ordovician meta-cumulate gabbro in central Qiangtang, northern Tibetan Plateau显示文摘Metabasites consisting of metamorphic ultra-mafic rocks, cumulate gabbro, gabbro (diabase), basalt, and plagiogranite are exposed at the Taoxinghu area in central Qiangtang, northern Tibetan Plateau. Zircon SHRIMP U-Pb dating for the cumulate gabbro yields a weighted mean age of 467±4 Ma, which is the oldest and most reliable magmatic age in this area. Zircon 176Hf/177Hf ratios range from 0.282615 to 0.282657, with εHf(t) values of 5.02±0.28, indicating that the cumulate gabbro was mainly derived from the depleted mantle. In addition, geochemical data of metabasites suggest that they have similar characteristics to those in the mid-ocean ridge basalts (MORB). The Taoxinghu metabasites may represent the fragment of Early Paleozoic ophiolite in the 'Central Uplift' of the Qiangtang, northern Tibetan Plateau. | ZHAI QingGuo1 WANG Jun1, LI Cai2 & SU Li3 1 Institute of Geology, Chinese Academy of Geological Sciences, Beijing 100037, China 2 College of Earth Sciences, Jilin University, Changchun 130061, China 3 The Geological Laboratory Center and State Key Laboratory of Geological Processes and Mineral Resources, China University of Geo- sciences, Beijing 100083, China | 2010 | Science China Earth Sciences2010，53，5： | 31 |
| 11 | Numerical simulation of mechanisms of deformation,failure and energy dissipation in porous rock media subjected to wave stresses显示文摘The pore characteristics,mineral compositions,physical and mechanical properties of the subarkose sandstones were acquired by means of CT scan,X-ray diffraction and physical tests.A few physical models possessing the same pore characteristics and matrix properties but different porosities compared to the natural sandstones were developed.The 3D finite element models of the rock media with varied porosities were established based on the CT image processing of the physical models and the MIMICS software platform.The failure processes of the porous rock media loaded by the split Hopkinson pressure bar(SHPB) were simulated by satisfying the elastic wave propagation theory.The dynamic responses,stress transition,deformation and failure mechanisms of the porous rock media subjected to the wave stresses were analyzed.It is shown that an explicit and quantitative analysis of the stress,strain and deformation and failure mechanisms of porous rocks under the wave stresses can be achieved by using the developed 3D finite element models.With applied wave stresses of certain amplitude and velocity,no evident pore deformation was observed for the rock media with a porosity less than 15%.The deformation is dominantly the combination of microplasticity(shear strain),cracking(tensile strain) of matrix and coalescence of the cracked regions around pores.Shear stresses lead to microplasticity,while tensile stresses result in cracking of the matrix.Cracking and coalescence of the matrix elements in the neighborhood of pores resulted from the high transverse tensile stress or tensile strain which exceeded the threshold values.The simulation results of stress wave propagation,deformation and failure mechanisms and energy dissipation in porous rock media were in good agreement with the physical tests.The present study provides a reference for analyzing the intrinsic mechanisms of the complex dynamic response,stress transit mode,deformation and failure mechanisms and the disaster mechanisms of rock media. | JU Yang1,2,WANG HuiJie1,YANG YongMing1,HU QinAng3 & PENG RuiDong1 1 State Key Laboratory of Coal Resources and Safe Mining,Beijing Key Laboratory of Fracture and Damage Mechanics of Rock and Concrete,China University of Mining and Technology,Beijing 100083,China 2 Department of Mechanical and Manufacturing Engineering,University of Calgary,Calgary,Alberta,T2N 1N4,Canada 3 School of Environment and Civil Engineering,College of Engineering,Oklahoma State University,Stillwater,OK 74078,USA | 2010 | Science China(Technological Sciences)2010，53，4： | 32 |
| 12 | Changes in plant biomass and species composition of alpine Kobresia meadows along altitudinal gradient on the Qinghai-Tibetan Plateau显示文摘Alpine Kobresia meadows are major vegetation types on the Qinghai-Tibetan Plateau. There is growing concern over their relationships among biodiversity, productivity and environments. Despite the im-portance of species composition, species richness, the type of different growth forms, and plant bio-mass structure for Kobresia meadow ecosystems, few studies have been focused on the relationship between biomass and environmental gradient in the Kobresia meadow plant communities, particularly in relation to soil moisture and edaphic gradients. We measured the plant species composition, her-baceous litter, aboveground and belowground biomass in three Kobresia meadow plant communities in Haibei Alpine Meadow Ecosystem Research Station from 2001 to 2004. Community differences in plant species composition were reflected in biomass distribution. The total biomass showed a de-crease from 13196.96±719.69 g/m2 in the sedge-dominated K. tibetica swamp to 2869.58±147.52 g/m2 in the forb and sedge dominated K. pygmaea meadow, and to 2153.08±141.95 g/m2 in the forbs and grasses dominated K. humilis along with the increase of altitude. The vertical distribution of below-ground biomass is distinct in the three meadow communities, and the belowground biomass at the depth of 0-10 cm in K. tibetica swamp meadow was significantly higher than that in K. humilis and K. pygmaea meadows (P<0.01). The herbaceous litter in K. tibetica swamp was significantly higher than those in K. pygnaeca and K. humilis meadows. The effects of plant litter are enhanced when ground water and soil moisture levels are raised. The relative importance of litter and vegetation may vary with soil water availability. In the K. tibetica swamp, total biomass was negatively correlated to species richness (P<0.05); aboveground biomass was positively correlated to soil organic matter, soil moisture, and plant cover (P<0.05); belowground biomass was positively correlated with soil moisture (P<0.05). However, in the K. pygnaeca and K. humilis meadow communities, aboveground biomass was posi-tively correlated to soil organic matter and soil total nitrogen (P<0.05). This suggests that the distribu-tion of biomass coincided with soil moisture and edaphic gradient in alpine meadows. | WANG ChangTing1,3, CAO GuangMin1, WANG QiLan1, JING ZengChun1, DING LuMing1 & LONG RuiJun2 1 Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810001, China 2 College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou 730070, China 3 Graduate University of the Chinese Academy of Sciences, Beijing 100039, China | 2008 | Science China(Life Sciences)2008，51，1： | 31 |
| 13 | Discovery of seep carbonate nodules as new evidence for gas venting on the northern continental slope of South China Sea显示文摘Seep carbonate nodules were firstlycollected from the southwestern Dongsha area onnorthern continental slope of South China Sea formineralogical and geochemical studies. The resultsof X-ray diffraction show that carbonate nodules arecomposed of Fe-rich domolite,siderite and a few cal-cite and aragonite, as well as a small quantity ofnon-carbonate minerals such as goethite, quartz andclay minerals. Fe-rich dolomite and siderite charac-terized by euhedral microcrystalline structure weredirectly precipitated at cold seeps. The δ 13C valuesfor Fe-rich dolomite and siderite in the bulk nodulesvary from ?18.24‰ to ?36.07‰, and the δ 18O valuesrange from 0.42 to 2.76‰. Their moderate depleted13C reflects that carbon origin is possibly thermoge- netic gas or mixed gas, which is evidence of gasventings in the seafloor. Moreover, massive wormtube fossils related to cold seeps were found on thesurfaces of carbonate nodules, and the conduitsand/or channels in semi-solidified nodules whichwere not filled by carbonate or sediment were alsoobserved. A preliminary conclusion is that activemicro gas venting with a conduit/channel diameterrange from 200 μm to 600 μm possibly exists inmodern seafloor of the carbonate nodule area. | CHEN Zhong1,2,3, YAN Wen1,2,3, CHEN Muhong1,3, WANG Shuhong1,2,3, LU Jun1,3, ZHANG Fan1,3, XIANG Rong1,3, XIAO Shangbin1,3, YAN Pin1,2,3 & GU Senchang1,2,3 1. South China Sea Institute of Oceanology, Chinese Academy of Sci-ences, Guangzhou 510301, China 2. Guangzhou Center for Gas Hydrate Research, Chinese Academy of Sciences, Guangzhou 510301, China 3. Key Laboratory of Marginal Sea Geology, South China Sea Institute of Oceanology and Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510301, China | 2006 | Chinese Science Bulletin2006，51，10： | 30 |
| 14 | Production of proinflammatory cytokines in the human THP-1 monocyte cell line following induction by Tp0751,a recombinant protein of Treponema pallidum显示文摘The tissue destruction characteristic of syphilis infection may be caused by inflammation due to Treponema pallidum and the ensuing immune responses to the pathogen.T.pallidum membrane proteins are thought to be potent inducers of inflammation during the early stages of infection.However,the actual membrane proteins that induce inflammatory cytokine production are not known,nor are the molecular mechanisms responsible for triggering and sustaining the inflammatory cascades.In the present study,Tp0751 recombinant protein from T.pallidum was found to induce the production of proinflammatory cytokines,including TNF-α,IL-1βand IL-6,in a THP-1 human monocyte cell line.The signal transduction pathways involved in the production of these cytokines were then further investigated.No inhibition of TNF-a,IL-1β,or IL-6 production was observed following treatment with the SAPK/JNK specific inhibitor SP600125 or with an ERK inhibitor PD98059.By contrast,anti-TLR2 mAb,anti-CD14 mAb,and the p38 inhibitor SB203580 significantly inhibited the production of all three cytokines.In addition,pyrrolidine dithiocarbamate (PDTC),a specific inhibitor of NF-κB,profoundly inhibited the production of these cytokines.Tp0751 treatment strongly activated NF-κB,as revealed by Western blotting.However,NF-κB translocation was significantly inhibited by treatment with PDTC.These results indicated that TLR2,CD14,MAPKs/p38,and NF-κB might be implicated in the inflammatory reaction caused by T.pallidum infection. | LIU ShuangQuan1,2,WANG ShiPing1,WU YiMou3,ZHAO FeiJun3,ZENG TieBing3,ZHANG YueJun3,ZHANG QiuGui2 & GAO DongMei1 1 Department of Parasitology,Xiangya School of Medicine,Central South University,Changsha 410078 ,China 2 The First Affiliated Hospital,University of South China,Hengyan 421001,China 3 Department of Microbiology and Immunology,University of South China,Hengyan 421001,China | 2010 | Science China(Life Sciences)2010，53，2： | 28 |
| 15 | Zircon SHRIMP U-Pb geochronology and petrogenesis of the plagiogranites from the Lagkor Lake ophiolite,Gerze,Tibet,China显示文摘地关系与 petrographical 一起, petrological ,和 geochemicalcharacteristics ,和锆石人口,显示从在 Bangong-Nujiang 缝术地区的 Lagkor Lakeophiolite 的 plagiogranites (~ Gerze 县的 20 km 南方,中央西藏,中国),由在海洋的外壳的运输期间的可锻的砍源于含水的斑粝岩的 anatexis 。因此,这种 plagiogranite 比传播海洋的外壳晚对或很少同时代。锆石虾 166 ±使 2.5 妈变老因为 plagiogranites 显示海洋的盆在中间的侏罗记在 Bangong-Nujiang 地区的西方的部分存在。 | ZHANG YuXiu1,2, ZHANG KaiJun1,3, LI Bing1,2, WANG Yang1,2, WEI QingGuo1,2 & TANG XianChun1,2 1 Key Laboratory of Marginal Sea Geology, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China 2 Graduate University, Chinese Academy of Sciences, Beijing 100039, China 3 Department of Earth Sciences, Nanjing University, Nanjing 210093, China | 2007 | Chinese Science Bulletin2007，52，5： | 27 |
| 16 | Geochemistry and mineralogy of the Late Permian coals from the Songzao Coalfield, Chongqing, southwestern China显示文摘Mineralogy and geochemistry of the four main workable coal seams (No.6, No.7, No.8, and No.11) of Late Permian age from the Songzao Coalfield, Chongqing, Southwest China, were examined using in- ductively coupled plasma-mass spectrometry (ICP-MS), X-ray fluorescence spectrometry (XRF), cold-vapor absorption spectrometry (CV-AAS), ion-selective electrode (ISE), scanning electron mi- croscopy equipped with an energy-dispersive X-ray spectrometer (SEM-EDX), and X-ray diffraction analysis (XRD). The results showed that the main workable No.8 Coal that accounts for about 60% of the total coal reserves in the Songzao Coalfield was not enriched in hazardous trace elements. The No.11 Coal has high concentrations of alkaline elements, Be (9.14 μg/g), Sc (12.9 μg/g), Ti (9508 μg/g), Mn (397 μg/g), Co (23.7 μg/g), Cu (108 μg/g), Zn (123 μg/g), Ga (32 μg/g), Zr (1304 μg/g), Nb (169 μg/g), Hf (32.7 μg/g), Ta (11.4 μg/g), W (24.8 μg/g), Hg (0.28 μg/g), Pb (28.1 μg/g), Th (24.1 μg/g), and rare earth elements (509.62 μg/g). The concentration of Nb and Ta in the No. 11 Coal is higher than the industrial grade, and their potential utilization should be further studied. Besides pyrite, quartz, calcite, and clay minerals, trace minerals including chalcopyrite, marcasite, siderite, albite, mixed-layer clay minerals of illite and smectite, monazite, apatite, anatase, chlorite, and gypsum were found in the No.11 Coal. It should be noted that alabandite of hydrothermal origin and anatase occurring as cement were identi- fied in coal. In addition, the clayey microbands derived from alkaline volcanic ashes were identified in the coal. The dominant compositions of these clayey microbands were mixed-layer clay minerals of illite and smectite, which were interlayered with organic bands. The modes of occurrence of alkaline volcanic ash bands indicate that the volcanic activities were characterized by the multiple eruptions, short time interval and small scale for each eruption during peat accumulation. The alkaline volcanic ashes were the dominant factors for the enrichment of alkaline elements, Nb, Ta, Zr, Hf, and rare earth elements, and the sulfide minerals are the main carriers of Ga, Cu, and Hg in the No. 11 Coal. | DAI ShiFeng1,2, ZHOU YiPing3, REN DeYi1, WANG XiBo1, 2, LI Dan1, 2 & ZHAO Lei1, 2 1 State Key Laboratory of Coal Resources and Safe Mining (China University of Mining and Technology), Beijing 100083, China 2 Department of Resources and Earth Science, China University of Mining and Technology, Beijing 100083, China 3 Kunming Research Institute of Coal Science, Kunming 650041, China | 2007 | Science China Earth Sciences2007，50，5： | 27 |
| 17 | Simulation of energy and water balance in Soil-Vegetation-Atmosphere Transfer system in the mountain area of Heihe River Basin at Hexi Corridor of northwest China显示文摘In the mountain area of inland Heihe River Basin at Hexi Corridor of northwest China during the vegetation growing season from May to September, the Simultaneous Heat and Water (SHAW) model of Soil-Vegetation-Atmosphere Transfer (SVAT) system is applied to simulating and studying energy and water balance of the soil-residue-plant canopy layers in the Picea crassifolia forest and the grassland by the forest at the shaded slope and the grassland at the sun-facing slope. The simulation of energy balance indicates that net radiation of the grass- land at the sun-facing slope is more than that of the Picea crassifolia forest and the grassland by the forest at the shaded slope. The energy outgoing components are the first latent heat and next sensible heat from the grassland both at the shaded slope and the sun-facing slope, but those at the former are less. The energy outgoing components are the first sensible heat and next latent heat from the Picea crassifolia forest. The composition and distribution of energy in the soil-residue-plant canopy layers in the Picea crassifolia forest and the grassland by the forest at the shaded slope make the soil layer receive less energy, which therefore, especially the forest possesses the energy conditions for soil water conservation. The simulation of water balance indicates that the water loss of the grassland at the sun-facing slope is mainly caused by soil evaporation, while evapotranspiration of the Picea crassifolia forest and the grassland by the forest at the shaded slope is less than that of the grassland at the sun-facing slope. Half of the evapotranspiration of the Picea crassifolia forest and the grassland by the forest at the shaded slope is consumed by transpiration. After precipitation, the soil water storage is increased much more for the Picea crassifolia forest and also more for the grassland by the forest at the shaded slope. Therefore the shaded slope vegetation, especially the forest is favorable for soil water storage. | KANG Ersi1, CHENG Guodong1, , SONG Kechao1, JIN Bowen1, , LIU Xiande3 2 3 & WANG Jinye3 1. Cold and Arid Regions Environmental and Engineering Research Institute, Chinese Academy of Sciences, Lanzhou 730000, China 2. State Key Laboratory of Frozen Soil Engineering, Chinese Academy of Sciences, Lanzhou 730000, China 3. Academy of Water Resources Conservation Forest of Qilian Mountains, Gansu Province, Zhangye 734000, China | 2005 | Science China Earth Sciences2005，48，4： | 25 |
| 18 | The prognostic value of preoperative serum levels of CEA,CA19-9 and CA72-4 in patients with colorectal cancer显示文摘INTRODUCTIONCarcinoembryonic antigen ( CEA) , originally described by Gold and Freedman [1] in 1965, is now an acknowledged member of immunoglobulin superfamily[2],with a role as an intracellular adhesion molecule[3].Carbohydrate antigen 19-9(CA19-9), obtained with a monoclonal antibody produced by immunizing a monoclonal antibody produced by immunizing a mouse with a colonic cancer cell line in 1979[4],is a ligand for E-selectin that plays an important role in the addhesion of cancer cells to endothelial cells [5,6]. | Chao Xu Zheng~1 Wen Hua Zhan~1 Ji Zong Zhao~2 Dong Zheng~3 Dong Ping Wang~1 Yu Long He~1 Zhang Qing Zheng~1 ~1Department of General Surgery,~2Laboratory of Surgery,~3Department of Medicine,First Affiliated Hospital,Sun Yat-Sen University of Medical Sciences,Guangzhou 510080,Guangdong Province,ChinaDr.Chao Xu Zheng now working as a surgeon and lecturer in the Department of General Surgery,First Affiliated Hospital,Sun Yat-Sen University of Medical Sciences,who is a Ph.D.student,having 7 papers published. | 2001 | World Journal of Gastroenterology2001，7，3： | 25 |
| 19 | Different Effects of Homocysteine and Oxidized Low Density Lipoprotein on Methylation Status in the Promoter Region of the Estrogen Receptor α Gene显示文摘我们调查了人的效果半胱氨酸(Hcy ) 和在雌激素受体高山的倡导者区域的 DNA methylation 上的氧化低密度脂蛋白(ox-LDL ) 哈(ERalpha ) 基因,和它在动脉粥样硬化的致病的潜在的机制。人的有教养的光滑的肌肉房间(SMC ) 被 Hcy 和 ox-LDL 为时间的不同经期与不同集中对待。DNA methylation 地位是由嵌套的 methylation 特定的聚合酶链反应的 assayed,在 SMC 和泡沫房间形成积累了的类脂化合物被检验,油红 O 染色。SMC 的增长是由 the3-(4,5-dimethylthiazol-2-yl ) 的 assayed -2,5-diphenyltetrazolium 溴化物方法。结果证明 ox-LDLin 节制导致的集中(10-40 mg/L ) 在 SMCs.However 的 ERagene 的倡导者区域的 de novo methylation, ox-LDL 的高集中(50 mg/L ) ,导致了时代的 demethylation。 Hcytreatment 与 aconcentration 在时代基因的倡导者区域导致了 de novo methylation --并且对待时间依赖者举止,并且在 SMCproliferation.These 数据上支持效果的一个剂量依赖者显示为动脉粥样硬化的二个风险因素有在 SMCs.However 的时代基因的倡导者区域导致 de novo methylation 的功能, ox-LDL 的高集中( 50 mg/L )导致了 demethylation ,显示有不同力量力量的动脉粥样硬化的不同风险因素在时代基因的倡导者区域引起不同异常 methylation 模式。Hcy 的 atherogenic 机制可能包含 hypermethylationof 时代基因,在动脉粥样硬化患者损害导致 SMC 的增长。 | Yushan HUANG~1 Kejun PENG~2 Juan SU~1 Yuping HUANG~3 Yizhon XU~1 and Shuren WANG~1 ~1Department of Pathophysiology,West China School of Preclinic Medical Sciences & Forensic Medicine,Sichuan University,Chengdu 610041.China ~2Department of Laboratory Medicine,Chengdu Medical College,Chengdu 610500,China ~3Department of Biochemistry and Molecular Bilogy,Gannan Medical College,Ganzhou 341000,China | 2007 | Acta Biochimica et Biophysica Sinica2007，39，1： | 25 |
| 20 | Randomization of classical inference patterns and its application显示文摘By means of randomization, the concept of D-randomized truth degree of formulas in two-valued propositional logic is introduced, and it is proved that the set of values of D-randomized truth degree of formulas has no isolated point in [0,1]. The concepts of D-logic pseudo-metric and D-logic metric space are also introduced and it is proved that there is no isolated point in the space. The new built D-randomized concepts are extensions of the corresponding concepts in quantified logic. Moreover, it is proved that the basic logic connectives are continuous operators in D-logic metric space. Lastly, three different types of approximate reasoning patterns are proposed. | WANG GuoJun1,2 & HUI XiaoJing1,31 Institute of Mathematics, Shaanxi Normal University, Xi’an 710062, China 2 Research Center for Science, Xi’an Jiaotong University, Xi’an 710049, China 3 College of Mathematics and Computer Science, Yan’an University, 716000, China | 2007 | Science in China(Series F)2007，50，6： | 26 |
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