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| 1 | Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial显示文摘 | Roger Stupp Monika E Hegi Warren P Mason Martin J van den Bent Martin JB Taphoorn Robert C Janzer Samuel K Ludwin Anouk Allgeier Barbara Fisher Karl Belanger Peter Hau Alba A Brandes Johanna Gijtenbeek Christine Marosi Charles J Vecht Karima Mokhtari Piet | 2009 | Lancet Oncology2009，，5： | 4 |
| 2 | Ovarian autoimmune disease: clinical concepts and anima models显示文摘卵巢不是一个 immunologically 给予优惠的机关,但是在为卵巢特定的抗原的 tolerogenic 机制的一个故障在生育力上有灾难性的后果在里面女人,和这在自体免疫的疾病的鼠科的模型被复制。孤立的卵巢的自体免疫的疾病在女人是稀罕的,由于疾病和无能到的严厉可能播送越过代授与卵巢的疾病的基因信息。尽管如此,自体免疫的卵巢炎经常与另外的自体免疫的疾病联合被观察,特别地自体免疫的肾的疾病,并且在社会和单个健康上拿使用费。在老鼠的研究揭示了保护卵巢免受自体免疫的攻击的伤害的至少二机制。这些机制为自体免疫的管理者(亚耳河) 由导出胸腺的规章的 T 房间,以及一个角色包括 autoreactive T 房间的控制,在髓的 thymic 导致限制织物的抗原的表示的一个 transcriptional 管理者上皮的房间在 T 房间的开发期间。尽管后者机制不完全地被定义,也的失败导致自体免疫调停指向和卵巢的滤泡的弄空,这很好被建立。在这评论,我们将探讨自体免疫调停的临床的特征和后果在女人的卵巢的不孕,以及由动物揭示了的疾病的可能的机制当模特儿。 | Bryce D Warren William K Kinsey Lynda K McGinnis Lane K Christenson Susmita Jasti Anne M Stevens Brian K Petroff Margaret G Petroff | 2014 | Cellular & Molecular Immunology2014，11，6： | 3 |
| 3 | Hyperspectral versus multispectral data for estimating leaf area index in four different biomes显示文摘 | Kyu-Sung Lee Warren B Cohen Robert E Kennedy Thomas K Maiersperger Stith T Gower | 2004 | Remote Sensing of Environment2004，，3： | 2 |
| 4 | A prospective trial of volumetric intensity-modulated arc therapy vs conventional intensity modulated radiation therapy in advanced head and neck cancer显示文摘AIM: To prospectively compare volumetric intensitymodulated arc therapy(VMAT) and conventional intensity-modulated radiation therapy(IMRT) in coverage of planning target volumes and avoidance of multiple organs at risk(OARs) in patients undergoing definitive chemoradiotherapy for advanced(stage Ⅲ or Ⅳ)squamous cell cancer of the head and neck. METHODS: Computed tomography scans of 20 patients with advanced tumors of the larynx, naso-, oroand hypopharynx were prospectively planned using IMRT(7 field) and VMAT using two arcs. Calculated doses to planning target volume(PTV) and OAR were compared between IMRT and VMAT plans. Dose-volume histograms(DVH) were utilized to obtain calculated doses to PTV and OAR, including parotids, cochlea,spinal cord, brainstem, anterior tongue, pituitary and brachial plexus. DVH's for all structures were compared between IMRT and VMAT plans. In addition the planswere compared for dose conformity and homogeneity. The final treatment plan was chosen by the treating radiation oncologist. RESULTS: VMAT was chosen as the ultimate plan in 18 of 20 patients(90%) because the plans were thought to be otherwise clinically equivalent. The IMRT plan was chosen in 2 of 20 patients because the VMAT plan produced concentric irradiation of the cord which was not overcome even with an avoidance structure. For all patients, VMAT plans had a lower number of average monitor units on average(MU = 542.85) than IMRT plans(MU = 1612.58)(P < 0.001). Using the conformity index(CI), defined as the 95% isodose volume divided by the PTV, the IMRT plan was more conformal with a lower conformity index(CI = 1.61) than the VMAT plan(CI = 2.00)(P = 0.003). Dose homogeneity, as measured by average standard deviation of dose distribution over the PTV, was not different with VMAT(1.45 Gy) or IMRT(1.73 Gy)(P = 0.069). There were no differences in sparing organs at risk.CONCLUSION: In this prospective study, VMAT plans were chosen over IMRT 90% of the time. Compared to IMRT, VMAT plans used only one third of the MUs, had shorter treatment times, and similar sparing of OAR. Overall, VMAT provided similar dose homogeneity but less conformity in PTV irradiation compared to IMRT. This difference in conformity was not clinically significant. | Simon D Fung-Kee-Fung Rachel Hackett Lee Hales Graham Warren Anurag K Singh | 2012 | World Journal of Clinical Oncology2012，3，4： | 2 |
| 5 | Investigation of precipitation in an Al-Zn-Mg alloy after twostep ageing treatment at 100 ℃ and 150 ℃显示文摘 | Warren P J Hansen V | 1999 | Material Science and Engineering A1999，270，： | 1 |
| 6 | Factors associated with dental caries experience in 1-year-old children显示文摘 | Warren JJ Weber-Gasparoni K Marshall TA | 2008 | J Public Health Dent2008，68，2： | 1 |
| 7 | Surface disturbance of cryptobiotic soil crusts: Nitrogenase activity,chlorophyll content,and chlorophyll degradation显示文摘 | Belnap J Harper K T Warren S D | 1994 | Arid Soil Research and Rehabilitation1994，8，： | 1 |
| 8 | The program dependence graph and its use in optimization显示文摘 | Ferrante J Ottenstein K J Warren J D | 1987 | ACM Transactions on Programming Languages and Systems1987，9，3： | 1 |
| 9 | Investigation of precipitation in an Al-Zn-Mg alloy after two-step aging treatment at 100℃ and 150 ℃显示文摘 | Stiller K Warren P J Hansen V | 1999 | Mater Sci Eng A1999，270，： | 1 |
| 10 | Surface passivation of bare aluminum nanoparticles using perfluoroalkyl carboxylic acids 显示文摘 | JOUET R J WARREN A D ROSENBERG D M BELITTO V J PARK K ZACHARIAH M R | 2005 | Chem Mater2005，17，11： | 1 |
| 11 | The microfrature technique for the treatment of artiatar cartilage lesions in the knee显示文摘 | Mithoefer K Williars RJ Warren RF | 2005 | J Bone Joint Surg Am2005，8，6： | 1 |
| 12 | Investigation of precipitation in an AI-Zn-Mg alloy aftcr two-step ageing treatment at 100 C and 150 C 显示文摘 | STILLER K WARREN P HANSEN V ANGENETE J GJNNES J | 1999 | Mater Sci Eng A1999，270，1： | 1 |
| 13 | Finite element analysis of a single bead-on-plate specimen using SYSWELD 显示文摘 | Bate S K Charles R and Warren A | 2009 | International Journal of Pressure Vessels and Piping2009，，86： | 1 |
| 14 | Relationships between Leaf Area Index and Landsat TM Spectral Vegetation Indices across Three Temperate Zone Sites 显示文摘 | David PT Warren B C Robert E K | 1999 | Remote Sensing of Environment1999，70，： | 1 |
| 15 | The contribution of nuclear reactions to heavy ion single event upset cross-section measurements in a high- density SEU hardened SRAM 显示文摘 | WARREN K M WELLER R A MENDENHALL M H | 2005 | IEEE Transactions on Nuclear Science2005，52，6： | 1 |
| 16 | Surface disturbance of cryptobiotic soil crusts: nitrogenase activity, chlorophyll content and chlorophyll degradation 显示文摘 | Belnap J Harper K T Warren S D | 1994 | Arid Soil Research and Rehabilitation1994，8，： | 1 |
| 17 | DNA polymorphism analysis in transfusion-associated grafe-versus-host disease显示文摘 | Warren LJ Simmer K Roxby D | 1999 | J Paediatr Child Health1999，35，1： | 1 |
| 18 | Resultsfrom the 1995 national college health risk behavior survey显示文摘 | Douglas K A Collins J L Warren C | 1997 | J Am College Health1997，46，2： | 1 |
| 19 | A new quation equation of state (QEOS) for hot dense matter显示文摘 | More R M Warren K H Young D A | | 0，，： | 1 |
| 20 | Selective primary health care: an interim strategy for disease control in developing countries显示文摘 | Walsh J A Warren K S | 1979 | N Engl J Med1979，301，18： | 1 |
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