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| 1 | 2018年急性缺血性卒中患者早期管理指南美国心脏协会/美国卒中协会为医疗专业人员制定的指南显示文摘背景和目的本指南旨在在单个文件中为治疗成年急性动脉性缺血性卒中患者的临床医生提供最新全面的系列推荐意见。目标读者为院前急救人员、医生、综合医疗保健人员和医院管理人员。本指南将取代2013年版指南及其后续更新。方法写作组成员由美国心脏协会卒中委员会的科学声明监督委员任命,代表各领域的医学专家。严格遵循美国心脏协会的利益冲突原则。不允许写作组成员对存在企业利益关系的相关议题进行讨论或投票。所有推荐意见必须得到写作组成员的一致通过,除非企业利益关系妨碍了成员投票。由4名同行评议专家以及卒中委员会的科学声明监督委员会和领导委员会成员对指南草案进行发布前评审。本指南采用了美国心脏病学学会/美国心脏协会2015年推荐意见分类和证据级别标准以及新版美国心脏协会指南格式。结果本指南详细介绍了院前医疗、紧急和急诊评估、静脉和血管内治疗以及院内管理,包括在发病后最初2周内启用的二级预防措施。本指南支持院前和院内卒中医疗系统的一体化概念。结论本指南基于目前可获得的最佳证据。然而,许多情况资料有限,迫切需要对急性缺血性卒中的治疗进行持续研究。 | William J. Powers Alejandro A. Rabinstein Teri Ackerson Opeolu M. Adeoye Nicholas C. Bambakidis Kyra Becker José Biller Michael Brown Bart M. Demaerschalk Brian Hoh Edward C. Jauch Chelsea S. Kidwell Thabele M. Leslie-Mazwi Bruce Ovbiagele Phillip A. Scott Kevin N. Sheth Andrew M. Southerland Deborah V. Summers David L. Tirschwell 徐加平 刘慧慧 张霞 石际俊 黄志超 尤寿江 郭志良 肖国栋 杜万良 曹勇军 | 2018 | 国际脑血管病杂志2018，26，2： | 19 |
| 2 | 2019年急性缺血性卒中患者早期管理指南:针对2018年急性缺血性卒中早期管理指南的更新美国心脏协会/美国卒中协会为医疗专业人员制定的指南显示文摘背景和目的本指南旨在在单个文件中为治疗急性动脉性缺血性卒中患者的临床医生提供最新的全面系列推荐意见。目标读者为院前急救人员、医生、综合医疗保健人员以及医院管理人员。本指南将取代2013年版急性缺血性卒中(acute ischemic stroke,AIS)指南,同时也是对2018年版AIS指南的更新。方法写作组成员由美国心脏协会(American Heart Association,AHA)卒中委员会的科学声明监督委员会任命,代表各领域的医学专家。写作组成员不得对存在企业利益关系的相关议题进行讨论或投票。对2013年版AIS指南的更新最初于2018年1月发表,该版指南已经过AHA科学咨询与协调委员会以及AHA执行委员会批准。2018年4月,在删除部分推荐意见后,该指南的修订版在AHA网站上在线发表。要求写作组审查原始文件并在必要时进行修订。2018年6月,写作组提交了一份经过细微更改并纳入新近发表的重要随机对照试验(受试者数量>100名且具有AIS发病后至少90 d的临床转归)的文件。经过14位专家进行同行评议后,写作组根据同行评议专家的意见进行了适当修改。目前的最终文件已经过写作组全体成员(除非企业利益关系妨碍了成员投票)以及AHA管理机构批准。本指南采用了美国心脏病学学会/AHA 2015年推荐意见分类和证据级别标准以及新版AHA指南格式。结果本指南详细介绍了院前医疗、紧急和急诊评估、静脉和血管内治疗以及院内管理,包括在发病后最初2周内启用的二级预防措施。本指南支持院前和院内卒中医疗系统的一体化概念。结论本指南基于现有证据提供了总体推荐意见,用于指导治疗成年急性动脉性缺血性卒中患者的临床医生。然而,许多情况资料有限,迫切需要对AIS的治疗进行持续研究。 | William J.Powers Alejandro A.Rabinstein Teri Ackerson Opeolu M.Adeoye Nicholas C.Bambakidis Kyra Becker Jose Biller Michael Brown Bart M.Demaerschalk Brian Hoh Edward C.Jauch Chelsea S.Kidwell Thabele M.Leslie-Mazwi Bruce Ovbiagele Phillip A.Scott Kevin N.Sheth Andrew M.Southerl Deborah V.Summers Tirschwell 徐加平(译) 庄圣(译) 郭志良(译) 黄志超(译) 尤寿江(译) 刘慧慧(译) 张霞(译) 石际俊(译) 肖国栋(译) 曹勇军(译) 刘春风(译) | 2020 | 国际脑血管病杂志2020，28，1： | 18 |
| 3 | Transradial versus transfemoral access for anterior circulation mechanical thrombectomy: analysis of 375 consecutive cases显示文摘Objective To compare transradial artery access(TRA)to the gold standard of transfemoral artery access(TFA)in mechanical thrombectomy(MT)for stroke caused by anterior circulation large vessel occlusion.Methods The clinical outcomes,procedural speed,angiographic efficacy and safety of both techniques were analysed in 375 consecutive cases over an 18-month period in a high volume statewide neurointerventional service.Results There was no significant difference in patient characteristics,stroke parameters,imaging techniques or intracranial techniques.The median time elapsed between CT scanning and reperfusion was 96.5 min(IQR 68-123)in the TFA group and 95 min(IQR 68-123)in the TRA group(p=0.456).Of 336 patients who were independent at presentation 58%(124/214)of the TFA group and 67%(82/122)of the TRA group had a modified Rankin score of 0-2 at 90-day follow-up(p=0.093).Cross-over from radial to femoral was 4.6%(4/130)compared with 1.6%cross-over from femoral to radial(4/245),but did not meet the predetermined level of statistical significance(OR2.92,95% CI 0.81 to 10.52,p=0.088) and did not impact median procedural speed.Adequate angiographic reperfusion,first pass reperfusion,embolisation to new territory and symptomatic intracranial haemorrhage were similar in both groups.There was a significant difference in major access site complications requiring an additional procedure.None of the TRA cases had a major access site complication but 6.5%(16/245)of the TFA cases did(p=0.003).Conclusion This study suggests that using TRA for anterior circulation MT is fast,efficacious,safe and not inferior to the gold standard of TFA. | Timothy John Phillips Matthew Thomas Crockett Gregory D Selkirk Ruchi Kabra Albert Ho Yuen Chiu Tejinder Singh Constantine Phatouros William McAuliffe | 2021 | Stroke & Vascular Neurology2021，6，2： | 7 |
| 4 | Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial显示文摘 | Eric Lawitz Fred F Poordad Phillip S Pang Robert H Hyland Xiao Ding Hongmei Mo William T Symonds John G McHutchison Fernando E Membreno | 2013 | The Lancet2013，，： | 5 |
| 5 | Modulation of the fecal bile acid profile by gut microbiota in cirrhosis显示文摘 | Genta Kakiyama William M. Pandak Patrick M. Gillevet Phillip B. Hylemon Douglas M. Heuman Kalyani Daita Hajime Takei Akina Muto Hiroshi Nittono Jason M. Ridlon Melanie B. White Nicole A. Noble Pamela Monteith Michael Fuchs Leroy R. Thacker Masoumeh Sikaro | 2013 | Journal of Hepatology2013，，5： | 3 |
| 6 | Jaundice: an important, poorly recognized risk factor for diminished survival in patients with adenocarcinoma of the head of the pancreas显示文摘 | Steven M. Strasberg Feng Gao Dominic Sanford David C. Linehan William G. Hawkins Ryan Fields Danielle H. Carpenter Elizabeth M. Brunt Carolyn Phillips | 2014 | HPB2014，，2： | 2 |
| 7 | Usefulness of B-Type Natriuretic Peptide and Cardiac Troponin Levels to Predict In-Hospital Mortality from ADHERE显示文摘 | Gregg C. Fonarow William F. Peacock Tamara B. Horwich Christopher O. Phillips Michael M. Givertz Margarita Lopatin Janet Wynne | 2008 | The American Journal of Cardiology2008，，2： | 2 |
| 8 | Differential utilization of summer rains by desert plants显示文摘 | James R. Ehleringer Susan L. Phillips William S. F. Schuster Darren R. Sandquist | 1991 | Oecologia1991，，3： | 2 |
| 9 | Mechanical thrombectomy with the S olitaire AB device in large intracerebral artery occlusions显示文摘 | John J McCabe Timothy J Phillips Con Phatouros Tejinder Singh David Blacker Graeme J Hankey William McAuliffe | 2012 | Journal of Medical Imaging and Radiation Oncology2012，，2： | 2 |
| 10 | Comment on profitability analysis of a femtosecond laser system for cataract surgery using a fuzzy logic approach显示文摘Dear Editor,We read with interest the recently published study by Trigueros et al^([1]),highlighting the financial and management conditions of femtosecond laser-assisted cataract surgery(FLACS).The authors derived a simulation to | Harrv William Roberts Melody Zhifang Ni David Phillip S. O'Brart | 2017 | International Journal of Ophthalmology(English edition)2017，10，3： | 2 |
| 11 | Human aflatoxicosis in developing countries:a review of toxicology,exposure,potential health consequences,and interventions显示文摘 | Williams JH Phillips TD Jolly PE | 2004 | Am J Clin Nutr2004，80，5： | 1 |
| 12 | An infrared and Raman spectroscopic study of gypsum at high pressures 显示文摘 | Knittle E Phillips W Williams Q | 2001 | Phys Chem Miner2001，28，9： | 1 |
| 13 | The effect of short - term withdrawal from continuous positive airway pressure therapy on sym- pathetic activity and markers of vascular inflammation in subjects with obstructive sleep apneea显示文摘 | Phillips CL Yang Q Williams A | 2007 | J Sleep Res2007，16，2： | 1 |
| 14 | Laser Deceleration of an Atomic Beam显示文摘 | PHILLIPS WILLIAM D HAROLD METCALF | 1982 | Phys Rev Lett1982，48，9： | 1 |
| 15 | Fusarium dry rot显示文摘 | Phillip W Ray H William K | 2007 | Michigan Potato Diseases Extension Bulletin2007，，： | 1 |
| 16 | Proteasome inhibitor PS519 reduces infarction and at- tenuates leukocyte infiltration in a rat model of focal cerebral ischemia显示文摘 | PHILLIPS J B WILLIAMS A J ADAMS J | 2000 | Stroke2000，31，： | 1 |
| 17 | Increased Plasma and Platelet to Red Blood Cell Ratios Improves Outcome in 466 Massively Transfused Civilian Trauma Patients显示文摘 | John B. Holcomb Charles E. Wade Joel E. Michalek Gary B. Chisholm Lee Ann Zarzabal Martin A. Schreiber Ernest A. Gonzalez Gregory J. Pomper Jeremy G. Perkins Phillip C. Spinella Kari L. Williams Myung S. Park | 2008 | Annals of Surgery2008，，3： | 1 |
| 18 | Implementation of a pharmacy residency in a Veterans Affairs community-based outpatient clinic显示文摘 | BETH BRYLES PHILLIPS KIM C. WILLIAMS | 2012 | American Journal of Health-System Pharmacy2012，，10： | 1 |
| 19 | An Infrared and Raman Spectroscopic Study of Gypsum at High Pressures 显示文摘 | Knittle E Phillips W Williams Q | 2001 | Phys Chem Miner2001，28，： | 1 |
| 20 | Comparisons of carbon isotope discrimination in populations of aridland plant species differing in lifespan显示文摘 | William S. F. Schuster Darren R. Sandquist Susan L. Phillips James R. Ehleringer | 1992 | Oecologia1992，，3： | 1 |
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