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| 1 | 东准噶尔盆地巴塔玛依内山组火山岩锆石U-Pb年代及Hf同位素研究显示文摘对准噶尔盆地陆梁隆起东部三参1井所钻巴塔玛依内山组玄武岩,开展了详细锆石内部结构研究基础上的U-Pb年代学、微量元素和Hf同位素系统分析.结果显示,所有锆石都属岩浆成因,都有一致的稀土配分型式,都具明显的Ce正异常(δCe=5.06~134)、Eu负异常(δEu=0.06~0.55)和重稀土元素富集特征.25颗锆石中,谐和年龄主要分成3组,分别是(300.4±1.3)Ma(n=11),(339.2±2.7)Ma(n=3)和(392.0±1.7)Ma(n=8);此外,还有3颗近谐和年龄锆石,它们的206Pb/238U年龄分别是(510±7),(488±6)和(453±6)Ma.最小的谐和年龄为(300.4±1.3)Ma,可以代表巴塔玛依内山组火山岩的形成时代(如晚阶段年龄).其他年龄如早泥盆世、奥陶纪等,与盆地周缘岛弧火山岩(富集Pb)和蛇绿岩的时代一致,而且这些年龄锆石都具有正的εHf(t)值(+3.6^+10.5),推测所研究火山岩穿越的盆地基底,可能与由早古生代-中古生代的残余洋壳和岛弧地体组成有关.晚石炭世锆石的εHf(t)值变化于+17.1^+4.2,显示该玄武岩主要来源于软流圈地幔或亏损岩石圈地幔熔融作用,熔体在上升-侵位过程中混染了少量较古老基底物质组分.由于这些玄武岩是后碰撞幔源岩浆直接加入到地壳的物质表现,推测东准噶尔地区晚石炭世已经有了大规模的陆壳垂向生长过程. | 苏玉平 郑建平 Griffin William L 汤华云 O'Reilly Suzanne Y 林向洋 | 2010 | 科学通报2010，55，30： | 50 |
| 2 | Evaluating the performance of nanostructured materials as lithium-ion battery electrodes显示文摘锂离子房间的性能重重地依赖于主机电极的能力从本地结构提供并且释放 Li+ 离子。当电极材料的选择可以定义象房间潜力和能力那样的参数时,置闰的过程可以被率身体上限制固态 Li+ 散开。在锂离子电极的增加的散开率可以在散开路径通过减小被完成,由一可伸缩各自的电极尺寸完成了。另外,一些电极可以经历与收费并且排出联系的大体积变化,的紧张,可以更好通过 nanostructuring 被提供。主机的失败可以导致本地结构的 pulverisation 和能力的快速的损失提供如此的卷变化。在这篇评论文章,我们寻求在 nanostructured 锂离子电池体系结构(阳极和阴极) 的开发加亮很多重要获得,作为潜在的下一代的电气化学的精力存储设备的驱动程序。 | Mark J. Armstrong Colm O'Dwyer William J. Macklin Justin. D. Holmes | 2014 | Nano Research2014，7，1： | 23 |
| 3 | 建筑中人行为模拟研究现状和展望显示文摘人行为是影响建筑能耗的重要因素,近几年成为建筑能耗模拟领域的研究热点。在过去的几十年中已有大量的相关研究,致力于通过实测建立事件或环境相关的人行为模型,但是,目前的人行为研究中还需要进一步发展,以满足工程实际的需要。本文回顾了人行为研究的研究现状,总结了在研究方法上现存的问题,从数据采集、模型建立、模型验证和软件开发4个从建模到应用的阶段,提出了人行为研究的未来展望。并讨论了人行为研究中尚存在的一些共性问题,例如:在实测中应进一步探讨采样的规模和实验室研究的可行性,建立人行为模型时应明确模型面向的应用层次,合理的数学形式、参数选择的方法、多因素多行为多人的模拟等尚待研究,针对模型的验证应以实际应用为指向确定验证的指标,采取科学有效的验证方法,以及在人行为相关软件的开发中,应定义良好的软件结构和接口,建立统一的描述框架,以相对独立的模块形式实现和模拟软件的交互。希望这些探讨能为将来的人行为研究提供新的思路,以推动人行为和建筑能耗模拟事业的发展。 | 燕达 丰晓航 王闯 Hong Tianzhen William O’Brien H.Burak Gunay Farhang Tahmasebi Ardeshir Mahdavi | 2015 | 建筑科学2015，31，10： | 23 |
| 4 | Zircon U-Pb and Hf isotopes of volcanic rocks from the Batamayineishan Formation in the eastern Junggar Basin显示文摘内部结构的研究被进行从 Batamayineishan 形成调查 U-Pb 年龄,踪迹元素和玄武岩的锆石的 Hf 同位素。暗岩从练习井圣罐头被获得 1 在 Junggar 盆以内在东方 Luliang 上高举。跟踪所有样品是 magmatic 的锆石表演的元素数据,与类似的 REE 模式,包括积极 Ce (Ce=5.06134 ) ,而是否定 Eu (Eu=0.06 ? 0.55 ) 在重稀土元素元素的异例和丰富。在 25 谷物之中,一致年龄被细分进三个组;300.4 整潲祺潧整的年龄? | SU YuPing ZHENG JianPing GRIFFIN William L TANG HuaYun O'REILLY Suzanne Y LIN XiangYang | 2010 | Chinese Science Bulletin2010，55，36： | 21 |
| 5 | 古老大陆岩石圈地幔再循环与蛇绿岩中铬铁矿床成因显示文摘不同地区、不同时代蛇绿岩中不同类型铬铁矿岩的Re-Os同位素研究表明,在铬铁矿石或围岩中均存在极度亏损的具有大陆岩石圈地幔属性的物质。新疆达拉布特古生代蛇绿岩带中萨尔托海富Al铬铁矿岩的Os同位素组成为0.1109~0.1256,对应的模式年龄为3.5~0.6Ga;西藏班公湖—怒江中生代蛇绿岩带中东巧富Cr铬铁矿石及围岩Os同位素组成介于0.1175~0.1261,对应的模式年龄为1.5~0.1Ga;雅鲁藏布江中生代蛇绿岩带中罗布莎富Cr铬铁矿岩的Os同位素变化范围为0.1038~0.1266,对应的模式年龄为3.37~0.28Ga,而该带中不含矿的泽当二辉橄榄岩的Os同位素组成为0.1256~0.1261,没有古老大陆岩石圈地幔属性的物质存在,与新特提斯洋地幔Os组成较为接近。推测在蛇绿岩形成过程中,古老大陆岩石圈地幔参与循环有利于形成铬铁矿床,明确提出'熔体与古老大陆岩石圈地幔反应成矿'的假说,指出蛇绿岩带中存在的古老微陆块可能是找矿的指示标志。 | 史仁灯 黄启帅 刘德亮 樊帅权 张晓冉 丁林 William L GRIFFIN Suzanne Y O'REILLY | 2012 | 地质论评2012，58，4： | 15 |
| 6 | Performance characterization of Ni60-WC coating on steel processed with supersonic laser deposition显示文摘Ni60-WC particles are used to improve the wear resistance of hard-facing steel due to their high hardness. An emerging technology that combines laser with cold spraying to deposit the hard-facing coatings is known as supersonic laser deposition. In this study, Ni60-WC is deposited on low-carbon steel using SLD. The microstructure and performance of the coatings are investigated through SEM, optical microscopy, EDS, XRD, microhardness and pin-on-disc wear tests. The experimental results of the coating processed with the optimal parameters are compared to those of the coating deposited using laser cladding. | Fang LUO Andrew COCKBURN Martin SPARKES Rocco LUPOI Zhi-jun CHEN William O'NEILL Jian-hua YAO Rong LIU | 2015 | Defence Technology(防务技术)2015，11，1： | 11 |
| 7 | Passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts and assessment of clinical outcomes显示文摘AIM To assess for passive expansion of sub-maximally dilated transjugular intrahepatic portosystemic shunts(TIPS) and compare outcomes with maximally dilated TIPS.METHODS Polytetrafluoroethylene covered TIPS(Viatorr) from July 2002 to December 2013 were retrospectively reviewed at two hospitals in a single institution. Two hundred and thirty patients had TIPS maximally dilated to 10 mm(m TIPS), while 43 patients who were at increased risk for hepatic encephalopathy(HE), based on clinical evaluation or low pre-TIPS portosystemic gradient(PSG), had 10 mm TIPS sub-maximally dilated to 8 mm(sm TIPS). Group characteristics(age, gender, Model for End-Stage Liver Disease score, post-TIPS PSG and clinical outcomes were compared between groups, including clinical success(ascites or varices), primary patency,primary assisted patency, and severe post-TIPS HE. A subset of fourteen patients with sm TIPS underwent follow-up computed tomography imaging after TIPS creation, and were grouped based on time of imaging(< 6 mo and > 6 mo). Change in diameter and crosssectional area were measured with 3D imaging software to evaluate for passive expansion.RESULTS Patient characteristics were similar between the sm TIPS and m TIPS groups, except for pre-TIPS portosystemic gradient, which was lower in the sm TIPS group(19.4 mm Hg ± 6.8 vs 22.4 mm Hg ± 7.1, P = 0.01). Primary patency and primary assisted patency between sm TIPS and m TIPS was not significantly different(P = 0.64 and 0.55, respectively). Four of the 55 patients(7%) with sm TIPS required TIPS reduction for severe refractory HE, while this occurred in 6 of the 218 patients(3%) with m TIPS(P = 0.12). For the 14 patients with follow-up computed tomography(CT) imaging, the median imaging follow-up was 373 d. There was an increase in median TIPS diameter, median percent diameter change, median area, and median percent area change in patients with CT follow-up greater than 6 mo after TIPS placement compared to follow-up within 6 mo(8.45 mm, 5.58%, 56.04 mm^2, and 11.48%, respectively, P = 0.01).CONCLUSION Passive expansion of sm TIPS does occur but clinical outcomes of sm TIPS and m TIPS were similar. Sub-maximal dilation can prevent complications related to overshunting in select patients. | Michael C Hsu Charles N Weber S William Stavropoulos Timothy W Clark Scott O Trerotola Richard D Shlansky Goldberg Michael C Soulen Gregory J Nadolski | 2017 | World Journal of Hepatology2017，9，12： | 11 |
| 8 | Pre-and postoperative systemic hemodynamic evaluation in patients subjected to esophagogastric devascularization plus splenectomy and distal splenorenal shunt:A comparative study in schistomomal portal hypertension显示文摘AIM: To investigate the systemic hemodynamic effects of two surgical procedures largely employed for treatment of schistosomal portal hypertension. METHODS: Thirty-six patients undergoing elective surgical treatment of portal hypertension due to hepatosplenic mansonic schistosomiasis were prospectively evaluated. All patients were subjected to preoperative pulmonary artery catheterization; 17 were submitted to esophagogastric devascularization and splenectomy (EGDS) and 19 to distal splenorenal shunt (DSRS). The systemic hemodynamic assessment was repeated 4 d after the surgical procedure. RESULTS: Preoperative evaluation revealed (mean ± SD) an increased cardiac index (4.78 ± 1.13 L/min per m2),associated with a reduction in systemic vascular resistance index (1457 ± 380.7 dynes.s/cm5.m2). The mean pulmonary artery pressure (18 ± 5.1 mmHg) as well as the right atrial pressure (7.9 ± 2.5 mmHg) were increased,while the pulmonary vascular resistance index (133 ± 62 dynes.s/cm5.m2) was decreased. Four days after EGDS,a significant reduction in cardiac index (3.80 ± 0.4 L/min per m2,P < 0.001) and increase in systemic vascular resistance index (1901.4 ± 330.2 dynes.s/cm5. m2,P < 0.001) toward normal levels were observed. There was also a significant reduction in pulmonary artery pressure (12.65 ± 4.7 mmHg,P < 0.001) and no significant changes in the pulmonary vascular resistance index (141.6 ± 102.9 dynes.s/cm5.m2). Four days after DSRS,a non-significant increase in cardiac index (5.2 ± 0.76 L/min per m2) and systemic vascular resistance index (1389 ± 311 dynes.s/cm5.m2) was observed. There was also a non-significant increase in pulmonary artery pressure (19.84 ± 5.2 mmHg),right cardiac work index (1.38 ± 0.4 kg.m/m2) and right ventricular systolic work index (16.3 ± 6.3 g.m/m2),without significant changes in the pulmonary vascular resistance index (139.7 ± 67.8 dynes.s/cm5.m2). CONCLUSION: The hyperdynamic circulatory state observed in mansonic schistosomiasis was corrected by EGDS,but was maintained in patients who underwent DSRS. Similarly,the elevated mean pulmonary artery pressure was corrected after EGDS and maintained after DSRS. EGDS seems to be the most physiologic surgery for patients with schistosomal portal hypertension. | Roberto de Cleva Paulo Herman Luis Augusto Carneiro D’albuquerque Vincenzo Pugliese Orlando Luis Santarem William Abro Saad | 2007 | World Journal of Gastroenterology2007，13，41： | 9 |
| 9 | Hardfacing steel with nanostructured coatings of Stellite-6 by supersonic laser deposition显示文摘The ability to manufacture coatings is critical to engineering design. Many components require the application of additional layers toenhance mechanical properties and protect against hostile environments. Supersonic laser deposition (SLD) is a novel coating methodbased on cold spray (CS) principles. In this technique, the deposition velocities can be significantly lower than those required foreffective bonding in CS applications. The addition of laser heat energy permits a change in the thermodynamic experience of impactingparticles, thereby offering a greater opportunity for efficient bonding at lower velocities as compared with the CS process. The workreported in this paper demonstrates the ability of the SLD process to deliver hardfacing materials to engineering surfaces. Stellite-6 hasbeen deposited on low-carbon steel tubes over a range of process parameters to establish the appropriate target power and traversespeeds for the coating formation. The coating properties and parameters were examined to determine the primary characteristics andgrain structure size. Their morphology and performance were studied through optical microscopy, scanning electron microscope(SEM), X-ray diffraction, hardness measurements and wear testing. The results have shown that SLD is capable of depositing layers ofStellite-6, with properties that are superior to those of their conventionally manufactured counterparts. | Rocco Lupoi Andrew Cockburn Chris Bryan Martin Sparkes Fang Luo William O’Neill | 2012 | Light(Science & Applications)2012，1，1： | 8 |
| 10 | Macrophage inhibitory cytokine-1/growth differentiation factor-15 in premalignant and neoplastic tumours in a high-risk pancreatic cancer cohort显示文摘BACKGROUND Pancreatic cancer(PC)is a leading cause of cancer related mortality worldwide,with poor survival due to late diagnosis.Currently,biomarkers have limited use in early diagnosis of PC.Macrophage inhibitory cytokine-1 or growth differentiation factor-15(MIC-1/GDF15)has been implicated as a potential serum biomarker in PC and other malignancies.AIM To determine the role of MIC-1/GDF15 in detecting pre-malignant pancreatic lesions and neoplastic tumours in an asymptomatic high-risk cohort part of Australian Pancreatic Cancer Screening Program.METHODS A feasibility prospective single centre cohort study was performed.Participants recruited for yearly surveillance with endoscopic ultrasound(EUS)had serial fasting blood samples collected before EUS for MIC-1/GDF15,C-reactive protein and carbohydrate antigen 19-9.Patients were stratified into five groups based on EUS findings:Normal;pancreatic cysts,branch-duct intraductal papillary mucinous neoplasm;diffuse non-specific abnormalities;and neoplastic tumours.MIC-1/GDF15 serum levels were quantified using ELISA.Participants in whom EUS demonstrated abnormalities but not malignancy were closely followed up with magnetic resonance imaging(MRI)or computed tomography.RESULTS One hundred twenty participants were prospectively recruited from 2011-2018.Forty-seven participants(39.2%)had an abnormal EUS and five participants(4.2%)were diagnosed with neoplastic tumours,three by EUS(two pancreatic and one liver)and two by MRI/computed tomography(breast cancer,bladder cancer),which were performed for follow up of abnormal EUS.Baseline serum MIC-1/GDF15 was a significant predictor of neoplastic tumours on receiver operator characteristic curve analysis[area under curve(AUC)=0.814,P=0.023].Baseline serum MIC-1/GDF15 had moderate predictive capacity for branch-duct intraductal papillary mucinous neoplasm(AUC=0.644)and neoplastic tumours noted on EUS(AUC=0.793),however this was not significant(P=0.188 and 0.081 respectively).Serial serum MIC-1/GDF15 did not demonstrate a significant percentage change between a normal and abnormal EUS(P=0.213).Median baseline MIC-1/GDF15 was greater in those with neoplastic tumours(Median=1039.6,interquartile range=727.0-1977.7)compared to those diagnosed with a benign lesion(Median=570.1,interquartile range=460.7-865.2)on EUS and MRI(P=0.012).CONCLUSION In this pilot study MIC-1/GDF15 has predictive capacity for neoplastic tumours in asymptomatic individuals with a genetic predisposition for PC.Further imagining may be warranted in patients with abnormal EUS and raised serum MIC-1/GDF15.Larger multicentric prospective studies are required to further define the role of MIC-1/GDF15 as a serological biomarker in pre-malignant pancreatic lesions and neoplastic tumours. | Robert Sean O’Neill Sam Emmanuel David Williams Alina Stoita | 2020 | World Journal of Gastroenterology2020，26，14： | 8 |
| 11 | 基于自适应化学理论甲烷预混燃烧的非主量成分的数值计算显示文摘麻省理工学院的Green教授提出了自适应化学理论(AdapChem)的概念。它采用相容分割法将守恒方程划分为化学方程和流动方程两个有机的部分。根据反应条件的不同,这种方法分别使用多个简化化学反应模型,而非复杂的详细基元反应机理进行区域内的数值模拟。它提供了在保证化学精度条件下,避免效率浪费的一条有效途径。针对CH4/空气预混火焰,应用自适应化学理论对其燃烧行为进行了合理的重现,并对几种重要的非主量成分进行了预测,得到了较为理想的模拟结果。 | 乔瑜 徐明厚 Viriato Semio William H.Green | 2005 | 中国电机工程学报2005，25，13： | 8 |
| 12 | 艾滋病的治疗与控制显示文摘感染人类免疫缺陷病毒(HIV)会造成免疫系统致命的进行性的破坏,导致各种被定义为获得性免疫缺陷综合征的机会性感染的发生.HIV感染有CD4表达的细胞,这是主要的病毒受体,见于辅助T淋巴细胞和单核/巨噬细胞.HIV原发感染常引起急性的病毒综合征,表现为发热、皮疹、腹泻和不适,伴有极高水平的血循环病毒水平,在淋巴结、脑和其它储存单位中发生感染.急性期的终结以特异性的HIV免疫应答为标志,包括HIV抗体的出现,对抗体的检测被用于诊断试验.随后的慢性而隐匿的病变期通常没有症状.病毒血症低下但始终存在,在数年的病程中CD4-;T细胞逐渐耗竭.随着病变的加重,CD4-;T细胞会加速丢失,并伴有循环病毒的增多,后者可用血浆HIV RNA检测加以量化(病毒载量).CD4+;T细胞降低至200个/mm3以下时可伴有各种机会性感染的出现.即使没有可确诊为AIDS的疾病出现,CD;T细胞计数低于200个/mm3也可考虑诊断为AIDS. | William A O’Brien | 2001 | 中国性病艾滋病防治2001，7，1： | 7 |
| 13 | 基于自适应化学理论的复杂CH_4燃烧模拟显示文摘麻省理工学院化工系的Green教授提出了自适应化学理论AdapChem的概念。这种方法根据反应条件的不同,分别使用多个简化化学反应模型而非复杂的详细基元反应模型进行区域内的数值模拟。该法提供了在保证化学精度条件下,避免效率浪费的一条有效途径。然而,为了完善AdapChem,引入以往没有考虑过的辐射模型是有必要的。为此,该文使用的是离散坐标法并对复杂CH4空气火焰进行了模拟,得到了较为理想的结果。 | 乔瑜 徐明厚 徐晓光 Pisi Lu Viriato Semi■o William H.Green | 2004 | 中国电机工程学报2004，24，2： | 7 |
| 14 | Endoscopic balloon catheter dilatation via retrograde or static technique is safe and effective for cricopharyngeal dysfunction显示文摘AIM To evaluate the safety and efficacy of upper esophageal sphincter(UES) dilatation for cricopharyngeal(CP) dysfunction. To determine if:(1) indication for dilatation; or(2) technique of dilatation correlated with symptom improvement.METHODS All balloon dilatations performed at our institution from over a 3-year period were retrospectively analyzed for demographics, indication and dilatation site. All dilatations involving the UES underwent further review to determine efficacy, complications, and factors that predict success. Dilatation technique was separated into static(stationary balloon distention) and retrograde(brusque pull-back of a fully distended balloon across the UES).RESULTS Four hundred and eighty-eight dilatations were reviewed. Thirty-one patients were identified who underwent UES dilatation. Median age was 63 years(range 27-81)and 55% of patients were male. Indications included dysphagia(28 patients), globus sensation with evidence of UES dysfunction(2 patients) and obstruction to echocardiography probe with cricopharyngeal(CP)bar(1 patient). There was evidence of concurrent oropharyngeal dysfunction in 16 patients(52%) and a small Zenker's diverticula(≤ 2 cm) in 7 patients(23%). Dilator size ranged from 15 mm to 20 mm. Of the 31 patients, 11 had dilatation of other esophageal segments concurrently with UES dilatation and 20 had UES dilatation alone.Follow-up was available for 24 patients for a median of 2.5 mo(interquartile range 1-10 mo), of whom 19 reported symptomatic improvement(79%). For patients undergoing UES dilatation alone, follow-up was available for 15 patients, 12 of whom reported improvement(80%).Nineteen patients underwent retrograde dilatation(84%response) while 5 patients had static dilatation(60%response); however, there was no significant difference in symptom improvement between the techniques(P = 0.5).Successful symptom resolution was also not significantly affected by dilator size, oropharyngeal dysfunction,Zenker's diverticulum, age or gender(P > 0.05). The only complication noted was uvular edema and a shallow ulcer after static dilatation in one patient, which resolved spontaneously and did not require hospital admission.CONCLUSION UES dilatation with a through-the-scope balloon by either static or retrograde technique is safe and effective for the treatment of dysphagia due to CP dysfunction. To our knowledge, this is the first study evaluating retrograde balloon dilatation of the UES. | Vinay Chandrasekhara Joyce Koh Lakshmi Lattimer Kerry B Dunbar William J Ravich John O Clarke | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，4： | 6 |
| 15 | LRP6 in mesenchymal stem cells is required for bone formation during bone growth and bone remodeling显示文摘Lipoprotein receptor-related protein 6(LRP6) plays a critical role in skeletal development and homeostasis in adults. However, the role of LRP6 in mesenchymal stem cells(MSCs), skeletal stem cells that give rise to osteoblastic lineage, is unknown. In this study, we generated mice lacking LRP6 expression specifically in nestin1MSCs by crossing nestin-Cre mice with LRP6floxmice and investigated the functional changes of bone marrow MSCs and skeletal alterations. Mice with LRP6 deletion in nestin1cells demonstrated reductions in body weight and body length at 1 and 3 months of age. Bone architecture measured by microCT(mCT) showed a significant reduction in bone mass in both trabecular and cortical bone of homozygous and heterozygous LRP6mutant mice. A dramatic reduction in the numbers of osteoblasts but much less significant reduction in the numbers of osteoclasts was observed in the mutant mice. Osterix1osteoprogenitors and osteocalcin1osteoblasts significantly reduced at the secondary spongiosa area, but only moderately decreased at the primary spongiosa area in mutant mice. Bone marrow MSCs from the mutant mice showed decreased colony forming, cell viability and cell proliferation. Thus, LRP6 in bone marrow MSCs is essential for their survival and proliferation, and therefore, is a key positive regulator for bone formation during skeletal growth and remodeling. | Changjun Li Bart O Williams Xu Cao Mei Wan | 2014 | Bone Research2014，2，1： | 6 |
| 16 | Archaea and the human gut:New beginning of an old story显示文摘Methanogenic archaea are known as human gut inhabitants since more than 30 years ago through the detection of methane in the breath and isolation of two methanogenic species belonging to the order Methanobacteriales,Methanobrevibacter smithii and Methanosphaera stadtmanae.During the last decade,diversity of archaea encountered in the human gastrointestinal tract(GIT)has been extended by sequence identification and culturing of new strains.Here we provide an updated census of the archaeal diversity associatedwith the human GIT and their possible role in the gut physiology and health.We particularly focus on the still poorly characterized 7th order of methanogens,the Methanomassiliicoccales,associated to aged population.While also largely distributed in non-GIT environments,our actual knowledge on this novel order of methanogens has been mainly revealed through GIT inhabitants.They enlarge the number of final electron acceptors of the gut metabolites to mono-di-and trimethylamine.Trimethylamine is exclusively a microbiota-derived product of nutrients(lecithin,choline,TMAO,L-carnitine)from normal diet,from which seems originate two diseases,trimethylaminuria(or Fish-Odor Syndrome)and cardiovascular disease through the proatherogenic property of its oxidized liver-derived form.This therefore supports interest on these methanogenic species and its use as archaebiotics,a term coined from the notion of archaea-derived probiotics. | Nadia Gaci Guillaume Borrel William Tottey Paul William O’Toole Jean-Fran?ois Brugère | 2014 | World Journal of Gastroenterology2014，20，43： | 5 |
| 17 | Metal-assisted chemical etching of silicon and the behavior of nanoscale silicon materials as Li-ion battery anodes显示文摘这评论在硅的帮助金属的化学蚀刻构画出开发和最近的进步,总结许多基本、创新的过程并且蚀刻形成大量 nanoscale 硅结构的方法。,为 Li 离子电池的阳极也是的硅的使用考察了因素象电影厚度那样,做, alloying,和他们对可逆 lithiation 进程的反应关于电池房间性能被总结并且讨论。在在 Li 离子电池改进基于硅的阳极的表演的最近的进展也被讨论。当 Li 离子电池阳极被构画出,许多 nanostructured 硅结构的使用由许多不同方法形成了,特别地集中于集体装载,核心壳结构,传导性的添加剂,和另外的参数的影响。电气化学的反应和硅阳极的房间性能上的孔,掺杂物类型,和做的水平的影响基于最近的调查结果被详细说明。硅和相关材料的未来上的观点,和他们为经由几电气化学的机制的精力存储的组合、结构的修正,也被提供。 | William McSweeney | 2015 | Nano Research2015，8，5： | 5 |
| 18 | 甲烷预混火焰自适应化学理论模拟及其与试验的比较显示文摘通常实际湍流火焰中不同燃烧区域的化学反应特性大不相同,且辐射在热传递过程中扮演了非常重要的角色。该文采用辐射模型离散坐标DO法来完善自适应化学理论。基于详细化学反应机理,在不同区域使用不同的简化反应模型来进行化学项的求解。针对甲烷,空气预混火焰,该文对其燃烧行为进行了合理的重现,考虑辐射模型之后的计算结果与试验结果吻合得更好。 | 乔瑜 徐明厚 VIRIATO SEMI(A|~)O WILLIAM H.GREEN | 2005 | 中国电机工程学报2005，25，19： | 5 |
| 19 | Characteristics of Stellite 6 Deposited by Supersonic Laser Deposition Under Optimized Parameters显示文摘Stellite 6 powders were deposited on low carbon steel using SLD (supersonic laser deposition) under optimized parameters. The structure, line scan of elements and porosity of coating were examined and analyzed using SEM (scanning electron microscope), OM (optical microscope) and XRD (X-ray diffraction). The adhesion strength between coating and substrate was tested by PAT-ADHESION/TENSILE and E900STM adhesive. The results showed the deposition characteristics of optimized coating with N2 at a pressure of 3.0 MPa, a temperature of 450 ℃ and a laser power of 1.5 kW were compared with those of Stellite 6 coating deposited by the HVOF (high velocity oxygen fuel). | LUO Fang Lupoi Rocco Cockburn Andrew Sparkes Martin O'neill William YAO Jian-hua | 2013 | Journal of Iron and Steel Research(International)2013，20，2： | 4 |
| 20 | Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblasts显示文摘The accumulation and aggregation of alpha-synuclein(α-syn)in several tissue including the brain is a major pathological hallmark in Parkinson’s disease(PD).In this study,we show that α-syn can be taken up by primary human cortical neurons,astrocytes and skin-derived fibroblasts in vitro.Our findings that brain and peripheral cells exposed to α-syn can lead to impaired mitochondrial function,leading to cellular degeneration and cell death,provides additional evidence for the involvement of mitochondrial dysfunction as a mechanism of toxicity of α-syn in human cells. | Nady Braidy Wei-Ping Gai Ying Hua Xu Perminder Sachdev Gilles J Guillemin Xing-Mai Jiang J William O Ballard Martin P Horan Zhi Ming Fang Beng H Chong Daniel Kam Yin Chan | 2013 | Translational Neurodegeneration2013，2，1： | 4 |
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