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| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 2 | Incidence of clinically diagnosed vertebral fractures: a population - based study in Rochester, Minnesota, 1985 - 1989显示文摘 | Cooper C A tkinson E J O' Fallon WM | 1992 | J Bone Miner Res1992，7，3： | 1 |
| 3 | A retrospective study of the effects of pelvic irradiation for gynecological cancer on anorectal function显示文摘 | Yeoh E Sun WM Russo A | 1996 | Int J Radiat Oncol Biol Phys1996，35，5： | 1 |
| 4 | The meaning of hope from the perspective of Chinese advanced cancer patients in Hong Kong显示文摘 | Mok E Lam WM Chan LN | 2010 | Int J Palliat Nurs2010，16，6： | 1 |
| 5 | Modulations in cerebral hemodynamics under three response requirements while solving language based problems:a transcranial Doppler study显示文摘 | Varnadore A E Roberts AE McKinney WM | 1997 | Neuropsychologia1997，35，： | 1 |
| 6 | Does sleep depriva-tion alter functional EEG networks in children with focal epilep sy? 显示文摘 | van Diessen E Otte WM Braun KP | 2014 | Front Syst Neurosci2014，29，5： | 1 |
| 7 | Tne FK506- binding protein 25 functionally associates with histone deacetylases and with transcription factor YY1显示文摘 | Yao YL Seto E | 2001 | EMBO J2001，20，17： | 1 |
| 8 | Effects of comprehensive lifestyle modification on diet, weight, physical fitness, and blood pressure control: 18-month results of a randomized trial 显示文摘 | Ehner PJ Obarzanek E Vollmer WM | 2006 | Ann Intern Med2006，144，7： | 1 |
| 9 | Two-photon fluorescence mi- croscopy of laurdan generalized polarization domains in model and natural membranes显示文摘 | Parasassi T Gratton E Yu WM | 1997 | Biophys J1997，72，6： | 1 |
| 10 | Interleukin-2-mediated elimination of thd p27kipl cyclin-dependent kinase inhibitor prevented by rapamycin显示文摘 | Nourse J Firpo E Flanagan WM | 1994 | Nature1994，372，6506： | 1 |
| 11 | Fetal monkey surfac- tants after intra-amniotic or maternal administration of betamethasone and thyroid hormone 显示文摘 | Gilbert WM Eby-Wilkens E Plopper C | 2001 | Obstetrics and Gynecology2001，，98： | 1 |
| 12 | Lunar influences on the reproductive cycle in women 显示文摘 | Cutler WB Schleidt WM Friedmann E | 1987 | Hum Biol1987，59，6： | 1 |
| 13 | Effects of comprehensive lifestyle modification on diet,weight,physical fit-ness,and blood pressure control:18-month results of a randomized trial显示文摘 | Elmer PJ Obarzanek E Vollmer WM | 2006 | Ann Intern Med2006，144，7： | 1 |
| 14 | Combination of SELDI-TOF-MS and data mining provides early-stage response prediction for rectal tumors undergoing multimodal neoadjuvant therapy显示文摘 | Smith FM Gallagher WM Fox E | 2007 | Ann Surg2007，245，2： | 1 |
| 15 | Interleukin- 2-mediated elimination of the p27Kipl cyclin dependent kinase inhibitor prevented by rapamyein 显示文摘 | Nourse J Firpo E Flanagan WM | 1994 | Nature1994，372，6506： | 1 |
| 16 | Human gamma delta T cells:a lymphoid lineage capable of professional phagocytosis显示文摘 | Wu Y Wu W Wong WM Ward E Thrasher AJ Goldblatt D Osman M Digardz P Canaday DH Gustafsson K | 2009 | J Immunol2009，183，9： | 1 |
| 17 | Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin 显示文摘 | Nourse J Firpo E Flanagan WM | 1994 | Nature1994，372，： | 1 |
| 18 | Influence of nitrogen and bagging on fruit quality and mineral concentrations of BC-2 Fuji apple显示文摘 | Fallahi E Colt WM Baird CR | 2001 | Hort Technology2001，11，3： | 1 |
| 19 | Incidence of clinically diagnosed vertebral fractures: a population-based study inPochester, Minnesota, 1985-1989显示文摘 | Cooper C Atkinson E J O Fallon WM | 1992 | J Bone Miner Res1992，7，： | 1 |
| 20 | Twenty-year outcome for individuals with autism and average or near average cognitive abilities显示文摘 | Farley MA McMahon WM Fombonne E | 2009 | Autism Res2009，2，2： | 1 |
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