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| 1 | Significance of an additional unenhanced scan in computed tomography angiography of patients with suspected acute aortic syndrome显示文摘AIM To assess potential benefits of an additional unenhanced acquisition in computed tomography angiography(CTA) in patients with suspected acute aortic syndrome(AAS).METHODS A total of 103 aortic CTA(non-electrocardiography-gated, 128 slices) performed due to suspected AAS were retrospectively evaluated for acute aortic dissection(AAD), intramural hematoma(IMH), or penetrating aortic ulcer(PAU). Spiral CTA protocol consisted of an unenhanced acquisition and an arterial phase. If AAS was detected, a venous phase(delay, 90 s) was added. Images were evaluated for the presence and extent of AAD, IMH, PAU, and related complications. The diagnostic benefit of the unenhanced acquisition was evaluated concerning detection of IMH.RESULTS Fifty-six(30% women; mean age, 67 years; median, 68 years) of the screened individuals had AAD or IMH. A triphasic CT scan was conducted in 76.8%(n =43). 56% of the detected AAD were classified as Stanford type A, 44% as Stanford type B. 53.8% of the detected IMH were classified as Stanford type A, 46.2% as Stanford type B. There was no significant difference in the involvement of the ascending aorta between AAD and IMH(P = 1.0) or in the average age between AAD and IMH(P = 0.548), between Stanford type A and Stanford type B in general(P = 0.650) and between Stanford type A and Stanford type B within the entities of AAD and IMH(AAD: P = 0.785; IMH: P = 0.146). Only the unenhanced acquisitions showed a significant density difference between the adjacent lumen and the IMH(P = 0.035). Subadventitial hematoma involving the pulmonary trunk was present in 5 patients(16%) with Stanford A AAD. The difference between the median radiation exposure of a triphasic(2737 mGy*cm) compared to a biphasic CT scan(2135 mGy*cm) was not significant(P = 0.135).CONCLUSION IMH is a common and difficult to detect entity of AAS. An additional unenhanced acquisition within an aortic CTA protocol facilitates the detection of IMH. | Nikolaos Panagiotopoulos Felix Drüschler Martin Simon Florian M Vogt Sebastian Wolfrum Steffen Desch Doreen Richardt Jorg Barkhausen Peter Hunold | 2018 | World Journal of Radiology2018，10，11： | 2 |
| 2 | Apolipoprotein M is required for preβ-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis显示文摘 | Wolfrum C Poy MN Stoffel M | 2005 | Nat Med2005，11，4： | 1 |
| 3 | Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis显示文摘 | WOLFRUM C POY M N STOFFEL M | 2005 | Nat Med2005，11，： | 1 |
| 4 | Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis显示文摘 | Wolfrum C Poy MN Stoffel M | 2005 | Nat Med2005，11，4： | 1 |
| 5 | 显示文摘 | Wolfrum E J Huang J Blake D M | 2002 | Environmental Scientific Technology2002，36，： | 1 |
| 6 | Calcitonin gene related peptide mediates cardioprotection by remote preconditioning显示文摘 | Wolfrum S Nienstedt J Heidbreder M | | 0，，13： | 1 |
| 7 | Apolipoprotein M is required for pre β- HDL formation and cholesterol efflux to HDL and protects against atherosclerosis 显示文摘 | Wolfrum C Poy MN Stoffel M | 2005 | Nat Med2005，11，4： | 1 |
| 8 | Calcitonin gene related peptide mediates cardioprotection by remote precondi- tioning 显示文摘 | Wolfrum S Nienstedt J Heidbreder M | 2005 | Regul Pept2005，127，13： | 1 |
| 9 | Metal oxidesensor arrays for the detection,differentiation,and quantificationof volatile organic compounds at sub-parts-per-millionconcentration levels 显示文摘 | Wolfrum E J Meglen R M Peterson D | 2006 | Sensors and Actuators B : Chemical2006，115，1： | 1 |
| 10 | The protective effect of A20 on atherosclerosis in apolipoprotein E-deficient mice is associated with reduced expression of NF-kappaB target genes 显示文摘 | Wolfrum S Teupser D Tan M | 2007 | Proc Natl Acad Sci U S A2007，104，18： | 1 |
| 11 | Metal oxide sensor arrays for the detection, differentiation, and quantification of volatile organic compounds at sub-parts-per-million concentration levels 显示文摘 | Wolfrum E J Meglen R M Peterson D | 2006 | Sensors and Actuators B : Chemical2006，115，1： | 1 |
| 12 | Apolipoprotein M is required for Prebeta-Hdl formation and cholesterol efflux to Hdl and protects against atherosclerosis显示文摘 | Wolfrum C Poy MN Stoffel M | 2005 | Nat Med2005，11，： | 1 |
| 13 | Phytanic acid is ligand and transcriptional activator of murine liver fatty acid binding protein显示文摘 | Wolfrum C Ellinghaus P Fobker M et at | 1999 | J Lipid Res1999，40，4： | 1 |
| 14 | Calcitonin gene related peptide mediates cardioprotection by remote preconditioning 显示文摘 | Wolfrum S Nienstedt J Heidbreder M | 2005 | Regulatory Peptides2005，12，7： | 1 |
| 15 | Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis显示文摘 | WOLFRUM C POY M N STOFFEL M | 2005 | Nat Med2005，11，： | 1 |
| 16 | Apolipoprotein M is required for pre β-HDL formation and cholesterol efflux to HDL and protects a- gainst atherosclerosis 显示文摘 | Wolfrum C Poy MN Stoffel M | 2005 | Nat Med2005，11，4： | 1 |
| 17 | Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis显示文摘 | Wolfrum C Poy MN Stoffel M | 2005 | Nat Med2005，11，4： | 1 |
| 18 | Apolipoprotein M is required for preβ-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis 显示文摘 | Wolfrum C Poy MN Stoffel M | 2005 | Nat Med2005，11，4： | 1 |
| 19 | Apolipoprotein M is required for preβ-HDL Formation and cholesterol efflux to HDL and protects against atherosclerosis显示文摘 | Wolfrum C Poy M N Stoffel M | 2005 | Nat Med2005，11，4： | 1 |
| 20 | Apolipoprotein M is required for preβ-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis显示文摘 | Wolfrum C Poy MN Stoffel M | 2005 | Nat Med2005，11，4： | 1 |
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