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| 1 | Isolation and Structure Elucidation of Autolytimycin, A New Compound Produced by Streptomyces Autolyticus JX-47显示文摘Autolytimycin 1 was isolated from the culture filtrate of Streptomyces autolyticus JX-47, together with two known compounds, lebstatin 2 and 17-O-demethyl-geldanamycin 3. These compounds showed the activities of anti-HSV-I. The structure of 1 was determined by spectral analysis. | Li, MG Wu, SH Zhao, LX Zhang, Q Li, WJ Cui, XL Xu, LH Wu, DG Jiang, CL | 2001 | Chinese Chemical Letters2001，12，10： | 10 |
| 2 | Seroepidemiology of Helicobacter pylori infection among asymptomatic Chinese children显示文摘INTRODUCTIONIncreasing data has demonstrated that Helicobacterpylori(H.pylori),a spiral gram negativebacterium,colonized in human stomach,can causetype B gastritis,is strongly associated withgastric and duodenal ulceration,and has beenimplicated in the causation of gastric carcinomaand mucosa-associated lymphoid tissue(MALT)lymphomas.It has been reported that there | Xu CD Chen SN Jiang SH Xu JY | 2000 | World Journal of Gastroenterology2000，6，5： | 6 |
| 3 | Establishment of an orthotopic transplantation tumor model of hepatocellular carcinoma in mice显示文摘AIM:To improve the outcome of orthotopic transplantation in a mouse model,we used an absorbable gelatin sponge(AGS) in nude mice to establish an orthotopic implantation tumor model.METHODS:MHCC-97L hepatocellular carcinoma(HCC)cells stably expressing the luciferase gene were injected into the subcutaneous region of nude mice.One week later,the ectopic tumors were harvested and transplanted into the left liver lobe of nude mice.The AGS was used to establish the nude mouse orthotopic implantation tumor model.The tumor suppressor gene,paired box gene 5(PAX5),which is a tumor suppressor in HCC,was transfected into HCC cells to validate the model.Tumor growth was measured by bioluminescence imaging technology.Semi-quantitative reverse transcription polymerase chain reaction(RT-PCR) and histopathology were used to confirm the tumorigenicity of the implanted tumor from the MHCC-97L cell line.RESULTS:We successfully developed an orthotopic transplantation tumor model in nude mice with the use of an AGS.The success rate of tumor transplantation was improved from 60% in the control group to 100% in the experimental group using AGS.The detection of fluorescent signals showed that tumors grew in all live nude mice.The mice were divided into 3 groups:AGS-,AGS+/PAX5-and AGS+/PAX5 +.Tumor size was significantly smaller in PAX5 transfected nude mice compared to control mice(P < 0.0001).These fluorescent signal results were consistent with observations made during surgery.Pathologic examination further confirmed that the tissues from the ectopic tumor were HCC.Results from RT-PCR proved that the HCC originated from MHCC-97L cells.CONCLUSION:Using an AGS is a convenient and efficient way of establishing an indirect orthotopic liver transplantation tumor model with a high success rate. | Gui-Jun Zhao Li-Xia Xu Eagle SH Chu Ning Zhang Jia-Yun Shen Alatangaole Damirin Xiao-Xing Li | 2012 | World Journal of Gastroenterology2012，18，47： | 4 |
| 4 | Hemangiopoietin, a novel human growth factor for the primitive cells of both hematopoietic and endothelial cell lineages显示文摘 | Liu,YJ Lu,SH Xu,B Yang,RC Ren,Q Liu,B Lu,M Yan,FY Han,ZB Han,ZC | 2005 | 中国生物学文摘2005，19，3： | 2 |
| 5 | Comparative studies on the antioxidant activities of nine common food legumes against copper-induced human low-density lipeprotein oxidation in vitro 显示文摘 | Xu BJ Yuan SH Chang SK | 2007 | J Food Sci2007，72，7： | 1 |
| 6 | Notch signaling auguments T cell responsiveness by enhancing CD25 expression显示文摘 | Adler SH Chiffoleau E Xu L | 2003 | J Immunol2003，171，6： | 1 |
| 7 | Synthesis, crystal structure, and insecticidal activities of highly congested hexahydroimidazo pyridine Derivatives: Effect of Conformation on Activities显示文摘 | Shao X Sh Xu Z P Zhao X F | 2010 | J Agric Food Chem2010，58，： | 1 |
| 8 | Quantitative MRI and X-ray analysis of disc degeneration and paraspinal muscle changes in degenerative spondylolisthesis显示文摘 | Wang GL Saugat BK Xu SH | 2015 | J Back Musculoskelet Rehabil2015，28，2： | 1 |
| 9 | Selection of patients for natural cycle in vitro fertilization combined with in vitro maturation of immature oocytes显示文摘 | Lim JH Yang SH Xu Y | 2009 | Fertil Steril2009，91，4： | 1 |
| 10 | Glucocorticoid receptor-mediated suppression of activator protein-1 activation and matrix metalloproteinase expression after spinal cord injury 显示文摘 | Xu J Kim GM Ahmed SH | 2001 | J Neurosci2001，21，1： | 1 |
| 11 | Synthesis of the adsorbent based on macroporous copolymer MA-DVB beads and its application in purification for the extracts from Ginkgo biloba leaves 显示文摘 | Ming-cheng Xu Zuo-qing Shi Rongfu Sh | 2000 | Reactive & Functional Polymers2000，43，3： | 1 |
| 12 | Structure and invitro bioachvity of htania-based films by micro-arc oxidation 显示文摘 | Hong SH Han Y Xu KW | 2003 | Surf Coat Technol2003，168，： | 1 |
| 13 | Clinicopathologic significance of mitotic arrest defective protein 2 over expression in hepatocellular carcinoma显示文摘 | Zhang SH Xu AM Chen XF | 2008 | Human Pathology2008，39，7： | 1 |
| 14 | Comparative effect of mebendazole, albendazole, tribendimidine, and praziquantel in treatment of rats infected with Clonorchis sinensis 显示文摘 | Xiao SH Xue J Xu LL | 2011 | Parasitol Res2011，108，3： | 1 |
| 15 | Preparative isolation of triterpenoids from Ganoderma lucidum by counter-current chromatography combined with pH-zone-refining 显示文摘 | Cheng CR Li YF Xu PP Feng RH Yang M Guan SH Guo DA | 2012 | Food Chem2012，130，： | 1 |
| 16 | Elevated C-reactive protein levels may be a predictor of persistent unfavourable symptoms in patients with mild traumatic brain injury: a preliminary study 显示文摘 | Su SH Xu W Li M | 2014 | Brain Behav Immun2014，38，5： | 1 |
| 17 | Isolation and identification of age-related DNA methylation markers for forensic age-prediction 显示文摘 | Yi SH Xu LC Mei K | 2014 | Forensic Sci Int Genet2014，11，： | 1 |
| 18 | Kimura disease: review of the lit- erature显示文摘 | Sun QF Xu DZ Pan SH etal | 2008 | Intern Med J2008，38，8： | 1 |
| 19 | A new directional weighted dedi- an filter for removal of randow-valued impulse noise显示文摘 | DONG Y Q XU SH F | 2007 | IEEE Signal Processing Lett2007，14，3： | 1 |
| 20 | Rheological,texture and sensory properties of low-fat mayonnaise with different fat mimetics 显示文摘 | Liu H Xu X M Guo Sh D | 2007 | LWT-Food Science and Technology2007，40，6： | 1 |
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