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1Effects of allicin on both telomerase activity and apoptosis in gastric cancer SGC-7901 cells显示文摘AIM: To investigate the effects of allicin on both telomeraseactivity and apoptosis in gastric cancer SGC-7901 cells.METHODS: The gastric cancer SGC-7901 adenocarcinomacells were treated with allicin and the cell cycle, inhibitoryrate, apoptosis, telomerase activity and morphologic changeswere studied by MTT assay, flow cytometry (FCM), TRAP-PCR-ELISA assay, light microscope, electron microscoperespectively. Results were compared with that of AZT (3′-Azido-3′-deoxythymidine).RESULTS: SGC-7901 cells were suppressed after exposureto allicin of 0.016 mg/ml, 0.05 mg/ml, and 0.1 mg/mi for48 h. Compared with the control, the difference wassignificant (P<0.05). Allicin could induce apoptosis of thecells in a dose-dependent and non-linear manner andincrease the proportion of cells in the G2/M phase. Comparedwith the control, the difference was significant in terms ofthe percentage of cells in the G2/M phase (P<0.05). Allicincould inhibit telomerase activity in a time-dependent anddose-dependent pattern. After exposure to allicin at 0.016mg/ml for 24 hours, SGC-7901 cells showed typicalmorphologic change.CONCLUSION: Allicin can inhibit telomerase activity andinduce apoptosis of gastric cancer SGC-7901 cells. Allicinmay be more effective than AZT.Li Sun Xu Wang Department of Oncology,Affiliated Hospital of Xuzhou Medical College,Xuzhou 221002,Jiangsu Province,China 2003World Journal of Gastroenterology2003,9,9:46
2Microcosmic analysis of ductile shearing zones of coal seams of brittle deformation domain in superficial lithosphere显示文摘The ductile shearing zones of coal seams in a brittle deformation domain in super-ficial lithosphere are put forward based on the study on bedding shearing and ductile rheology of coal seams. The macrocosmic and microcosmic characteristics include wrinkle fold, mymonitized zones and ductile planar structure of coal seams, etc., while the microcosmic characteristics may also include different optic-axis fabrics and the anisotropy of vitrinite reflectance as well as the change of chemical structure and organic geochemistry components. The forming mechanism is analyzed and the strain environment of ductile shearing zones of coal seams discussed. The result indicates that, in the superficial brittle deformation domain, the coal seams are easy to be deformed, resulting in not only brittle deformation but also ductile shearing deformation under the action of force. Because of simple shearing stress, the interlayer gliding or ductile rheology may take place between coal seams and wall rocks. Therefore, many ductile shearing zones come into being in superficial lithosphere (<5 km). The research on ductile shearing zone of brittle de-formation domain in superficial lithosphere is significant not only theoretically for the study of ductile shearing and ductile rheology of the lithosphere but also practically for the structural movement of coal seams, the formation and accumulation of coal-bed methane, and the preven-tion and harness of gas burst in coal mine.JU Yiwen1,2, WANG Guiliang2, JIANG Bo2 & HOU Quanlin1 1. Graduate School, Chinese Academy of Sciences, Beijing 100039, China 2. College of Mineral Resources and Geosciences, China University of Mining & Technology, Xuzhou 221008, China 2004Science China Earth Sciences2004,47,5:28
3ON JENSEN'S INEQUALITY FOR g-EXPECTATION显示文摘Briand et al. gave a counterexample showing that given g, Jensen's inequality for g-expectation usually does not hold in general This paper proves that Jensen's inequality for g-expectation holds in general if and only if the generator g (t, z) is super-homogeneous in z. In particular, g is not necessarily convex in z.JIANG LONG CHEN ZENGJING School of Mathematics and System Sciences, Shandong University, Jinan 250100, China. Department of Mathematics, China University of Mining and Technology, Xuzhou 221008, Jiangsu,China. E-mail: jianglong@math.sdu.edu.cn School of Mathematics and System Sciences, Shandong University, Jinan 250100, China. 2004Chinese Annals of Mathematics,Series B2004,25,3:26
4High precision slope deformation monitoring model based on the GPS/Pseudolites technology in open-pit mine显示文摘As the number and geometric intensity of visual satellites are susceptible to large slopes in open-pit mines, we propose integration of GPS/Pseudolites (PLs) positioning technology which can increase the number of visible satellites, strengthen the geometric intensity of satellites and provide a precision solution for slope deformation monitoring. However, the un-modeled systematic errors are still the main limiting factors for high precision baseline solution. In order to eliminate the un-modeled systematic error, the Empirical Mode Decomposition (EMD) theory is employed. The multi-scale decomposition and reconstruction architecture are defined here on the basis of the EMD theory and the systematic error mitigation model is demonstrated as well. A standard of the scale selection for the systematic error elimination is given in terms of the mean of the accumulated standardized modes. Thereafter, the scheme of the GPS/PLs baseline solution based on the EMD is suggested. The simulation and experiment results show that the precision factors (DOP) are reduced greatly when PLs is located suitably. The proposed scheme dramatically improves the reliability of ambiguity resolution and the precision of baseline vector after systematic error being eliminated, and provides an effective model for high precision slope deformation monitoring in open-pit mine.WANG Jianpeng, GAO Jingxiang, LIU Chao, WANG Jian School of Environment and Spatial Informatics, China University of Mining & Technology, Xuzhou 221008, China 2010Mining Science and Technology2010,20,1:25
5A promising new class of irradiation tolerant materials:Ti_2ZrHfV_(0.5)Mo_(0.2) high-entropy alloy显示文摘Recently, high-entropy alloys(HEAs) or multi-principal-element alloys with unprecedented physical,chemical, and mechanical properties, have been considered as candidate materials used in advanced reactors due to their promising irradiation resistant behavior. Here, we report a new single-phase bodycentered cubic(BCC) structured Ti_2 ZrHfV_(0.5)Mo_(0.2) HEA possessing excellent irradiation resistance, i.e.,scarcely irradiation hardening and abnormal lattice constant reduction after helium-ion irradiation,which is completely different from conventional alloys. This is the first time to report the abnormal XRD phenomenon of metallic alloys and almost no hardening after irradiation. These excellent properties make it to be a potential candidate material used as core components in next-generation nuclear reactors. The particular irradiation tolerance derives from high density lattice vacancies/defects.Yiping Lu Hefei Huang Xuzhou Gao Cuilan Ren Jie Gao Huanzhi Zhang Shijian Zheng Qianqian Jin Yonghao Zhao Chenyang Lu Tongmin Wang Tingju Li 2019Journal of Materials Science & Technology2019,35,3:23
6Metabolic analyses reveal different mechanisms of leaf color change in two purple-leaf tea plant (Camellia sinensis L.) cultivars显示文摘Purple-leaf tea plants,as anthocyanin-rich cultivars,are valuable materials for manufacturing teas with unique colors or flavors.In this study,a new purple-leaf cultivar“Zixin”(“ZX”)was examined,and its biochemical variation and mechanism of leaf color change were elucidated.The metabolomes of leaves of“ZX”at completely purple,intermediately purple,and completely green stages were analyzed using ultra-performance liquid chromatography quadrupole time of flight mass spectrometry(UPLC-QTOF-MS).Metabolites in the flavonoid biosynthetic pathway remained at high levels in purple leaves,whereas intermediates of porphyrin and chlorophyll metabolism and carotenoid biosynthesis exhibited high levels in green leaves.In addition,fatty acid metabolism was more active in purple leaves,and steroids maintained higher levels in green leaves.Saponin,alcohol,organic acid,and terpenoid-related metabolites also changed significantly during the leaf color change process.Furthermore,the substance changes between“ZX”and“Zijuan”(a thoroughly studied purple-leaf cultivar)were also compared.The leaf color change in“Zijuan”was mainly caused by a decrease in flavonoids/anthocyanins.However,a decrease in flavonoids/anthocyanins,an enhancement of porphyrin,chlorophyll metabolism,carotenoid biosynthesis,and steroids,and a decrease in fatty acids synergistically caused the leaf color change in“ZX”.These findings will facilitate comprehensive research on the regulatory mechanisms of leaf color change in purple-leaf tea cultivars.Jiazhi Shen Zhongwei Zou Xuzhou Zhang Lin Zhou Yuhua Wang Wanping Fang Xujun Zhu 2018Horticulture Research2018,5,1:22
7^(13)C NMR spectra of tectonic coals and the effects of stress on structural components显示文摘High-resolution 13C Nuclear Magnetic Resonance (NMR) spectra of different kinds of tectonic coals were obtained using the NMR (CP/MAS+TOSS) method. On the basis of this, after simulation synthesis and division of spectra, the relative contents of carbon functional groups were calculated. Combined with results of Ro, max, XRD testing and element analysis, stress effects on the composition of macromolecular structures in tectonic coals were studied further. The results showed that Ro, max was not only the important index for describing coal rank, but was also effective for estimating the stress effect of tectonic coals. Under tectonic stress ac- tion, Ro, max was the most direct indicator of the coal structure and chemical components. Changes in the stacking Lc of the coal basic structure unit (BSU) and La/Lc parameters could distinguish the temperature and stress effects on metamorphic-deformed environments, and re- flected the degree of structural deformation. Therefore, on the whole, Lc and La/Lc can be used to index of the degree of structural deformation of tectonic coals. In different metamorphic and de- formed environments, different kinds of tectonic coals are formed under structural stress. The changes in characteristics of the macromolecular structure and chemical composition are such that as the increase in structural deformation becomes stronger, from the brittle deformation coal to ductile deformation coal, the ratio of width at the half height of the aromatic carbon and ali- phatic carbon peaks (Hfa/Hfal ) was increased. As carbon aromaticity was raised further, carbon aliphaticity reduced obviously and different compositions of macromolecular structure appeared as a jump and wave pattern except for in wrinkle structure coal, which might result chiefly from stress effects on the macromolecular structure of different kinds of tectonic coals. The macro- moecular changes of wrinkle structure coal are reflected mainly on physical structure. In the metamorphic and deformed environments of the middle and high rank coals, different kinds of tectonic coals, when compared with the metamorphic and deformed environments of low rank coal, have a greater change in Hfa/Hfal, carbon aromaticity, carbon aliphaticity and a different composition of macromolecular structure. So these parameters can be used to estimate in- creases of coal rank, and to a certain degree, the stress effects on structural components of tectonic coals.JU Yiwen1,2, JIANG Bo1, HOU Quanlin2, WANG Guiliang1 & NI Shanqin2 1. College of Mineral Resource and Geosciences, China University of Mining and Technology, Xuzhou 221008, China 2. Laboratory of Computational Geodynamics, College of Geosciences, Graduate School of Chinese Academy of Sciences, Beijing 100049, China 2005Science China Earth Sciences2005,48,9:18
8Characteristics of acoustic emission signals in damp cracking coal rocks显示文摘A uniaxial load experiment on coal rocks at different stress rates was carried out, based on the characteristics of acoustic emission (AE) signals in cracking coal rocks, decomposition, de-noising and reconstruction for the AE signals through wavelet packet transform for solving the current problems created by the presence of noise in AE signals and the existing problems in AE signal processing. The results show that the various characteristics of AE signals in coal rocks cracking under different situations can be clearly reflected, after the AE signals are de-noised by the wavelet packet. Compared to dry coal rocks, the number of AE occurrences in damp coal rocks was significantly reduced, as well as the average amplitude. The number of AE occurrences in damp and dry coal rocks clearly increased with increases in the loading rate, but the largest amplitude of the AE signals in damp coal rocks has been reduced. There is no clear evidence of change in dry coal rocks.TANG Shoufeng, TONG Minming, HU Junli, HE Xinmin School of Information and Electrical Engineering, China University of Mining & Technology, Xuzhou 221008, China 2010Mining Science and Technology2010,20,1:17
9Event-related potentials in a Go/Nogo task of abnormal response inhibition in heroin addicts显示文摘Inhibitory control dysfunction is regarded as a core feature in addicts.The major objective of this study was to explore the time course of response inhibition in chronic heroin addicts and provide the neurophysiological evidence of their inhibitory control dysfunction.The amplitudes and latencies of ERP components were studied in fourteen heroin addicts(mean duration of heroin use being(13.54±5.71) years(Mean±SD),average abstinence being((4.67±6.44) months)) and fourteen matched healthy controls with a visual Go/Nogo task.Our results showed that heroin addicts demonstrated significantly larger Go-N2 amplitudes which results in a decreased N2 Go/Nogo effect,but no statistically significant differences were found between heroin addicts and controls in P3.The ERP data suggest that fronto-central areas of heroin addicts were impaired during the inhibition process(200-300 ms) and over-activated to targets.The impaired early process might reflect an abnormal conflict monitoring process in heroin addicts.These results consolidate the inhibitory control dysfunction hypothesis in chronic heroin users.YANG Bo1,YANG SuYong2,ZHAO Lun3,YIN LiuHua1,LIU Xu1& AN ShaSha1 1 Laboratory of Psychology,School of Sociology,China University of Political Science and Law,Beijing 102249,China 2 National Key Laboratory of Cognitive Neurosciences and Learning,Beijing Normal University,Beijing 100875,China 3 Institute of Language,Xuzhou Normal University,Xuzhou 221116,China 2009Science China(Life Sciences)2009,52,8:15
10Motion behavior of particles in air-solid magnetically stabilized fluidized beds for separation显示文摘In order to study the settling mechanism of particles in an air-solid magnetically stabilized fluidized bed(MSFB) for separation,we carried out free settling and quasi-zero settling tests on the tracing particles.The results show that the main resistance forces as the tracing particles settled in an air-solid MSFB were motion resistance force and yield force.The motion resistance and yield forces greatly hindered the free settling of the particles by greatly decreasing the acceleration for settling process of the particles.The acceleration decreased from 3022.62 cm/s 2 to zero in 0.1 s,and in the end,the particles stopped in the air-solid MSFB.The yield force on particles increased with increasing the magnetic field intensity,resulting in decrease of the quasi-zero settling displacement.However,the yield force on particles decreased with increasing the fluidized air velocity,leading to increase of the quasi-zero settling displacement.When the structure and operating parameters of the air-solid MSFB were set up,the yield stress on particles stopped in an air-solid MSFB was a function of diameter and density of particles.The settling displacements of equal diameter particles increased with increasing their densities,and the settling displacements of equal density particles increased with increasing their diameters.Song Shulei a,,Zhao Yuemin a,Luo Zhenfu a,Tang Ligang b a School of Chemical Engineering and Technology,China University of Mining & Technology,Xuzhou 221116,China b Coal Mining and Designing Department,Tiandi Science & Technology Company Co.Ltd.,Beijing 100013,China 2012International Journal of Mining Science and Technology2012,22,5:13
11Effects of Plasma Nitriding on Microstructure and Tribological Properties of CoCrMo Alloy Implant Materials显示文摘Medical forged CoCrMo alloy was treated by plasma nitriding process.The microstructures were characterized by 3Dprofiler,SEM and XRD.The tribological properties were investigated under lubrication of 25% bovine serum solution.Resultsshow that plasma nitriding is a promising process to produce thick,hard,and more wear resistant layers on the surface of CoCrMoalloy.All nitrided samples showed an important increase in the surface hardness due to the formation of harder CrN andCr2N phases with compact nano-crystalline structures.The typical hardness values of HV0.05 increased almost two times thanuntreated one.Under bovine serum lubrication,at low nitriding temperature the Coefficient of Friction (COF) of nitrided samplewas lower than that of untreated sample,but at high nitriding temperature the COF was almost the same as the untreated one.Compared with the untreated sample,the nitrided samples showed lower wear rates and higher wear resistance under differentnitriding temperatures.The adhesive wear is the main mechanism for untreated CoCrMo alloy and the wear mechanisms ofnitrided ones are the fatigue wear and slight adhesive wear.It is concluded that the improvement of wear resistance is ascribed tothe hard nitride formation of CrN and Cr2N phases at the nitrided surfaces.Qingliang Wang,Lei Zhang,Jiandong Dong School of Material Science and Engineering,China University of Mining & Technology,Xuzhou 221116,P.R.China 2010Journal of Bionic Engineering2010,7,4:12
12A new method for mining deformation monitoring with GPS-RTK显示文摘Based on ranging intersection theory, a new method which is simple and easy to operate was proposed for data collection in the mine surface deformation monitoring with GPS-RTK centering rod measurements. It can fully eliminate the inevitable shaking error and the vertical deflection, and to some extent weaken the multipath effect on the estimates of coordinates in a relatively short period of time, using high-frequency observations. The results show that three-dimensional coordinates with a height accuracy better than 1 cm, horizontal accuracy better than 2-4 cm can be achieved through only 15-30 s continuous observation by 20 Hz high-frequency and effectively improve the measurement accuracy and efficiency of RTK, fully satisfying the high-speed and high-precision data acquisition in mine surface subsidence deformation monitoring.GAO Jing-xiang1, 2, LIU Chao2, WANG Jian1, 2, LI Zeng-ke2, MENG Xiang-chao2 1. Key Laboratory for Land Environment and Disaster Monitoring of State Bureau of Surveying and Mapping, China University of Mining and Technology, Xuzhou 221116, China 2. School of Environment and Spatial Informatics, China University of Mining and Technology, Xuzhou 221116, China 2011中国有色金属学会会刊:英文版2011,21,S3:11
13Global existence and blow-up of solutions to a parabolic system with nonlocal sources and boundaries显示文摘This paper deals with a semi-linear parabolic system with nonlinear nonlocal sources and nonlocal boundaries.By using super-and sub-solution techniques,we first give the sufficient conditions that the classical solution exists globally and blows up in a finite time respectively,and then give the necessary and sufficient conditions that two components u and v blow up simultaneously.Finally,the uniform blow-up profiles in the interior are presented.Ling-hua KONG~(1+) Ming-xin WANG~(2,3) 1 Department of Applied Mathematics,Dalian University of Technology,Dalian 116024,China 2 Department of Mathematics,Southeast University,Nanjing 210018,China 3 Department of Mathematics,Xuzhou Normal University,Xuzhou 221116,China 2007Science China Mathematics2007,50,9:11
14Bergman kernels on generalized Hua domains显示文摘The Bergman kernel functions with explicit formulas of the generalized Hua domains are obtained. And the holomorphic automorphism group for each generalized Hua domain is also given.YIN Weiping and SU Jianbing(1. Department of Mathematics, Capital Normal University, Beijing 100037, China 2. Department of Mathematics, Xuzhou Normal University, Xuzhou 221116, China) 2002Progress in Natural Science:Materials International2002,12,12:11
15Jensen's Inequality for Backward Stochastic Differential Equations显示文摘在 g 上的 Lipschitz 假设和方形的 integrable 假设下面,如果并且仅当 g 独立于 y,作者证明 Jensen 的不平等为向后的随机的微分方程赞成发电机 g, g (t, 0 ) ≡ 0 并且 g 是超级的关于 z 同类。这结果为 g 期望在 Jensen 的不平等上概括已知的结果在[4, 7-9 ] 。Long JIANG Department of Mathematics, China University of Mining and Technology, Xuzhou 221008, Jiangsu, China School of Mathematical Sciences, Fudan University, Shanghai 200433, China School of Mathematics and System Sciences, Shandong University, Jinan 250100, China. 2006Chinese Annals of Mathematics,Series B2006,27,5:10
16Uniform blow-up profiles and boundary layer for a parabolic system with localized nonlinear reaction terms显示文摘This paper deals with the blow-up properties of the solution to a semilinear parabolic system with localized nonlinear reaction terms, subject to the null Dirichlet boundary condition. We first give sufficient conditions for that the classical solution blows up in the finite time, secondly give necessary conditions and a sufficient condition for that two components blow up simultaneously, and then obtain the uniform blow-up profiles in the interior. Finally we describe the asymptotic behavior of the blow-up solution in the boundary layer.LI Huiling & WANG Mingxin Department of Mathematics, Southeast University, Nanjing 210018, China Department of Mathematics, Xuzhou Normal University, Xuzhou 221116, China 2005Science China Mathematics2005,48,2:9
17Degradation of lignite model compounds by the action of white rot fungi显示文摘Three compounds modeled on the lignite structure were chosen for experimental degradation by different fungi strains. Culture conditions and extracellular enzyme activities were optimized. The growth curves of the strains were determined to study mycelium dry weight and protein content changes. Gas chromatography and infrared spectroscopy were used to detect changes of functional groups before and after the action of the fungi on the model compounds. Possible decomposition products and degrada-tion mechanisms were proposed. The research findings show that C. Versicolor and Golden Mushroom can grow in presence of the model compounds. The optimum culture conditions were a pH of 6.0, a carbon-nitrogen ratio of five and a Tween-80 concentration of 0.1%. Newly produced substances were found by gas chromatography. Infrared analysis showed that the model compounds degraded under the action of the microorganisms.DU Ying, TAO Xiuxiang, SHI Kaiyi, LI Yang School of Chemical Engineering and Technology, China University of Mining & Technology, Xuzhou 221000, China 2010Mining Science and Technology2010,20,1:9
18Effect of Preparation Methods on Mechanical Properties of PVA/HA Composite Hydrogel显示文摘Poly(vinyl alcohol) (PVA)/hydroxyapatite (HA) composite hydrogel specimens were prepared with 15% PVA and 1%,2%, 3%, 4% and 5% HA by repeated freezing-thawing. The tests of static and dynamic mechanical properties were carried out todiscuss the influence of different contents of HA and freezing-thawing cycles on the mechanical properties of PVA/HA compositehydrogel. The results of static mechanical tests showed that the PVA/HA composite hydrogel with 3% HA and ninefreezing-thawing cycles had excellent stress relaxation properties, higher relaxation ratio, lower stress equilibrium value andpresented better properties of creep and recovery. The results of dynamic mechanical test showed that the PVA/HA compositehydrogel with nine freezing-thawing cycles had higher storage modulus and loss modulus, so was the PVA/HA compositehydrogel with 3% HA.Dekun Zhang~1, Junjie Duan~1, Dagang Wang~2, Shirong Ge~2 1. School of Materials Science and Engineering, China University of Mining and Technology Xuzhou 221116, P. R. China 2. School of Mechanical and Electrical Engineering, China University of Mining and Technology, Xuzhou 221116, P. R. China 2010Journal of Bionic Engineering2010,7,3:8
19Transient temperature field of a friction pair in a HVD device of a belt conveyor显示文摘To show the distribution of a temperature field on a steel disk and to prolong the service life of a friction pair in a Hy-dro-Viscous Drive (HVD) device, a theoretical model of a transient temperature field was established, based on the theory of heat conduction. This theoretical model was solved using a finite element method. The results show that the surface temperature of the steel disk does not increase consistently as a function of the radius; the highest temperature appears short of the maximum radius. The relationship between the surface temperature and the mixed friction time is exponential. With a friction time of 15 s, the tem-perature reached 465.9 °C. Simultaneously, the internal thermal stress is larger than the yield stress of the material, causing a warping deformation of the steel disk. The largest axial deformation is 0.32 mm. The results of the experiment suggest that the de-formation is the same as that obtained from numerical simulation. Therefore, deformation of the steel disk must be considered dur-ing the study of the characteristics of a HVD.XIE Fangwei, HOU Youfu School of Mechanical and Electrical Engineering, China University of Mining & Technology, Xuzhou 221008, China 2010Mining Science and Technology2010,20,6:8
20Control strategy for an intelligent shearer height adjusting system显示文摘An intelligent shearer height adjusting system is a key technology for mining at a man-less working face. A control strategy for a shearer height adjusting system based on a mathematical model of the height adjusting mechanism is proposed. It considers the non-linearity and time variations in the control process and uses Dynamic Fuzzy Neural Networks (D-FNN). The inverse characteristics of the system are studied. An adaptive on-line learning and error compensation mechanism guarantees sys-tem real-time performance and reliability. Parameters from a German Eickhoff SL500 shearer were used with Matlab/Simulink to simulate a height adjusting control system. Simulation shows that the trace error of a D-FNN controller is smaller than that of a PID controller. Also, the D-FNN control scheme has good generalization and tracking performance, which allow it to satisfy the needs of a shearer height adjusting system.FAN Qigao, LI Wei, WANG Yuqiao, ZHOU Lijuan, YANG Xuefeng, YE Guo School of Mechanical & Electrical Engineering, China University of Mining & Technology, Xuzhou 221008, China 2010Mining Science and Technology2010,20,6:8
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