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| 1 | 阿德福韦双酯治疗拉米夫定耐药的慢性乙肝患者时出现的耐药问题显示文摘背景:阿德福韦双酯(ADV)是一种有效治疗野生型和耐拉米夫定乙肝病毒(HBV)的核苷酸类药物。在使用核苷酸类药物治疗慢性乙肝时,当治疗时间为48、96、144周时,耐ADV变异体出现的累积发生率分别为0、0.8-3%和0-5.9%。 | Yeon JE Yoo W Hong SP | 2006 | 中国处方药2006，，3： | 80 |
| 2 | 一些植物提取物对烟草甲虫生物活性的影响显示文摘测定了不同浓度的植物提取物在244、8和72 h后对烟草甲成虫的触杀毒力和驱避毒力。初步研究结果表明,筛选出的巴豆乙醇提取物、巴豆丙酮提取物、巴豆乙酸乙酯提取物、巴豆石油醚提取物、草乌丙酮提取物、草乌乙酸乙酯提取物、草乌石油醚提取物、驱虫草乙醇提取物、驱虫草丙酮提取物、川乌石油醚提取物、百部乙醇提取物、百部丙酮提取物、百部乙酸乙酯提取物、百部石油醚提取物、茵陈蒿乙醇提取物、茵陈蒿丙酮提取物等对烟草甲成虫有较好的触杀毒力;巴豆乙酸乙酯提取物、巴豆石油醚提取物、天南星科植物乙酸乙酯提取物、天南星科植物石油醚提取物、百部乙酸乙酯提取物、高良姜石油醚提取物、山鸡椒乙醇提取物、山鸡椒石油醚提取物等对烟草甲成虫有较好的驱避毒力。 | 赵海刚 宋纪真 谢剑平 Je Yeon Ho Jin Byung Rae 李建洪 | 2005 | 烟草科技2005，38，9： | 12 |
| 3 | 苏云金芽孢杆菌防治烟草害虫研究进展显示文摘综述了苏云金芽孢杆菌的发展概况、杀虫机理、在烟草害虫防治上的应用等,并讨论了苏云金芽孢杆菌在防治烟草害虫中存在的问题及其发展前景。 | 齐绪峰 宋纪真 JE YEON HO JIN BYUNG RAE 李建洪 | 2006 | 烟草科技2006，39，4： | 10 |
| 4 | 贮烟仓库中苏云金芽孢杆菌对烟草甲的杀灭活性显示文摘为研究苏云金芽孢杆菌(&)防治贮烟害虫的可行性,从全国7个主要卷烟厂的不同贮烟仓库中采集到不同类型的样品521份,采用醋酸钠抑制选择法从其中的225份样品中分离获得Bt952株,其分布率为100%,检出率为43.19%,用其中600株的发酵液对2~3龄烟草甲幼虫进行了初步毒力测定。结果表明,有18株分离株对烟草甲幼虫具有较高的生物活性,药后9d烟草甲幼虫的校正死亡率均达73%以上。 | 齐绪峰 宋纪真 谢剑平 JE YEON HO JIN BYUNG RAE 李建洪 | 2006 | 烟草科技2006，39，5： | 10 |
| 5 | Peroxisome proliferator-activated receptor-delta agonist ameliorated inflammasome activation in nonalcoholic fatty liver disease显示文摘AIM: To evaluate the inflammasome activation and the effect of peroxisome proliferator-activated receptors(PPAR)-δ agonist treatment in nonalcoholic fatty liver disease(NAFLD) models.METHODS: Male C57BL/6J mice were classified according to control or high fat diet(HFD) with or without PPAR-δ agonist(GW) over period of 12 wk [control, HFD, HFD + lipopolysaccharide(LPS), HFD + LPS + GW group]. Hep G2 cells were exposed to palmitic acid(PA) and/or LPS in the absence or presence of GW.RESULTS: HFD caused glucose intolerance and hepatic steatosis. In mice fed an HFD with LPS, caspase-1 and interleukin(IL)-1β in the liver were significantly increased. Treatment with GW ameliorated the steatosis and inhibited overexpression of pro-inflammatory cytokines. In Hep G2 cells, PA and LPS treatment markedly increased m RNA of several nucleotide-binding andoligomerization domain-like receptor family members(NLRP3, NLRP6, and NLRP10), caspase-1 and IL-1β. PA and LPS also exaggerated reactive oxygen species production. All of the above effects of PA and LPS were reduced by GW. GW also enhanced the phosphorylation of AMPK-α.CONCLUSION: PPAR-δ agonist reduces fatty acidinduced inflammation and steatosis by suppressing inflammasome activation. Targeting the inflammasome by the PPAR-δ agonist may have therapeutic implication for NAFLD. | Hyun Jung Lee Jong Eun Yeon Eun Jung Ko Eileen L Yoon Sang Jun Suh Keunhee Kang Hae Rim Kim Seoung Hee Kang Yang Jae Yoo Jihye Je Beom Jae Lee Ji Hoon Kim Yeon Seok Seo Hyung Joon Yim Kwan Soo Byun | 2015 | World Journal of Gastroenterology2015，21，45： | 9 |
| 6 | Room-temperature sputtered electrocatalyst WSe2 nanomaterials for hydrogen evolution reaction显示文摘The low-temperature physical vapor deposition process of atomically thin two-dimensional transition metal dichalcogenide(2D TMD) has been gaining attention owing to the cost-effective production of diverse electrochemical catalysts for hydrogen evolution reaction(HER) applications. We, herein, propose a simple route toward the cost-effective physical vapor deposition process of 2D WSe2 layered nanofilms as HER electrochemical catalysts using RF magnetron sputtering at room temperature(<27℃). By controlling the variable sputtering parameters, such as RF power and deposition time, the loading amount and electrochemical surface area(ECSA) of WSe2 films deposited on carbon paper can be carefully determined. The surface of the sputtered WSe2 films are partially oxidized, which may cause spherical-shaped particles. Regardless of the loading amount of WSe2, Tafel slopes of WSe2 electrodes in the HER test are narrowly distributed to be ~120–138 mV dec-1, which indicates the excellent reproducibility of intrinsic catalytic activity. By considering the trade-off between the loading amount and ECSA, the best HER performance is clearly observed in the 200 W-15 min sample with an overpotential of 220 mV at a current density of 10 mA cm-2. Such a simple sputtering method at low temperature can be easily expanded to other 2D TMD electrochemical catalysts, promising potentially practical electrocatalysts. | Jae Hyeon Nam Myeong Je Jang Hye Yeon Jang Woojin Park Xiaolei Wang Sung Mook Choi Byungjin Cho | 2020 | Journal of Energy Chemistry2020，29，8： | 3 |
| 7 | Meningioangiomatosis:MR imaging and pathological correlation in two cases显示文摘 | Kim WY Kim IO Kim WS Cheon JE Yeon KM | 2002 | Pediatr Radiol2002，32，： | 1 |
| 8 | Short segment HH: is it a clinically significant entity? 显示文摘 | Hyun JJ Kim JH Yeon JE | 2010 | J Neurogastroenterol Motil2010，6，1： | 1 |
| 9 | A novel organophosphorus hydrolase-based biosensor using mesoporous carbons and carbon black for the detection of organophosphate nerve agents显示文摘 | Joon Hwan Lee Jae Yeon Park Kyoungseon Min Hyung Joon Cha Suk Soon Choi Young Je Yoo | 2009 | Biosensors and Bioelectronics2009，，7： | 1 |
| 10 | Fanconi s syndrome associated with prolonged adefovir dipivoxil therapy in a hepatitis B virus patient显示文摘 | Jung YK Yeon JE Cho1]H | 2010 | Gut Liver2010，4，3： | 1 |
| 11 | Reduced expression of peroxisome proliferator-activated receptor-alpha may have an important role in the development of non-alcoholic fatty liver disease 显示文摘 | Yeon JE Choi KM Baik SH | 2004 | J Gastroenterol Hepatol2004，19，7： | 1 |
| 12 | Ethanol impairs insulin-stimulated neuronal survival in the developing brain:role of PTEN phospha-tase显示文摘 | Xu J Yeon JE Chang H | 2003 | J Biol Chem2003，278，26： | 1 |
| 13 | Ethanol impairs insulin - stimulated neuronal survival in the developing brain: Role of PTEN phosphatase 显示文摘 | Xu J Yeon JE Chang H | 2003 | J Biol Chem2003，278，26： | 1 |
| 14 | Therapeutic efficacy and stent patency of transhepatic portal vein stenting after surgery显示文摘AIM To evaluate portal vein(PV) stenosis and stent patency after hepatobiliary and pancreatic surgery, using abdominal computed tomography(CT).METHODS Percutaneous portal venous stenting was attempted in 22 patients with significant PV stenosis(> 50%)-after hepatobiliary or pancreatic surgery- diagnosed by abdominal CT. Stents were placed in various stenotic lesions after percutaneous transhepatic portography. Pressure gradient across the stenotic segment was measured in 14 patients. Stents were placed when the pressure gradient across the stenotic segment was > 5 mm Hg or PV stenosis was > 50%, as observed on transhepatic portography. Patients underwent followup abdominal CT and technical and clinical success, complications, and stent patency were evaluated.RESULTS Stent placement was successful in 21 patients(technical success rate: 95.5%). Stents were positioned through the main PV and superior mesenteric vein(n = 13), main PV(n = 2), right and main PV(n = 1), left and main PV(n = 4), or main PV and splenic vein(n = 1). Patients showed no complications after stent placement. The time between procedure and final follow-up CT was 41-761 d(mean: 374.5 d). Twenty stents remained patent during the entire follow-up. Stent obstruction-caused by invasion of the PV stent by a recurrent tumor- was observed in 1 patient in a follow-up CT performed after 155 d after the procedure. The cumulative stent patency rate was 95.7%. Small in-stent low-density areas were found in 11(55%) patients; however, during successive follow-up CT, the extent of these areas had decreased.CONCLUSION Percutaneous transhepatic stent placement can be safe and effective in cases of PV stenosis after hepatobiliary and pancreatic surgery. Stents show excellent patency in follow-up abdominal CT, despite development of small in-stent low-density areas. | Ung Bae Jeon Chang Won Kim Tae Un Kim Ki Seok Choo Joo Yeon Jang Kyung Jin Nam Chong Woo Chu Je Ho Ryu | 2016 | World Journal of Gastroenterology2016，22，44： | 1 |
| 15 | Fanconi's syndrome associated with prolonged adefovir dipivoxil therapy in a hepatitis B virus patient显示文摘 | Jung YK Yeon JE Choi JH | 2010 | Gut Liver2010，3，： | 1 |
| 16 | Fanconi's Syndrome Associated with Prolonged Adefovir Dipivoxil Therapy in a Hepatitis B Virus Patient显示文摘 | Jtmg YK Yeon JE Choi JH | 2010 | Gut Liver2010，4，3： | 1 |
| 17 | Technique for the early detection of drug-resistant HBV DNA during antiviral therapy显示文摘 | Yeon JE | 2008 | Intervirology2008，51，1： | 1 |
| 18 | Fanconi's syndrome associated with prolonged adefovir dipivoxil therapy in a hepatitis B virus patient 显示文摘 | Jung YK Yeon JE Choi JH | 2010 | Gut Liver2010，4，： | 1 |
| 19 | Resistance to adefovir dipivoxil in lamivadine resistant chronic hepatitis B patients treated with adefovir dipivoxil显示文摘 | Yeon JE Yoo W Hong SP | 2006 | Hepatology2006，55，10： | 1 |
| 20 | Bacillus thuringiensis isolates from Korean forest environments显示文摘 | Dae-Weon Lee Yeon Ho Je Young Ho Koh | 2012 | Journal of Asia-Pacific Entomology2012，，2： | 1 |
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