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| 1 | Oral health status in Sichuan Province: findings from the oral health survey of Sichuan, 2015–2016显示文摘To investigate oral health status in the residents of Sichuan Province, southwest China, a cross-sectional study was performed using the latest Oral Health Survey Basic Methods recommended by the World Health Organization. A multistage stratified random cluster-sampling method was used to enroll participants from the following three groups: children aged 3–5 years,adolescents aged 12 years, and people aged 65–74 years. In these three groups, the mean numbers of teeth that were affected by caries were 3.28, 0.86 and 5.13, respectively, resulting in a prevalence of 63.47%, 37.20% and 83.20%, respectively.Relative to the high rate of decayed teeth, the prevalence of fillings was very low in all age groups(0.97%, 7.24% and 5.43%,respectively). In the 12-year-old adolescent group, only 3.61% had good pit and fissure sealing. In addition, the rate of dental fluorosis was 24.80%, and the Community Fluorosis Index value was 0.39. In the elder group, the community periodontal index was2.92. The prevalence in the elderly of having lost at least one tooth was 75.54%. Additionally, 4.44% of these participants were edentulous. The incidence of dental prosthesis was 51.75%, the proportion with a removable partial denture, a fixed denture, full dentures, dental implants and an informal fixed bridge was 21.59%, 11.45%, 4.64%, 0 and 16.67%, respectively. In this study,8.2% of the elderly participants were affected by different types of oral mucosal lesions. Among such lesions, recurrent aphthous ulcers were most prevalent(2.69%) and oral lichen planuses were second(1.6%). The conclusion presented in this survey is that oral diseases, especially dental caries and periodontal disease, are frequent and common in Sichuan province, China. Moreover, the treatment rate is very low, and primary prevention and treatment options are therefore urgently needed in this population. | Wei Yin Ying-Ming Yang Hong Chen Xue Li Zhuo Wang Li Cheng Qiu-Dan Yin Hong-Zhi Fang Wei Fei Fang-Lin Mi Min-Hai Nie Tao Hu Xue-Dong Zhou | 2017 | International Journal of Oral Science2017，9，1： | 30 |
| 2 | BMI, WC, WHtR, VFI and BFI: Which Indictor is the Most Efficient Screening Index on Type 2 Diabetes in Chinese Community Population显示文摘Objective Obesity is a major risk factor for type 2 diabetes, many indexes can be used to describes obesity and predict diabetes. This research attempts to identify the best indicator of obesity to screening diabetes in Chinese population. Methods A cross-sectional data of 8121 subjects aged 35-60 years were included in this research belongs to the Diabetes Appropriate Technology Intervention Study. Anthropometric indicators including body weight, height, waist circumferences (WC), body fat index (BFI) and visceral fat index (VFI) and blood biochemical indicators after an overnight fast [fasting blood glucose, total cholesterol, high-density lipoprotein (HDL) cholesterol, and triacylglycerol] were measured. BMI (body mass index) and Weight to Height Ratio was calculated. Results Subjects with obesity had a higher risk of physician diagnosed diabetes (OR=2.50, 95% CI 1.83-3.43), new diagnosed diabetes (OR=4.23, 95% CI 2.91-6.15) and pre-diabetes (OR=1.75, 95% CI 1.31-2.34) compared to those with normal Body mass index (BMI). There was a significant trend of increased risk of all diabetes status with increased waist circumference (WC). The waist-to-height ratio (WHtR) yielded the most significant association with new diagnosed diabetes and physician diagnosed diabetes than other indices. Conclusion Central obesity is significantly correlated with diabetes. VFI was most correlated with pre-diabetes while WHtR is an efficient screening index than BMI and WC in Chinese community diabetes screening. | MI Sheng Quan YIN Peng HU Nan LI Jian Hong CHEN Xiao Rong CHEN Bo YAN Liu Xia ZHAO Wen Hua | 2013 | Biomedical and Environmental Sciences2013，26，6： | 20 |
| 3 | Portosplenomesenteric vein thrombosis in patients with early-stage severe acute pancreatitis显示文摘AIM To investigate the incidence and risk factors of portosplenomesenteric vein thrombosis(PSMVT) in the early stage of severe acute pancreatitis(SAP).METHODS Patients with SAP in a tertiary care setting from January 2014 to December 2016 were retrospectively reviewed. All contrast-enhanced computed tomography(CT) studies were reassessed and reviewed. Clinical outcome measures were compared between SAP patients with and without PSMVT in the early stage of the disease. Univariate and multivariate logistic regression analyses were sequentially performed to assess potential risk factors for the development of PSMVT in SAP patients. A receiver operating characteristic(ROC) curve was generated for the qualifying independent risk factors.RESULTS Twenty-five of the one hundred and forty(17.86%) SAP patients developed PSMVT 6.19 ± 2.43 d after acute pancreatitis(AP) onset. PSMVT was confirmed by contrast-enhanced CT. Multivariate stepwise logistic regression analyses showed that Balthazar's CT severity index(CTSI) scores [odds ratio(OR): 2.742; 95% confidence interval(CI): 1.664-4.519; P = 0.000], hypoalbuminemia(serum albumin level < 25 g/L)(OR: 32.573; 95%CI: 2.711-391.353; P = 0.006) and gastrointestinal wall thickening(OR: 4.367, 95%CI: 1.218-15.658; P = 0.024) were independent risk factors for PSMVT developed in patients with SAP. The area under the ROC curve for Balthazar's CTSI scores was 0.777(P = 0.000), the sensitivity was 52%, and the specificity was 93% at a cut-off value of 5.5.CONCLUSION High Balthazar's CTSI scores, hypoalbuminemia and gastrointestinal wall thickening are independent risk factors for PSMVT developed in the early stage of SAP. | Ling Ding Feng Deng Chen Yu Wen-Hua He Liang Xia Mi Zhou Xin Huang Yu-Peng Lei Xiao-Jiang Zhou Yin Zhu Nong-Hua Lu | 2018 | World Journal of Gastroenterology2018，24，35： | 20 |
| 4 | Effect of thermomechanical treatment on microstructure and properties of Cu-Cr-Zr-Ag alloy显示文摘The effects of thermomechanical treatment on the properties and microstructure of Cu-Cr-Zr alloy and Cu-Cr-Zr-Ag alloy were investigated. Ag addition improves the mechanical properties of the alloy through solid solution strengthening and brings a little effect on the electrical conductivity of the alloy. A new Cu-Cr-Zr-Ag alloy was developed, which has an excellent combination of the tensile strength, elongation, and electrical conductivity reaching 476.09 MPa, 15.43% and 88.68% IACS respectively when subjected to the optimum thermomechanical treatment, i.e., solution-treating at 920°C for 1 h, cold drawing to 96% deformation, followed by aging at 400°C for 3 h. TEM analysis re-vealed two kinds of finely dispersed precipitates of Cr and Cu4Zr. It is very important to use the mechanisms of solid solution strengthening, work hardening effect as well as precipitate pinning effect of dislocations to improve tensile strength of the alloy without adversely affecting its electrical conductivity. | XIE Haofeng MI Xujun HUANG Guojie GAO Baodong YIN Xiangqian LI Yanfeng | 2011 | Rare Metals2011，30，6： | 17 |
| 5 | Effect of Lycium barbarum Polysaccharides on the expression of endothelin-1 and its receptors in an ocular hypertension model of rat glaucoma显示文摘Lycium barbarum, a traditional Chinese anti-aging herb, has been shown to protect retinal ganglion cells (RGCs) in a rat chronic ocular hypertension (COH) model. Here, we investigated the expression of endothelin-1 (ET-1), a strong vasoconstrictor, and its receptors, ETA and ETB, in the COH model and assessed the effects of Lycium barbarum on the ET-1 axis. Elevated intraocular pressure (IOP) was induced in the right eye of SD rats using argon laser photocoagulation. (1) The expression of ET-1, ETA and ETB in normal and COH retinas was studied. (2) Some COH rats were fed daily with Lycium barbarum Polysaccharides (LBP) using 1 mg/kg or phosphate-buffered saline (PBS) for 3 weeks (started 1 week before photocoagulation). The effects of LBP on the expression of ET-1 and its receptors, ETA and ETB, in COH retina were evaluated. A semi-quantitative analysis of staining intensity was used to evaluate the expression levels of ET-1, ETA and ETB in retinal vasculature. We found that (1) Under COH condition, the immunoreactivity of ET-1 was increased in retina associated with an increase of ETB receptor immunoreactivity and a decrease of ETA receptor immunoreactivity. (2) After feeding COH rats with LBP, the expression of ET-1 was decreased with an increase of ETA expression and a decrease of ETB expression in the retina, especially in RGCs. (3) By comparing the staining intensity in the vasculature of COH retina in LBP-fed group with PBS-fed group, there was a decrease in the expression of ET-1 and ETA and an increase in ETB. In summary, ET-1 expression was up-regulated in the retina in COH model. LBP could decrease the expression of ET-1 and modulate the expression of its receptors, ETA and ETB, under the condition of COH. The neuroprotective effect of LBP on RGCs might be related to its ability to regulate the ET-1-mediated biological effects on RGCs and retinal vasculature. | Xue-Song Mi Kin Chiu Geoffrey Van Justin Wai Chung Leung Amy Cheuk Yin Lo SookjaKim Chung Raymond Chuen-Chung Chang Kwok-Fai So | 2012 | Neural Regeneration Research2012，7，9： | 14 |
| 6 | Lycium barbarum polysaccharides related RAGE and Aβ levels in the retina of mice with acute ocular hypertension and promote maintenance of blood retinal barrier显示文摘Our previous study verified the protective effects of Lycium barbarum polysaccharides(LBP)on retinal neurons and blood vessels in acute ocular hypertension(AOH)mice.To investigate the effect of LBP on the reactivity of retinal glial cells,an AOH mouse model was established in one eye by maintaining ocular hypertension of 90 mm Hg for 60 minutes.Either LBP solution(1 mg/kg)or phosphate-buffered saline was administrated to the mice by gavage daily,starting 7 days before the AOH insult and continuing until the mice were sacrificed for specimen collection on day 4 post-insult.After AOH insult,increased numbers of astrocytes and microglia were observed,together with decreased expression of the following glial cell biomarkers in the retinal ganglion cells of AOH mice:glial fibrillary acidic protein,glutamine synthetase,aquaporin-4,S-100 proteins,ionized calcium-binding adaptor molecule 1,amyloid precursor protein and receptor of advanced glycosylation end-products.After intervention with LBP,the above changes were significantly reduced.Remarkably,morphological remodeling of blood vessel-associated retinal astrocytes,marked by glial fibrillary acidic protein,was also observed.These results,taken together,suggest that LBP regulated the production of amyloid-βand expression of receptor of advanced glycosylation end-products,as well as mediating the activity of retinal glial cells,which may lead to the promotion of better maintenance of the blood-retinal barrier and improved neuronal survival in AOH insult.This study was approved by the Committee for the Use of Live Animals in Teaching and Research(approval No.CULTRA-#1664-08). | Xue-Song Mi Qian Feng Amy Cheuk Yin Lo Raymond Chuen-Chung Chang Sookja Kim Chung Kwok-Fai So | 2020 | Neural Regeneration Research2020，15，12： | 8 |
| 7 | Acellular ostrich corneal stroma used as scaffold for construction of tissue-engineered cornea显示文摘AIM:To assess acellular ostrich corneal matrix used as a scaffold to reconstruct a damaged cornea.· METHODS:A hypertonic saline solution combined with a digestion method was used to decellularize the ostrich cornea.The microstructure of the acellular corneal matrix was observed by transmission electron microscopy(TEM) and hematoxylin and eosin(H&E) staining.The mechanical properties were detected by a rheometer and a tension machine.The acellular corneal matrix was also transplanted into a rabbit cornea and cytokeratin 3 was used to check the immune phenotype.·RESULTS:The microstructure and mechanical properties of the ostrich cornea were well preserved after the decellularization process.In vitro,the methyl thiazolyl tetrazolium results revealed that extracts of the acellular ostrich corneas(AOCs) had no inhibitory effects on the proliferation of the corneal epithelial or endothelial cells or on the keratocytes.The rabbit lamellar keratoplasty showed that the transplanted AOCs were transparent and completely incorporated into the host cornea while corneal turbidity and graft dissolution occurred in the acellular porcine cornea(APC) transplantation.The phenotype of the reconstructed cornea was similar to a normal rabbit cornea with a high expression of cytokeratin 3 in the superficial epithelial cell layer.· CONCLUSION:We first used AOCs as scaffolds to reconstruct damaged corneas.Compared with porcine corneas,the anatomical structures of ostrich corneas are closer to those of human corneas.In accordance with the principle that structure determines function,a xenograft lamellar keratoplasty also confirmed that the AOC transplantation generated a superior outcome compared to that of the APC graft. | Xian-Ning Liu Xiu-Ping Zhu Jie Wu Zheng-Jie Wu Yong Yin Xiang-HuaXiao Xin Su Bin Kong Shi-Yin Pan Hua Yang Yan Cheng Na An Sheng-Li Mi | 2016 | International Journal of Ophthalmology(English edition)2016，9，3： | 6 |
| 8 | MiR-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1显示文摘糖尿病和许多另外的新陈代谢症候群是仔细与肥胖有关。揭示胖免职的内在的机制,越来越多的研究在 adipocytes 开发期间正在集中于 miRNAs 的功能。以前的研究 haveproved 那出 miR-15a/b 戏在多重生理的过程的重要角色;然而,他们的功能在 adipogenesisremain 期间不清楚。揭示这,我们在猪的 pre-adipocyte 在 adipogenesis 期间检测了 miR-15a/b 的表示侧面,并且发现那他们层次在 adipocyte 区别的早阶段增加了并且在白天 4 .Moreover 以后落下的表示,在猪的 pre-adipocytes 的 miR-15a/b 的在表示上支持了 adipocyte 区别, miR-15a/b 的类脂化合物 accumulation.Target 基因被预言并且检验,它表明 Forkhead 盒子蛋白质 O1 ( FoxO1 )是目标 geneof miR-15a/b 。表示水平由 miR-15a/b 在表示上引起了的 FoxO1 的抑制在 adipogenesis.Thus 上有积极效果,我们断定 miR-15a/b 经由镇压在猪的 pre-adipocyte 支持 adipogenesis FoxO1。 | Peiyue Dong Yin Mai Zhenyu Zhang Lin Mi Guofang Wu Guiyan Chu Gongshe Yang Shiduo Sun | 2014 | Acta Biochimica et Biophysica Sinica2014，46，7： | 6 |
| 9 | Muscarinic acetylcholine receptor M1 mediates prostate cancer cell migration and invasion through hedgehog signaling显示文摘自治神经系统贡献前列腺癌症增长和转移。然而,准确分子的机制仍然保持不清楚。在这研究, muscarinic 醋胆素受体 M1 (CHRM1 ) 表示在人的前列腺癌症织物数组幻灯片经由 immunohistochemical 分析被测量。PC-3, LNCaP,和 A549 房间与 pirenzepine 或 carbachol 被对待,并且房间迁居和侵略能力被评估。西方的弄污和量的即时 PCR 被执行测量 GLI 家庭锌手指 1 (GLI1 ) ,修正了 1 (PTCH1 ) ,并且声音的刺猬(嘘) 表示层次。CHRM1 的高表示在早阶段的人的前列腺癌症纸巾被发现。另外,选择 CHRM1 对手 pirenzepine 禁止了 PC-3, LNCaP,和 A549 房间移植和侵略,但是收缩筋 carbachol 支持了这三根房间线的迁居和侵略。发信号的 Muscarinic 能被刺猬发信号中继。CHRM1 通过表明小径的刺猬涉及前列腺癌症移植和侵略的规定的这些数据表演。 | Qing-Qing Yin Lin-Hui Xu Mi Zhang Chen Xu | 2018 | Asian Journal of Andrology2018，20，6： | 5 |
| 10 | Degradation of 2,2′,4,4′-tetrabromodiphenyl ether by Pycnoporus sanguineus in the presence of copper ions显示文摘The degradation of 2,2′,4,4′-tetrabromodiphenyl ether(BDE-47) by Pycnoporus sanguineus was investigated in order to explore the impact of the heavy metal Cu2+ on BDE-47 decomposition and the subsequent formation of metabolites, as well as to further elucidate the degradation mechanism of BDE-47. An increase in degradation rate from 18.63% to49.76% in the first four days and its stabilization at(51.26 ± 0.08)% in the following days of BDE-47 incubation were observed. The presence of Cu2+ at 1 and 2 mg/L was found to promote the degradation rate to 56.41% and 60.79%, respectively, whereas higher level of Cu2+(≥ 5 mg/L) inhibited the removal of BDE-47. The similar concentration effects of Cu2+ was also found on contents of fungal protein and amounts of metabolites. Both intracellular and extracellular enzymes played certain roles in BDE-47 transportation with the best degradation rate at 27.90% and 27.67% on the fourth and third day, individually. During the degradation of BDE-47, four types of hydroxylated polybrominated diphenyl ethers(OH-PBDEs), i.e., 6′-OH-BDE-47, 5′-OH-BDE-47, 4′-OH-BDE-17, 2′-OH-BDE-28, and two bromophenols, i.e., 2,4-DBP and 4-BP were detected and considered as degradation products. These metabolites were further removed by P. sanguineus at rates of 22.42%,23.01%, 27.04%, 27.96%, 64.21%, and 40.62%, respectively. | Meiqian Wang Hua Yin Hui Peng Mi Feng Guining Lu Zhi Dang | 2019 | Journal of Environmental Sciences2019，31，9： | 4 |
| 11 | Effects of electrode configuration on electroslag remelting process of M2 high-speed steel ingot显示文摘The electrode configuration determines the thermophysical field during the electroslag remelting(ESR) process and affects the final microstructure of the ingot. In this work, ingot with a diameter of 400 mm was prepared with two electrode configuration modes of single power ESR process, namely one electrode(OE) and two series-connected electrodes(TSCE). Finite element simulation was employed to calculate the electromagnetic field, flow field and temperature field of the ESR system. The results show that the temperature of the slag pool and the metal pool of the TSCE process is lower and more uniform than that of the OE process.The calculated temperature distribution of the ingot could be indirectly verified from the shape of the metal pool by the experiment. The experimental results show that the depth of the metal pool in the OE ingot is about 160 mm, while the depth of the TSCE ingot is nearly 40 mm shallower than that of the OE ingot. Microstructural comparisons indicate that coarse eutectic carbides are formed in the center of the OE ingot, whereas more even eutectic carbides appear in the center of the TSCE ingot. In general, compared with the OE process, the TSCE process is preferred to remelt high speed steel ingots. | Fu-xing Yin Yu Liang Zhi-xia Xiao Jian-hang Feng Zhi-bin Xie Yong-wang Mi | 2019 | China Foundry2019，16，2： | 3 |
| 12 | Recombinant proteins secreted from tissue-engineered bioartificial muscle improve cardiac dysfunction and suppress cardiomyocyte apoptosis in rats with heart failure显示文摘基于肌肉的基因治疗代表答应的背景设计织物的 bioartificial 为心疾病的治疗来临。试验性、临床的研究建议在心的 IGF-1 的蛋白质或 overexpression 施加的像胰岛素的生长 factor-1 (IGF-1 ) 的那个全身的政府心血管的功能上的有利效果。试图在心肌的梗塞(MI ) 和由在左冠的动脉或假冒的操作的 Sprague-Dawley rats.Methods 结扎跟随冠的动脉结扎的设计织物的 bioartificial 肌肉(欺骗) 交付人的 IGF-1 基因的潜在的治疗学的效果以后调查一个长期的阶段的这研究被执行。主要骨胳的 myoblasts 是 retrovirally 综合并且分泌 recombinant 的 transduced 人的像胰岛素的生长 factor-1 (rhIGF-1 ) ,和绿色荧光灯蛋白质(GFP ) ,并且进可植入的欺骗设计织物。经历了结扎的老鼠随机被分到 2 个组:MI-IGF 组(n=6 ) 和 MI-GFP 组(n=6 ) 。MI-IGF 组收到了秘密 rhIGF 欺骗(IGF 欺骗) 移植,和 MI-GFP 组收到了秘密 GFP 欺骗(GFP 欺骗) 移植。另一组老鼠担任了假冒的操作组,它随机也被分到 2 亚群:S-IGF 组(n=6 ) 和 S-GFP 组(n=6 ) 。S-IGF 组经历了 IGF-1-BAM 移植,并且 S-GFP 组经历了 GFP 欺骗移植。在二星期操作被执行以后, IGF-1-BAMs 和 GFP 欺骗皮下地被植入进 syngeneic 老鼠。在处理以后的四个星期, hemodynamics 被执行。IGF-1 被放射性免疫测定测量,然后老鼠被牺牲,室的样品受到 immunohistochemistry。反向的 transcriptase 聚合酶链反应(RT-PCR ) 被用来检验 bax 和 Bcl-2 的 mRNA 表示。TNF- 和 caspase 在心肌层的 3 表示被主要老鼠 myoblasts 是的西方的 blotting.Results 检验 retrovirally 分泌 rhlGF-1 的 transduced 并且进包含 postmitotic myofibers 的平行数组的可植入的欺骗设计织物。在 vitro,他们分泌了 hIGF 的一致层次(0.4-1.2 g 吗?? | RONG Shu-ling WANG Yong-jin WANG Xiao-lin LU Yong-xin WU Yin LIU Qi-yun MI Shao-hua XU Yu-lan | 2010 | Chinese Medical Journal2010，，24： | 3 |
| 13 | Nanovilli electrode boosts hydrogen evolution:A surface with superaerophobicity and superhydrophilicity显示文摘Although tremendous efforts have been paid on electrocatalysts toward efficient electrochemical hydrogen generation,breakthrough is still highly needed in the design and synthesis of wonderful non-precious-metal electrocatalyst.Herein,a nanovilli Ni2P electrode,which with superaerophobic and superhydropholic can significantly facilitate the mass and electron transfer was constructed via a facial morphology control strategy.Meanwhile,the substitution of sluggish oxygen evolution with urea oxidation,lowering the two-electrode cell voltage to only 1.48 volts to achieve a current density of 10 mA·cm^(-2).Thus,the as-constructed electrode achieves the operation of hydrogen generation by an AA battery.This work sheds new light on the exploration of other high-efficient electrocatalysts for hydrogen generation by using intermittent clean energy. | Yijun Yin Yan Tan Qiuyuan Wei Shucong Zhang Siqi Wu Qin Huang Feilong Hu Yan Mi | 2021 | Nano Research2021，14，4： | 3 |
| 14 | Microstructural evolution and properties of a Cu-Cr-Ag alloy during continuous manufacturing process显示文摘Microstructure evolution and properties of a Cu-Cr-Ag alloy during the continuous manufacturing process were investigated in detail by scanning electron microscopy(SEM)and transmission electron microscopy(TEM)in the study.The Cu-Cr-Ag alloy rod with uniform compositions is fabricated by upward continuous casting technology.Few of the Cr phases are observed in the ascast alloy.During the continuous extrusion process,the severe shear deformation and the dynamic aging occur.The average grain size of as-extruded alloy is much smaller than that of as-cast alloy.Both fcc and bcc Cr precipitates appear in the matrix.The interaction mode between dislocations and precipitates can be identified as Orowan bypass mode according to the TEM observations.The overall difference in the yield strength between as-cast and as-extruded Cu-Cr-Ag alloy is attributed to solid solution strengthening,grain refinement strengthening,precipitation hardening and working hardening. | Gao-Lei Xu Li-Jun Peng Guo-Jie Huang Hao-Feng Xie Zhen Yang Xue Feng Xiang-Qian Yin Xu-Jun Mi | 2021 | Rare Metals2021，40，8： | 3 |
| 15 | Abdominal Obesity and Its Attribution to All-cause Mortality in the General Population with 14 Years Follow-up:Findings from Shanxi Cohort in China显示文摘Objective This study aimed to assess the association of waist circumference(WC)with all-cause mortality among Chinese adults.Methods The baseline data were from Shanxi Province of 2002 China Nutrition and Health Survey.The death investigation and follow-up visit were conducted from December 2015 to March 2016.The visits covered up to 5,360 of 7,007 participants,representing a response rate of 76.5%.The Cox regression model and floating absolute risk were used to estimate hazard ratio and 95%floating CI of death by gender and age groups(≥60 and<60 years old).Sensitivity analysis was performed by excluding current smokers;participants with stroke,hypertension,and diabetes;participants who accidentally died;and participants who died during the first 2 years of follow-up.Results This study followed 67,129 person-years for 12.5 years on average,including 615 deaths.The mortality density was 916 per 100,000 person-years.Low WC was associated with all-cause mortality among men.Multifactor-adjusted hazard ratios(HR)were 1.60(1.35–1.90)for WC<75.0 cm and 1.40(1.11–1.76)for WC ranging from 75.0 cm to 79.9 cm.Low WC(<70.0 cm and 70.0–74.9 cm)and high WC(≥95.0 cm)groups had a high risk of mortality among women.The adjusted HRs of death were 1.43(1.11–1.83),1.39(1.05–1.84),and 1.91(1.13–3.22).Conclusion WC was an important predictor of death independent of body mass index(BMI).WC should be used as a simple rapid screening and predictive indicator of the risk of death. | ZHAI Yi REN Ze Ping ZHANG Mei ZHANG Jian JIANG Yong MI Sheng Quan WANG Zhuo Qun ZHAO Yan Fang SONG Peng Kun YIN Zhao Xue ZHAO Wen Hua | 2020 | Biomedical and Environmental Sciences2020，33，4： | 2 |
| 16 | Luteolin delays photoreceptor degeneration in a mouse model of retinitis pigmentosa显示文摘Luteolin is neuroprotective for retinal ganglion cells and retinal pigment epithelial cells after oxidative injury,whereby it can inhibit microglial neurotoxicity.Therefore,luteolin holds the potential to be useful for treatment of retinal diseases.The purpose of this study was to investigate whether luteolin exhibits neuroprotective effects on rod cells in rd10 mice,a slow photoreceptor-degenerative model of retinitis pigmentosa.Luteolin(100 mg/kg)intraperitoneally injected daily from postnatal day 14(P14)to P25 significantly enhanced the visual performance and retinal light responses of rd10 mice at P25.Moreover,it increased the survival of photoreceptors and improved retinal structure.Mechanistically,luteolin treatment attenuated increases in reactive oxygen species,photoreceptor apoptosis,and reactive gliosis;increased mRNA levels of anti-inflammatory cytokines while lowering that of pro-inflammatory and chemoattractant cytokines;and lowered the ratio of phospho-JNK/JNK.Application of the JNK inhibitor SP600125 exerted a similar protective effect to luteolin,suggesting that luteolin delays photoreceptor degeneration and functional deterioration in rd10 mice through regulation of retinal oxidation and inflammation by inhibiting the JNK pathway.Therefore,luteolin may be useful as a supplementary treatment for retinitis pigmentosa.This study was approved by the Qualified Ethics Committee of Jinan University,China(approval No.IACUC-20181217-02)on December 17,2018. | Xiao-Bin Liu Feng Liu Yi-Yao Liang Gang Yin Hui-Jun Zhang Xue-Song Mi Zai-Jun Zhang Kwok-Fai So Ang Li Ying Xu | 2021 | Neural Regeneration Research2021，16，10： | 2 |
| 17 | Mathematical Model of Combustion in Blunt Annular Ceramic Burner显示文摘The computer simulation of the combustion process in blast furnace (BF) stove has been studied by using the k-ε-g turbulent diffusion flame model. The combustion process in blunt annular ceramic burner was calculated by using the software. The profiles of gas and air velocity, temperature of the combustion products, concentration of the components, and the shape and length of the flame during combustion have been researched . Compared with the original annular ceramic burner, the new design of the blunt one improves the mixing of the gas and the air significantly, and shortened the length of the flame. | ZHANG Yin HE You-duo LI Shi-qi SHEN Yi-shen HUANG Xiao-yu TANG Qing-hua LI Heng-xu WANG Mi | 2001 | Journal of Iron and Steel Research(International)2001，8，2： | 2 |
| 18 | Deformation behavior of TiNiFe alloy in isothermal compression显示文摘The hot deformation behavior of TiNiFe shape memory alloy was studied by isothermal compression tests.It was performed on a Gleeble-3500 thermal simulation machine at deformation temperature of 750 to 1050 ℃ and strain rate of 0.01 to 10.00 s^(-1) with maximum strain of 0.8.Deformation mechanism was investigated by the aid of true stress-true strain curves,kinetic analysis and processing map.The constitutive relationship was established in the form of Arrhenius-type hyperbolic-sine equation,and the apparent activation energy was calculated to be approximately 200 kJ·mol^(-1).The processing maps of TiNiFe alloy were appreciably influenced by true strain. | Wang, Shujuan Mi, Xujun Yin, Xiangqian Li, Yanfeng | 2012 | Rare Metals2012，31，4： | 2 |
| 19 | Effects of preloads on joints on dynamic stiffness of a whole machine tool structure显示文摘 | LIANG Mi YIN Guofu SUN Mingnan | | 0，，2： | 1 |
| 20 | Improved shape memory composites combined with TiNi wire and shape memory epoxy显示文摘 | Xue Feng Limin Zhao Xujun Mi Yanfeng Li Haofeng Xie Xiangqian Yin Baodong Gao | 2013 | Materials and Design2013，，： | 1 |
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