|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Predictive value of ^(18)F-fluorodeoxyglucose PET/CT for transarterial chemolipiodolization of hepatocellular carcinoma显示文摘Myeong Jun Song,Si Hyun Bae,Chung-Hwa Park,Jeong Won Jang,Jong Young Choi,Seung Kew Yoon,Department of Internal Medicine,College of Medicine,The Catholic University of Korea,Seoul 137-040,South Korea Ie Ryung Yoo,Department of Nuclear,Medicine College of Medicine,The Catholic University of Korea,Seoul 137-040,South Korea Ho Jong Chun,Byung Gil Choi,Hae Giu Lee,Department of Radiology,College of Medicine,The Catholic University of Korea,Seoul 137-040,South | Myeong Jun Song Si Hyun Bae Ie Ryung Yoo Chung-Hwa Park Jeong Won Jang Ho Jong Chun Byung Gil Choi Hae Giu Lee Jong Young Choi Seung Kew Yoon | 2012 | World Journal of Gastroenterology2012，18，25： | 8 |
| 2 | Durability of viral response after off-treatment in HBeAg positive chronic hepatitis B显示文摘AIM:To evaluate the durability in hepatitis B e antigen (HBeAg) positive chronic hepatitis B patients who discontinued antiviral treatment. METHODS:A total of 48 HBeAg positive chronic hepatitis B patients who were administered nucleoside analogues and maintained virological response for ≥ 6 mo [hepatitis B virus (HBV) DNA < 300 copies/mL and HBeAg seroconversion] before cessation of treatment were enrolled between February 2007 and January 2010. The criteria for the cessation of the antiviral treatment were defined as follows:(1) achievement of virological response; and (2) duration of consolidation therapy (≥ 6 mo). After treatment cessation, the patients were followed up at 3-6 mo intervals. The primary endpoint was serologic and virologic recurrence rates after withdrawal of antiviral treatment. Serologic recurrence was defined as reappearance of HBeAg positivity after HBeAg seroconversion. Virologic recurrence was defined as an increase in HBV-DNA level > 104 copies/mL after HBeAg seroconversion with previously undetectable HBV-DNA level. RESULTS:During the median follow-up period of 18.2 mo (range:5.1-47.5 mo) after cessation of antiviral treatment, the cumulative serological recurrence rate was 15 % at 12 mo. The median duration between the cessation of antiviral treatment and serologic recurrence was 7.2 mo (range:1.2-10.9 mo). Of the 48 patients with HBeAg positive chronic hepatitis, 20 (41.6%) showed virological recurrence. The cumulative virologic recurrence rates at 12 mo after discontinuing the antiviral agent were 41%. The median duration between off-treatment and virologic recurrence was 7.6 mo (range:4.3-27.1 mo). The mean age of the virological recurrence group was older than that of the non-recurrence group (46.7 ± 12.1 years vs 38.8 ± 12.7 years, respectively; P = 0.022). Age (> 40 years) and the duration of consolidation treatment (≥ 15 mo) were significant predictive factors for offtreatment durability in the multivariate analysis [P = 0.049, relative risk (RR) 0.31, 95% CI (0.096-0.998) and P = 0.005, RR 11.29, 95% CI (2.054-65.12), respectively]. Patients with age (≤ 40 years) who received consolidation treatment (≥ 15 mo) significantly showed durability in HBeAg positive chronic hepatitis B patients (P = 0.014). These results suggest that additional treatment for more than 15 mo after HBeAg seroconversion in patients who are ≤ 40 years old may be beneficial in providing a sustained virological response. CONCLUSION:Our data suggest that HBeAg seroconversion is an imperfect end point in antiviral treatment. Long-term consolidation treatment (≥ 15 mo) in younger patients is important for producing better prognosis in HBeAg positive chronic hepatitis B. | Myeong Jun Song Do Seon Song Hee Yeon Kim Sun Hong Yoo Si Hyun Bae Jong Young Choi Seung Kew Yoon Yong-Han Paik June Sung Lee Hyun Woong Lee Hyung Joon Kim | 2012 | World Journal of Gastroenterology2012，18，43： | 7 |
| 3 | Prevalence of insulin resist- ance and metabolic syndrome in patients with gouty arthritis显示文摘 | Yoo HG Lee SI Chae HJ | 2009 | Rheumatol lnt2009，12，20： | 1 |
| 4 | Camptothecin inhibits platelet-derived growth factor-BB-induced proliferation of rat aortic vascular smooth muscle cells through inhibition of PI3K! Akt signaling pathway 显示文摘 | Park ES Kang SI Yoo KD | 2013 | Exp Cell Res2013，319，7： | 1 |
| 5 | Laparoscopic-assisted distal gastrectomy versus open distal gastrectomy for advanced gastric cancer显示文摘 | Hwang SI Kim HO Yoo CH | 2012 | Surgical Endoscopy2012，23，6： | 1 |
| 6 | Laparoscopie-assisted distal gastrectomy versus open distal gastrectomy for advanced gastric cancer显示文摘 | Hwang SI Kim HO Yoo CH | 2009 | Surg Endosc2009，23，6： | 1 |
| 7 | Laparoscopie - assisted distal gas- trectomy versus open distal gastrectomy for advanced gastric cancer显示文摘 | Hwang SI Kim HO Yoo CH | 2009 | Surg Endosc2009，23，6： | 1 |
| 8 | Significance of noncalcified coro- nary plaque in asymptomatic subjects with low coronary artery cal- cium score: assessment with coronary computed tomography angi- ography 显示文摘 | Yoo DH Chun EJ Choi SI | 2011 | Int J Cardiovasc Imaging2011，27，1： | 1 |
| 9 | Adrenal tuberculosis in Cushing'sdisease with bilateral macronodular adrenocortical hyperplasia显示文摘 | Kwon HS Kim SI Yoo SJ | 2006 | Endocr J2006，53，2： | 1 |
| 10 | Laparoscopic-assisted distal gastrectomy versus open distal gastrectomy for advanced gastreetomy for advanced gastric cancer显示文摘 | Hwang SI Kim HO Yoo CH | 2009 | Surg Endosc2009，23，6： | 1 |
| 11 | Laparoscopic-assisted distal gastrectomy versus open distal gastrectomy for advanced gastric cancer显示文摘 | Hwang SI Kim HO Yoo CH | 2009 | Surg Endosc2009，23，6： | 1 |
| 12 | Various types ofintracorporeal esophagojejunostomy after laparoscopic totalgastrectomy for gastric cancer 显示文摘 | Shim JH Yoo HM Oh SI | 2013 | Gastric Cancer2013，16，： | 1 |
| 13 | Various types of intracorporcal esophagojejunostomy after laparoscopie total gastrectomy for gastric cancer显示文摘 | Shim JH Yoo HM Oh SI ct al | 2013 | Gastric Cancer2013，16，3： | 1 |
| 14 | Feulgen reaction study of novel threadlike structures ( Bong- hart ducts) on the surfaces of mammalian organs 显示文摘 | Shin HS Johng HM Lee BC Cho SI Soh KS Baik KY Yoo JS Soh KS | 2005 | Anat Rec2005，284，： | 1 |
| 15 | Laparoscopic-assisted distal gastrectomy versus open distal gastrectomy for advanced gastric cancer显示文摘 | Hwang SI Kim HO Yoo CH | 2009 | Surg Endosc2009，23，6： | 1 |
| 16 | Prevalence of insulin resistance and metabolic syndrome in patients with gouty arthritis显示文摘 | Yoo HG Lee SI Chae HJ | 2009 | Rheumatol lnt2009，31，4： | 1 |
| 17 | Simulation and real-time monitoring of polymerase chain reactlon for its higher efficiency 显示文摘 | Lee JY Lin HW Yoo SI Yoo | 2006 | Biochemical Engineering Journal2006，29，： | 1 |
| 18 | Prevalence of insulin resistance and metabolic syndrome in patients with gouty arthritis 显示文摘 | Yoo HG Lee SI Chae HJ | 2011 | Rheu- matol Int2011，31，4： | 1 |
| 19 | Laparoscopic-assisted distal gastrectomy versus open distal gastrectomy for advanced gastric cancer 显示文摘 | Hwang SI Kim HO Yoo CH | 2009 | Surg Endosc2009，23，6： | 1 |
| 20 | Molecular characterization of duck interleukin-17显示文摘 | Yoo J Jang SI Kim S | 2009 | Vet Immunol Immunopathol2009，132，24： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员