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| 1 | Totally laparoscopic total gastrectomy using the modified overlap method and conventional open total gastrectomy:A comparative study显示文摘BACKGROUND Although several methods of totally laparoscopic total gastrectomy(TLTG)have been reported.The best anastomosis technique for LTG has not been established.AIM To investigate the effectiveness and surgical outcomes of TLTG using the modified overlap method compared with open total gastrectomy(OTG)using the circular stapled method.METHODS We performed 151 and 131 surgeries using TLTG with the modified overlap method and OTG for gastric cancer between March 2012 and December 2018.Surgical and oncological outcomes were compared between groups using propensity score matching.In addition,we analyzed the risk factors associated with postoperative complications.RESULTS Patients who underwent TLTG were discharged earlier than those who underwent OTG[TLTG(9.62±5.32)vs OTG(13.51±10.67),P<0.05].Time to first flatus and soft diet were significantly shorter in TLTG group.The pain scores at all postoperative periods and administration of opioids were significantly lower in the TLTG group than in the OTG group.No significant difference in early,late and esophagojejunostomy(EJ)-related complications or 5-year recurrence free and overall survival between groups.Multivariate analysis demonstrated that body mass index[odds ratio(OR),1.824;95%confidence interval(CI):1.029-3.234,P=0.040]and American Society of Anaesthesiologists(ASA)score(OR,3.154;95%CI:1.084-9.174,P=0.035)were independent risk factors of early complications.Additionally,age was associated with≥3 Clavien-Dindo classification and EJrelated complications.CONCLUSION Although TLTG with the modified overlap method showed similar complication rate and oncological outcome with OTG,it yields lower pain score,earlier bowel recovery,and discharge.Surgeons should perform total gastrectomy cautiously and delicately in patients with obesity,high ASA scores,and older ages. | Chang Seok Ko Nam Ryong Choi Byung Sik Kim Jeong Hwan Yook Min-Ju Kim Beom Su Kim | 2021 | World Journal of Gastroenterology2021，27，18： | 8 |
| 2 | Cytotoxicity and anti-inflammatory effects of root bark extracts of Acanthopanax henryi显示文摘AIM: To investigate the cytotoxicity, anti-inflammatory activity, and action mechanism of root bark extracts of Acanthopanax henryi. METHOD: The hot methanol extract of the root bark of A. henryi was subjected to XAD-4 column chromatography eluting with a gradient of methanol in water. The cytotoxicity and anti-inflammatory effects of the MeOH fractions were evaluated on the inhibition on lipopolysaccharide(LPS)-induced nitric oxide, prostaglandin E2, interleukin-1β, and interleukin-6 production in RAW 264.7 macrophages. RESULTS: The 80% MeOH fraction was a better inhibitor of LPS-induced NO, PGE2, IL-1β, and IL-6 production, and expression of inducible nitric oxide synthase(iNOS) at the protein levels in a concentration-dependent manner. CONCLUSION: The 80% MeOH fraction of A. henryi root bark has significant anti-inflammatory activity. This provides a pharmacological basis for clinical application for the treatment of inflammation. | KIM Jong-Hwan LIU Xiang-Qian DAI Ling YOOK Chang-Soo LEE Kyung-Tae | 2014 | Chinese Journal of Natural Medicines2014，12，2： | 5 |
| 3 | Metallic stent placement in the palliative treatment of malignant gastroduodenal obstructions: prospective evaluation of results and factors influencing outcome in 213 patients显示文摘 | Jin Hyoung Kim Ho-Young Song Ji Hoon Shin Eugene Choi Tae Won Kim Hwoon-Yong Jung Gin Hyug Lee Sung Koo Lee Myung-Hwan Kim Min-Hee Ryu Yoon-Koo Kang Byung Sik Kim Jeong Hwan Yook | 2007 | Gastrointestinal Endoscopy2007，，2： | 2 |
| 4 | Optimal proximal resection margin distance for gastrectomy in advanced gastric cancer显示文摘BACKGROUND The conventional guidelines to obtain a safe proximal resection margin(PRM)of5-6 cm during advanced gastric cancer(AGC)surgery are still applied by many surgeons across the world.Several recent studies have raised questions regarding the need for such extensive resection,but without reaching consensus.This study was designed to prove that the PRM distance does not affect the prognosis of patients who undergo gastrectomy for AGC.AIM To investigate the influence of the PRM distance on the prognosis of patients who underwent gastrectomy for AGC.METHODS Electronic medical records of 1518 patients who underwent curative gastrectomy for AGC between June 2004 and December 2007 at Asan Medical Center,a tertiary care center in Korea,were reviewed retrospectively for the study.The demographics and clinicopathologic outcomes were compared between patients who underwent surgery with different PRM distances using one-way ANOVA and Fisher’s exact test for continuous and categorical variables,respectively.The influence of PRM on recurrence-free survival and overall survival were analyzed using Kaplan-Meier survival analysis and Cox proportional hazard analysis.RESULTS The median PRM distance was 4.8 cm and 3.5 cm in the distal gastrectomy(DG)and total gastrectomy(TG)groups,respectively.Patient cohorts in the DG and TG groups were subdivided into different groups according to the PRM distance;≤1.0 cm,1.1-3.0 cm,3.1-5.0 cm and>5.0 cm.The DG and TG groups showed nostatistical difference in recurrence rate(23.5%vs 30.6%vs 24.0%vs 24.7%,P=0.765)or local recurrence rate(5.9%vs 6.5%vs 8.4%vs 6.2%,P=0.727)according to the distance of PRM.In both groups,Kalpan-Meier analysis showed no statistical difference in recurrence-free survival(P=0.467 in DG group;P=0.155 in TG group)or overall survival(P=0.503 in DG group;P=0.155 in TG group)according to the PRM distance.Multivariate analysis using Cox proportional hazard model revealed that in both groups,there was no significant difference in recurrence-free survival according to the PRM distance.CONCLUSION The distance of PRM is not a prognostic factor for patients who undergo curative gastrectomy for AGC. | Amy Kim Beom Su Kim Jeong Hwan Yook Byung Sik Kim | 2020 | World Journal of Gastroenterology2020，26，18： | 2 |
| 5 | EMR versus gastrectomy for intramucosal gastric cancer: comparison of long-term outcomes显示文摘 | Kwi-Sook Choi Hwoon-Yong Jung Kee Don Choi Gin Hyug Lee Ho June Song Do Hoon Kim Jeong Hoon Lee Mi-Young Kim Byung Sik Kim Sung Tae Oh Jeong Hwan Yook Se Jin Jang Sung-Cheol Yun Seon Ok Kim Jin-Ho Kim | 2011 | Gastrointestinal Endoscopy2011，，5： | 2 |
| 6 | Laparoscopic Gastrectomy in Patients With Previous Gastrectomy for Gastric Cancer: A Report of 17 Cases显示文摘 | Hee Sung Kim Beom Su Kim In Seob Lee Sol Lee Jeoung Hwan Yook Byung Sik Kim | 2014 | Surgical Laparoscopy, Endoscopy & Percutaneous Techniques2014，，2： | 2 |
| 7 | Signet ring cell type and other histologic types: differing clinical course and prognosis in T1 gastric cancer显示文摘 | Beom Su. Kim Seong Tae Oh Jeong Hwan Yook Byug Sik Kim | 2013 | Surgery2013，，： | 2 |
| 8 | Mirtazapine augmentation enhances cognitive and reduces negative symptoms in schizophrenia patients treated with risperidone:A randomized controlled trial显示文摘 | Cho S J Yook K Kim B | 2011 | Prog Neu- ropsychopharmacol Biol Psyehiatry2011，35，1： | 1 |
| 9 | Comparison of early outcomes of intracorporeal and extracorporeal gastroduodenostomy after laparoscopic distal gastrectomy for gastric cancer显示文摘 | KIM B S YOOK J H CHOI Y B | 2011 | J Laparoendosc Adv Surg Tech A2011，21，5： | 1 |
| 10 | Influence of obesity on early surgical outcomes of laparoscopic-assisted gastrectomy in gastric cancer显示文摘 | Kim MG Yook JH Kim KC | 2011 | Surg Laparosc Endosc Percutan Tech2011，21，3： | 1 |
| 11 | Comparison of early outcomes of intracorporeal and extracorporeal gastroduodenostomy after laparoscopic distal gastrectomy for gastric cancer 显示文摘 | Kim BS Yook JH Choi YB | 2011 | J Laparo- endosc Adv Surg Tech A2011，21，5： | 1 |
| 12 | Nutritional, physiological, physicochemical and sensory stability of gamma irradiated Kimchi (Korean fermented vegetables ) 显示文摘 | Song H P Kim D H Yook H S | 2004 | Radiation Physics and Chemistry2004，69，： | 1 |
| 13 | Comparison of early outcomes of intracorporeal and extracorporeal gastroduodenostomy after laparoscopic distal gastrectomy for gastric cancer 显示文摘 | Kim BS Yook JH Choi YB | 2011 | J Lapar- oendosc Adv Surg Tech A2011，21，5： | 1 |
| 14 | Changes in microbiological and general qualities in gamma irradiated Doenjang (fermented soybean paste) 显示文摘 | Byun M W Kim D H Yook H S | 2001 | Food Science and Biotechnology2001，10，： | 1 |
| 15 | Porous titanium(Ti) scaffolds by freezing TiH2/camphene slurries显示文摘 | YOOK SW YOON BH KIM HE KON YH KIM YS | 2008 | Materials Letters2008，62，30： | 1 |
| 16 | Immunohistochemical study on proliferating cell nuclear antigen expression in ameloblastomas显示文摘 | Kim J Yook J I | 1994 | Eur J Cancer B Oral Oncel1994，30，2： | 1 |
| 17 | Enhancement of preservation characteristics of Meju, and intermediate material for Korean legumebased fermented soy sauce, Kanjang, by irradiation 显示文摘 | Kim D H Jo C Yook H S | 2002 | Radiation Physics and Chemistry2002，64，： | 1 |
| 18 | A Lupane-Triterpene Glycoside from Leaves of Two Acanthopanax显示文摘 | Yook C S Kim H Hahn DR | 1998 | Phytochemistry1998，49，3： | 1 |
| 19 | Effects of gamma radiation on the allergenic and antigenic properties of milk proteins显示文摘 | Lee J W Kim J H Yook H S | 2001 | J Food Prot2001，64，： | 1 |
| 20 | Color, flavor, and sensory characteristics of gamma-irradiated salted and fermented anchovy sauce显示文摘 | Kim J H Ahn H J Yook H S | 2004 | Radiation Physics and Chemistry2004，691，： | 1 |
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