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| 1 | 体内腺相关病毒-常间回文重复序列丛集及其相关蛋白9介导的基因编辑可改善家族性高胆固醇血症的动脉粥样硬化显示文摘低密度脂蛋白受体(low-density lipoprotein receptor,Ldlr)基因突变是家族性高胆固醇血症的主要原因之一,可导致动脉粥样硬化,并具有很高的终生心血管病风险。常间回文重复序列丛集(clustered regularly interspaced short palindromic repeats,CRISPR)/CRISPR相关蛋白9(CRISPR-related protein 9,Cas9)系统是基因编辑纠正基因突变从而改善疾病的有效工具。该研究的目的是通过腺相关病毒(adeno-associated virus,AAV)携带的CRISPR/Cas9系统进行体内体细胞基因编辑,以确定其能否在小鼠模型中治疗由Ldlr突变体引起的家族性高胆固醇血症。 | 刘青(译) 叶鹏(审校) Zhao H Li Y He L Pu W Yu W Li Y Wu YT Xu C Wei Y Ding Q Song BL Huang H Zhou B | 2020 | 中华高血压杂志2020，28，3： | 22 |
| 2 | Properties of lead-free solder alloys with rare earth element additions显示文摘 | WU C M L YU D Q LAW C M T WANG L | 2004 | Materials Science and Engineering2004，44，1： | 2 |
| 3 | The existence of Intera-Granular ferrite plates and nucleating inclusions in the heat affected zone of X60 pipe steel显示文摘 | Guo C J Yu R Z Zhu Q G | 1997 | J Mater Sci1997，，： | 1 |
| 4 | Evaluation of Newcastle disease virus chimeras expressing the Hemagglutinin-Neuraminidase protein of velogenic strains in the context of a mesogenic recombinant virus backbone显示文摘 | Estevez C King D Seal B Yu Q | 2007 | Virus Res2007，129，2： | 1 |
| 5 | A novel tool to assess systolic asynchrony and identify responders of cardiac resynchronization therapy by tissue synchronization imaging 显示文摘 | YU C M ZHANG Q FUNG J W | 2005 | J Am Coll Cardiol2005，45，5： | 1 |
| 6 | The properties of Sn-9Zn lead-free solder alloys doped with trace rare earth elements 显示文摘 | Wu C M L Yu D Q Law C M T | 2002 | Journal of electronic materials2002，31，9： | 1 |
| 7 | Synthesis and character- ization of low crystalline waterborne polyurethane for potential application in water - based ink binder显示文摘 | Fang C Q Zhou X Yu Q | 2014 | Progress in Organic Coatings2014，77，1： | 1 |
| 8 | Expression pattern genomic struc- ture, and promoter analysis of the gene encoding stilbene synthase from Chinese wild Vitis pseudoreticulata显示文摘 | XU W R YU Y H ZHOU Q DING J H DAI L M XIE X Q XU Y ZHANG C H WANG Y J | 2011 | Journal of Experimen- tal Botany2011，62，8： | 1 |
| 9 | The TIL commissioning and performance显示文摘 | X Zhang W Zheng X Wei F Jing Z Sui K Zheng Q Xu X Yuan X Jiang L Yang P Ma M Li J Wang D Hu S He F Li Z Peng B Feng H Zhou L Guo X Li X Zhang J Su Q Zhu H Yu R Zhao C Ma H He D Fan W Zhang | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 10 | The Isolation and Characterization of Lignin of Kenaf Fiber显示文摘 | Yah T T Xu Y Q Yu C W | 2009 | J Appl Polym Sci2009，114，3： | 1 |
| 11 | A novel density-tunable nanoeomposites of CdTe quantum dots linked to dendrimer-tethered multiwall carbon nanotubes显示文摘 | Zeng Y L Tang C R Wang H W Jiang J H Tian M N Shen G L Yu R Q | 2008 | Spectrochimica Acta Part A:Molecular and Biomolecular Spectroscopy2008，70，5： | 1 |
| 12 | In vitro and in vivo neuroprotective effect and mechanisms of glabridin, a major active isoflavan from Glycyr- rhiza glabra (licorice) 显示文摘 | Yu X Q Xue C C Zhou Z W | 2008 | Life Sci2008，82，： | 1 |
| 13 | Preparation of Machinable Bioactive Glass-ceramics显示文摘 | NING Q J SHI Y S WANG X F YU C L SUN X M | 2005 | Journal of Wuhan university of technology2005，20，1： | 1 |
| 14 | Properties of lead-free solder alloys with rare earth element additions 显示文摘 | Wu C M L Yu D Q Law C M T | 2004 | Materials Science and Engineering2004，44，： | 1 |
| 15 | Survival analysis of laryngeal carcinoma without laryngectomy,radio therapy,or chemotherapy显示文摘 | Yu Q Zhang X Ji C | 2012 | European Archives of Oto-Rhino Laryngology2012，269，9： | 1 |
| 16 | 查看详情显示文摘 | Pei Q Yu G Zhang C | | 0，，： | 1 |
| 17 | Reproducible tip fabrication and cleaningfor UHV STM 显示文摘 | Yu Z Q Wang C M Du Y Thevuthasan S Lyubinetsky I | 2008 | Ultramicroscopy2008，108，9： | 1 |
| 18 | Cyclic Testing of Steel Moment Connections Rehabilitated with RBS or Welded Haunch显示文摘 | Uang C M Yu Q S Gross J | 2000 | Struct Engrg ASCE2000，126，1： | 1 |
| 19 | Spatial distribution, potential risk as- sessment, and source apportionment of polycyclic aromatic hydrocarbons (PAHs) in sediments of Lake Chaohu, China显示文摘 | LI C C HUO S L YU Z Q | 2014 | Environmental science and pollution research2014，21，12： | 1 |
| 20 | Effect of Liquid Culture Requirements on Antifungal Antibiotic Production by Streptomyces Rimosus MY02显示文摘 | YU J C LIU Q LIU Q | 2008 | Bioresour Technol2008，99，6： | 1 |
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