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| 1 | 体内腺相关病毒-常间回文重复序列丛集及其相关蛋白9介导的基因编辑可改善家族性高胆固醇血症的动脉粥样硬化显示文摘低密度脂蛋白受体(low-density lipoprotein receptor,Ldlr)基因突变是家族性高胆固醇血症的主要原因之一,可导致动脉粥样硬化,并具有很高的终生心血管病风险。常间回文重复序列丛集(clustered regularly interspaced short palindromic repeats,CRISPR)/CRISPR相关蛋白9(CRISPR-related protein 9,Cas9)系统是基因编辑纠正基因突变从而改善疾病的有效工具。该研究的目的是通过腺相关病毒(adeno-associated virus,AAV)携带的CRISPR/Cas9系统进行体内体细胞基因编辑,以确定其能否在小鼠模型中治疗由Ldlr突变体引起的家族性高胆固醇血症。 | 刘青(译) 叶鹏(审校) Zhao H Li Y He L Pu W Yu W Li Y Wu YT Xu C Wei Y Ding Q Song BL Huang H Zhou B | 2020 | 中华高血压杂志2020，28，3： | 22 |
| 2 | Properties of lead-free solder alloys with rare earth element additions显示文摘 | WU C M L YU D Q LAW C M T WANG L | 2004 | Materials Science and Engineering2004，44，1： | 2 |
| 3 | Enhanced high-potential and elevated-temperature cycling stability of LiMn2O4 cathode by TiO2 modification for Li-ion battery 显示文摘 | Yu L Qiu x xi J Zhu W T Chen L Q | 2006 | Eleetrochimica Acta2006，51，： | 1 |
| 4 | A novel titanium-supported Ag/Ti electrode for the electro-oxidation of hydrazine 显示文摘 | Yi Q F Li L Yu W Q | 2008 | Journal of Molecular Catalysis A: Chemical2008，295，： | 1 |
| 5 | Rare-earth oxide coating for sub-micro particulates reinforced aluminum matrix composites 显示文摘 | YU Z Q WU G H SUN D L | 2003 | Mater Sci Eng2003，357，： | 1 |
| 6 | Hypoxia-inducible factor-1 alpha is essentialfor hypoxia-induced mesenchymal stem cell mobilization into theperipheral blood显示文摘 | Liu L Yu Q Lin J | 2011 | Stem Cells Dev2011，20，11： | 1 |
| 7 | Comparison of intensive and low-dose atorvastatin therapy in the reduction of ca- rotid intimal-medial thickness in patients with coronary heart disease 显示文摘 | Yu CM Zhang Q Lam L | 2007 | Heart2007，93，8： | 1 |
| 8 | A real explosion: The requirement of steam explosion pretreatment显示文摘 | Yu Z D Zhang B L Yu F Q | 2012 | Bioresource Technology2012，121，： | 1 |
| 9 | Liquid hot water pretreatment of sugarcane bagasse and its comparison with chemical pretreatment methods for the sugar recovery and structural changes显示文摘 | Yu Q Zhuang X S Lv S L | | 0，，02： | 1 |
| 10 | The properties of Sn-9Zn lead-free solder alloys doped with trace rare earth elements 显示文摘 | Wu C M L Yu D Q Law C M T | 2002 | Journal of electronic materials2002，31，9： | 1 |
| 11 | Investigation on the under cooling and crystallization of pure aluminum melt by DSC显示文摘 | Yu J Qiao Q Liu L | 2010 | Phase Transitions2010，83，7： | 1 |
| 12 | Freeze-drying of human red blood cells: influence of carbohydrates and their concentrations显示文摘 | Yu Jianping Liu J H Pu L Q Cui Xiangdong Wang Changzheng Ouyang S L Gao Dayong | 2004 | Cell Preservation Technology2004，2，4： | 1 |
| 13 | Biosynthesis of aminoglycoside antibiotics: cloning, expression and characterization of an aminotransferase involved in the pathway to 2-deoxystreptamine显示文摘 | Huang F L Li Y Y Yu J Q | 2002 | Chem Commun2002，23，： | 1 |
| 14 | Expression pattern genomic struc- ture, and promoter analysis of the gene encoding stilbene synthase from Chinese wild Vitis pseudoreticulata显示文摘 | XU W R YU Y H ZHOU Q DING J H DAI L M XIE X Q XU Y ZHANG C H WANG Y J | 2011 | Journal of Experimen- tal Botany2011，62，8： | 1 |
| 15 | The TIL commissioning and performance显示文摘 | X Zhang W Zheng X Wei F Jing Z Sui K Zheng Q Xu X Yuan X Jiang L Yang P Ma M Li J Wang D Hu S He F Li Z Peng B Feng H Zhou L Guo X Li X Zhang J Su Q Zhu H Yu R Zhao C Ma H He D Fan W Zhang | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 16 | Calculation of Magnetic Properties and Analysis of Valence Electronic Structures of Compounds 显示文摘 | Guo Y Q Yu R H Zhang R L | 1998 | Journal of Physical Chemistry1998，102，： | 1 |
| 17 | Study on nano-CaCO3 modified epoxy powder coatings显示文摘 | Yu H J Wang L Shi Q | 2006 | Progress in Organic Coatings2006，55，3： | 1 |
| 18 | A novel density-tunable nanoeomposites of CdTe quantum dots linked to dendrimer-tethered multiwall carbon nanotubes显示文摘 | Zeng Y L Tang C R Wang H W Jiang J H Tian M N Shen G L Yu R Q | 2008 | Spectrochimica Acta Part A:Molecular and Biomolecular Spectroscopy2008，70，5： | 1 |
| 19 | Montelukast, a cysteinyl leukotriene receptor-1 antago-nist, dose- and time-dependently protects against focal cerebral ischemia in mice 显示文摘 | YU G L WEI E Q ZHANG S H | 2005 | Pharmacology2005，73，1： | 1 |
| 20 | Preparation of Machinable Bioactive Glass-ceramics显示文摘 | NING Q J SHI Y S WANG X F YU C L SUN X M | 2005 | Journal of Wuhan university of technology2005，20，1： | 1 |
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