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| 1 | Platelet count/spleen diameter ratio to predict esophageal varices in Mexican patients with hepatic cirrhosis显示文摘AIM:To validate whether the platelet count/spleen size ratio can be used to predict the presence of esophageal varices in Mexican patients with hepatic cirrhosis.METHODS:This was an analytical cross-sectional study to validate the diagnostic test for hepatic cirrhosis and was performed between February 2010 and December 2011.Patients with a diagnosis of hepatic cirrhosis were included and stratified using their ChildPugh score.Biochemical parameters were evaluated,and ultrasound was used to measure the longest diameter of the spleen.The platelet count/spleen diameter ratio was calculated and analyzed to determine whether it can predict the presence of esophageal varices.Upper gastrointestinal endoscopy was used as the gold standard.Sensitivity and specificity,positive and negative predictive values,and positive and negative likelihood ratios were determined,with the cutoff points determined by receiver-operating characteristic curves.RESULTS:A total of 91 patients were included.The mean age was 53.75±12 years;50(54.9%)were men,and 41(45.0%)women.The etiology of cirrhosis included alcohol in 48(52.7%),virally induced in24(26.3%),alcoholism plus hepatitis C virus in three(3.2%),cryptogenic in nine(9.8%),and primary biliary cirrhosis in seven(7.6%).Esophageal varices were present in 73(80.2%)patients.Child-Pugh classification,17(18.6%)patients were classified as class A,37(40.6%)as class B,and 37(40.6%)as class C.The platelet count/spleen diameter ratio to detect esophageal varices independent of the grade showed using a cutoff value of≤884.3,had 84%sensitivity,70%specificity,and positive and negative predictive values of 94%and 40%,respectively.CONCLUSION:Our results suggest that the platelet count/spleen diameter ratio may be a useful tool for detecting esophageal varices in patients with hepatic cirrhosis. | Alejandro González-Ojeda Gabino Cervantes-Guevara Manuela Chávez-Sánchez Carlos Dávalos-Cobián Susana Ornelas-Cázares Michel Dassaejv Macías-Amezcua Mariana Chávez-Tostado Kenia Militzi Ramírez-Campos Anaís del Rocío Ramírez-Arce Clotilde Fuentes-Orozco | 2014 | World Journal of Gastroenterology2014，20，8： | 18 |
| 2 | 表面印迹聚合物及其在微流控器件中的应用显示文摘分子印迹聚合物是通过在模板存在下固化交联的聚合物制备的.在固化过程中,聚合物和模板间形成非共价键.这些非共价结合位点被'冻结'在交联的聚合物中,即使移去模板后也依然维持他们的形状.余下的空穴与模板的尺寸和形状一致,并且可以选择性地从流过的混合物中俘获模板物质.在近几十年中,分子印迹的领域由选择性俘获小分子扩展到处理各种类型的样品.分子印迹聚合物(MIP)被用于分析种类繁多的样品,比如金属离子、药物分子、环境污染物、蛋白、病毒以至整个细胞.本文中我们综述相对较新的领域——表面印迹,这是一种可以用来生成相对较大的生物相关模板的印迹方法.传统的整体印迹法是直接在固化前将模板加入预聚体中,因而不适用于那些大到无法从固化后的聚合物中扩散出来的物质.要仅在表面上生成结合位点,必须要使用特别的方法,由此产生的表面印迹技术解决了分离科学以及化学和生物化学监测的重要问题.将印迹聚合物植入微流控芯片,大大扩展了微流体技术的适用性.本文叙述表面印迹最新的进展以及不同的实施手段,以及它们在微流控器件中的应用. | SCHIRHAGL Romana 任康宁 ZARE Richard N | 2012 | 中国科学:化学2012，42，7： | 2 |
| 3 | Tunable Laser Fluorescence Method for Product State Analysis显示文摘 | R N Zare P J Dagdigian | | 0，，185： | 1 |
| 4 | People with impaired glucose tol- erance and impafed fasting glucose are similarlysusceptible to cardi- ovascular disease:a study in first-degree relatives of type 2 diabetic patients显示文摘 | Amini M Horri N Zare M | 2010 | Ann Nutr Metab2010，56，4： | 1 |
| 5 | Surface plasmon resonance imaging using a high numerical aperture microscope objective 显示文摘 | HUANG B YU F ZARE R N | 2007 | Analytical Chemistry2007，79，7： | 1 |
| 6 | A comparison of the ratio of patient's height to thyromental distance with the modified Mallampati and the upper lip bite test in predicting difficult laryngoscopy显示文摘 | Safavi M Honarmand A Zare N | 2011 | Saudi J Anaesth2011，5，3： | 1 |
| 7 | Protocol for resolving protein mixtures in CZE显示文摘 | Gordon M J Lee K J Zare R N | 1991 | Anal Chem1991，63，： | 1 |
| 8 | De termination of carbohydrates by capillary zone dec trophoresis with amperometric detection at a cop per microelectrode显示文摘 | Luis A Colon Rajeev Dadoo Richard N Zare | 1993 | Anal Chem1993，65，： | 1 |
| 9 | PSP visualization studies on a convergent nozzle with an ejector system 显示文摘 | ZARE - BEHTASH H GONGORA - OROZCO N KONTIS K | 2009 | Journal of Visualization2009，12，2： | 1 |
| 10 | Electrochemical properties of a tetrabromo-p-benzoquinone modified carbon paste electrode application to the simultaneous determination of ascorbic acid dopamine and uric acid显示文摘 | Zare H R Nasirizadeh N Mazloum Ardakani M | 2005 | J Electroanal Chem2005，577，1： | 1 |
| 11 | Evidence that polycyclic aromatic hydrocarbons in two carbonaceous chondrites predate parent-body formation显示文摘 | PLOWS F L ELSILA J E ZARE R N | 2003 | Geochimica et Cosmochimica Acta2003，67，7： | 1 |
| 12 | Science显示文摘 | Nie S Chiu D T Zare R N | 1994 | 266:10181994，266，： | 1 |
| 13 | People with impaired glucose tolerance and impaired fasting glucose are simi- larly susceptible to cardiovascular disease:a study in first- degree relative of type 2 diabetic patients显示文摘 | Amini M Horri N Zare M | 2010 | Ann Nutr Metab2010，56，4： | 1 |
| 14 | Platelet count response to Helicobacter pylori eradication in Iranian patients with idiopathic thrombocytopenic purpura显示文摘 | Payandeh M Sohrabi N Zare ME | 2012 | Mediterr J Hematol Infect Dis2012，4，20： | 1 |
| 15 | Electrokinetic separation of chiral compounds 显示文摘 | Gassmann E Kuo J E Zare R N | 1985 | Science1985，230，4727： | 1 |
| 16 | Cylindrospermopsin toxin production by cyanobacterialisolates from Kor River and evaluation of their effect using bioassay technique显示文摘 | Zare M&Bahador N | 2015 | Environmental and Experimental Biology2015，，11： | 1 |
| 17 | 查看详情显示文摘 | Zare R N | | 0，，： | 1 |
| 18 | The assessment of rock slope insta- bility along the Khosh -Yeylagh Main Road (Iran) using a systems approach 显示文摘 | Khalo K R Zare N M | 2012 | Environmental Earth Sciences2012，67，3： | 1 |
| 19 | Protein-inorganic hybrid nanoflowers 显示文摘 | GE J LEI J ZARE R N | 2012 | Nature Nanotechnology2012，7，7： | 1 |
| 20 | Radiative lifetime of the alkaline earth monohalides 显示文摘 | P J Dagdigian H W Cruse R N Zare | 1974 | J Chem Phys1974，60，6： | 1 |
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