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| 1 | Quantification of epicardial fat:Which method can predict significant coronary artery disease?显示文摘AIM:To compare the predictive value of three methods of epicardial fat(EF) assessment for presence of significant coronary artery disease(CAD) [i.e.,epicardial fat volume(EFV),EFV indexed with body surface area(EFV/BSA) and EFV indexed with body mass index(EFV/BMI)].METHODS:The study was performed on 170 patients(85 women and 85 men) with clinical suspicion of CAD.They aged 26-89 years with a median age of 54 years.The patients were classified into three groups:Group 1:58 patients with normal coronary arteries; group 2:48 patients with non-significant CAD and group 3:64 patients with significant CAD.The three methods for assessment of epicardial fat were retrospectively studied to determine the best method to predict the presence of significant CAD.RESULTS:The three methods for epicardial fat quantification and measurements,i.e.,EFV,EFV/BSA and EFV/BMI with post- hoc analysis showed a significant difference between patients with significant coronary artery disease compared to the normal group.Receiver operating characteristic curve analysis showed no significant difference between the three methods of epicardial fat measurements,the area under curve ranging between 0.6 and 0.62.The optimal cut-off was 80.3 cm3 for EFV,2.4 cm3/m2 for EFV indexed with BMI and 41.7 cm3/(kg/m2) for EFV indexed with BSA.For this cut-off the sensitivity ranged between 0.92 and 0.94,while specificity varied from 0.31 to 0.35.CONCLUSION:Any one of the three methods for assessment of epicardial fat can be used to predict significant CAD since all have the same equivalent predictive value. | Zizi Saad Mohamed El-Rawy Ragab H Donkol Sami Boghattas | 2015 | World Journal of Cardiology2015，7，5： | 2 |
| 2 | Site impact on colorectal cancer biological behavior in terms of clinicopathol- ogical and molecular features 显示文摘 | Papagiorgis PC Zizi AE Tseleni S | 2011 | J BUON2011，16，1： | 1 |
| 3 | Human cells and tissues: the need for a global ethical framework 显示文摘 | Pimay JP Vanderkelen A Zizi M | 2010 | Bull World Health Organ2010，88，11： | 1 |
| 4 | The pattern of epidermal growth factor receptor variation with disease progression and aggressiveness in colorectal cancer depends on tumor location 显示文摘 | Papagiorgis PC Zizi AE Tseleni S | 2012 | Oncol Lett2012，3，5： | 1 |
| 5 | Prognos- tic significance of transforming growth factor beta ( TGF - 13) sig- naling axis molecules and E - cadherin in coloreetal cancer 显示文摘 | Lampropoulos P Zizi - Sermpetzoglou A Rizos S | 2012 | Tumour Biol2012，33，4： | 1 |
| 6 | FAK, CD44v6, c- Met and EGFR in colorectal cancer- parame- ters: tumour progression, metastasis, patient survival and receptor crosstalk 显示文摘 | GAROUNIATIS A ZIZI SERMPETZOGLOU A RIZOS S | 2013 | Int J Colorectal Dis2013，28，1： | 1 |
| 7 | Obstructive sleep apnea and cardiovascular disease: role of the metabolic syndrome and its eomponents显示文摘 | Jean-Louls G Zizi F Clark LT | 2008 | J Clin Sleep Meal2008，4，3： | 1 |
| 8 | Anxiety and cardiovascular risk: review of epide miological and clinical evidence 显示文摘 | Olafiranye O Jean-Louis G Zizi F | 2011 | Mind Brain2011，2，1： | 1 |
| 9 | Resistant hypertension and ohstructive sleep apnea in the primary-care setting 显示文摘 | Demede M Pandey A Zizi F | 2011 | Int J Hypertens2011，2011，34： | 1 |
| 10 | The pattern of epidermal growth factor receptor variation with disease progression and aggressiveness in colorectal cancer depends on tumor location 显示文摘 | Papagiorgis PC Zizi AE Tseleni S | 2012 | Oneol Lett2012，3，： | 1 |
| 11 | Vascular endothelial growth factor receptors 1, 3 and caveolin - l are implicaled in colorcctal cancer aggressiveness and prognosis - correlations with epidermal growth factor receptor, CIM4v6, focal adhesion kinase, and c - Met 显示文摘 | GAROUNIATIS A ZIZI SERMPETZOGLOU A RIZOS S | 2013 | Tumour Biol2013，34，4： | 1 |
| 12 | Additive effects of combined angiotensin-converting enzyme inhibition and angiotesin II antagonist on blood pressure and rennin release in sodium-depleted normentives显示文摘 | Zizi M Chatellier G Guyene TT | 1995 | Circulation1995，92，： | 1 |
| 13 | The virtual sphere:the internet as a public sphere显示文摘 | Zizi Papacharissi | 2002 | New Media Society2002，，1： | 1 |
| 14 | Myocardial bridging analysis by coronary computed tomographic angiography in a Saudi population显示文摘AIM: To assess the incidence, location, morphology and clinical association of myocardial bridging in a Saudi population using coronary computed tomographic angiography(CCTA). METHODS: A total of 350 CCTA of Saudi patients were included in this study(236 men, 114 women) with a mean age of 56.3 years. All patients were examined for appropriateness criteria of CCTA indications(typical chest pain, recent onset cardiomyopathy, left bundle branch block, etc.). The scans were retrospectively reviewed for the presence of myocardial bridging and any other pathological association. RESULTS: Myocardial bridging was found in 89 of 350(22.5%) patients. Most of the intramuscular segments were of the superficial type and found in the mid left anterior descending(LAD)(24.6%), followed by distal LAD(3.7%), diagonal branches(2%), ramus intermedius artery(1.4%) and obtuse marginal artery(0.8%). No myocardial bridging was detected in the right coronary or circumflex arteries. No significant differences were found between males and females(P = 0.14). Coronary artery atherosclerosis was found in 51 of 89(57.3%) patients with MB. Atherosclerotic plaques were not detected in the intramuscular or distal segment of bridging arteries. Dynamic compression was observed in 35(94.5%) patients with full encasement. No evidence of myocardial hypoperfusion was found in the territories supplied by the bridging arteries. CONCLUSION: CCTA is excellent in analyzing myocardial bridging in a Saudi population and the results are comparable to other populations. However, finding the real incidence may need a large multicenter study. | Ragab Hani Donkol Zizi Saad | 2013 | World Journal of Cardiology2013，5，11： | 1 |
| 15 | Natural history,management and pharmacokinetics of everolimus-induced-oral ulcers insights into compliance issues显示文摘 | FertéC Paci A Zizi M | 2011 | Eur J Cancer2011，47，15： | 1 |
| 16 | Quality-controlled small-scale production of a well-defined bacteriophage cocktail for use in human ctinical trials 显示文摘 | Merabishvili M Pirnay JP Verbeken G Chanishvili N Tediashvili M Lashkhi N Glonti T Krylov V Mast J Van Parys L Lavigne R Volckaert G Mattheus W Vcrween G De Corte P Rose T Jennes S Zizi M De Vos D Vaneechoutte M | 2009 | PLoS One2009，4，3： | 1 |
| 17 | Sleep duration and the risk of diabetes mellitus : epidemiologlc evidence and pathophysio- logic insights显示文摘 | Zizi F Jean-Louis G Brown CD | 2010 | Curt Diab Rep2010，10，1： | 1 |
| 18 | Influence of thyroid status on serum immunoreactive leptin levels显示文摘 | Valcavi R Zizi M Peino R | 1997 | J Clin Endocrinol Metab1997，82，5： | 1 |
| 19 | FAK, CD44v6,c-Met and EGFR in colorectal cancer parameters: turnout progression, metastasis, patient survival and receptor crosstalk显示文摘 | Garouniatis A Zizi Sermpetzoqlou A Rizos S | 2013 | Int J Coloreetal Dis2013，28，1： | 1 |
| 20 | Management of Hy- pertension among Patients with Coronary Heart Disease 显示文摘 | Olafiranye O Zizi F Brimah P | 2011 | Int J Hypertens2011，2011，： | 1 |
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