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1IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treat- ment of Cancer Brain Tumor Group显示文摘van den Bent M J Dubbink HJ Marie Y Brandes AA Taphoorn MJ Wesseling P Frenay M Tijssen CC Lacombe D ldbaih A van Marion R Kros JM Dinjens WN Gorlia T. Sanson M. 2010中国神经肿瘤杂志2010,8,1:22
2Immune response to an indigenously developed r-Hepatitis B vaccine in mixed population: Study of an accelerated vaccination schedule显示文摘AIM: To establish the safety and efficacy of an indigenously developed r-hepatitis B vaccine using an accelerated schedule and to highlight the social awareness and commitment in preventing the spreading of hepatitis B virus infection.METHODS: The study was a multicentric, double blind,randomized (3:1) study using three doses of vaccine immunization schedule (20 μg for those above 10 years old and 10 μg for those below 10 years old) on d 0, 30and 60. One hundred and sixty-six subjects were enrolled(87 males and 76 females aged 5-35 years). The main outcome measure was assessment of immunogenicity and safety.RESULTS: A 100% seroconversion response was observed on the 30th d after the 1st injection in both the experimental groups. The sero-protection data reported a 41.2-65.6% response on the 30th d after the 1st injection and reached 100% on the 60th d. Descriptive statical analysis showed a geometric mean titer value of 13.77 mIU/mL in the test (BEVAC) group and 10.95 mIU/mL in the commercial control (ENGERIX-B) group on the 30th d after the 1st injection. The response on the 60th d showed a geometric mean titre value (GMT) of 519.84 mIU/mL in the BEVAC group and 475.46 mIU/mL in the ENGERIX-B group. On the 90th d, the antibody titer response was observed to be 2627.58 mIU/mL in the BEVAC group and 2272.72 mIU/mL in the ENGERIX-B group. Two subjects in each group experienced pains at injection site after the first vaccination. A total of six subjects in both groups experienced a solicited adverse reaction, which included pains, swelling and redness at the injection site, three subjects in the group-B had a pain at the injection site after the third dose. No other serious adverse events occurred and no dose-related local or general symptoms were observed during the study.CONCLUSION: The vaccine is safe, efficacious and immunogenic in comparison with the well documented ENGERIX-B.A Chowdhury A Santra CM Habibullah AA Khan J Karunakaramaiah TSA Kishore AVR Raju S Lahiri 2005World Journal of Gastroenterology2005,11,7:12
3国际胃袖状切除专家共识:基于>12000手术病例的最佳操作指南显示文摘腹腔镜胃袖状切除术(1aparoscopic sleeve gastrectomy,LSG)系相对较新的减重手术方式。因其操作相对简单、治疗肥胖合并疾病及减重效果明显,逐步得以广泛接受。目前美国代谢与减重手术协会将其推荐为肥胖症治疗的单独标准术式。2011年3月25~26日,苏远涛 徐安安 朱江帆 Diaz AA Arvidsson D Baker RS Basso N Bellanger D Boza C El Mourad H France M Gagner M Galvao-Neto M Higa KD Himpens J Hutchinson CM Jacobs M Jorgensen JO Jossart G Lakdawala M Nguyen NT Nocca D Prager G Pomp A Ramos AC Rosenthal RJ Shah S Vix M Wittgrove A Zundel N 2013中国微创外科杂志2013,13,9:12
4Incidentally discovered adrenal mass (incidentaloma):investigation and management of 208 patients 显示文摘Kasperlik-Zeluska AA Roslonowska E Slowinska-Srzednicka J 1997Clin Endocrinol1997,46,:2
5卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景 缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 2017国际脑血管病杂志2017,25,5:2
6Complications neuropathy:pathogenetic considerations显示文摘Greene DA Sima AA Stevens M J 0,,:2
7内皮细胞活化与高血压患者的认知功能有关显示文摘高血压与认知功能障碍和痴呆的发生有关,可能是因为高血压是引发脑损伤的一个重要危险因素,脑损伤是脑小血管病的一种表现。已发现内皮细胞活化和炎症在脑小血管病的发病机制中发挥重要作用。该研究调查以几种血管标志物为基础的内皮细胞活化或炎症的综合积分是否与原发性高血压患者3年后的认知功能有关。Uiterwijk R Huijts M Staals J Rouhl RP De Leeuw PW Kroon AA Van Oostenbrugge RJ 陈云 叶鹏 2016中华高血压杂志2016,24,6:2
8Epigenetic mechanism of growth inhibition induced by phenylhexyl isothiocyanate in prostate cancer cells显示文摘BEKLEMISHEVA AA FANG Y FENG J 2006Anticancer Res2006,26,2:1
9Elevated IGF- Ⅱ mRNA and phosphorylation of 4E-BP1 and p70^S6k in muscle showing elenbuterolinduced anabolism显示文摘Sneddon AA Delday MI Steven J 2001Am J Physiol Endocrinol Metab2001,281,:1
10Surgical treatment of venous malformations in Klippel-Trenaunay syndrome显示文摘Noel AA Gloviczki P Cherry Jr K J 2000J Vasc Surg2000,32,5:1
11pulmonary function after laparoscopic cholecystectomy显示文摘 Luna J Ghiatas AA 1993Surgery1993,114,:1
12Stryland Time-resolvedZ-scan measuremelRs of optical nonlinearties显示文摘 HEIK-BAHAE M SAID AA 1994Optical society of America1994,11,6:1
13Visualizing the kinetics of tumor-cell clearance in living animals显示文摘Sweeney T J Mailander V Tucker AA 1999Proc Natl Acad Sci USA1999,96,12:1
14An evaluation of potential mechanism-based in activation of human drug metabolizing cytochromes P450 by monoamine oxidase inhibitors, including isoniazid显示文摘Polasek TM Elliot D J Somogyi AA 2006Br J Clin Pharmacol2006,61,5:1
15Allergic rhinitis and its im- pact on asthma (ARIA)2008 update (in collaboration with the World Health Organization,GA(2)LEN and AllerGen)显示文摘Bousquet J Khaltaev N Cruz AA 2008Allergy2008,,:1
16Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003 显示文摘Dombrovskiy VY Martin AA Sunderram J 2007Crit Care Med2007,35,5:1
17Effect of transforming growth factor β1 on chondrogenic differentiation of cultured equine meseechymal stem cell显示文摘Worster AA Nixon A J Toland BD et cd 2000AJVR2000,61,9:1
18Use of antibodies to RCC and CD10 in the differential diagnosis of renal neoplasms显示文摘Avery AK Beckstead J Renshaw AA 2000Am J Surg Pathol2000,24,:1
19Cytokine-based tumor cell vaccine is equaly effective against parental and isogenic multidrug-resi stand myeloma cells,the role of cytotoxic T lymplocytes显示文摘Shtil AA Turner JG Durfee J 1999Blood1999,93,6:1
20Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues显示文摘Avilion AA Piatyszek MA Gupta J 1996Cancer Res1996,56,3:1
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