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| 1 | A comparison between previous and present histologic assessments of chronic hepatitis C viral infections in humans显示文摘METHODSLiverbiopsiesfrom79untreatedpatientswerereviewed.AntiHCVtestinghadbeenperformedbyELISAandconfirmedbyarecombinantimm... | N Assy 1 and GY Minuk 2 | 1999 | World Journal of Gastroenterology1999，5，2： | 24 |
| 2 | OPTICAL PROPERTIES OF GeO_2 AND Ge NANOCRYSTALS显示文摘he co m pound m aterial of n m size particles Ge O2 Si O2 w as synthesied through hydrolysis of Si( O C2 H4) and Ge Cl4 . A heat treatm ent w as carried out for the sa m ples at 100 ~1200 ℃in air . Its optical property w as deter mined by U V Vis spectur m . We have found that theabsorption edge of spectru m shifted progressively to longer w avelengths . The quantu m size ef fect of nanocrystals appears because crystals gro w and energy of optical band gap reduces d ueto the influence of te m perature . By the analysis of X ray diffraction w e have observed theprocess in w hich the structure of particles changed fro m disorder into order . | Y.H.Zhou 1) ,Y.Y.Feng 2) and H.Y.Lu 2) 1)Department of Physics Nanjing Normal University, Nanjing 210097,China 2)Physics and Ch寁O P T I C A L P R O P E R T I E S O F Ge O2 A N D Ge N A N O C R Y S T A L S Y. H. Zhou1) , Y. Y. Feng2) | 1999 | Acta Metallurgica Sinica(English Letters)1999，12，5： | 22 |
| 3 | Timing and geochemical characters of the Sanchazi magmatic arc in Mianlüe tectonic zone,South Qinling显示文摘The Sanchazi mafic-ultramafic complex in Mianlüe tectonic zone,South Qinling can be subdivided into two blocks,I.e.Sanchazi paleo-magmatic arc and Zhuangkegou paleo-oceanic crust fragment (ophiolite).The Sanchazi paleo-magmatic arc is mainly composed of ande-site,basaltic and basalt-andesitic gabbro(or diorite),andesitic dyke,plagiogranite and minor ul-tramafric rocks,which have typical geochemical features of island arc volcanic rocks,such as high field strength element(e.g.Nb,Ti)depletions and lower Cr,Ni contents.The Light rare earth element (LREE) and K enrichments of these rocks and zircon xenocrystals of 900 Ma from plagiogranite suggest that this magmatic arc was developed on the South active continental margin of the South Qinling micro-continent.The U-Pb age of (300±61) Ma for zircons from plagiogranite in-dicates that the Mianlüe paleo-oceanic crust was probably subducted underneath the South Qinling micro-continent in Carboniferous.This is consistent with the formation time (309Ma) of the Huwan eclogite originating form oceanic subduction in Dabie Mountains,suggesting that the Mianlüe paleo-ocean probably extended eastward to the Dabie Mountains in Carboniferous.The high-Mg adakitic rocks in Sanchazi paleo-magmatic arc suggest thet the subducted oceanic crust was relatively young (<25Ma) and hot. | LI Shuguang1, HOU Zhenhui1, YANG Yongcheng2, SUN Weidong1,1), ZHANG Guowei3, & LI Qiuli1 1. School of Earth and Space Sciences,University of Science and Technology of China ,Hefei 230026,China 2. Regional Geological Survey Team of Shaanxi Province,Xianyang 712000, China 3. Department of Geology, Northwest University,Xi抋n 710069, China | 2004 | Science China Earth Sciences2004，47，4： | 16 |
| 4 | Subclinical abnormal glucose tolerance is a predictor of death in liver cirrhosis显示文摘AIM:To determine if subclinical abnormal glucose tolerance(SAGT)has influence on survival of non-diabetic patients with liver cirrhosis.METHODS:In total,100 patients with compensatedliver cirrhosis and normal fasting plasma glucose were included.Fasting plasma insulin(FPI)levels were measured,and oral glucose tolerance test(OGTT)was performed.According to OGTT results two groups of patients were formed:those with normal glucose tolerance(NGT)and those with SAGT.Patients were followed every three months.The mean follow-up was932 d(range of 180-1925).Survival was analyzed by the Kaplan-Meyer method,and predictive factors of death were analyzed using the Cox proportional hazard regression model.RESULTS:Of the included patients,30 showed NGT and70 SAGT.Groups were significantly different only in age,INR,FPI and HOMA2-IR.Patients with SAGT showed lower 5-year cumulated survival than NGT patients(31.7%vs 71.6%,P=0.02).Differences in survival were significant only after 3 years of follow-up.SAGT,Child-Pugh B,and high Child-Pugh and Model for EndStage Liver Disease(MELD)scores were independent predictors of death.The causes of death in 90.3%of cases were due to complications related to liver disease.CONCLUSION:SAGT was associated with lower survival.SAGT,Child-Pugh B,and high Child-Pugh and MELD scores were independent negative predictors of survival. | Diego García-Compeán Joel Omar Jáquez-Quintana Fernando Javier Lavalle-González José Alberto González-González Linda Elsa Mu?oz-Espinosa Jesús Zacarías Villarreal-PérezEndocrinology Service and Department of Internal Medicine University Hospital 'Dr. José E. González' and Medical School Universidad Autónoma de Nuevo León Monterrey 64320 México Héctor J Maldonado-Garza | 2014 | World Journal of Gastroenterology2014，20，22： | 12 |
| 5 | Inflammatory bowel disease in Hubei Province of China显示文摘InflammatoryboweldiseaseinHubeiProvinceofChinaXIABing1,S.SHIVANANDA2,ZHANGGuiShui1,YIJiYun1,JBACRUSIUS3andASPEN~A3Subjecthe... | XIA Bing 1, S. SHIVANANDA 2, ZHANG Gui Shui 1, YI Ji Yun 1, JBA CRUSIUS 3 and AS PE N~ A 3 | 1997 | World Journal of Gastroenterology1997，3，2： | 12 |
| 6 | A paleontological perspective of vertebrate origin显示文摘The Early Cambrian Haikouichthys and Haikouella have been claimed to be related to contribute in an important way to our understanding of vertebrate origin, but there have been heated debates about how exactly they are to be interpreted. New discoveries of numerous speci-mens of Haikouichthys not only confirm the identity of pre-viously described structures such as the dorsal and the ven-tral fins, and chevron-shaped myomeres, but also reveal many new important characteristics, including sensory or-gans of the head (e.g. large eyes), and a prominent notochord with differentiated vertebral elements. This 揻irst fish?ap-pears, however, to retain primitive reproductive features of acraniates, suggesting that it is a stem-group craniates. A new order (Myllokunmingiida) and a new family (Myllo-kunmingiidae) are erected, and a new species, Zhongjianich-thys rostratus (gen. et sp. nov.), is described herein. Over 1400 newly-discovered specimens of Haikouella provide a wealth of anatomical information on this organism. It differs from chordates in many organs and organ systems, including the skin, muscles, respiratory, circulatory and nervous sys-tems. In contrast, its body-design resembles that of vetuli-colians, and the presence of a 搕ransitional?nervous system with both dorsal and ventral nerve cords suggests an affinity with living hemichordates. On the basis of these and other recent findings of fossil deuterostomes, a five-step hypothesis for vertebrate origin is proposed, intended to bridge the long- standing gap between protostomes and vertebrates. Four of the five steps accord with established ideas current in modern evolutionary zoology. Evidence for the first step is obtainable only from fossils, and specifically from fossils found from South China, hence the crucial importance of S. China sites for our understanding of early vertebrate origins and evolution. Accordingly, South China is suggested as the oldest-known birthplace of the whole vertebrates. | SHU Degan Early Life Institute & Department of Geology, Northwest University, Xi抋n, 710069, China School of Earth Sciences and Resources, China University of Geosciences, Beijing, 100083, China (e-mail: elidgshu@ nwn.edu.cn) | 2003 | Chinese Science Bulletin2003，48，8： | 11 |
| 7 | SWR1 Chromatin-Remodeling Complex Subunits and H2A.Z Have Non-overlapping Functions in Immunity and Gene Regulation in Arabidopsis显示文摘进由改变建筑群的 SWR1 染色质的 nucleosomes 的 histone 变体 H2A.Z 的加入是在真核细胞的基因规定的关键步。在 Arabidopsis, SWR1c 和 H2A.Z 被显示了控制位于开发和环境回答下面的基因表示。尽管他们在防卫被含有,在免疫的复杂子单元和 H2A.Z 的特定的角色很好没被理解。在这研究,我们分析了 SWR1c 子单元,光周期无关的早 FLOWERING1 (PIE1 ) ,肌动朊相关的 PROTEIN6 (ARP6 ) ,和 SWR1 建筑群的角色 6 (SWC6 ) ,以及 H2A.Z,在防卫和基因规定。我们发现 SWR1c 部件在抵抗起不同作用到不同病原体。PIE1 和 SWC6 功能以及 H2A.Z 的弄空的损失导致了减少的基础抵抗,当 ARP6 fucntion 的损失导致了提高的抵抗时。我们发现在 PIE1 和 SWC6 的变化导致了损害被触发受动器的免疫。在 SWR1c 部件和 H2A.Z 的变化也导致了损害 jasmonic acid/ethylene-mediated 免疫。染色体宽的表示分析同样在基因规定为 H2A.Z 和 SWR1c 部件揭示不同角色,并且在在表明小径的防卫之间的生气谈话的规定为 PIE1 建议一个潜在的角色。我们数据表演尽管他们是一样的建筑群的部分, Arabidopsis SWR1c 部件能在植物免疫和基因规定有非冗余的函数。 | Souha Berriri Sreeramaiah N Gangappa and S Vinod Kumar | 2016 | Molecular Plant2016，9，7： | 7 |
| 8 | Comparison of eastern paleo-Tethyan ophiolites and its geodynamic significance--Evidence from Dur'ngoi ophiolite显示文摘Nd-Pb isotopic geochemistry of metabasalt from Dur抧goi ophiolite, Qinghai Prov-ince, NW China reveals the presence of DMM mixing with EMII components in its upper mantle source, which is comparable with present Indian MORB. Comparisons indicate that the geo-chemistry, chronology and source characteristics of Dur抧goi ophiolite coincide with Pa-leo-tethyan ophiolites from 揝anjiang?area. Together with evidences from regional geology in adjacent areas, this study proves that independent paleo-tethyan basins evolved contemporarily, the dynamics of which is attributed to the interaction of mantle plume with over-riding lithosphere. | CHEN Liang1,2, SUN Yong1,2, PEI Xianzhi2, Feng Tao2 & Zhang Guowei2 1. Open Laboratory of Continental Dynamics, Ministry of Education, Northwest University, Xi抋n 710069, China 2. Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100029, China | 2004 | Science China Earth Sciences2004，47，4： | 7 |
| 9 | Appearance of an inhibitory cell nuclear antigen in rat and human serum during variable degrees of hepatic regenerative activity显示文摘METHODSInanimalstudies,adultmaleSpragueDawleyrats(n=3-4/group)weresacrificedat0,12,24,36,48,72and96hoursfollowing70%partia... | N Assy 1,2 ,YW Gong 3,M Zhang 3 and GY Minuk 3,4 | 1999 | World Journal of Gastroenterology1999，5，2： | 6 |
| 10 | Sufficient Conditions of Robust Schur Stability for Uncertain 2-D Polynomials | XIAO Yang\+1\ \ DU Xi\|yu\+1\ \ Rolf Unbehauen\+2 1.Institute of Information Science, Northern Jiaotong University Beijing 100044, P.R.China 2. Institute of General and Theoretic Electronic\|Technique University of Erlangen\|Nürnberg Cauerstr.7, 910 | 1999 | Systems Science and Systems Engineering1999，9，3： | 4 |
| 11 | HIGH-ENERGY IONS PRODUCED IN EXPLOSIONS OF SUPERHEATED ATOMIC CLUSTERS显示文摘 | T Ditmire J W G Tisch E Springate M B Mason N Hay R A Smith J Marangos and M H R Hutchinson | | 0，，： | 4 |
| 12 | Enhancement of the fertilizer value of rock phosphate engineered through phosphate- solubilizing bacteria显示文摘 | Sahu S N and Jana B B | 2000 | Ecol Engineering2000，15，： | 3 |
| 13 | Analysis of species-dependent hydrolysis and protein binding of esmolol enantiomers显示文摘The stereoselective hydrolysis of esmolol in whole blood and in its separated components from rat,rabbit and human was investigated.Blood esterase activities were variable in different species in the order of rat>rabbit>human.Rat plasma showed the high esterase activity and had no stereoselectivity to enantiomers.Rabbit red blood cell(RBC) membrane,RBC cytosol and plasma all hydrolyzed esmolol but with different esterase activity,whereas the hydrolysis in RBC membrane and cytosol showed significant stereoselectivity towards R-(+)-esmolol.Esterase in RBC cytosol from human blood mainly contributed to the esmolol hydrolysis,which was demonstrated with no stereoselctivity.Esterase in human plasma showed a low activity,but a remarkable stereoselectivity with R-(+)-esmolol.In addition,the protein concentration affected the hydrolysis behavior of esmolol in RBC suspension.Protein binding of esmolol enantiomers in human plasma,human serum albumin(HSA) and α_1-acid glycoprotein(AGP) revealed that there was a significant difference in bound fractions between two enantiomers,especially for AGP.Our results indicated that the stereoselective protein binding might play a role in the different hydrolysis rates of esmolol enantiomers in human plasma. | Yi-Hong Tanga,b,1,Jun-Yan Wanga,1,Hai-Hong Hua,Tong-Wei Yaoa,Su Zenga,n aDepartment of Pharmaceutical Analysis and Drug Metabolism,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou,Zhejiang 310058,People’s Republic of China bShanghai Institute of Technology,Shanghai 201418,People’s Republic of China | 2012 | Journal of Pharmaceutical Analysis2012，2，3： | 3 |
| 14 | Color 3D Reverse Engineering显示文摘This paper presents a principle and a method of col or 3D laser scanning measurement. Based on the fundamental monochrome 3D measureme nt study, color information capture, color texture mapping, coordinate computati on and other techniques are performed to achieve color 3D measurement. The syste m is designed and composed of a line laser light emitter, one color CCD camera, a motor-driven rotary filter, a circuit card and a computer. Two steps in captu ring object’s images in the measurement process: First, the color CCD camera ta kes the color picture of the object to be used for texture mapping in post proce ssing. Secondly, the monochrome data of the object is taken. The laser light emi tter is started; the light plane and the surface of the object intersect to form an undulate line, which forms an image on the CCD sensor. After the optic- electronics transformation, the electronic signals are captured and send to the computer. A new color 3D measurement model was derived, and a rapid calibra ting method to measure the system parameters was proposed--optical plane equat ion calibrating method. A calibrating drone was designed and built. 3D color sca nning system not only provides an object’s individual point information in the 3D coordinate, in the mean time, it provides the color information of each indiv idual point. This paper also advances a multi-frame auto-merging method, i.e. several frames of color 3D digital images measured are merged quickly according to their curvature characteristics and RGB information. Initial matching and fin e tune of the registration are completely performed by the computer; initial mat ching is via user interface in helping computer to find the transformation matri x. The transformation matrix is found according to the geometric characteristics chosen by hand. After the initial transformation matrix is found, fine tune of the registration is preformed to do the optimum adjustment to achieve a complete color textured 3D model. The system can be broadly used in the fields of produc t design, mold manufacture, multimedia, game development, animation, medical eng ineering, antique digitization, etc. | XU Zhi-qin 1, YE Sheng-hua 1, FAN Guang-zhao 2 (1. School of Precision Instrument and Opto-electronics Engineering, N ational Key Lab of Measurement Technology and Instrument, EMC, Tianjin University, Tianjin, China 2. Department of Mechanical Engineering, National Taiwan University, Taiwan, Chi na) | 2002 | 厦门大学学报(自然科学版)2002，41，S1： | 3 |
| 15 | Immobilized enzyme reactors in HPLC and its application in inhibitor screening:A review显示文摘This paper sets out to summarize the literatures based on immobilized enzyme bio-chromatography and its application in inhibitors screening in the last decade.In order to screen enzyme inhibitors from a mass of compounds in preliminary screening,multi-pore materials with good biocompatibility are used for the supports of immobilizing enzymes,and then the immobilized enzyme reactor applied as the immobilized enzyme stationary phase in HPLC.Therefore,a technology platform of high throughput screening is gradually established to screen the enzyme inhibitors as new anti-tumor drugs.Here,we briefly summarize the selective methods of supports,immobilization techniques,co-immobilized enzymes system and the screening model. | Si-Meng Fang a,Hai-Na Wang a,Zhong-Xi Zhao b,Wei-Hong Wang a,n a School of Pharmaceutical Sciences,Shandong University,Ji’nan,China b School of Pharmaceutical Sciences and Center for Pharmaceutical Research & Drug Delivery Systems,Shandong University,Ji’nan,China | 2012 | Journal of Pharmaceutical Analysis2012，2，2： | 3 |
| 16 | A rapid method for estimating log P for organic chemicals显示文摘 | Veith G D Austin N M and Morris R T | 1979 | Water Res1979，13，： | 3 |
| 17 | A brief introduction to recent applications of several sediment-analysis techniques in palaeolimnological studies-dry bulk density and water content, mineral magnetism, carbonate content, and content of total organic carbon,nitrogen content and carbon/ni显示文摘Determination of dry bulk density and water content measurement of magnetic susceptibility (x) and saturation isothermal remanent magnetization (SIRM), determination of carbonate content, and determination of total organic carbon (TOC) content nitrogen content (N%) and carbon/nitrogen (C/N) ratio are some of the techniques which have been widely applied to lacustrine-sediment analyses. The techniques,complemented by others, are usually useful for revealing characteristics of lacustrine-sediments and thus for postulating hydrological regimes in the lake and environmental conditions and human activity around it in palaeolimnological studies. A very brief review is presented on recent applications of these techniques in palaeolimnological work with English literatures published mainly since 1985 and focus given on interpretations of results of these analyses related to palaeoenvironmental reconstructions. Low dry bulk density and high water content often imply relatively warm and wet conditions. High X and SIRM are usually resulted from reduced dilutions in the lake and intensified erosions on its catchment. both of which can be in turn attributed to environmental changes. While variations in patterns of X and SIRM may give further insight on mineral magnetism and thus implications on environmental conditions. Increased carbonate content seems likely to associate to warm and dry conditions.Increased TOC content is virtually used as one of indicators of warm and wet conditions and variations in C/N ratio may hint variations in relative contributions of different sources, aquatic and terrestrial, to the total organic matter in lake sediments and hence to lake-level fluctuations and climate changes. | WANG Hong-ya (Dept. of Urban and Environmental Sciences, Peking University, Beijing 100871, China Geophysical Laboratory, Dot. of Earth Sciences, University of Aarhus, Finlandsgade 8. DK- 8200, Aarhus N, Denmark) | 2000 | Journal of Geographical Sciences2000，10，1： | 2 |
| 18 | Evaluation and Optimization of DNA Extraction and Purification Procedures for Soil and Sediment Samples 显示文摘 | D N Miller J E Bryant E L Madsen and W C Ghiorse | 1999 | Applied and environmental Microbiolog1999，65，： | 2 |
| 19 | Fundamental characteristics of multiple tuned mass dampers for suppressing harmonically forced oscillators 显示文摘 | Yamaguchi H and Harnporuchai N | 1993 | Earthquake Engineering and Structural Dynamics1993，22，： | 2 |
| 20 | The contourlet transform: an efficient directional multiresolution image representation显示文摘 | Do M N and Vetterli M | 2005 | IEEE Transactions on Image Processing2005，14，12： | 2 |
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