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| 1 | Presence of Antibodies to Heat Stress Proteins and its Possible Significance in Workers Exposed to High Temperature and Carbon Monoxide显示文摘Antibodies to the ubiquitous group of stress proteins known as heat shock proteins (Hsps) have been found to be associated with a number of diseases in humans. Hsps are known to be induced by certain xenobiotics, some of which are common in the working environment. The biological significance of the presence of such autoantibodies is presently unclear. In the present study, we used immunoblotting to investigate the presence of antibodies against the different stress proteins, Hsp27, Hsp60, Hsp71, Hse (heat shock cognate ) 73 and Hsp89a and D in groups of workers exposed to high temperature or carbon monoxide. These data were related to a detailed clinical evaluation and to various laboratory measurements including electrocardiogram (ECG), B echogram, white blood cell counts and typing, the activity of alanine aminotransferase (ALT), acid phosphatase (ACP) and alkaline phosphatase (ALP) and lymphocyte DNA damage. Antibodies to Hsp27 and Hsp71 were found more frequently in the high temperature and carbon monoxide-exposed groups than in controls (P (0.05 ). The carbon monoxide-exposed group showed the highest incidence of anti-Hsp antibodies. Anti-Hsp60 antibodies were only detected in workers exposed to high temperature or carbon monoxide. The percentage of workers with abnormal ECG, B echogram changes and displaying hepatitis B antigen (HBsAg ) was higher in the carbon monoxide group than in the control group (P<0.05 ).There was a significant inerease in the activity of ALT in the high temperature and carbon monoxide groups and in the activities of ACP and ALP in the carbon monoxide group (P<0.05 ). The extent of DNA damage measured in lymphoeytes was higher in workers from the high temperature and carbon monoxide-cxposed groups. We suggest that the increased frequeney of antibodies to Hsps is the result of these damages, of the release of denatured Hsps and of a decrease in the phagocytic ability of macrophages in these workers. The data gathered in the present study show a statistical relation between the occurrence of antibodies against Hsps and the frequency of health problems in workers and suggest a potential role for the antibodies as useful biomarkers to assess whether workers are experieneing environmental | WU TANG-CHUN TANGUAY, ROBERT M. WU YANG HE HAN-ZHEN XU DAI-GEN FENG JIA-DE SHI WU-XIANG AND ZHANG GUO-GAO (Institute of Occupational Medicine, Tongji Medical University, Wuhan 430040, China Centre de recherche du CHUL and Lab of Cellular and Develo | 1996 | Biomedical and Environmental Sciences1996，9，4： | 23 |
| 2 | 对骨折内固定术后早期感染者保留内固定物的策略显示文摘背景:开放复位内固定术后,在内固定物存在的情况下治疗伤口深部感染极为棘手,关于治疗方案的使用,文献报道甚少。本研究旨在探讨骨折内固定术后6周内发生感染后保留内固定物直至骨性愈合的可能性。方法:通过回顾3个I级创伤中心以往的病历和创伤登记表,共纳入121例新鲜骨折患者,这些患者术中细菌培养均为阳性,内固定术后6周内共123处创口发生感染。统计保留内固定物并获骨折愈合者的比率,评价预测其治疗成败的指标。结果:86例患者(87处骨折;71%)经手术清创、保留内固定物和敏感抗生素治疗获得骨折愈合。治疗失败的有关因素包括开放性骨折(p=0.03)和髓内钉固定(p=0.01)。其他非明显相关但有相关倾向的变量包括吸烟、假单胞菌感染以及累及股骨、胫骨、踝部或足部的骨折。结论:骨折内固定术后深部感染者可通过手术清创、敏感抗生素治疗及保留内固定物成功获得骨折愈合。这些结果可通过基于危险基因、特定菌种和有关的内固定种类对患者进行选择而获得改善。 | Marschall Berkes, MD William T. Obremskey, MD MPH, Brian Scannell, MD J. Kent Ellington, MD Robert A. Hymes, MD Michael Bosse, MD, and the Southeast Fracture Consortium 黄哲元(译) 丁真奇(译) | 2010 | 中华骨科杂志2010，30，9： | 21 |
| 3 | Preface显示文摘A supercomputer has been competitively ranked by its computing speed,memory and storage capacity,andparallel processing scalability year by year. | Xiao-Dong Zhang,Robert M.Critchfield Professor,Department of Computer Science and Engineering The Ohio State University,U.S.A. | 2011 | Journal of Computer Science & Technology2011，26，3： | 4 |
| 4 | A framework infrageneric classification of Carex (Cyperaceae) and its organizing principles显示文摘Phylogenetic studies of Carex L.(Cyperaceae)have consistently demonstrated that most subgenera and sections are para-or polyphyletic.Yet,taxonomists continue to use subgenera and sections in Carex classification.Why?The Global Carex Group(GCG)here takes the position that the historical and continued use of subgenera and sections serves to(i)organize our understanding of lineages in Carex,(ii)create an identification mechanism to break the~2000 species of Carex into manageable groups and stimulate its study,and(iii)provide a framework to recognize morphologically diagnosable lineages within Carex.Unfortunately,the current understanding of phylogenetic relationships in Carex is not yet sufficient for a global reclassification of the genus within a Linnean infrageneric(sectional)framework.Rather than leaving Carex classification in its current state,which is misleading and confusing,we here take the intermediate steps of implementing the recently revised subgeneric classification and using a combination of informally named clades and formally named sections to reflect the current state of our knowledge.This hybrid classification framework is presented in an order corresponding to a linear arrangement of the clades on a ladderized phylogeny,largely based on the recent phylogenies published by the GCG.It organizes Carex into six subgenera,which are,in turn,subdivided into 62 formally named Linnean sections plus 49 informal groups.This framework will serve as a roadmap for research on Carex phylogeny,enabling further development of a complete reclassification by presenting relevant morphological and geographical information on clades where possible and standardizing the use of formal sectional names. | Eric H.Roalson Pedro Jiménez-Mejías Andrew L.Hipp Carmen Benítez-Benítez Leo P.Bruederle Kyong-Sook Chung Marcial Escudero Bruce A.Ford Kerry Ford Sebastian Gebauer Berit Gehrke Marlene Hahn Muhammad Qasim Hayat Mathias H.Hoffmann Xiao-Feng Jin Sangtae Kim Isabel Larridon Étienne Léveillé-Bourret Yi-Fei Lu Modesto Luceño Enrique Maguilla Jose IgnacioMárquez-Corro Santiago Martín-Bravo Tomomi Masaki Mónica Míguez Robert F.C.Naczi Anton A.Reznicek Daniel Spalink Julian R.Starr Uzma Tamara Villaverde Marcia J.Waterway Karen L.Wilson and Shu-Ren Zhang | 2021 | Journal of Systematics and Evolution2021，59，4： | 3 |
| 5 | Gap filling strategies for long term energy flux data sets显示文摘 | Eva Falge Dennis Baldocchi Richard Olson Peter Anthoni Marc Aubinet Christian Bernhofer George Burba Reinhart Ceulemans Robert Clement Han Dolman André Granier Patrick Gross Thomas Grünwald David Hollinger Niels-Otto Jensen Gabriel Katul Petri Keronen And | 2001 | Agricultural and Forest Meteorology2001，，1： | 2 |
| 6 | Review on aggregation of acid extractants in solvent extraction of metal ions:remark on the general model显示文摘The aggregation behavior of various acid extractants in the solvent extraction systems of metal ions is re-examined and explained according to knowledge obtained in recent work. The conclusions are as follows. (1) Complexes formed by the extractants and metal ions can form reversed micelles in organic diluents, depending on the microstructures of the complexes. The dimers of the acid extractant cannot percolate to the metal-extractant aggregates, and the acid-salt complexes are always formed in the aggregates. The reversed micelles or the W/O microemulsions formed by different species cannot be associated with each other to form a unified aggregate. (2) In solvent extraction systems, hydration of the extractants and metal ions can be considered as the driving force of forming reversed micelles. (3) Information of the first approach to the insight of the bicontinuous microemulsion of NaDEHP shows that various components in the aqueous phase behave confined and very similar to the typical AOT/n-heptane W/O microemulsions. (4) In the extraction of lanthanide ions by the W/O microemulsion of sodium naphthenate, the saponification is a process of forming reversed micelle or W/O microemulsion, while the extraction step is a process of destroying reversed micelles or W/O microemulsion droplets. | ZHOU Naifu and WU Jinguang(Department of Chemistry, Peking University, Beijing 100871, China Charles S. Roberts Laboratory, Gilmer Tumham Building, Auburn 36830, USA) | 2003 | Progress in Natural Science:Materials International2003，13，1： | 2 |
| 7 | Pandemic influenza 2009: Impact of vaccination coverage on critical illness in children, a Canada and France observational study显示文摘AIM To study the impact of vaccination critical illness due to H1N1pdm09, we compared the incidence and severity of H1N1pdm09 infection in Canada and France.METHODS We studied two national cohorts that included children with documented H1N1pdm09 infection, admitted to a pediatric intensive care unit(PICU) in Canada and in France between October 1, 2009 and January 31, 2010.RESULTS Vaccination coverage prior to admission to PICUs was higher in Canada than in France(21% vs 2% of children respectively, P < 0.001), and in both countries, vaccination coverage prior to admission of these critically ill patients was substantially lower than in the general pediatric population(P < 0.001). In Canada, 160 children(incidence = 2.6/100000 children) were hospitalized in PICU compared to 125 children(incidence = 1.1/100000) in France(P < 0.001). Mortality rates were similar in Canada and France(4.4% vs 6.5%, P = 0.45, respectively), median invasive mechanical ventilation duration and mean PICU length of stay were shorter in Canada(4 d vs 6 d, P = 0.02 and 5.7 d vs 8.2 d, P = 0.03, respectively). H1N1pdm09 vaccination prior to PICU admission was associated with a decreased risk of requiring invasive mechanical ventilation(OR = 0.30, 95%CI: 0.11-0.83, P = 0.02).CONCLUSION The critical illness due to H1N1pdm09 had a higher incidence in Canada than in France. Critically ill children were less likely to have received vaccination prior to hospitalization in comparison to general population and children vaccinated had lower risk of ventilation. | Olivier Fléchelles Olivier Brissaud Robert Fowler Thierry Ducruet Philippe Jouvet the Pediatric Canadian Critical Care Trials Group H1N1 Collaborative and Groupe Francophone de Réanimation et Urgences Pédiatriques | 2016 | World Journal of Clinical Pediatrics2016，5，4： | 2 |
| 8 | Macroinvertebrate assemblages of surface mine wetlands of Southwest Virginia,USA显示文摘MacroinvertebrateassemblagesofsurfaceminewetlandsofSouthwestVirginia,USA￥DavidH.Jones;RobertB.Atkinson;JohnCairns,Jr.(Departm... | David H.Jones Robert B. Atkinson John Cairns,Jr.(Department of Biology,Virginia Polytechnic Institute and State University, Blacksburg,Virginia 24061 USA) | 1996 | Journal of Environmental Sciences1996，8，1： | 2 |
| 9 | PRIMARY CELL CULTURE FOR EMBRYONIC CARDIAC MYOCYTES OF MEXICAN AXOLOTL AND DISTRIBUTION OF DESMIN AND VIMENTIN显示文摘INTRODUCTIONTheaxolotlprovidesavaluablemodelsystemforstudyingmuscledevelopmentandfunction.Electronmicroscopyrevealsthataxolot... | Zhu Yongze, Robert W Zajdel *, Margaret E Fransen *, Larry F Lemanski *(Department of Anatomy, Medical College of Yangzhou University, Yangzhou, 225001 Chian Department of Anatomy and Cell Biology, State University of New York, Health Science Cent | 1999 | 中国组织化学与细胞化学杂志1999，8，1： | 2 |
| 10 | Metallurgy, the Father of Materials Science显示文摘The evolution of the discipline of materials science during the second half of the twentieth century is outlined. The concept emerged in the USA, almost simultaneously in an academic metallurgy department and in an avant garde industrial research laboratory, and its development subsequently all over the world has been a joint enterprise involving universities, industrial laboratories and government establishments. The initial impetus came unambiguously from the well established discipline of physical metallurgy, but from the 1960s onwards, the input from solid state physicists grew very rapidly, while materials chemistry is a later addition. Of all the many subdivisions of modern materials science, polymer science has been the slowest to fit under the umbrella of the broad discipline; its concepts are very different from those familiar to metallurgists. Two fields have contributed mightily to the creation of modern materials science: One is nuclear energy and, more specifically, the study of radiation damage, the other is the huge field of electronic and opto electronic materials in which physics, chemistry and metallurgy are seamlessly combined. | Robert W. CahnDepartment of Metallurgy and Materials Science, Cambridge University, Pembroke Street, Cambridge CB2 3QZ, UK | 2002 | Tsinghua Science and Technology2002，7，1： | 2 |
| 11 | Conflict and Power-Dependence Relations in Retailer-Supplier Channels 显示文摘 | James R Brown Robert F Lusch and Darrel D Muehling | 1983 | Journal of Retailing1983，59，4： | 1 |
| 12 | Law and Finance显示文摘 | Rafael La Port Florencio Lopez-de-Silanes Andrei Shleifer and Robert Vishny | 1998 | Journal of Political Economy1998，106，6： | 1 |
| 13 | Moral Hazard In Home Equity Conversion显示文摘 | Robert J shiller and Allan N Weiss | 2000 | Real Estate Economics2000，，1： | 1 |
| 14 | Relational contracts and the theory of the firm 显示文摘 | Baker George Gibbons Robert and Murphy Kevin J | 2002 | Quarterly Journal of Econimics2002，117，1： | 1 |
| 15 | Developing Country Exports of Manufactures: Moving up the Ladder to Escape the Fallacy of Composition显示文摘 | Razmi Arslan and Blecker Robert | 2008 | The Journal of Development Studies2008，44，1： | 1 |
| 16 | Co - inte- gration and Error Correction : Representation, Estima- tion, and Testing 显示文摘 | ENGLE ROBERT F and GRANGER C W J | 1987 | Econimetrica1987，，2： | 1 |
| 17 | Role Conflict and Ambiguity in Complex Organizations显示文摘 | John R Rizzo Robert J House and Sidney I Lirtzman | 1970 | Administrative Science Quarterly1970，15，02： | 1 |
| 18 | LiquidationValues and Debt Capacity:A Market Equilibrium Approach显示文摘 | Shleifer Andrei and Vishny Robert W | 1992 | Finance 47(September 1992)1992，13，： | 1 |
| 19 | 显示文摘 | Tremblay JJ Robert NM and Viger RS | 2001 | Mol Endocrinol2001，15，9： | 1 |
| 20 | Employee research is a powerful tool in leading the time-based organization显示文摘 | Roberts D R and Rollins T | 1995 | Employee Relations Today1995，22，4： | 1 |
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