|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 对骨折内固定术后早期感染者保留内固定物的策略显示文摘背景:开放复位内固定术后,在内固定物存在的情况下治疗伤口深部感染极为棘手,关于治疗方案的使用,文献报道甚少。本研究旨在探讨骨折内固定术后6周内发生感染后保留内固定物直至骨性愈合的可能性。方法:通过回顾3个I级创伤中心以往的病历和创伤登记表,共纳入121例新鲜骨折患者,这些患者术中细菌培养均为阳性,内固定术后6周内共123处创口发生感染。统计保留内固定物并获骨折愈合者的比率,评价预测其治疗成败的指标。结果:86例患者(87处骨折;71%)经手术清创、保留内固定物和敏感抗生素治疗获得骨折愈合。治疗失败的有关因素包括开放性骨折(p=0.03)和髓内钉固定(p=0.01)。其他非明显相关但有相关倾向的变量包括吸烟、假单胞菌感染以及累及股骨、胫骨、踝部或足部的骨折。结论:骨折内固定术后深部感染者可通过手术清创、敏感抗生素治疗及保留内固定物成功获得骨折愈合。这些结果可通过基于危险基因、特定菌种和有关的内固定种类对患者进行选择而获得改善。 | Marschall Berkes, MD William T. Obremskey, MD MPH, Brian Scannell, MD J. Kent Ellington, MD Robert A. Hymes, MD Michael Bosse, MD, and the Southeast Fracture Consortium 黄哲元(译) 丁真奇(译) | 2010 | 中华骨科杂志2010，30，9： | 21 |
| 2 | 中国太湖1950年以来主要环境的变化和迅速富营养化的开始显示文摘太湖是我国第三大淡水湖,面积2350km2,位于长江三角洲(面积35000km2)的中部,自6000年前太湖形成以来,湖泊经历了几个主要变化。1950年以前,太湖最明显的变化发生在海侵和湖盆大小。海侵是太湖形成的主要原因。太湖形成后,在不同的干燥和湿润时期,湖盆经历了由一系列的小湖或统一湖盆之间的波动。但一般来说,近2000年以来,湖盆的大小在增大。然而1950年以后,为适应人口的增长,许多浅水地带被改造成农田和鱼塘。50年代以来,对湖盆和流域的进一步利用导致湖泊发生了一些变化。在这个阶段太湖的主要变化是:1)对排水流域、湖泊生态和营养状况具有重大影响的堤坝的修筑和湖岸的改造;2)始于1983/1984年湖泊的迅速富营养化。湖泊迅速富营养化的主要原因是由于工业、农业和城市化的迅速增长,导致未经处理的废水排入湖盆。每年这些营养物大量排入,对湖泊的营养状况影响甚重,在低水位时尤其如此。 | William Y.B.Chang(Center for Great Lakes and Aquatic Sciences and School of Natural Resources and Environment,the University of Michigan,Ann Arbor,Michigan 48109,U.S.A.andDivision of International Programs National Science Foundation,Foundation,Arlington, | 1996 | 古生物学报1996，35，2： | 8 |
| 3 | Comprehensive analysis of results of surgical treatment of oraltongue carcinoma in Hong Kong显示文摘ComprehensiveanalysisofresultsofsurgicaltreatmentoforaltonguecarcinomainHongKongPoWingYuen,WiliamI.Wei,YueMingWong,KwongChiTa... | Po Wing Yuen, William I. Wei, Yue Ming Wong, Kwong Chi Tang and Lai Kun Lam | 1997 | Chinese Medical Journal1997，，11： | 3 |
| 4 | Motion signal processing 显示文摘 | Armin Bruderlin and Lance Williams | 1995 | Proceeding of SIGGRAPH 95 Computer Graphics Proceedings Annual Conference Series August 19951995，29，： | 2 |
| 5 | The Cooperative Activities of CSLD2, CSLD3, and CSLD5 Are Required for Normal Arabidopsis Development显示文摘Glycosyltransferases of the Cellulose Synthase Like D (CSLD) subfamily have been reported to be involved in tip growth and stem development in Arabidopsis. The csld2 and csld3 mutants are root hair defective and the csld5 mutant has reduced stem growth. In this study, we produced double and triple knockout mutants of CSLD2, CSLD3, and CSLD5. Unlike the single mutants and the csld2/csld3 double mutant, the csld2/csld5, csld3/csld5, and csld2/ csld3/csld5 mutants were dwarfed and showed severely reduced viability. This demonstrates that the cooperative activities of CSLD2, CSLD3, and CSLD5 are required for normal Arabidopsis development, and that they are involved in important processes besides the specialized role in tip growth. The mutant phenotypes indicate that CSLD2 and CSLD3 have overlapping functions with CSLD5 in early plant development, whereas the CSLD2 and CSLD3 proteins are non-redundant. To determine the biochemical function of CSLD proteins, we used transient expression in tobacco leaves. Microsomes containing heterologously expressed CSLD5 transferred mannose from GDP–mannose onto endogenous acceptors. The same activity was detected when CSLD2 and CSLD3 were co-expressed but not when they were expressed separately. With monosaccharides as exogenous acceptors, microsomal preparations from CSLD5-expressing plants mediated the transfer of mannose from GDP–mannose onto mannose. These results were supported by immunodetection studies that showed reduced levels of a mannan epitope in the cell walls of stem interfascicular fibers and xylem vessels of the csld2/csld3/csld5 mutant. | Lan Yin Yves Verhertbruggen Ai Oikawa Chithra Manisseri Bernhard Knierim Lina Prak Jacob Kriiger Jensen Paul Knox Manfred Auer William G.T. Willatsa and Henrik Vibe Scheller | 2011 | Molecular Plant2011，4，6： | 2 |
| 6 | Mammalian microsomal cytochrome P450 monooxygenes: structure adaptation for membrane binding and functional diversity显示文摘 | Williams PA and Mcree DE | 2000 | Mol Cell2000，5，： | 1 |
| 7 | Friendship within entrepreneurial teams and its association with team and venture performance显示文摘 | Deborah H Frances and William R Sandberg | 2000 | Entrepreneurship Theory and Practice2000，25，2： | 1 |
| 8 | Domains and Image Schemas显示文摘 | Clausner Timothy and William Croft | 1999 | Cognitive linguistics1999，，10： | 1 |
| 9 | Theory of the firm:Managerial behavior,agency costs,and ownership structure显示文摘 | Jensen Michael and William Meckling | 1976 | Journal of Financial Economics1976，，3： | 1 |
| 10 | Personnel flows as in-ter-organizational relations 显示文摘 | Baty G William M and Rothermel T | 1971 | Administrative Science Quar-terly1971，16，： | 1 |
| 11 | Theory of The Firms: Managerial Behavior Agency Costs and Owmership Structure 显示文摘 | Jensen Michael C and William H Meckling | 1976 | Journal of Financial Economics1976，，3： | 1 |
| 12 | Analysts' forecasts as proxies for investor beliefs in empirical research 显示文摘 | Jeffery S Abarbanel William N Lanen and Robert E Ver- recchia | 1995 | Journal of Accounting and Eco- nomics1995，20，： | 1 |
| 13 | Work group demography,social integration,and turnover显示文摘 | O'Reilly Charles A III David F Caldwell and William P Barnett | 1989 | Administrative Science Quarterly1989，，34： | 1 |
| 14 | An investigation of polymorphism in the interleukin - 10 gene promoter 显示文摘 | Turner D M Williams D M Sankaran D Lazams M Sinnott P J and Hutchinson 1 V | 1997 | Eur J Immunogenet1997，24，： | 1 |
| 15 | The Impact of Channel Leadership Behavior on Intrachannel Conflict 显示文摘 | Patrick L Schul William M Pride and Taylor L Little | 1983 | Journal of Marketing1983，47，3： | 1 |
| 16 | Changes in sympathoadrenal responses to standing in humans after space flight显示文摘 | JB Charles and WJ Williams | 1995 | J Appl Physiol1995，79，： | 1 |
| 17 | 'The Evolution of macro models at the Federal Reserve Board' 显示文摘 | Flint Levin Andrew Tryon Ralph and Williams John C | 1997 | Carnegie-Roehester Conference Series on Public Policy 471997，，47： | 1 |
| 18 | Multiresidue Determination of Acidic Pesticides in Water by HPLC-DAD with Confirmation by GC-MS Using Conversion to the Methyl Ester with Trimethylsilyldiazomethane显示文摘 | | 2003 | J Chromatogra Sci2003，41，： | 1 |
| 19 | An improved spatial smoothing technique for bearing estimation in multipath environment显示文摘 | Williams R Prasad S Mahalanabis A and Sibul L | 1988 | IEEE Trans on ASSP1988，36，4： | 1 |
| 20 | Strong correlation of major earthquake with solid-earth tides in part of the eastern United States 显示文摘 | Robert E Weems and William H Perry | 1989 | Geology1989，17，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员