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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | 冠状动脉内影像学临床应用专家共识(第一部分):对冠状动脉介入治疗的指导与优化显示文摘欧洲心血管介入协会(EAPCI)专家组系统总结了血管内超声(IVUS)和光学相干断层成像(OCT)这两种血管内影像学检查临床应用指征的现有证据,提供了关于IVUS和OCT指导经皮冠状动脉介入治疗(PCI)的应用价值,并明确了最可能从腔内影像学指导的介入治疗中获得临床收益的患者或病变类型,同时详细论述了PCI前如何使用IVUS或OCT优化支架尺寸(支架长度和直径)和手术策略的选择。此外,专家推荐对支架失败(支架内再狭窄或支架内血栓形成)的患者应常规进行冠状动脉内影像学检查,并首选OCT。最后,重点论述了IVUS和OCT在指导PCI和评估支架失败两个方面的优势和局限性,并对未来需要深入研究的领域进行了展望。 | Lorenz Raber Gary S Mintz Konstantinos C Koskinas Thomas W Johnson Niels R Holm Yoshinubo Onuma Maria D Radu Michael Joner Bo Yu Haibo Jia Nicolas Meneveau Jose M.de la Torre Hemandez Javier Escaned Jonathan Hill Francesco Prati Antonio Colombo Carlo di Mario Evelyn Regar Davide Capodanno William Wijns Robert A Byme Giulio Guagliumi | 2019 | 中华心血管病杂志2019，47，1： | 17 |
| 3 | Mapping aboveground biomass and its prediction uncertainty using LiDAR and field data, accounting for tree-level allometric and LiDAR model errors显示文摘Background: The increasing availability of remotely sensed data has recently challenged the traditional way of performing forest inventories, and induced an interest in model-based inference. Like traditional design-based inference, model-based inference allows for regional estimates of totals and means, but in addition for wall-to-wall mapping of forest characteristics. Recently Light Detection and Ranging(LiDAR)-based maps of forest attributes have been developed in many countries and been well received by users due to their accurate spatial representation of forest resources. However, the correspondence between such mapping and model-based inference is seldom appreciated. In this study we applied hierarchical model-based inference to produce aboveground biomass maps as well as maps of the corresponding prediction uncertainties with the same spatial resolution. Further, an estimator of mean biomass at regional level, and its uncertainty, was developed to demonstrate how mapping and regional level assessment can be combined within the framework of model-based inference.Results: Through a new version of hierarchical model-based estimation, allowing models to be nonlinear, we accounted for uncertainties in both the individual tree-level biomass models and the models linking plot level biomass predictions with LiDAR metrics. In a 5005 km2 large study area in south-central Sweden the predicted aboveground biomass at the level of 18 m×18 m map units was found to range between 9 and 447 Mg·ha^-1. The corresponding root mean square errors ranged between 10 and 162 Mg·ha^-1. For the entire study region, the mean aboveground biomass was 55 Mg·ha^-1 and the corresponding relative root mean square error 8%. At this level 75%of the mean square error was due to the uncertainty associated with tree-level models.Conclusions: Through the proposed method it is possible to link mapping and estimation within the framework of model-based inference. Uncertainties in both tree-level biomass models and models linking plot level biomass with LiDAR data are accounted for, both for the uncertainty maps and the overall estimates. The development of hierarchical model-based inference to handle nonlinear models was an important prerequisite for the study. | Svetlana Saarela AndréWästlund Emma Holmström Alex Appiah Mensah Sören Holm Mats Nilsson Jonas Fridman Göran Ståhl | 2020 | Forest Ecosystems2020，7，3： | 3 |
| 4 | Application of the generalized Pareto distribution to extreme value analysis in wind engineering显示文摘 | Holmes J D Moriarty W W | 1999 | Journal of Wind Engineering and Industrial Aerodynamics1999，83，13： | 2 |
| 5 | Electroluminescence in conjugated polymers 显示文摘 | FRIEND R H GYMER R W HOLMES A B | 1999 | Nature1999，397，： | 2 |
| 6 | 与久坐者相比,职业运动员的肠道菌群在代谢组分,尤其是功能代谢水平上有所不同显示文摘目的有证据表明肠道菌群以及影响其结构和活性的因素在人类代谢、免疫和发育过程中发挥作用。我们曾报道,与久坐者相比,诸如职业运动员,配有相应饮食的极度体育活动者肠道菌群种属和代谢组分发生了改变。这次我们重点研究这些因素对菌群功能/代谢活动的影响,以进一步揭示运动者和久坐者间的差别。方法对专业国际橄榄球联盟球员(样本数为40例)和对照(样本数为46例)的肠道菌群进行代谢表型和功能宏基因组分析,并将结果与生活方式指标(比如饮食习惯)和临床评估指标(比如血清肌酸激酶)进行关联。结果与对照相比,运动员组中与肌肉更新和整体健康相关的信号通路(比如:氨基酸、抗生素生物合成和碳水化合物代谢)和肠道菌群代谢产物(比如:短链脂肪酸乙酸酯、丙酸酯和丁酸酯)有所增加。结论运动和久坐相比,其肠道菌群在宏基因组和代谢组学上比组织水平显示出更大差异,拓展了饮食.运动.肠道微生态模式新视野。 | Barton W Penney NC Cronin O Garcia-Perez I Molloy MG Holmes E Shanahan F Cotter PD O'Sullivan O 毛玲娜 宋震亚 | 2017 | 英国医学杂志中文版2017，20，7： | 2 |
| 7 | Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial显示文摘 | Friedrich W Mohr Marie-Claude Morice A Pieter Kappetein Ted E Feldman Elisabeth St?hle Antonio Colombo Michael J Mack David R Holmes Marie-angèle Morel Nic Van Dyck Vicki M Houle Keith D Dawkins Patrick W Serruys | 2013 | The Lancet . 2013 (9867)2013，，9867： | 2 |
| 8 | A Unified Approach to Clenshaw Summation and the Recursive Computation of Very High Degree and Order Normalized Associated Legendre Functions显示文摘 | Holmes S A Featherstone W E | 2002 | Journal of Geodesy2002，76，： | 1 |
| 9 | Relative fitness of imazalil- resistant and-sensitive biotypes of Penicillium digitatum 显示文摘 | HOLMES G J ECKERT J W | 1995 | Plant Dis1995，79，： | 1 |
| 10 | A periodically forced Impact oscillator with large dissipation显示文摘 | Shaw S W Holmes P J | 1983 | Journal of Applied Mechanics1983，50，： | 1 |
| 11 | Passivity-Based Control of Bipedal Locomotion 显示文摘 | Spong M W Holm J K Dongjun Lee | 2007 | IEEE Robotics & Automation Magazine (S1070-9932)2007，14，30： | 1 |
| 12 | Some simple modules for the restricted Cartan-type Lie algebras 显示文摘 | Holmes R R Zhang C W | 2002 | J Pure Appl Algebra2002，173，13： | 1 |
| 13 | Effect of stress on gas permeability in concrete 显示文摘 | Sugiyama T Bremner T W Holm T A | 1996 | ACI Materials Journal1996，93，5： | 1 |
| 14 | Use of surfactant to reduce CO2 mobility in oil displacement 显示文摘 | Bernard G C Holm L W Harvey C P | 1980 | Soc Pet Engrs J1980，20，4： | 1 |
| 15 | Electrotonic length estimates in neurons with dendritic tapering or somatic shun显示文摘 | Holmes WR Rall W | 1992 | J Neurophysiol1992，68，： | 1 |
| 16 | Periodically forced linear oscillator with impacts: chaos and long-period motions 显示文摘 | Shaw S W Holmes P J | 1989 | Physical Review Letters1989，51，8： | 1 |
| 17 | The quantity and quality of physiealaetivity among those trying to lose weight 显示文摘 | Gordon P M Heath G W Holmes A | 2000 | American Journal of Preventive Medicine2000，18，1： | 1 |
| 18 | The mechanism of gas and liquid flow through porous media in the presence of foam显示文摘 | | 1968 | Journal of Petroleum Technology1968，，12： | 1 |
| 19 | Application of the generalized Pareto distribution to extreme value analysis in wind engineering显示文摘 | HOLMES J MORIARY W | 1999 | Journal of Wind Engineering and Industrial Aerodynamics1999，83，123： | 1 |
| 20 | Effect of collector,pH and ionic strength on the cationic flotation of kaolinite显示文摘 | MA X BRUCKARD W J HOLMES R | 2009 | International Journal of Mineral Processing2009，93，1： | 1 |
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