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| 1 | METAMORPHIC MECHANISMSAND THEIR CONFIGURATION MODELS显示文摘The concept of metamorphic mechanisms is presented, configuration models and configuration transformations relating to a set of new matrix operations are discussed and proposed. The configuration of a metamorphic mechanism reflects the connectivity change in the mechanism during motions which results in mobility change and presents the characteristics of the mechanism which is discussed in various applications particularly in decorative artifacts. The characteristics is further investigated with mobility analysis. | Dai Jiansheng (Department of Mechanical Engineering, School of Physical Sciences and Engineering, King’s College, University of London,Strand,London WC2R 2LS, United kingdom) Zhang Qixian (Robotics Research Institute,Beijing University of Aeronautics and | 2000 | Chinese Journal of Mechanical Engineering2000,13,3: | 61 |
| 2 | Crank conditions and rotatability of 3-RRR planar parallel mechanisms显示文摘This paper investigates the rotatability of planar parallel mechanisms by revealing the crank conditions that relate to link parameters.The paper extends the theorem of assemblability and the rotatability criterion and applies these criteria to parallel mechanisms in investigating the crank conditions of a parallel mechanism,leading to classification of three types of crank existing conditions including three-crank’s,six-crank’s and nine-crank’s of 3-RRR planar parallel mechanisms.The results are summarized as constraint conditions in relation with link parameters with a concluding table and case studies. | LI RuiQin 1 &DAI Jian S 2 1 College of Mechanical Engineering and Automation,North University of China,Taiyuan 030051,China 2 Department of Mechanical Engineering,King’s College London,University of London,WC2R 2LS,UK | 2009 | Science China(Technological Sciences)2009,52,12: | 12 |
| 3 | 吡非尼酮治疗特发性肺纤维化患者的最新3期临床试验的结果显示文摘背景:迄今已进行了3项关于吡非尼酮治疗特发性肺纤维化(IPF)患者的有效性及安全性评价的3期临床试验,其中两项临床试验表明吡非尼酮能延缓IPF患者的疾病进展(以FVC或肺活量的变化来衡量),但另一项试验结果却并未能体现上述情况。 | King TE Bradford WZ Castro-Bernardini S 李珊 黄慧 | 2014 | 中华结核和呼吸杂志2014,37,8: | 2 |
| 4 | Orientation angle rotatability of planar serial n-link manipulators显示文摘This paper presents a new method of analyzing the orientation angle rotatability of a planar serial n-link manipulator by examining the rotatability of its virtual equivalent mechanism.Workspace orientation boundary region decomposition is proposed based on the polynomial discriminant derived from a serial three-link manipulator.Orientation angle workspace indicates a set of angle ranges by which the end-effector can reach with certain orientation for every point in the reachable position workspace.By introducing a virtual equivalent mechanism,the open-chain kinematic problem is converted into a close-chain mechanism,and the Grashof-type condition is used to examine the rotatability of the end-effector link.The reachable position workspace can be divided into several Grashof intervals and non-Grashof intervals based on the extreme positions and singular configurations of a manipulator.The derived equations in this paper can be used to calculate the variation rule of the orientation angle workspace of any given planar serial n-link manipulator on the basis of its link parameters.The orientation angle rotatability of a seven-link serial manipulator is solved by the proposed method and graphical representations of the orientation angle workspaces are mapped onto a three-dimensional coordinate system.The theoretical approach has practical significance for the design of a highly dexterous serial n-link manipulator with proposed link relations. | LI RuiQin1,XIAO DengHong1 & DAI Jian S2 1 College of Mechanical Engineering and Automation,North University of China,Taiyuan 030051,China 2 Department of Mechanical Engineering,King’s College London,University of London,London WC2R 2LS,UK | 2010 | Science China(Technological Sciences)2010,53,6: | 2 |
| 5 | Taxol inhibits stretch-induced electrophysiological alterations in isolated rat hearts with acute myocardial infarction显示文摘Mechanosensitive channels have been determined to work as transducers of mechanoelectric feedback in the heart, which is associated with the generation of arrhythmias. Recent studies have investigated the role of the cytoskeleton in ion channels control. This study explored the ability of taxol to inhibit stretch-induced electrophysiological alterations in the ischemic myocardium. Thirty-two Wistar rats were randomly divided into four groups: normal control group (n=9), taxol group (n=7), myocardial infarction (MI) group (n=9), and MI+taxol group (n=7). After Langendorff perfusion, the isolated hearts were stretched for 5 s by balloon inflation to 0.2 or 0.3 mL. The effects of stretching on 90% monophasic action potential duration (MAPD90), premature ventricular beats (PVB), and ventricular tachycardia (VT) were observed for 30 s. Stretching increased MAPD90 in both the normal control and MI groups, but MAPD90 increased more in the MI group for the same degree of stretch. Taxol (5 μmol L?1) had no effect on MAPD90 under baseline, unstretched conditions, but MAPD90 in the taxol group was slightly increased after stretching compared with the normal control group (P>0.05). However, taxol reduced MAPD90 in infarcted myocardium (P<0.05 at V=0.3 mL). The incidences of PVB and VT in the MI group were higher than in the normal control group (both P<0.01). Taxol had no effect on the occurrence of arrhythmias in normal myocardium, but it inhibited PVB and VT in infarcted hearts (both P<0.01). Thus changes in MAPD and the occurrence of arrhythmias caused by mechanical stretching of the myocardium could be inhibited by taxol in isolated rat hearts during AMI, indicating the involvement of tubulin in mechanoelectric feedback in AMI. | CAO JunXian1, FU Lu1, SUN DianJun2, XIE RongSheng1, ZHOU Jue3 & QU Fan4 1Department of Cardiology, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China 2Chinese Research Center for Endemic Disease Control, Key Laboratory of Etiological Epidemiology, Ministry of Health (23618504), Harbin Medical University, Harbin 150081, China 3Pharmacy Department, King’s College London, Franklin-Wilkins Building, 150 Stamford Street, London, UK 4The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China | 2010 | Science China(Life Sciences)2010,53,8: | 2 |
| 6 | Stability of fruit quality traits in diverse watermelon cultivars tested in multiple environments显示文摘Lycopene is a naturally occurring red carotenoid compound that is found in watermelon.Lycopene has antioxidant properties.Lycopene content,sugar content and hollowheart resistance are subject to significant genotype×environment interaction(G×E),which makes breeding for these fruit quality traits difficult.The objectives of this study were to(i)evaluate the influence of years and locations on lycopene content,sugar content and hollowheart resistance for a set of watermelon genotypes,and(ii)identify genotypes with high stability for lycopene,sugar,and hollowheart resistance.A diverse set of 40 genotypes was tested over 3 years and 8 locations across the southern United States in replicated,multi-harvest trials.Lycopene was tested in a subset of 10 genotypes.Data were analyzed using univariate and multivariate stability statistics(BLUP-GGE biplot)using SASGxE and RGxE programs.There were strong effects of environment as well as G×E interaction on watermelon quality traits.On the basis of stability measures,genotypes were classified as stable or unstable for each quality trait.'Crimson Sweet'is an inbred line with high quality trait performance as well as trait stability.'Stone Mountain','Tom Watson','Crimson Sweet'and'Minilee'were among the best genotypes for lycopene content,sugar content and hollowheart resistance.We developed a stability chart based on marketable yield and average ranking generated from different stability measures for yield attributes and quality traits.The chart will assist in choosing parents for improvement of watermelon cultivars.See http://cuke.hort.ncsu.edu/cucurbit/wmelon/wmelonmain.html. | Mahendra Dia Todd C Wehner Penelope Perkins-Veazie Richard Hassell Daniel S Price George E Boyhan Stephen M Olson Stephen R King Angela R Davis Gregory E Tolla Jerome Bernier Benito Juarez | 2016 | Horticulture Research2016,3,1: | 2 |
| 7 | Idiopathic pulmonary fibrosis显示文摘 | Talmadge E King Annie Pardo Moisés Selman | 2011 | The Lancet . 2011 (9807)2011,,: | 2 |
| 8 | Flight Control Actuation Technology for Next--Generation All-- Electric Aircraft显示文摘 | Botten S L Whitley C R King A D | 2000 | Technology Review Journal-- Millennium Issue2000,,3: | 1 |
| 9 | Photoperiodic induction and inheritance of diapause in Pionea forficalis ( Lepidoptera: Pyralidae) 显示文摘 | King A B S | 1974 | Entomol Exp Appl1974,17,: | 1 |
| 10 | Integration between Business Planning and Information Systems Planning:Validating a Stage Hypothesis 显示文摘 | King W R Teo T S H | 1997 | Decision Sciences1997,28,2: | 1 |
| 11 | Surface expression of HLA-C antigen by human extravillous trophoblast 显示文摘 | King A TD Burrows SE Hiby S | 2000 | Placenta2000,21,: | 1 |
| 12 | Invasive aspergillus infections in a pedia~tric hospital: a ten-year review显示文摘 | Devi S King S | 1993 | Pediatr Infect Dis J1993,12,: | 1 |
| 13 | Local-scale fluxes of carbon dioxide in urban, environments : methodological challenges and results from Chicago 显示文摘 | Gtimmond C S B King T S Cropley F D | 2002 | Environ Poll2002,116,: | 1 |
| 14 | On edge detection of X -ray images using fuzzy sets显示文摘 | PAL S K KING R A | 1983 | IEEE Trans Part Analand Machine Intell1983,5,1: | 1 |
| 15 | Zinc biosorption on Tectona grandis L leaves biomass:Equilibrium and kinetic studies显示文摘 | Kumar Y P King P Prasad V S R K | 2006 | Chemical Engineering Journal2006,124,1: | 1 |
| 16 | Connexins as targets for cancer chemopmvention and chemotherapy显示文摘 | KING T J BERTRAM J S | 2005 | Biochim Biophys Acta2005,1719,12: | 1 |
| 17 | A 27 Kda heat shock protein that has anomalous prognostic powers in early and advanced breast cancer 显示文摘 | Love S King RJ | 1994 | Br J Cancer1994,69,4: | 1 |
| 18 | Theoretical Modeling of Tm-doped Silica Fibre Lasers显示文摘 | Jackson S D King T A | 2003 | Journal of Lightwave Technology2003,17,5: | 1 |
| 19 | Transplantation of olfactory ensheathing cells fails to promote significant axonal regeneration from dorsal roots into the rat cervical cord 显示文摘 | Gomez VM Averill S King V | 2003 | J Neurocytol2003,32,1: | 1 |
| 20 | The growth of geological structures by repeated earthquakes,1,Conceptual framework显示文摘 | king G C Stein R S Rundle J B | 1988 | Journal of Geophysical Research1988,93,13: | 1 |