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| 1 | Mesenchymal stem cell therapy in patients with small bowel transplantation:Single center experience显示文摘AIM:To study the effects of mesenchymal stem cell(MSC) therapy on the prevention of acute rejection and graft vs host disease following small bowel transplantation.METHODS: In our transplantation center, 6 isolated intestinal transplants have been performed with MSC therapy since 2009. The primary reasons for transplants were short gut syndrome caused by surgical intestine resection for superior mesenteric artery thrombosis(n = 4), Crohn's disease(n = 1) and intestinal aganglionosis(n = 1). Two of the patients were children. At the time of reperfusion, the first dose of MSCs cultured from the patient's bone marrow was passedinto the transplanted intestinal artery at a dose of 1000000 cells/kg. The second and third doses of MSCs were given directly into the mesenteric artery through the arterial anastomosis using an angiography catheter on day 15 and 30 post-transplant.RESULTS: The median follow-up for these patients was 10.6 mo(min: 2 mo-max: 30 mo). Three of the patients developed severe acute rejection. One of these patients did not respond to bolus steroid therapy. Although the other two patients did respond to antirejection treatment, they developed severe fungal and bacterial infections. All of these patients died in the 2nd and 3rd months post-transplant due to sepsis. The remaining patients who did not have acute rejection had good quality of life with no complications observed during the follow-up period. In addition, their intestinal grafts were functioning properly in the 13th, 25th and 30th month post-transplant. The patients who survived did not encounter any problems related to MSC transplantation.CONCLUSION: Although this is a small case series and not a randomized study, it is our opinion that small bowel transplantation is an effective treatment for intestinal failure, and MSC therapy may help to prevent acute rejection and graft vs host disease following intestinal transplantation. | Sait Murat Do?an Sel?uk K?l?n? Eyüp Kebap?? Cem Tu?men Mustafa ?lmez Cezmi Karaca Alp Gürkan Ma?allah Baran Yusuf Kurtulmu? | 2014 | World Journal of Gastroenterology2014，20，25： | 3 |
| 2 | Stenotrophomonas maltophlia:antimiceobial resistance and molecular typing of an emerging pathogen in a Turkish university hospital显示文摘 | Gülmez D Hascelik G | 2005 | Clin Microbiol Infect2005，11，11： | 1 |
| 3 | Resistance to fracture of endodontically trea-ted teeth restored with different post systems显示文摘 | Akkayan B Gülmez T | 2002 | J Prosthet Dent2002，87，4： | 1 |
| 4 | Stenotrophomonas maltophilia: antimicrobial resistance and molecular typing of an emerging pathogen in a Turkish university hospital显示文摘 | D.Gülmez G.Has?elik | 2005 | Clinical Microbiology and Infection2005，，11： | 1 |
| 5 | Resistance to fracture of endodonticallytreated teeth restored with different post systems显示文摘 | Akkayan B Gülmez T | 2002 | J ProsthetDent2002，87，4： | 1 |
| 6 | Resistance to fracture of endodontically treated teeth restored with different post systems 显示文摘 | Akkayan B GU lmez T | 2002 | J Prost het Dent2002，87，4： | 1 |
| 7 | Tissue segmentation in ultrasound images by using genetic algorithms显示文摘 | DOKUR Z LMEZ T | 2008 | Expert SystAppl2008，34，4： | 1 |
| 8 | Clinical significance of serum transforming growth facto:beta 1 (TGF-βI) levels in patients with epithelial ovarian cancer显示文摘 | Tas F Karabulut S Ser | 2014 | Tumour Biol2014，35，4： | 1 |
| 9 | Carbapenem-resistant Escherichia coli and Klebsiella pneumoniae isolates from Turkey with OXA-48-1ike carbapenemases and outer membrane protein loss显示文摘 | Gülmez D Woodford N Palepou MF | | 0，，06： | 1 |
| 10 | Carbapenem-resistantEsche-richia coliandKlebsiella pneumoniaeisolates from Turkey withOXA-48-like carbapenemases and outer membrane protein loss显示文摘 | Gülmez D Woodford N Palepou MF | 2008 | Int J Antimicrob Agents2008，31，6： | 1 |
| 11 | ECG beat classification by a novel hybrid neural network显示文摘 | Dokur Z (O)lmez T | 2001 | Computer Methods and Program in Biomedicine2001，66，23： | 1 |
| 12 | Resistance to fracture of endodontically treated teeth restored with different post systems显示文摘 | Akkayan B G(u)lmez T | | 0，，04： | 1 |
| 13 | Optimization of ozone treatment of fresh-cut green leaf lettuce显示文摘 | LMEZ H AKBAS M Y | 2009 | J Food Eng2009，90，4： | 1 |
| 14 | Potential alternative disinfection methods for organic fresh-cut industry for minimizing water consumption and environmental impact显示文摘 | Hülya ?lmez Ursula Kretzschmar | 2008 | LWT - Food Science and Technology2008，，3： | 1 |
| 15 | The local antinociceptive actions of nonsteroidal antiinflammatory drugs in the mouse radiant heat tail-flick test显示文摘 | Dogrul A Gülmez SE Deveci MS | 2007 | Anesth Analg2007，104，4： | 1 |
| 16 | Potential alternative disinfection methods for organic fresh-cut industry for minimizing water consumption and environmental impact显示文摘 | (O)lmez H Kretzschmar U | | 0，，03： | 1 |
| 17 | Serum vascular endothelial growth factor receptor-2 and adropin levels in age-related macular degeneration显示文摘AIM: To investigate the serum levels of vascular endothelial growth factor receptor-2(VEGFR-2) and adropin in age-related macular degeneration(AMD)patients.·METHODS: Ninety-eight AMD patients were included in the study. Seventy-eight age- and sex-matched healthy volunteers were recruited as the control group.Fundus florescein angiography and optical coherence tomography were performed to assess the posterior segment details. Serum VEGFR-2 and adropin levels were measured using enzyme-linked immunosorbent assays and compared between the study groups.· RESULTS: AMD group had significantly increased foveal retinal thickness, serum LDL and HDL levels and significantly decreased subfoveal choroidal thickness(P =0.01, 0.047, 0.025 and <0.001, respectively). Serum VEGFR-2level revealed a significant decrease in AMD patients compared to controls(26.48 ±6.44 vs 30.42 ±7.92 ng/m L,P <0.001). There was an insignificant increase in serum adropin level in AMD patients(6.17±3.19 vs 5.79±2.71 ng/m L,P =0.4). Serum level of VEGFR-2 in AMD patients had a significant negative correlation with foveal retinal thickness(r =-0.226, P =0.025) and a significant positive correlation with subfoveal choroidal thickness(r=0.2, P=0.048).·CONCLUSION: The current study demonstrated that the decreased serum VEGFR-2 level may be considered in the development of AMD. Adropin does not seem to play a role in the pathogenesis of AMD. | Nurgül rnek Kemal rnek Süleyman Aydin Musa Yilmaz Yasar lmez | 2016 | International Journal of Ophthalmology(English edition)2016，9，4： | 1 |
| 18 | Resistance to fracture of endodonticallytreated teeth restored with different post systems显示文摘 | AKKAYAN B GüLMEZ T | 2002 | ProsthetDent2002，87，4： | 1 |
| 19 | Resistance to fracture of endodontically treated teeth restored with different post systems显示文摘 | Akkayan B G u lmez T | 2002 | J Prosthet Dent2002，87，4： | 1 |
| 20 | Resistance to fracture of endodontically treated teeth restored with different post systems显示文摘 | Akkayan B Gülmez T | | 0，，04： | 1 |
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