|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 人类血压测量方法:美国心脏协会科学声明显示文摘准确的血压测量对高血压诊断与治疗至关重要。该文是美国心脏协会关于人类血压测量的最新科学声明。业已证实,在诊室许多电子血压计可以准确测量血压,同时减少与听诊法有关的人为误差。即使没有一个观察者在场,全自动电子血压计也可以通过多次测量提供较听诊法更准确的血压测量值。研究表明诊室外所测血压与诊室血压比较存在实质性差别。目前认为动态血压监测是诊室外血压评估的参考标准,当动态血压监测不可行或患者不能耐受时,家庭血压监测则是一个替代方法。 | 赵狄(摘译) 练桂丽(审校) Muntner P Shimbo D Carey RM Charleston JB Gaillard T Misra S Myers MG Ogedegbe G Schwartz JE Townsend RR Urbina EM Viera AJ White WB Wright JT Jr | 2019 | 中华高血压杂志2019，27，6： | 16 |
| 2 | 肥胖和动脉老化:Whitehall Ⅱ队列主动脉僵硬度纵向研究显示文摘该研究旨在确定肥胖症是否中年后动脉硬化加速的独立预测因子。纳入Whitehall Ⅱ研究受试者男性3789例,女性1383例,平均年龄66岁,均接受颈-股动脉压检测,4年后再次进行测定。一般肥胖状况由体质量指数,中心肥胖由腰围和腰臀比,脂肪含量百分比由身体阻抗来评估。通过线性混合模型,对年龄、性别、种族和平均动脉压进行调整后,所有肥胖症测量指标与主动脉硬化[通过随访的脉搏波传导速度(pulse wave velocity,PWV)较基线增加值来确定]相关。 | 刘莉 叶鹏 Brunner EJ Shipley MJ Ahmadi-Abhari S Tabak AG McEniery CM Wilkinson IB Marmot MG Singh-Manoux A Kivimaki M | 2015 | 中华高血压杂志2015，23，6： | 8 |
| 3 | 具有低动脉粥样硬化风险特征的专业耐力运动员的亚临床冠状动脉疾病发病率显示文摘研究表明,具有冠状动脉疾病(coronary artery disease,CAD)危险因素的中老年(健将)运动员比久坐个体冠状动脉钙化(coronary artery calcium,CAC)评分更高。尚没有研究评估具有低动脉粥样硬化风险特征的专业运动员的CAD患病率。 | 刘莉 叶鹏 Merghani A Maestrini V Rosmini S Cox AT Dhutia H Bastiaenen R David S Yeo TJ Narain R Malhotra A Papadakis M Wilson MG Tome M AlFakih K Moon JC Sharma S | 2017 | 中华高血压杂志2017，25，6： | 8 |
| 4 | 急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI. | Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS | 2017 | 中华神经外科疾病研究杂志2017，16，6： | 8 |
| 5 | Differentiation of T regulatory cells by immature dendritic cells.显示文摘 | Roncarolo MG Bacchetta RC Bordignon S | | 0，，： | 2 |
| 6 | Cognitive disorder and dementia in type 2 diabetes mellitus显示文摘Insulin,a key pleiotropic hormone,regulates metabolism through several signaling pathways in target tissues including skeletal muscle,liver,and brain.In the brain,insulin modulates learning and memory,and impaired insulin signaling is associated with metabolic dysregulation and neurodegenerative diseases.At the receptor level,in aging and Alzheimer’s disease(AD)models,the amount of insulin receptors and their functions are decreased.Clinical and animal model studies suggest that memory improvements are due to changes in insulin levels.Furthermore,diabetes mellitus(DM)and insulin resistance are associated with age-related cognitive decline,increased levels ofβ-amyloid peptide,phosphorylation of tau protein;oxidative stress,pro-inflammatory cytokine production and dyslipidemia. Recent evidence shows that deleting brain insulin receptors leads to mildobesity and insulin resistance without influencing brain size and apoptosis development.Conversely, deleting insulin-like growth factor 1 receptor (IGF-1R) affects brain size anddevelopment, and contributes to behavior changes. Insulin is synthesized locally in the brain andis released from the neurons. Here, we reviewed proposed pathophysiological hypotheses toexplain increased risk of dementia in the presence of DM. Regardless of the exact sequence ofevents leading to neurodegeneration, there is strong evidence that mitochondrial dysfunctionplays a key role in AD and DM. A triple transgenic mouse model of AD showed mitochondrialdysfunction, oxidative stress, and loss of synaptic integrity. These alterations are comparable tothose induced in wild-type mice treated with sucrose, which is consistent with the proposal thatmitochondrial alterations are associated with DM and contribute to AD development. Alterationsin insulin/IGF-1 signaling in DM could lead to mitochondrial dysfunction and low antioxidantcapacity of the cell. Thus, insulin/IGF-1 signaling is important for increased neural processing andsystemic metabolism, and could be a specific target for therapeutic strategies to decreasealterations associated with age-related cognitive decline. | Genaro G Ortiz Miguel Huerta Héctor A González-Usigli Erandis D Torres-Sánchez Daniela LC Delgado-Lara Fermín P Pacheco-Moisés Mario A Mireles-Ramírez Blanca MG Torres-Mendoza Roxana I Moreno-Cih Irma E Velázquez-Brizuela | 2022 | World Journal of Diabetes2022，13，4： | 2 |
| 7 | 妊娠期基因-环境相互作用与母体砷甲基化效率显示文摘单核昔酸多态性(SNPs)主要是指在基因组水平上由单个核昔酸的变异所引起的DNA序列多态性,是人类可遗传的变异中最常见的一种,占所有已知多态性的80%以上。有研究表明,SNPs可能通过影响砷的甲基化效干扰砷代谢。而环境与基因的交互作用是否会影响孕期砷代谢目前尚不明确,因此,本研究分析SNP-砷的交互作用对砷甲基化效率的影响。 | Gao S Mostofa MG Quamruzzaman Q 李园园(编译) | 2019 | 中华预防医学杂志2019，53，5： | 2 |
| 8 | Effects of VHL deficiency on endolymphatic duct and sac 显示文摘 | GI sker S Lonser RR Tran MG | 2005 | Cancer Res2005，65，10： | 1 |
| 9 | Apo B gene polymorphisms and coronary artery disease: a meta-analysis 显示文摘 | Chiodini BD Barlera S Franzosi MG | 2003 | Atherosclerosis2003，167，2： | 1 |
| 10 | Laparoscopic adrenalectomy for large-Volume( ≥5 cm ) adrenal masses 显示文摘 | Hobart MG Gilli S Sehweizer D | 2000 | J Endour2000，14，2： | 1 |
| 11 | Resis-tantStarch-A Review显示文摘 | Sajilata MG Rekha S Singhal Pushpa R Kuikami | 2006 | Comprehensive Reviews in Food Science and Food Safety2006，5，： | 1 |
| 12 | Development of monocytes, macrophages, and dendritic cells 显示文摘 | Geissmann F Manz MG Jung S | 2010 | Sci2010，327，5966： | 1 |
| 13 | Cyclic AMP elevation is sufficient to promote the survival of spinal motor neurons in vitro显示文摘 | Hanson MG Shen S Barres BA | 1998 | The Journal of Neuroscience1998，18，18： | 1 |
| 14 | SDF-1 involvement in endothelial phenotype and ischemia-induced recruitment of bone marrow progenitor cells显示文摘 | De Falco E Porcelli D Torella AR Straino S Iachininoto MG Orlandi A | 2004 | Blood2004，104，12： | 1 |
| 15 | Combined transmandibular-zygomatic approach and infratemporal craniotomy for intracrnial skull base tumors 显示文摘 | Donovan MG Ondra S Illig JJ | 1993 | J Oral Maxillofac Surg1993，51，： | 1 |
| 16 | Inhibitors of HIV-1 replication that inhibit HIV integrase显示文摘 | Robinson WE Reinecke MG Abdel-Malek S | 1996 | Proc Natl Acad Sci USA1996，93，13： | 1 |
| 17 | Antibodies to bovine beta- casein in diabetes and other autoimmune diseases 显示文摘 | Monetini L Cavallo MG Manfrini S | 2002 | Horm Metab Res2002，34，： | 1 |
| 18 | Health inequalities among British civil servants : the Whitehall II study 显示文摘 | Marmot MG Smith GD Stansfeld S | 1991 | Lancet1991，337，： | 1 |
| 19 | Specific targeting of HER2 overexpressing breast cancer cells with doxorubicin-loaded trastuzumab-modified human serum albumin nanopartieles 显示文摘 | Anlaom MG Wagner S Kreuter J | 2008 | Bioeonjug Chem2008，19，12： | 1 |
| 20 | Epithelial- to- mesenchymal plasticity harnesses endocytic circuitries 显示文摘 | Corallino S Malabarba MG Zobel M | 2015 | Front Oncol2015，5，45： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员