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| 1 | High-flow nasal oxygen availability for sedation decreases the use of general anesthesia during endoscopic retrograde cholangiopancreatography and endoscopic ultrasound显示文摘AIM To examine whether high-flow nasal oxygen(HFNO) availability influences the use of general anesthesia(GA) in patients undergoing endoscopic retrograde cholangiopancreatography(ERCP) and endoscopic ultrasound(EUS) and associated outcomes.METHODS In this retrospective study, patients were stratified into 3 eras between October 1, 2013 and June 30, 2014 based on HFNO availability for deep sedation at the time of their endoscopy. During the first and last 3-mo eras(era 1 and 3), no HFNO was available, whereas it was an option during the second 3-mo era(era 2). The primary outcome was the percent utilization of GA vs deep sedation in each period. Secondary outcomes included oxygen saturation nadir during sedation between periods, as well as procedure duration, and anesthesia-only time between periods and for GA vs sedation cases respectively.RESULTS During the study period 238 ERCP or EUS cases were identified for analysis. Statistical testing was employed and a P < 0.050 was significant unless the Bonferroni correction for multiple comparisons was used. General anesthesia use was significantly lower in era 2 compared to era 1 with the same trend between era 2 and 3(P = 0.012 and 0.045 respectively). The oxygen saturation nadir during sedation was significantly higher in era 2 compared to era 3(P < 0.001) but not between eras 1 and 2(P = 0.028) or 1 and 3(P = 0.069). The procedure time within each era was significantly longer under GA compared to deep sedation(P ≤ 0.007) as was the anesthesia-only time(P ≤ 0.001).CONCLUSION High-flow nasal oxygen availability was associated with decreased GA utilization and improved oxygenation for ERCP and EUS during sedation. | Roman Schumann Nikola S Natov Klifford A Rocuts-Martinez Matthew D Finkelman Tom V Phan Sanjay R Hegde Robert M Knapp | 2016 | World Journal of Gastroenterology2016，22，47： | 9 |
| 2 | Trueness verification and traceability assessment of results from commercial systems for t of six enzyme activities in serum:An international study in the EC4 framework of the calibration 2000 project 显示文摘 | Jansen R Schumann G Baadenhuijsen H | 2006 | Clin Chim Acta2006，368，12： | 1 |
| 3 | Mapping of quantitative trait loci determining agronomic important characters in hexaploid wheat (Triticum aestivum L.)显示文摘 | A. B?rner E. Schumann A. Fürste H. C?ster B. Leithold M. R?der W. Weber | 2002 | Theoretical and Applied Genetics (-)2002，，6： | 1 |
| 4 | Homogeneously catalyzed epoxidation of α,β-unsaturated ketones using simple aluminum salts and aqueous H202- Is it possible? 显示文摘 | RINALDI R DE OLIVEIRA H F N SCHUMANN H | 2009 | J Mol Catal A: Chem2009，307，12： | 1 |
| 5 | Detection of two variants of complement component C3 in C3-deficient guinea pigs distinguished by the absence and presence of a thiolester 显示文摘 | LAMPING N SCHUMANN R R BURGER R | 2000 | Mol Immunol2000，37，： | 1 |
| 6 | Postoperative hyperglycemia:Clinical bebefits of insulin therapy显示文摘 | SCHUMANN D R N F AAN | 1990 | Heart Lung1990，19，： | 1 |
| 7 | Orientational behavior of thermotropic liquid crystals on surfaces presenting electrostatically bound vesicu-stomatitis virus显示文摘 | Espinoza L A T Schumann R K Luk Y Y | 2004 | Langmuir2004，20，6： | 1 |
| 8 | Central and Peripheral Routes to Advertising Effectiveness: The Moderating Role of Involvement显示文摘 | PETTY R E CACIOPPO J T SCHUMANN D | 1983 | Journal of Consumer Research1983，10，2： | 1 |
| 9 | On-Line Separation of Short-Lived Tungsten Isotopes From Tantalum, Hafnium and Lutetium by Adsorption on Ion Exchangers From Aqueous Ammonia Solution显示文摘 | Schumann D Dressler R Taut S | 1996 | J Radioanal Nucl Chem Lett1996，214，1： | 1 |
| 10 | Potential role of tissue transglutaminase in glaucoma filtering surgery 显示文摘 | Priglinger SG Alge CS Kook D Thiel M Schumann R Eibl K | 2005 | Invest Ophthalmol Vis Sci2005，47，9： | 1 |
| 11 | Optimal Control of an Active An&oil Suspension for an Off-road Utility Vehicle Using Interconnected Hydra Gas Suspension Units 显示文摘 | Schumann A R Anderson R J | 2003 | Vehicle System Dynamics2003，37，2： | 1 |
| 12 | Tumor necrosis factor alpha (TNF-a)is cardiodepressant in pathophysiologically relevant concentrations without inducing induciblr nitric oxide-(No)-synthase (iNos)or triggering serious cytotoxicity 显示文摘 | Schumann H Fuchs R | 1997 | J Mol cell cardiol1997，29，： | 1 |
| 13 | Association of the toll-like receptor 2 A-16934T promoter polymorphism with severe atopie dermatitis 显示文摘 | Oh D Y Schumann R R Hamann L | 2009 | Allergy2009，64，11： | 1 |
| 14 | Intraoperative management of patients with incidental cateeholamine producing tumors: a literature review and a-nalysis 显示文摘 | Hariskov S Schumann R | 2013 | Journal of anaesthesiology clinical pharmacology2013，29，1： | 1 |
| 15 | High temperature stress measurements during the oxidation of NiAI显示文摘 | SCHUMANN E SARIOGLU C BLACHEREJ R et ai | 2000 | Oxidation of Metals2000，53，： | 1 |
| 16 | Function of lipopolysaccharide (LPS)- binding protein (LBP) and CD14, the receptor for LPS! LBP complexes: a short review 显示文摘 | Schumann R R | 1992 | Res Immunol1992，143，1： | 1 |
| 17 | IFCC prima- ry reference procedures for the Measurement of catalytic activity concentrations of enzymes at 37℃ 显示文摘 | Schumann G Aoki R Ferrero CA | 2006 | Clin Chem Lab Med2006，44，9： | 1 |
| 18 | Evalua- tion of the internal limiting membrane after conventional peeling during macular hole surgery 显示文摘 | Haritoglou C Schumann R Reiniger I | 2006 | Retina2006，26，： | 1 |
| 19 | Alcohol consumption and the body's biological cloek显示文摘 | Spanagel R Rosenwasser A M Schumann G | 2005 | Alcohol Clin Exp Res2005，29，8： | 1 |
| 20 | Acute peripheral arteri al occlusive disease 显示文摘 | Schumann R Rieger J Ludwig M | 2007 | Med Klin (Munich)2007，102，6： | 1 |
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