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| 1 | 远程缺血预处理对高危心脏手术患者肾功能的长期影响:肾脏RIP试验的随访结果显示文摘在一项多中心随机试验中,德国学者将急性肾损伤高风险患者纳入研究对象。来自4家医院的240例患者,被随机分配到远程缺血预处理组或对照组;结果发现,远程缺血预处理减少了心脏手术高危患者的急性肾损伤。本文中,作者又报告了远程缺血预处理对90 d结局的影响。在这项肾脏RIP试验的随访研究中, | Zarbock A Kellum JA Van Aken H 王建中 | 2017 | 中华肾病研究电子杂志2017，6，4： | 9 |
| 2 | Assessment of oxidative stress in chronic pancreatitis patients显示文摘AIM: To assess the levels of antioxidant capacity and oxidative damage in blood of chronic pancreatitis (CP) patients in comparison with those in healthy control sub- jects, by using several different analytical techniques. METHODS: Thirty-five CP patients and 35 healthy con- trol subjects were investigated prospectively with re- spect to plasma levels of thiols, ferric reducing ability of plasma (FRAP, i.e. antioxidant capacity), levels of protein carbonyls and thiobarbituric acid reactive substances (TBARS). Additionally, we evaluated the production of reactive oxygen species (ROS) in whole blood. RESULTS: The antioxidative thiols including cysteine, cysteinylglycine and glutathione were significantly lower in CP patients. In addition, the non-enzymatic antioxi- dant capacity was significantly lower in CP patients, which correlated with the amount of oxidative protein (protein carbonyls) and the extent of lipid damage (TBARS), both were significantly higher in CP patients. The ROS production in whole blood after stimulation with phorbol 12-myritate 13-acetaat, demonstrated a strong tendency to produce more ROS in CP patients. CONCLUSION: Oxidative stress may contribute to the pathogenesis of chronic pancreatitis by decreasing anti- oxidant capacity and increasing oxidative damage in CP patients may be a rationale for intervention with antioxi- dant therapy. | Mariette Verlaan Hennie MJ Roelofs Annie van Schaik Geert JA Wanten Jan BMJ Jansen Wilbert HM Peters Joost PH Drenth | 2006 | World Journal of Gastroenterology2006，12，35： | 3 |
| 3 | Total elbow arthroplasty is moving forward: Review on past, present and future显示文摘The elbow joint is a complex joint, which, when impaired in function, leads to severe disability. In some cases however, an arthroplasty might be an appropriate treatment. In the past four decades, large steps havebeen taken to optimize this treatment in order to achieve better post-operative outcomes. To understand these progresses and to discover aspects for upcoming improvements, we present a review on the past developments, the present state of affairs and future developments which may improve patient care further. | Ante Prki? Christiaan JA van Bergen Bertram The Denise Eygendaal | 2016 | World Journal of Orthopedics2016，7，1： | 3 |
| 4 | Diagnosing, planning and evaluating osteochondral ankle defects with imaging modalities显示文摘This current concepts review outlines the role of diffe-rent imaging modalities in the diagnosis, preoperative planning, and follow-up of osteochondral ankle defects. An osteochondral ankle defect involves the articular cartilage and subchondral bone(usually of the talus) and is mostly caused by an ankle supination trauma. Conventional radiographs are useful as an initial imaging tool in the diagnostic process, but have only moderate sensitivity for the detection of osteochondral defects. Computed tomography(CT) and magnetic resonance imaging(MRI) are more accurate imaging modalities. Recently, ultrasonography and single photon emission CT have been described for the evaluation of osteochondral talar defects. CT is the most valuable modality for assessing the exact location and size of bony lesions. Cartilage and subchondral bone damage can be visualized using MRI, but the defect size tends to be overestimated due to bone edema. CT with the ankle in full plantar flexion has been shown a reliable tool for preoperative planning of the surgical approach. Postoperative imaging is useful for objective assessment of repair tissue or degenerative changes of the ankle joint. Plain radiography, CT and MRI have been used in outcome studies, and different scoring systems are available. | Christiaan JA van Bergen Rogier M Gerards Kim TM Opdam Maaike P Terra Gino MMJ Kerkhoffs | 2015 | World Journal of Orthopedics2015，6，11： | 3 |
| 5 | 健康女性隔日给予阿司匹林预防癌症、心血管疾病和胃肠道出血风险的个体化预测显示文摘阿司匹林在癌症和心血管疾病(cardiovascular disease,CVD)一级预防中的作用仍不清楚。该研究旨在确定女性使用阿司匹林治疗是否能改善发生癌症、CVD和重大消化道出血的风险。方法:对女性健康研究(一项随机试验,隔日服用阿司匹林100mg/安慰剂的临床实验)中拥有血浆样本的健康女性27 939人进行长期随访,个体化预测使用阿司匹林是否降低合并CVD、癌症和主要消化道出血的绝对风险。 | 刘莉 叶鹏 van Kruijsdijk RC Visseren FL Ridker PM Dorresteijn JA Buring JE van der Graaf Y Cook NR | 2014 | 中华高血压杂志2014，22，12： | 2 |
| 6 | Prognostic value of receptors for insulin-like growth factor 1, somatostatin, and epidermal growth factor in human breast cancer显示文摘 | Foekens JA Portengen H van Putten WL | 1989 | Cancer Res1989，49，： | 2 |
| 7 | Developments in diagnosis and treatment of paediatric septic arthritis显示文摘Acute septic arthritis in children is an orthopaedic emergency.A delay in diagnosis and inappropriate treatment can result in devastating damage to the joint with lifelong disability as a consequence.The clinical presentation can be a diagnostic challenge,especially in young children.A recent systematic review showed that joint tenderness and fever are important signals of septic arthritis.Ultrasound is helpful in detecting the presence of a joint effusion.Plain radiographs may show bone changes but magnetic resonance imaging is the most reliable imaging study for detecting concomitant osteomyelitis.The diagnosis of acute septic arthritis is highly suggestive when pus is aspirated from the joint,in case of a positive culture or a positive gram stain of the joint fluid,or if there is a white blood-cell count in the joint fluid of more than 50000/mm3.Staphylococcus aureus is the most commonly cultured organism.Recent systematic reviews have identified the most effective drainage techniques,including needle aspiration,arthroscopy and arthrotomy,depending on the affected joint.After the drainage procedure it is important to monitor the clinical and laboratory outcomes.Additional drainage procedures may be necessary in select cases. | Cornelia M Donders Anne J Spaans Herbert van Wering Christiaan JA van Bergen | 2022 | World Journal of Orthopedics2022，13，2： | 2 |
| 8 | Carotid angioplasty and stent placement:comparison of transcranial Doppler US data and clinical outcome with and without filtering cerebral protection devices in 509 patients显示文摘 | Vos JA van den Berg JC Ernst SMPG | 2005 | Radiology2005，234，： | 1 |
| 9 | Preoperative chemotherapy in primary operable breast cancer: results from the European Organization for Research and Treatment of Cancer trial 10 902显示文摘 | van der Hage JA van de Velde CJH Julien JP | 2001 | J Clin Oncol2001，19，22： | 1 |
| 10 | Neuronal cell death in a rat model for mesial temporal lobe epilepsy is induced by the initial status epilepticus and not by later repeated spontaneous seizures显示文摘 | Gorter JA Gonealves PM Van Vliet EA | 2003 | Epilepsia2003，44，5： | 1 |
| 11 | Dose-finding study of daily GnRH antagonist for the prevention of premature Lid surges in IVF/ICSI patients:optimal changes in LH and progesterone for clinical pregnancy显示文摘 | Huime JA van Loonen AC Schats R | 2005 | Hum Reprod2005，20，2： | 1 |
| 12 | Increased urinary cystatin C reflects structural and functional renal tubular impairment independent of glomerular filtration rate 显示文摘 | Herget- Rosenthal S van Wijk JA Brcker- Preuss M | 2007 | Clin Biochem2007，40，： | 1 |
| 13 | Steroid sex hormones regulate the release of tumor necrosis factor by macrophages 显示文摘 | Van Alten PJ Greager JA | 1995 | Cell Immunol1995，160，： | 1 |
| 14 | Segregation analyses for presence of major genes affecting growth,backfat,and litter size in Dutch Meishan crossbreds显示文摘 | Van Arendonk JA Brascamp EW | 1997 | J Anim Sci1997，75，11： | 1 |
| 15 | Trends in incidence of and mortality from cancer in the Netherlands in the period 1989-1998显示文摘 | Siesling S van Dijck JA Visser O | 2003 | Eur J Cancer2003，39，17： | 1 |
| 16 | Long-term results of a randomized trial comparing breast-conserving therapy with mastectomy:European organization for research and treatment of cancer 10801 trial显示文摘 | van Dougen JA Voogd AC Fentiman IS | 2000 | J Natl Cancer Inst2000，92，14： | 1 |
| 17 | Experience with fetoscopic cord ligation 显示文摘 | Deprest jA VAn Ballaer PP Evrard VA | 1998 | Eur J Obstet Gynecol Reprod Biol1998，81，2： | 1 |
| 18 | Islet cell carcinomas of the pancreas:a twenty-years experience显示文摘 | Thompson GB van Heerden JA Grant CS | 1988 | Surgery1988，104，： | 1 |
| 19 | Bone volume after secondary bone grafting in unilateral and bilateral clefts determined by computed tomography scans显示文摘 | Van der Meij AJ Baart JA Prahl-Andersen B | 2001 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2001，92，2： | 1 |
| 20 | Effect of corticosteroid therapy on serum cystatin C and beta2-microglobulin concentrations显示文摘 | Bokenkamp A van Wijk JA Lentze M J | 2002 | Clin Chem2002，48，7： | 1 |
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