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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Yes相关蛋白通过肿瘤坏死因子受体相关因子6控制内皮活化和血管炎症显示文摘继发于异常的内皮激活的微血管炎症和内皮功能障碍在败血症和器官衰竭的病理生理学中起关键作用。抑制内皮细胞过度活化的内在信号传导机制尚未完全明了。该研究旨在确定Yes相关蛋白(Yes-associated protein,YAP)(Hippo通路的主要转录共激活剂)在调节内皮活化和血管炎症的强度和程度中的中心作用。 | 刘青 叶鹏 Lv Y Kim K Sheng Y Cho J Qain Z Zhao YY Hu G Pan D Malik AB | 2018 | 中华高血压杂志2018，26，8： | 20 |
| 3 | 代谢健康的肥胖和腹型肥胖与高血压风险增加相关显示文摘代谢健康型肥胖是指具有正常代谢特征的肥胖人群。研究者在中国农村地区队列研究(the rural Chinese cohort study)的成年人中,探究了代谢健康型肥胖与高血压风险的关系。这项前瞻性队列研究纳入中国成人9137名,在基线时(2007-2008年)无高血压、2型糖尿病或血脂异常,在2013-2014年进行随访。 | 周卫(译) 袁源(审校) Zhao Y Qin P Sun HH Liu Y Liu D Zhou Q Guo C Li Q Tian G Wu X Hu D Sun X Zhang M | 2020 | 中华高血压杂志2020，28，9： | 7 |
| 4 | An essential role for TAK1 in the contact hypersensitivity response显示文摘Contact hypersensitivity(CHS)is a delayed-type hypersensitivity that can be induced by haptens,such as 2,4-dinitrofluorobenzene(DNFB).Innate and adaptive immunities are both important for the development of CHS.To treat CHS-related diseases,such as allergic contact dermatitis,a disease prevalent in industrialized countries,ways of interfering with improper immune function during CHS responses need to be identified.Transforming growth factor-b-activated kinase-1(TAK1),a member of mitogen-activated protein kinase kinase kinase family,is important for both innate and adaptive immunities.We thus hypothesized that the CHS response could be inhibited by interfering with TAK1 activity.Using a mouse model in which TAK1 deletion can be locally induced,we observed that TAK deficiency led to an impaired CHS response and was associated with defective T-cell expansion,activation and interferon(IFN)-c production.In addition,we investigated the effect of deleting TAK1 specifically in dendritic cells(DC)on the CHS response.We found that when TAK1 is deficient in DC,the CHS response was abolished and hapten-elicited T-cell responses were defective.Collectively,this study demonstrates an essential role of TAK1 in the induction of CHS and suggests that targeting TAK1 could be a viable approach to treat CHS. | Yan G Zhao Yunqi Wang Weidong Hao Yisong Y Wan | 2011 | Cellular & Molecular Immunology2011，8，4： | 4 |
| 5 | Determination of Copper, Nickel, Cobalt, Silver, Lead, Cadmium and Mercury Ions in Water by Solid Phase Extraction and the RP-HPLC with UV-Vis Detection显示文摘 | Hu Q F Yang G Y Zhao Y Y | 2003 | Ana Bioanal Chem2003，375，78： | 2 |
| 6 | Renal dysfunction and its relative factors in metabolic syndrome显示文摘 | Jin Y H Zhu Z M Zhao Z G | 2003 | Am J Hypertens2003，16，5： | 2 |
| 7 | Rapid analysis of flavor volatiles in apple wine using headspace solid-phase microextraction 显示文摘 | Wang L Xu Y Zhao G | 2004 | Journal of the Institute of Brewing2004，110，1： | 1 |
| 8 | Modern seismic methods in engineering investigation at a nuclear power plant site显示文摘 | Zhao Y G Jin H X Wang C F | 1996 | Scientia Geologica Sinica1996，5，4： | 1 |
| 9 | Domain wall scattering explains 300% ballistic magnetoresistance of nanocontacts显示文摘 | Tatara G Zhao Y W Munoz M | 1999 | Phys Rev Lett1999，83，10： | 1 |
| 10 | Diagnostic value of CEA, CYFRA21 - 1 ,NSE and CAl25 assay in serum and pleural effusion of patients with lung cancer显示文摘 | WU G P BA J ZHAO Y J | 2007 | Acta Cytd2007，51，4： | 1 |
| 11 | Colloidal subwavelength nanostructures {or antireflection optical coatings显示文摘 | Zhao Y Wang J S Mao G Z | 2005 | Opt Lett2005，30，14： | 1 |
| 12 | Moment methods for structural reliability 显示文摘 | Zhao Y G Ono T | 2001 | Structural Safety2001，23，1： | 1 |
| 13 | Characterizations of recessed gate AlGaN/GaN HEMTs on sapphire显示文摘 | EGAWA T ZHAO G Y ISHIKAWA H | 2001 | IEEE Transactions on Electron Devices2001，48，3： | 1 |
| 14 | Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development显示文摘 | Rhee D Y Zhao X Q Huang G Y | 2009 | Development2009，136，： | 1 |
| 15 | A new integrated design method based on fuzzy matter-element optimization 显示文摘 | Zhao Y W Zhang G X | 2002 | Journal of Materials Processing Technology2002，129，13： | 1 |
| 16 | Seismic force modification factors for modified-clough hysteretic models显示文摘 | TONG G S ZHAO Y F | 2007 | En gineering Structures2007，29，11： | 1 |
| 17 | Moment methods for structural reliability 显示文摘 | Zhao Y G Ono T | 2001 | Structural Safety2001，23，1： | 1 |
| 18 | Preparation and characterization of arnino-functionalized nano-Fe3O4 magnetic polymer adsorbents for removal of chromium(VI) ions显示文摘 | Zhao Y G Shen H Y Pan S D | 2010 | Journal of Materials Science2010，45，： | 1 |
| 19 | Synthesis of cyanohydron trimethylsilyl ethers of aeylferrocenes显示文摘 | Bian Z X Zhao H Y Li B G | 2003 | Poly- hedron2003，22，： | 1 |
| 20 | TiN/TiC Multi-layer Films Deposited by Pulse Biased Arc Ion Plating显示文摘 | ZHAO Y H LIN G Q XIAO J Q | 2010 | Vacuum2010，85，1： | 1 |
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