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| 1 | ^(40)Ar-^(39)Ar dating and geological implication of auriferous altered rocks from the middle-deep section of Q875 gold-quartz vein in Xiaoqinling area, Henan,China显示文摘The 40Ar-39Ar age method is employed in this work to analyze the auriferous altered rocks from the middle-deep section of the Q875 gold-quartz vein in the Xiao-qinling area, and the results show that the main gold deposition of the Q875 occurred in ca. 128-126 Ma. As a typical gold-bearing quartz vein in this gold-rich area, the age data obtained from the Q875 also constrain on the metallogenic time of the lode gold deposits developed in the same geological settings. This geochronological study supplies new evidence for further understanding the timing of gold mineralization, the genesis of gold deposits and the geodynamic settings in Xiaoqinling area. | WANG Yitian, MAO Jingwen, LU Xinxiang & YE AnwangInstitute of Mineral Resources, Chinese Academy of Geological Sciences, Beijing 100037, China Institute of Geological Sciences, Henan Province, Zhengzhou 450053, China Lingbao Bureau of Geology and Mineral | 2002 | Chinese Science Bulletin2002，47，20： | 36 |
| 2 | Current status of endoscopic retrograde cholangiopancreatography in patients with surgically altered anatomy显示文摘Endoscopic retrograde cholangiopancreatography(ERCP)in patients with surgically altered anatomy must be performed by a highly experienced endoscopist.The challenges are accessing the afferent limb in different types of reconstruction,cannulating a papilla with a reverse orientation,and performing therapeutic interventions with uncommon endoscopic accessories.The development of endoscopic techniques has led to higher success rates in this group of patients.Device-assisted ERCP is the endoscopic procedure of choice for high success rates in short-limb reconstruction;however,these success rate is lower in long-limb reconstruction.ERCP assisted by endoscopic ultrasonography is now popular because it can be performed independent of the limb length;however,it must be performed by a highly experienced and skilled endoscopist.Stent deployment and small stone removal can be performed immediately after ERCP assisted by endoscopic ultrasonography,but the second session is needed for other difficult procedures such as cholangioscopy-guided electrohydraulic lithotripsy.Laparoscopic-assisted ERCP has an almost 100%success rate in longlimb reconstruction because of the use of a conventional side-view duodenoscope,which is compatible with standard accessories.This requires cooperation between the surgeon and endoscopist and is suitable in urgent situations requiring concomitant cholecystectomy.This review focuses on the advantages,disadvantages,and outcomes of various procedures that are suitable in different situations and reconstruction types.Emerging new techniques and their outcomes are also discussed. | Chonlada Krutsri Mitsuhiro Kida Hiroshi Yamauchi Tomohisa Iwai Hiroshi Imaizumi Wasaburo Koizumi | 2019 | World Journal of Gastroenterology2019，25，26： | 23 |
| 3 | 放射生物学概念在鼻咽癌、食管癌及肺癌治疗中的应用显示文摘The term 'altered factionation' is relative to the conventonal fractionation, which is defined as follows: for curative treatment of most cancers, 180 to 200 cGy per fraction is given once a day, 5 times per week, to a total dose determined by the tumor being treated and the tolerance of critical normal tissues within the target volume, usually 60 to 70 Gy within 6~7 weeks. The basic rationales for altered fractionation can be summaried by (1) The late-responding tissues are much more sensitive to fraction size than the early-responding tissues, with multiple smaller fractions. The late responding tissues can tolerate an increased total dose and the effects on the tumor therefore may be increased by the higher total radiation dose with improved tumor control; (2) Reduction in overall treatment time decreases the opportunity of accelerated regeneration of tumor cells during treatment and therefore inceases the probability of tumor control for a given total dose. In general,altered fractionation schemes can be categoriclly divided in to the following:(1) Hypofraction(2) Split-course radiation therapy(3) Hyperfractionation(4) Accelerated fractionation(5) Accelerated hyperfractionationIn recently years, we have tested various altered fractionation schedules for the treatment of nasopharyngeal, esophageal and lung cancer. For the nasopharyngeal caricnoma, hyperfractionation was used firstly by 1.1 Gy/F, 2F/day with an interval of >6hrs, followed by concomitant boost to a total dose of 74 Gy within 6 weeks. In lung cancer, the program was 1.15~1.25 Gy per fraction, two fractions per day for a total dose of 70 Gy with overall treatment time about 6 to 7 weeks. Esophageal cancer, conventional fractionation was given to total dose about 41 Gy followed by a boost for an additional 28 Gy by 1.5 Gy per fraction twice daily with overall treatment time about 6.3 weeks.Our preliminary treatment data showed that the local tumor control rates were higher in these study groups than the conventional groups and the acute reactions were increased as expected but tolerable. The main points of altered fractionation radiation schedules are also discussed. | 何少琴 | 1995 | 中华放射肿瘤学杂志1995，4，1： | 16 |
| 4 | Innovations and techniques for balloon-enteroscopeassisted endoscopic retrograde cholangiopancreatography in patients with altered gastrointestinal anatomy显示文摘Endoscopic retrograde cholangiopancreatography(ERCP) remains challenging in patients who have undergone surgical reconstruction of the intestine.Recently,many studies have reported that balloonenteroscope-assisted ERCP(BEA-ERCP) is a safe and effective procedure.However,further improvements in outcomes and the development of simplified procedures are required.Percutaneous treatment,Laparoscopy-assisted ERCP,endoscopic ultrasoundguided anterograde intervention,and open surgery are effective treatments.However,treatment should be noninvasive,effective,and safe.We believe that these procedures should be performed only in difficult-to-treat patients because of many potential complications.BEA-ERCP still requires high expertiselevel techniques and is far from a routinely performed procedure.Various techniques have been proposed to facilitate scope insertion(insertion with percutaneous transhepatic biliary drainage(PTBD) rendezvous technique,Short type single-balloon enteroscopes with passive bending section,Intraluminal injection of indigo carmine,CO2 inflation guidance),cannulation(PTBD or percutaneous transgallbladder drainage rendezvous technique,Dilation using screw drill,Rendezvous technique combining DBE with a cholangioscope,endoscopic ultrasound-guided rendezvous technique),and treatment(overtube-assisted technique,Short type balloon enteroscopes) during BEA-ERCP.The use of these techniques may allow treatment to be performed by BEA-ERCP in many patients.A standard procedure for ERCP yet to be established for patients with a reconstructed intestine.At present,BEA-ERCP is considered the safest and most effective procedure and is therefore likely to be recommended as firstline treatment.In this article,we discuss the current status of BEA-ERCP in patients with surgically altered gastrointestinal anatomy. | Hiroshi Yamauchi Mitsuhiro Kida Hiroshi Imaizumi Kosuke Okuwaki Shiro Miyazawa Tomohisa Iwai Wasaburo Koizumi | 2015 | World Journal of Gastroenterology2015，21，21： | 9 |
| 5 | An integrated ore prospecting model for the Nyasirori gold deposit in Tanzania显示文摘The Nyasirori gold deposit,located in the middle-western end of the Musoma-Mara Archean greenstone belt in Tanzania,is a tectonic altered rock type gold deposit controlled by shear tectonic zone.This work conducted high-precision ground magnetic measurements to delineate fault structures and favorable prospecting targets,utilized induced polarization(IP)intermediate gradient to roughly determine the distribution and extension of the tectonic altered zone and gold ore(mineralized)bodies,and further carried out IP sounding and magnetotelluric sounding to locate the tectonic altered zone and gold ore(mineralized)bodies.The anomalous gradient belt of the combination of positive and negative micromagnetic measurements reflects the detail of shallow surface tectonic alteration zone and gold mineralization body.Micromagnetic profile anomalies indicate the spatial location and occurrence of concealed tectonic alteration zone and gold(mineralized)ore bodies.Soil geochemical measurements indicate that the ore-forming element Au correlates well with As and Sb,and As and Sb anomalies have a good indication to gold orebodies.Based on the multi-source geological-geophysical-geochemical information of the Nyasirori gold deposit,this work established an integrated prospecting model and proposed a set of geophysical and geochemical methods for optimizing prospecting targets. | Yang-sen Yuan Shui-ping Li Jun Peng Jian-tao Si Hua Cheng Jin Sun Jian-zheng Wei Jiang-bo Shao | 2019 | China Geology2019，2，4： | 6 |
| 6 | Risk factors for perforation during endoscopic retrograde cholangiopancreatography in post-reconstruction intestinal tract显示文摘BACKGROUND Endoscopic retrograde cholangiopancreatography(ERCP) in patients with surgically altered anatomy has been a major challenge to gastrointestinal endoscopists with low success rates for reaching the target site as well as high complication rates. The knowledge of ERCP-related risk factors is important for reducing unexpected complications.AIM To identify ERCP-related risk factors for perforation in patients with surgically altered anatomy.METHODS The medical records of 187 patients with surgically altered anatomy who underwent ERCP at our institution between April 2009 and December 2017 were retrospectively reviewed. An analysis of patient data, including age, sex, type of reconstruction, cause of surgery, aim of ERCP, success rate of reaching target site,success rate of procedure, adverse events, type of scope, time to reach the target site, and duration of procedure, was performed. In patients with Billroth-Ⅱ reconstruction, additional potential risk factors were the shape of the inserted scope and whether the anastomosis was antecolic or retrocolic.RESULTS All patients(n = 187) had surgical anatomy, such as Billroth-Ⅰ(n = 22), Billroth-Ⅱ(n = 33), Roux-en-Y(n = 54), Child, or Whipple reconstruction(n = 75). ERCP was performed for biliary drainage in 43 cases(23%), stone removal in 29 cases(16%),and stricture dilation of anastomosis in 59 cases(32%). The scope was unable to reach the target site in 17 cases(9%), and an aimed procedure could not be accomplished in 54 cases(29%). Adverse events were pancreatitis(3%),hyperamylasemia(10%), cholangitis(6%), cholestasis(4%), excessive sedation(1%), perforation(2%), and others(3%). Perforation occurred in three cases, all of which were in patients with Billroth-Ⅱ reconstruction; in these patients, further analysis revealed loop-shaped insertion of the scope to be a significant risk for perforation(P = 0.01).CONCLUSION Risk factors for perforation during ERCP in patients with surgically altered anatomy were Billroth-Ⅱ reconstruction and looping of the scope during BillrothⅡ procedure. | Shinichi Takano Mitsuharu Fukasawa Hiroko Shindo Ei Takahashi Sumio Hirose Yoshimitsu Fukasawa Satoshi Kawakami Hiroshi Hayakawa Hiroshi Yokomichi Makoto Kadokura Tadashi Sato Nobuyuki Enomoto | 2019 | World Journal of Clinical Cases2019，7，1： | 6 |
| 7 | Anal cancer in Chinese:human papillomavirus infection and altered expression of p53显示文摘AnalcancerinChinese:humanpapilomavirusinfectionandalteredexpressionofp53LAIMaoDe,LUOMinJie,YAOJianErandCHENPeiHuiSubject... | LAI MaoDe, LUO MinJie, YAO JianEr and CHEN PeiHuiKeywords anus neoplasms papillomavirus infection DNA, viral p53 gene gene expression polymerase chain reaction | 1998 | World Journal of Gastroenterology1998，4，4： | 4 |
| 8 | THE CENTRAL CAMPANATO SPACES AND ITS APPLICATION显示文摘Let 1<p<∞,α≥0 and K be a local field.In this paper,the author introduces the spaces J_p^a(K)and the central Campanato spaces C)_a,p(K)as well as the S_p,a-and S_p,a^+-type singular integrals.Then,the author investigates the behavior of these singular integrals and their altered operators on these spaces. | Yang Dachun (Beijing Normal University,China) | 1994 | Analysis in Theory and Applications1994，10，4： | 3 |
| 9 | Epidemiologic study of the irritable bowel syndrome in Beijing: stratified randomized study by cluster sampling显示文摘 | 潘国宗 鲁素彩 柯美云 韩少梅 郭慧平 方秀才 | 2000 | Chinese Medical Journal2000，，1： | 3 |
| 10 | Contribution of purinergic receptors to spinal cord injury repair:stem cellbased neuroregeneration显示文摘Traumatic spinal cord injury(SCI),defined as physical trauma to the spinal column yielding altered motor,sensory,or autonomic function,is a devastating neurological disease causing major impact at both personal and societal level.SCI is characterized by a primary insult(compression,contusion or laceration)followed by a secondary | Rosa Gomez-Villafuertes | 2016 | Neural Regeneration Research2016，11，3： | 3 |
| 11 | Endoscopic retrograde cholangiopancreatography in patients with altered anatomy: How to deal with the challenges?显示文摘Endoscopic retrograde cholangiopancreatography(ERCP) in patients with surgically altered anatomy is challenging. Several operative interventions of both the gastrointestinal tract and the biliary and/or pancreatic system lead to altered anatomy, rendering ERCP more difficult or even impossible with a conventional side-viewing duodenoscope. Adapted endoscopes are avail-able to reach the biliopancreatic system and to perform ERCP in patients with altered anatomy. However, both technical difficulties and complications determine the procedure's success. Different technical approaches have been described and are highly dependent on local expertise and endoscopic equipment. Standard-ized practical guidelines are currently unavailable. This review focuses on the challenges encountered during ERCP in patients with altered anatomy and how to deal with them. The first challenge is reaching the papilla or the bilioenteric/pancreatoenteric anastomosis in the patient with postoperative altered anatomy. The sec-ond challenge is the cannulation of the biliopancreatic system and performing all conventional ERCP interven-tions and the third challenge is the control of possible complications. The available literature data on this topicis reviewed and illustrated with clinical cases. | Tom G Moreels | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，8： | 3 |
| 12 | Endoscopic ultrasound-guided interventions in specialsituations显示文摘Endoscopic ultrasound(EUS) was introduced in 1982 and has since become a popular advanced procedure for diagnosis and therapeutic intervention. Initially, EUS was most commonly used for the diagnosis of pancreatobiliary diseases and tissue acquisition. EUS was first used for guided cholangiography in 1996, followed by EUS-guided biliary drainage in 2001. Advancements in equipment and endoscopic accessories have led to an expansion of EUS-guided procedures, which now include EUS-guided drainage of intra-abdominal abscesses or collections, intravascular treatment of refractory variceal and nonvariceal bleeding, transmural pancreatic drainage, common bile duct stone clearance, enteral feeding tube placement and entero-enteric anastomosis. Patients with surgically altered upper gastrointestinal anatomies have greatly benefited from EUS also. This systematic review describes and discusses EUS procedures performed in uncommon diseases and conditions, as well as applications on more vulnerable patients such as young children and pregnant women. In these cases, routine approaches do not always apply, and thus may require the use of innovative and unconventional techniques. Increased knowledge of such special applications will help increase the success rates of these procedures and provide a foundation for additional advances and utilizations of the technique. | Varayu Prachayakul Pitulak Aswakul | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，2： | 2 |
| 13 | Bone morphogenetic protein-7 negatively regulates insulin signal transduction in C2C12 myotubes and Hep G2 hepatocytes显示文摘Objective To investigate the effects of bone morphogenetic protein-7(BMP7)on insulin signaling transduction in C2C12 myotubes and Hep G2 hepatocytes,and to study the underlying mechanisms preliminarily.Methods The C2C12 myotubes and Hep G2 cells were treated with BMP7 at different concentrations.The insulin | 姚丽丽 | 2016 | China Medical Abstracts(Internal Medicine)2016，33，2： | 1 |
| 14 | PHENOTYPIC CHARACTERISTICS OF HUMAN BLOOD MONOCYTE SUBPOPULATIONS IN PSORIASIS AND ATOPIC DERMATITIS: EVIDENCE FOR DIFFERENTIAL EXPRESSION OF SURFACE MOLECULES显示文摘Peripheral blood monocytes seem to be of importance for the initiation and maintenance of the psoriatic tissue reaction. Hyperproliferation of monocytopoiesis as well as functional abnormalities of monocytes in psotiasis have previously been described. We sought to determine whether peripheral blood monocyte subpopulations from patients with psoriasis show altered phentypes. and how the | M Zheng U Mrowietz E Christophers | 1995 | Chinese Medical Journal1995，，3： | 1 |
| 15 | Recent trends in endoscopic management of achalasia显示文摘Esophageal achalasia is a chronic and progressive motility disorder characterized by absence of esophageal body peristalsis associated with an impaired relaxation of lower esophageal sphincter(LES) and usually with an elevated LES pressure, leading to an altered passage of bolus through the esophago-gastric junction. A definitive cure for achalasia is currently unavailable. Palliative treatment options provide only food and liquid bolus intake and relief of symptoms. Endoscopic therapy for achalasia aims to disrupt or weaken the lower esophageal sphincter. Intra-sphincteric injection of botulinum toxin is reserved for elderly or severely ill patients. Pneumatic dilation provides superior results than botulinum toxin injection and a similar mediumterm efficacy almost comparable to that attained after surgery. Per oral endoscopic myotomy is a promising option for treating achalasia, but it requires increased experience and further objective and long-term follow up. This article will review different endoscopic treatments in achalasia, and summarize the short-term and long-term outcomes. | Salvatore Tolone Paolo Limongelli Gianmattia del Genio Luigi Brusciano Antonio Russo Lorenzo Cipriano Marco Terribile Giovanni Docimo Roberto Ruggiero Ludovico Docimo | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，9： | 1 |
| 16 | Mobility of elements during lamprophyre alteration and altered fluid characteristics in the Zhenyuan gold deposit显示文摘LAMPROPHYRES are one of the rock types which are easily subject to alteration. Alteration can not onlychange their texture and mineral assemblage, but also influence their geochemistry properties. The mostavailable data show that alteration will directly influence the content of Au in lamprophyre. For example,in the Superior area of Canada and the Yilgan area of Australia relatively fresh lamprophyres are bothlow in Au contents (3.9×10-9 and 1.7×10-9, respectively), but the contents of Au in altered lamprophyres from both areas are double increased (38×10-9 and 20×10-9 on average). Lamprophyres arewidely exposed in the Zhenyuan gold deposit, Yunnan Province and they are closely associated with goldmineralization both in space and in time. So the lamprophyres in the Zhenyuan gold deposit can be citedas the most typical example both at home and abroad. Lamprophyres in the mining district have undergonevarying-degree alteration and partly experienced mineralization. On the basis of the mass equilibrium e- | HUANG Zhilong, LlU Congqiang and XlAO Huayun Open Laboratory of Ore Deposit Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, China | 1999 | Chinese Science Bulletin1999，44，S2： | 1 |
| 17 | Effects of high glucose on in vitro invasiveness of human breast cancer cell line MDA-MB-435显示文摘Objective To explore the effects and underlying mechanisms of high glucose on in vitro invasiveness of human breast cancer cell line MDA-MB-435. Methods The invasiveness of MDA-MB-435 was determined by Matrigel-coated transwell chambers. | 李军涛 | 2013 | China Medical Abstracts(Internal Medicine)2013，30，1： | 0 |
| 18 | Pancreas显示文摘2012095 Effect of bone marrow mesenchymal stem cells transplantation on intestinal mucosa barrier of acute pancreatitis. SUN Xuecheng(孙学成),et al.Dept Gastroenterol,1st Affil Hosp,Wenzhou Med Coll, | 段伟宏 | 2012 | China Medical Abstracts(Internal Medicine)2012，0，1： | 0 |
| 19 | THE EFFECT OF GAMMA IRRADIATION in vitro ON PHYSICOCHEMICAL PROPERTIES OF COPPER-ZINC SUPEROXIDE DISMUTASE显示文摘In a previous paper we have pointed out that irradiation could bring about the decrease of copper-zinc SOD activity both in vitro and in vivo. Whether its physicochemical properties would also be altered has not been reported. Here we report that gamma irradiation in vitro affected obviously its properties, which reflected the damage of molecular structure and active center of the enzyme. | 方允中 刘智峰 李益新 | 1985 | Chinese Science Bulletin1985，30，2： | 0 |
| 20 | Nutritional Support in the ICU显示文摘Starvation is not a desirable part of the treatment in the ICU.This is in particular true for patients with preexisting disease and perhaps malnutrition already when entering the unit.In addition critical illness in itself imposes a high metabolic demand upon the patient. Inparticular protein metabolism is dramatically altered in order to provide a metabolic state which gives the criticall ill patients the best possilbilities for survival and recovery. This priority is given at the expense of in particular skeletal musele proteins, which are sacrificed during | Jan wevnerman MD.P.HD. | 1993 | 中华临床营养杂志1993，11，3： | 0 |
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