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| 1 | Copper-chelating therapeutic effect in Wilson disease with different clinical phenotypes and polymorphisms of ATP7B gene显示文摘CopperchelatingtherapeuticefectinWilsondiseasewithdiferentclinicalphenotypesandpolymorphismsofATP7BgeneRENMingShan1,HUWen?.. | REN MingShan1, HU WenBin1, ZHANG Zhi1, JU ShuangWu1, FAN YuXin2, WANG GongQiang1 and YANG RenMin1Keywords Wilson disease/therapy copper chelating agents ATP7B gene mutations | 1998 | World Journal of Gastroenterology1998，4，4： | 15 |
| 2 | Influence of Methionine Supplementation in Chelation of Lead in Rats1显示文摘The influence of methionine supplementation on the efficacy of common antidotes to lead poisoning, calcium disodium ethylenediaminetetraacetate (CaNa2EDTA) and D-penicillamine (DPA), was investigated in rats. The animals were given lead acetate (0.1% in drinking water) for 12 weeks and thereafter treated with CaNa2EDTA, DPA (0.3mmol/kg, intraperitoneally), DL-methionine (1.34 mmol/kg, intragastrically), or the combination of a chelating agent and methionine for 3 days. While chelating agents enhanced the urinary excretion of Pb, methionine increased the fecal excretion of Pb significantly. Treatment with the combination of a chelating agent and methionine did not potentiate the effect of each antidote. However, methionine supplementation increased the efficacy of both chelating agents in reducing the hepatic and renal Pb burden but not the blood Pb level. The Pb-induced inhibition of blood δ-aminolevulinic acid dehydratase activity and the increase in urinary excretion of δ-aminolevulinic acid were reversed to a certain extent by CaNa2EDTA, DPA, and methionine but the combination did not improve their individual performances. The beneficial effects of methionine may be attributed to its ability to increase the bioavailability of glutathione (GSH), useful in chelating Pb and counteracting the toxic effects, as evidenced by restoration of the Pb-induced decrease in hepatic GSH level by treatment with methionine. Methionine may be useful as a supportive therapy in chelation of Pb. (c)1989 Academic Press. Inc. | DEVENDRAN.KACHRU SHASHIKHANDELWAL SUSHILK.TANDON | 1989 | Biomedical and Environmental Sciences1989，2，3： | 1 |
| 3 | SURFACE STATE OF COPPER ELECTRODE IN SOLUTION OF POTASSIUM PYROPHOSPHATE显示文摘Pyrophosphate as chelating agent has been extensively used in the practice of the electrodeposition of metals. Especially the use of pyrophosphate copper plating is universal. The study of electrode processes in this system, however, is insufficient; moreover there are some disagreements on it. | 秦尔华 谷林锳 | 1982 | Chinese Science Bulletin1982，27，9： | 1 |
| 4 | SYNTHESES AND ADSORPTION PROPERTIES OF NEW CHELATING RESINS CONTAINING SULFUR AND NITROGEN ATOMS显示文摘Chelating resins that contain sulfur and nitrogen atoms as the coordinating sites to metal ions exhibit good adsorption properties for transition metals, especially for precious metals. Because the organic sulfur and nitrogen compounds are generally defined as soft or intermediate bases, while the precious metal ions as soft and intermediate acids, they can easily combine to form stable complexes. | 徐羽梧 杨杰 董世华 | 1989 | Chinese Science Bulletin1989，34，15： | 1 |
| 5 | Synthesis and Adsorption Studies on Magnetic Microbeads of Polythioether-arylamine Resins显示文摘By the suspended condensation reaction of poly(choloromethyl thiirane) with o-tolidine and o-dianisidine respectively, two new microbeads of magnetic chelating resins were synthesized by usingγ-Fe2O3 as magnetic core. Their adsorption properties for Hg(Ⅱ), Cu( Ⅱ ) , Zn( Ⅱ ) , Pb( Ⅱ ) , Au( Ⅲ ) , Pd( Ⅱ ) , Pt (Ⅳ ) and Ag( Ⅰ ) were investigated. The microbeads possess excellent adsorbability for Hg( Ⅱ) and noble metal ions, and predominantly adsorbed Pd( Ⅱ) or Hg(Ⅱ) in the coexistence of Cu ( Ⅱ ), Zn( Ⅱ ) andMg(Ⅱ). The experimental results demonstrate that resin Ⅱ with lower N and S contents has higher adsorption capacities for noble metal ions than resin Ⅰ, which shows the dianisidine group in resin Ⅱ plays an important role in the adsorption , due to the synergistic effects of methoxyl and amino group in adjacent position. | 张超灿 | 2001 | Journal of Wuhan University of Technology(Materials Science)2001，16，3： | 1 |
| 6 | THE USE OF CHELATING RESIN FOR THE PRE-CONCENTRATION OF TRACE RARE EARTH ELEMENTS IN BIOLOGICAL SAMPLES AND THEIR DETERMINATION显示文摘Macroporous amino-carboxvlic chelating resin of acrylic acid series may concentrate trace rare earth inthe presence of 0.1 mol/l α-hydroxy-isobutyric acid at pH 4.5.With 0.10 mol/l HCl as eluant rare earthmay be eluted quantitatively and separated from Ca,Mg,Fe and Cu.This method is used to determine traceamount of rare earth in human hair,stone (in kidney and bladder),peanut,grape,strawberry,cucumber,pigliver and other biological samples. | 祝孝丰 张田 扆军 | 1990 | Journal of Rare Earths1990，8，2： | 0 |
| 7 | SYNTHESIS AND STRUCTURE DETERMINATION OF NEODYMIUM COMPLEXES WITH CYCLOHEXANECARBOXYLIC ACID显示文摘Two complexes,NdL3·2C2H5OH and NdL3·2H2O where L=cyclohexane-carboxylate anion,weresynthesized and the structure of the former was determined by the single-crystal X-ray diffration method.The crystal is triclinic,Pspace group with the cell parameters:a=1.2385(6),b=1.2385(6),c=0.9421(5)nm.α=91.69(4)°,β=98.49(4)°,γ=99.16(5)°,Z=2,V=1.436 nm3.The structure was refined to Rvalue of 0.0866.Each Nd atom is connected with other two Nd atoms by two bidentate and two tridentatecarboxyl groups to form a linear polymer.The Nd atom is further coordinated by a chelating carboxyl andtwo ethanol molecules.So the central atom is nine-coordinated with a distorted monocappedsquare-antiprism geometry.The infrared spectra and the thermal analysis of the complexes were alsostudied. | 张德龙 黄春辉 徐光宪 杨健 林秀云 林政炯 | 1990 | Journal of Rare Earths1990，8，3： | 0 |
| 8 | Preparation and Preliminary Biological Evaluation of c-Gluc-Lys([Al18F]NOTA)-TOCA显示文摘The humanized monoclonal antibodies(mAbs)h-R3 has been used as a targeting biomolecule better than other anti-EGFR(epidermal growth factor receptor)for the delivery of radionuclide onto tumor cells in radio immunotherapy(RIT).Several bifunctional chelating agents(BCAs)could be used as a bridge coupling h-R3 and radiometals.In this study,h-R3 was conjugated with S-2-(4-isothiocyanatobenzyl)-1,4, | DENG Xin-rong FAN Cai-yun LUO Zhi-fu | 2013 | Annual Report of China Institute of Atomic Energy2013，，1： | 0 |
| 9 | ADSORPTION PROPERTY OF FH-1 HUMIC RESIN显示文摘Humic resin is a new type of weak acid cation exchanging resin. Its production procedure is: Frist, mix humic acid solution proportionally with special organic high-molecular compound. Then, use calcium salt for gelation. Finally, condense and dry it at low temperature. The resin is characteristic of great adsorption capacity, resisting interference from Ca2+ and Mg2+, efficient purification and available life span. It is suitable for use in treatment of waste water containing heavy metallic ions such as Hg2+, Pb2+, Cd2+,Cu2+,Zn2+,Ni2+ and Cr3+. Its working principle is as follows: Active function groups like carboxyl group and phenolic pydroxyl group contained in molecular structure humic resin can react with heavy metallic ions in ionic exchange, complexing (or chelating)and surface adsorption, forming certain | 巴音 王兰 | 1984 | Chinese Science Bulletin1984，29，7： | 0 |
| 10 | Preparation of Chelating Cellulose Filters and Their Application to the Separation and Enrichment of Trace Elements显示文摘PreparationofChelatingCelluloseFiltersandTheirApplicationtotheSeparationandEnrichmentofTraceElementsLIUChun-ming(Departmentof... | LIU Chun-ming(Department of Changchun Normal College, Changchun,130032)GUO Yi-hang and ZHAO Xiao-liang(Center for Analysis and Testing, Northeast Normal University, Changchun, 130024) DING Lan(Center for Analysis and Testing ,Jilin University, Changchun, | 1995 | Chemical Research in Chinese Universities1995，11，4： | 0 |
| 11 | Mobilization of Lead by Several Chelating Agents in Mice Injected with Lead显示文摘The relative abilities of several chelating agents to act as antagonists for acute and chronic lead poisoning have been examined in the mouse.The acute LD50 for lead acetate trihydrate was determined and found to be 135.3 mg Pb/kg for i. p. injection with a 95% confidence interval of 87.1 to 210.3 mg Pb/kg. The relative efficacy of chelating agents to reduce liver,kidney, spleen, bone and brain levels of lead was determined. The spleen levels were found to undergo little differences between the control and treated groups, but the liver, kidney, bone and brain levels showed significant differences in some cases. Of the compounds examind, meso-2, 3-dimercaptosuccinic acid (DMSA)and sodium 2,3-dimercaptopropane-1-sulfonate(DMPS) were as effective as disodium calcium ethylenediaminetetraacetate (Na2CaEDT A). The resuits indicated that DMSA was a promising chelating agent and may be worthy of further investigation in the clinic. | 徐兆发 Mark M.Jones | 1989 | 中国医科大学学报1989，18，S2： | 0 |
| 12 | SYNTHESIS OF SILICAS-SUPPORTED POLYETHYLENEIMINE AND ITS ADSORPTION PROPERTIES显示文摘In this paper,a silicas-supportedpolyethyleneimine resin is synthesized and its adsorption proper-ties are studied.Its selectivity of sorbing heavy metal ion willvary considerablly as the pH value of solution varies.In hy- drochloric acid,the resin only sorbs Au(III).This suggests thatthe resin is applicable to the separation of copper(II)or gold(III). | 张超灿 李曦 庞金兴 王成刚 | 1994 | Journal of Wuhan University of Technology(Materials Science)1994，9，4： | 0 |
| 13 | A feasibility study on cleaning Pb-contaminated soil with chelating agents显示文摘AfeasibilitystudyoncleaningPb-ontaminatedsoilwithchelatingagentsZhuKun(DepartmentofEnvironmentalEngineering,LanzhouRailwayCol... | Zhu Kun(Department of Environmental Engineering, Lanzhou Railway College, Lanzhou 730070, China)Chen Hui(Departinent of Chemistry, Northwest Nornial Univeroity, Lanzhou 730070. China) | 1994 | Journal of Environmental Sciences1994，6，1： | 0 |
| 14 | THE DISSOCIATION CONSTANTS OF 1-ACETAMIDO PROPYLIDENE- 1,1-DIPHOSPHONIC ACID AND 1-PROPIONAMIDO ETHYLIDENE- 1,1-DIPHOSPHONIC ACID显示文摘The Gem-Diphosphonic acids are a kind of multiple usage chelating agents. 1-acetamido propylidene-1,1-diphishonic acid (S-186) and 1-propoinamido ethylidene-1,1-diphosphonic acid (S-106) were first made by the Shanghai In- | 罗勤慧 蒋凝 谢毓元 | 1983 | Chinese Science Bulletin1983，28，11： | 0 |
| 15 | Effects of iron chelation therapy on allogeneic hematopoietic stem cell transplantation in myelodysplastic syndrome patients with iron overload显示文摘Objective To investigate the effects of iron chelation therapy on hematopoietic reconstitution and related complications of allogeneic hematopoietic stem cell transplantation(allo-HSCT)in patients with myelodysplastic syndrome(MDS).Methods Various clinical parameters were analyzed retrospectively in 57 MDS patients | 顾彩红 | 2016 | China Medical Abstracts(Internal Medicine)2016，33，2： | 0 |
| 16 | SYNTHESES AND PROPERTIES OF A CHELATING RESIN WITH MERCAPTO GROUPS显示文摘Chelating resins with thiol as functionalgroup were synthesized from poly(β-chloroethyl gly-cidyl ether).and adsorption of Au(Ⅲ).Pd(Ⅱ),Pt(Ⅳ),Hg(Ⅱ).Cu(Ⅱ)and Pb(Ⅱ)on the resinswas also investigated.Both resins show high affinityfor Au(Ⅲ),Pd(Ⅱ),Pt(Ⅳ)and Hg(Ⅱ)within abroad range of hydrochloric acid.Results of static anddynamic tests indicate the possibility of separation ofAn(Ⅲ),Pd(Ⅱ),Pt(Ⅳ)and Hg(Ⅱ)from highconcentrations of acid and neutral salt from high con-centrations of acid and neutral salt solution. | 张超灿 | 1993 | Journal of Wuhan University of Technology(Materials Science)1993，8，4： | 0 |
| 17 | SPECTROPHOTOMETRIC STUDY OF THE COLOR REACTION OF RARE EARTHS——AMINO CACID CHLORPHOSPHORAZO-CETYL PYRIDINE BROMIDE显示文摘I. INTRODUCTION Recently, the utilization of the chelating properties of triphenylmethane dyes in the presence of surfactants for speetrophotometric determination of rare earth ions has received a great deal of attention. Those systems, which are generally much more sensitive than similar reactions in the absence of surfactants, are not satisfactory in selectivity as reactions are produced in neutral or weak acidic solution. | 过乃蓉 罗庆尧 陈震华 曾云鹗 | 1983 | Chinese Science Bulletin1983，28，9： | 0 |
| 18 | IMPROVEMENT OF BLEACHING OF KAOLIN USING CHELATING AGENTS显示文摘Bleaching of the kaolin ore from Shaziling Kaolin Mine in Jiangxi Province of China was studied with the aim of enhancing the quality and value of the ore to meet the requirements from the ceramics manufacturers. Factors affecting the reductive bleaching of kaolin ore with sodium dithionite as the bleaching agent were studied and optimized to increase the whiteness of the kaolin ore from 38. 5% to about 65%. However, it was found that in the conventional bleaching process, a washing step to remove the ferrous | 龚文琪 | 1997 | Journal of Wuhan University of Technology(Materials Science)1997，12，Z1： | 0 |
| 19 | SYNTHESES AND ADSORPTION PROPERTIES OF POLYMER RESINS CONTAINING BENZIDINE AND ITS DERIVATIVES显示文摘Three chelating resins were prepared by re-acting poly (β-chloroethyl glycidyl ether) with benzidine, o-tolidine and o-dianisidine respectively, and their structureswere confirmed by IR spectra and elementary analyses. Theadsorption properties of the resins for Au (Ⅲ), Pd (Ⅱ). Pt(Ⅳ),Hg(Ⅱ) .Cu(Ⅱ),Pb(Ⅱ) and Zn(Ⅱ) were also investi-gated. The results show that the resin incorporating o-diani-sidine exhibits high affinity for Au (Ⅲ) within a broad rangeof hydrochloric acid .and selectively sorbs Au (Ⅲ) in the coexistance of Cu(Ⅱ), Zn(Ⅱ) and Mg (Ⅱ). Desorption of Au(Ⅲ),Pd (Ⅱ) and Pt (Ⅳ) sorbed proceeded quantitatively us-ing 0. 1 mol/l hydrochloric acid containing 2%-10% thioureaas desorbents. | 张超灿 谢海安 庞金兴 李曦 熊传溪 | 1995 | Journal of Wuhan University of Technology(Materials Science)1995，10，3： | 0 |
| 20 | ON THE SYNTHESES OF BENZIDINE CHELATE RESINS CONSISTING OF POLYETHER BACKBONE AND THEIR ADSORPTION PROPERTIES显示文摘Three new resins are synthesized by thereaction of polyepichlorohydrin with benzidine, 0-toli-dine and 0-dianisidine, respectively. Their adsorptionproperties for Au (Ⅲ), Pd (Ⅱ), Pt (Ⅳ), Hg (Ⅱ), Cu(Ⅱ), Pb (Ⅱ) and Zn (Ⅱ) are investigated. The resincontaining 0-dianisidine group selectively sorbed Au (Ⅲ)in the presence of transition metal ions. The results showthat synergistic effect of anchor groups plays an impor-tant role in the adsorption of metal ions. | 张超灿 宠金兴 李曦 候昌健 | 1995 | Journal of Wuhan University of Technology(Materials Science)1995，10，1： | 0 |
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