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| 1 | Bioconjugated Silica Nanoparticles: Development and Applications显示文摘Advanced bioanalysis,including accurate quantitation,has driven the need to understand biology and medicine at the molecular level.Bioconjugated silica nanoparticles have the potential to address this emerging challenge.Particularly intriguing diagnostic and therapeutic applications in cancer and infectious disease as well as uses in gene and drug delivery,have also been found for silica nanoparticles.In this review,we describe the synthesis,bioconjugation,and applications of silica nanoparticles in different bioanalysis formats,such as selective tagging,barcoding,and separation of a wide range of biomedically important targets.Overall,we envisage that further development of these nanoparticles will provide a variety of advanced tools for molecular biology,genomics,proteomics and medicine. | Lin Wang Wenjun Zhao Weihong Tan | 2008 | Nano Research2008，1，2： | 15 |
| 2 | Advanced methodologies for the cleaning of works of art显示文摘Cultural heritage assets constitute a fundamental socioeconomic resource,but the actual works of art need to be maintained,counteracting degradation processes,to transfer these benefits to future generations.In particular,the removal of soil,aged coatings,and vandalism/overpaints is one of the most needed interventions in art restoration.Traditional cleaning methodologies,based on classical solution and polymer chemistry,only grant limited control of the cleaning interventions,with the risk of affecting the original components of the artifacts,and often involving the use of toxic or non-environmentally friendly compounds.Alternatively,materials science,colloids,and soft matter have provided valuable and safe solutions in the last decades.This review provides a selection of the most recent and advanced methodologies for the wet cleaning of works of art,spanning from nanostructured cleaning fluids(microemulsions,surfactants swollen micelles)to physical and chemical gels.The new methodologies work on different physico-chemical mechanisms,such as processes for detaching/dewetting,to selectively remove the unwanted layers in sustainable and cost-effective interventions.The best performing systems,like microemulsions confined in“twin-chain”polyvinyl alcohol gels,have been assessed in the cleaning of masterpieces such as works by Pablo Picasso,Jackson Pollock and Roy Lichtenstein.Particular attention is dedicated to“green”chemistry systems,using low-toxicity solvents or bio-based/waste materials to build gel networks.Finally,current trends and future perspectives are given,showing that advanced systems for art cleaning link with transversal fields of crucial importance even beyond Cultural heritage conservation,e.g.,detergency,tissue engineering,drug-delivery,food industry and cosmetics. | CASINI Andrea CHELAZZI David BAGLIONI Piero | 2023 | Science China(Technological Sciences)2023，66，8： | 1 |
| 3 | Advances in the design and development of SARS-CoV-2 vaccines显示文摘Since the end of 2019,coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has spread worldwide.The RNA genome of SARS-CoV-2,which is highly infectious and prone to rapid mutation,encodes both structural and non-structural proteins.Vaccination is currently the only effective method to prevent COVID-19,and structural proteins are critical targets for vaccine development.Currently,many vaccines are in clinical trials or are already on the market.This review highlights ongoing advances in the design of prophylactic or therapeutic vaccines against COVID-19,including viral vector vaccines,DNA vaccines,RNA vaccines,live-attenuated vaccines,inactivated virus vaccines,recombinant protein vaccines and bionic nanoparticle vaccines.In addition to traditional inactivated virus vaccines,some novel vaccines based on viral vectors,nanoscience and synthetic biology also play important roles in combating COVID-19.However,many challenges persist in ongoing clinical trials. | Xue-Liang Peng Ji-Si-Yu Cheng Hai-Lun Gong Meng-Di Yuan Xiao-Hong Zhao Zibiao Li Dai-Xu Wei | 2022 | Military Medical Research2022，9，4： | 1 |
| 4 | Preface to Special Issue on Nanoscience and Catalysis显示文摘Over the past decade, to meet the ever increased demand on high‐performance catalysts with excellent activity, selectivity and stability, the nanocatalysts and catalysis have been rigorously explored, resulting in a noticeable progress in new paradigm of nanoscience and nanotechnology for catalysis. Differing remarkably from conventional bulk catalysts, size shrinkage of active components to nanometer scale gives a rise to significantly increased catalytic activity, owing to the high surface‐to‐volume ratio of small particles as well as a large fraction of active atoms with dangling bonds exposed surfaces. In addition, other unique properties of nanomaterials such as surface‐ and strain‐driven lattice distortion, variation in electronic state density and oxidation‐induced charge redistribution could also benefit the catalytic performance. | 唐智勇 赵惠军 | 2017 | Chinese Journal of Catalysis2017，38，6： | 0 |
| 5 | Special Issue on future directions in plasma nanoscience显示文摘Over the past 20 years,plasma nanoscience has become a mature and vibrant field.It deals with both the fundamental science and applications of low-temperature plasmas,ion beams,lasers,and related approaches and how this relates to the fabrication,synthesis,modification,and integration in and of nanoscale materials,structures and functional devices.The complexity often encountered in research in this field intrinsically calls for both fundamental and applied research,both experimental and theoretical.Plasma nanoscience,therefore,is a highly multidisciplinary field,bringing together researchers from physics,chemistry,medicine,engineering,biochemistry,informatics and more. | Erik C.Neyts | 2019 | Frontiers of Chemical Science and Engineering2019，13，2： | 0 |
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