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| 1 | O-FIB:far-field-induced near-field breakdown for direct nanowriting in an atmospheric environment显示文摘Nanoscale surface texturing,drilling,cutting,and spatial sculpturing,which are essential for applications,including thin-film solar cells,photonic chips,antireflection,wettability,and friction drag reduction,require not only high accuracy in material processing,but also the capability of manufacturing in an atmospheric environment.Widely used focused ion beam(FIB)technology offers nanoscale precision,but is limited by the vacuum-working conditions;therefore,it is not applicable to industrial-scale samples such as ship hulls or biomaterials,e.g.,cells and tissues.Here,we report an optical far-field-induced near-field breakdown(O-FIB)approach as an optical version of the conventional FIB technique,which allows direct nanowriting in air.The writing is initiated from nanoholes created by femtosecondlaser-induced multiphoton absorption,and its cutting“knife edge”is sharpened by the far-field-regulated enhancement of the optical near field.A spatial resolution of less than 20 nm(λ/40,withλbeing the light wavelength)is readily achieved.O-FIB is empowered by the utilization of simple polarization control of the incident light to steer the nanogroove writing along the designed pattern.The universality of near-field enhancement and localization makes O-FIB applicable to various materials,and enables a large-area printing mode that is superior to conventional FIB processing. | Zhen-Ze Li Lei Wang Hua Fan Yan-Hao Yu Qi-Dai Chen Saulius Juodkazis Hong-Bo Sun | 2020 | Light(Science & Applications)2020，9，1： | 24 |
| 2 | Recent advances of microneedles for biomedical applications: drug delivery and beyond显示文摘The microneedle(MN), a highly efficient and versatile device, has attracted extensive scientific and industrial interests in the past decades due to prominent properties including painless penetration, low cost, excellent therapeutic efficacy, and relative safety. The robust microneedle enabling transdermal delivery has a paramount potential to create advanced functional devices with superior nature for biomedical applications. In this review, a great effort has been made to summarize the advance of microneedles including their materials and latest fabrication method, such as three-dimensional printing(3DP). Importantly, a variety of representative biomedical applications of microneedles such as disease treatment, immunobiological administration, disease diagnosis and cosmetic field, are highlighted in detail. At last, conclusions and future perspectives for development of advanced microneedles in biomedical fields have been discussed systematically. Taken together, as an emerging tool, microneedles have showed profound promise for biomedical applications. | Jian Yang Xinli Liu Yunzhi Fu Yujun Song | 2019 | Acta Pharmaceutica Sinica B2019，9，3： | 21 |
| 3 | Surgical treatment for both-column acetabular fractures using pre-operative virtual simulation and three-dimensional printing techniques显示文摘Background:Surgical treatment of both-column acetabular fractures is challenging because of the complex acetabular fracture patterns and the curved surface of the acetabulum.Seldom study has compared the application of three-dimensional(3D)printing technology and traditional methods of contouring plates intra-operatively for the surgical treatment of both-column acetabular fractures.We presented the use of both 3D printing technology and a virtual simulation in pre-operative planning for both-column acetabular fractures.We hypothesized that 3D printing technology will assist orthopedic surgeons in shortening the surgical time and improving the clinical outcomes.Methods:Forty patients with both-column acetabular fractures were recruited in the randomized prospective case-control study from September 2013 to September 2017 for this prospective study(No.ChiCTR1900028230).We allocated the patients to two groups using block randomization(3D printing group,n=20;conventional method group,n=20).For the 3D printing group,1:1 scaled pelvic models were created using 3D printing,and the plates were pre-contoured according to the pelvic models.The plates for the conventional method group were contoured during the operation without 3D printed pelvic models.The operation time,instrumentation time,time of intra-operative fluoroscopy,blood loss,number of times the approach was performed,blood transfusion,post-operative fracture reduction quality,hip joint function,and complications were recorded and compared between the two groups.Results:The operation and instrumentation times in the 3D printing group were significantly shorter(130.8±29.2 min,t=-7.5,P<0.001 and 32.1±9.5 min,t=-6.5,P<0.001,respectively)than those in the conventional method group.The amount of blood loss and blood transfusion in the 3D printing group were significantly lower(500[400,800]mL,Mann-Whitney U=74.5,P<0.001 and 0[0,400]mL,Mann-Whitney U=59.5,P<0.001,respectively)than those in the conventional method group.The number of the approach performed in the 3D printing group was significantly smaller than that in the conventional method group(pararectus+Kocher-Langenbeck[K-L]approach rate:35%vs.85%;x2=10.4,P<0.05).The time of intra-operative fluoroscopy in the 3D printing group was significantly shorter than that in the conventional method group(4.2±1.8 vs.7.7±2.6 s;t=-5.0,P<0.001).The post-operative fracture reduction quality in the 3D printing group was significantly better than that in the conventional method group(good reduction rate:80%vs.30%;x2=10.1,P<0.05).The hip joint function(based on the Harris score 1 year after the operation)in the 3D printing group was significantly better than that in the conventional method group(excellent/good rate:75%vs.30%;χ^2=8.1,P<0.05).The complication was similar in both groups(5.0%vs.25%;χ^2=3.1,P=0.182).Conclusions:The use of a pre-operative virtual simulation and 3D printing technology is a more effective method for treating bothcolumn acetabular fractures.This method can shorten the operation and instrumentation times,reduce blood loss,blood transfusion and the time of intra-operative fluoroscopy,and improve the post-operative fracture reduction quality. | Ji-Hui Huang Hui Liao Xin-Yu Tan Wei-Rong Xing Qi Zhou Yu-Shi Zheng Hong-Yu Cao Can-Jun Zeng | 2020 | Chinese Medical Journal2020，，4： | 15 |
| 4 | A Review of Printable Flexible and Stretchable Tactile Sensors显示文摘Flexible and stretchable tactile sensors that are printable,nonplanar,and dynamically morphing are emerging to enable proprioceptive interactions with the unstructured surrounding environment.Owing to its varied range of applications in the field of wearable electronics,soft robotics,human-machine interaction,and biomedical devices,it is required of these sensors to be flexible and stretchable conforming to the arbitrary surfaces of their stiff counterparts.The challenges in maintaining the fundamental features of these sensors,such as flexibility,sensitivity,repeatability,linearity,and durability,are tackled by the progress in the fabrication techniques and customization of the material properties.This review is aimed at summarizing the recent progress of rapid prototyping of sensors,printable material preparation,required printing properties,flexible and stretchable mechanisms,and promising applications and highlights challenges and opportunities in this research paradigm. | Kirthika Senthil Kumar Po-Yen Chen Hongliang Ren | 2019 | Research2019，，1： | 12 |
| 5 | A minimally invasive alternative for the treatment of nutcracker syndrome using individualized three-dimensional printed extravascular titanium stents显示文摘Background: This study was designed to evaluate the clinical and radiographic outcomes of patients with nutcracker syndrome (NCS) who were treated with three-dimensional printing (3DP) extravascular titanium stents (EVTSs). The 3DP EVTS was expected to release the hypertension of the left renal vein (LRV) produced by its compression between the superior mesenteric artery (SMA) and the aorta without causing any complications. Method: The pre-operative kidney model of each patient was printed out to enable surgical planning. After that, the EVTS was designed based on the LRV’s primitive physiologic structure using computer-aided design software, and each stent was printed out with a precision setting of 20 μm. Seventeen patients who had been suffering from NCS underwent laparoscopic 3DP EVTS placement. The surgical procedure was designed for the placement of EVTS, taking great care in positioning and fixing the stent. Surgical data, which included patient demographic characteristics as well as pre- and post-operative test results, were collected and analyzed. Results: The mean duration of surgery was 75 ± 9 min, and the mean blood loss was 20 ± 5 mL. Computed tomography examinations revealed that the pre- and post-operative angle between the SMA and the aorta ranged from 18.7°± 4.3° to 48.0°± 8.8°(P < 0.05);in patients with left varicocele, the mean diameter of the left spermatic vein ranged from 3.7 ± 0.5 to 1.3 ± 0.2 mm (P < 0.05). Moreover, Doppler ultrasound examinations showed that the peak velocity of blood flow at the hilar area ranged from 12.4 ± 3.3 to 18.5 ± 3.4 cm/s (P < 0.05). No side effects were observed in the 24 to 42 months following surgery. Conclusion: The findings after 2 years of follow-up suggest that the 3DP EVTS is a safe and effective minimally invasive alternative for the treatment of NCS. | He Wang Yi-Tong Guo Yong Jiao Da-Li He Bin Wu Li-Jun Yuan Yan-Yan Li Yong Yang Tie-Sheng Cao Bo Zhang | 2019 | Chinese Medical Journal2019，，12： | 12 |
| 6 | Transfer printing techniques for flexible and stretchable inorganic electronics显示文摘Transfer printing is an emerging deterministic assembly technique for micro-fabrication and nano-fabrication,which enables the heterogeneous integration of classes of materials into desired functional layouts.It creates engineering opportunities in the area of flexible and stretchable inorganic electronics with equal performance to conventional wafer-based devices but the ability to be deformed like a rubber,where prefabricated inorganic semiconductor materials or devices on the donor wafer are required to be transfer-printed onto unconventional flexible substrates.This paper provides a brief review of recent advances on transfer printing techniques for flexible and stretchable inorganic electronics.The basic concept for each transfer printing technique is overviewed.The performances of these transfer printing techniques are summarized and compared followed by the discussions of perspectives and challenges for future developments and applications. | Changhong Linghu Shun Zhang Chengjun Wang Jizhou Song | 2018 | npj Flexible Electronics2018，2，1： | 11 |
| 7 | Applying Neural-Network-Based Machine Learning to Additive Manufacturing:Current Applications,Challenges,and Future Perspectives显示文摘Additive manufacturing(AM),also known as three-dimensional printing,is gaining increasing attention from academia and industry due to the unique advantages it has in comparison with traditional subtractive manufacturing.However,AM processing parameters are difficult to tune,since they can exert a huge impact on the printed microstructure and on the performance of the subsequent products.It is a difficult task to build a process-structure-property-performance(PSPP)relationship for AM using traditional numerical and analytical models.Today,the machine learning(ML)method has been demonstrated to be a valid way to perform complex pattern recognition and regression analysis without an explicit need to construct and solve the underlying physical models.Among ML algorithms,the neural network(NN)is the most widely used model due to the large dataset that is currently available,strong computational power,and sophisticated algorithm architecture.This paper overviews the progress of applying the NN algorithm to several aspects of the AM whole chain,including model design,in situ monitoring,and quality evaluation.Current challenges in applying NNs to AM and potential solutions for these problems are then outlined.Finally,future trends are proposed in order to provide an overall discussion of this interdisciplinary area. | Xinbo Qi Guofeng Chen Yong Li Xuan Cheng Changpeng Li | 2019 | Engineering2019，5，4： | 11 |
| 8 | Preliminary application of 3D-printed coplanar template for iodine-125 seed implantation therapy in patients with advanced pancreatic cancer显示文摘AIM To evaluate a 3 D-printed coplanar template for iodine-125 seed implantation therapy in patients with pancreatic cancer. METHODS A retrospective analysis of our database was performed, and a total of 25 patients with pancreatic cancer who underwent iodine-125 seed implantation between January 2014 and November 2017 were analyzed. Of these, 12 implantations were assisted by a 3 D-printed coplanar template(group A), and 13 implantations performed freehand were selected as a control group(group B). A 3 D coplanar template was designed and printed according to a preoperative CT scan and treatment planning system. The iodine-125 seeds were then implanted using the template as a guide. Dosimetric verification was performed after implantation. Pre-and postoperative D90, V100, and V150 were calculated. The success rate of iodine-125 seed implantation, dosimetric parameters, and complications were analyzed and compared between the two groups.RESULTS Iodine-125 seed implantation was successfully performed in both groups. In group A, the median pre-and postoperative D90 values were 155.32 ± 8.05 Gy and 154.82 ± 16.43 Gy, respectively; the difference between these values was minimal and not statistically significant(P > 0.05). Postoperative V100 and V150 were 91.05% ± 4.06% and 64.54% ± 13.40%, respectively, which met the treatment requirement. A better dosimetric parameter was observed in group A than in group B, and the difference was statistically significant(V100: 91.05% ± 4.06% vs 72.91% ± 13.78%, P < 0.05). No major procedure-related complications were observed in either group. For group A, mild hemorrhage was observed in 1 patient with a peritoneal local hematoma due to mesenteric vein damage from the iodine-125 seed implantation needle. The hematoma resolved spontaneously without treatment. Postoperative blood amylase levels remained within the normal range for all patients.CONCLUSION A 3 D-printed coplanar template appears to be a safe and effective iodine-125 seed implantation guidance tool to improve implantation accuracy and optimize dosimetric distribution. | Wei Huang Jian Lu Ke-Min Chen Zhi-Yuan Wu Qing-Bin Wang Jing-Jing Liu Ju Gong Zhi-Jin Chen Xiao-Yi Ding Zhong-Min Wang | 2018 | World Journal of Gastroenterology2018，24，46： | 10 |
| 9 | Mechanical and dielectric properties of porous and wave-transparent Si3N4–Si3N4 composite ceramics fabricated by 3D printing combined with chemical vapor infiltration显示文摘Porous Si3N4–Si3N4 composite ceramics were fabricated by 3D printing combined with low-pressure chemical vapor infiltration(CVI).This technique could effectively improve the designability of porous Si3N4 ceramics and optimize the mechanical and dielectric properties.The effects of process parameters including the deposition time and heat treatment on the microstructure and properties of porous Si3N4–Si3N4 composite ceramics were studied.The study highlights following:When CVI processing time was increased from 0 to 12 h,the porosity decreased from68.65%to 26.07%and the density increased from 0.99 to 2.02 g/cm3.At the same time,the dielectric constant gradually increased from 1.72 to 3.60;however,the dielectric loss always remained less than0.01,indicating the excellent electromagnetic(EM)wave-transparent performance of porous Si3N4–Si3N4 composite ceramics.The maximum flexural strength of 47±2 MPa was achieved when the deposition time attained 6 h.After heat treatment,the porosity increased from 26.07%to 36.02%and the dielectric constant got a slight increase from 3.60 to 3.70 with the dielectric loss still maintaining lower than 0.01.It has been demonstrated that the porous Si3N4–Si3N4 composite ceramics are a promising structural and EM wave-transparent material suitable for high temperature service. | Zanlin CHENG Fang YE Yongsheng LIU Tianlu QIAO Jianping LI Hailong QIN Laifei CHENG Litong ZHANG | 2019 | Journal of Advanced Ceramics2019，8，3： | 10 |
| 10 | Laser-driven programmable non-contact transfer printing of objects onto arbitrary receivers via an active elastomeric microstructured stamp显示文摘Transfer printing, as an important assembly technique, has attracted much attention due to its valuable merits to develop novel forms of electronics such as stretchable inorganic electronics requiring the heterogeneous integration of inorganic materials with soft elastomers. Here, we report on a laser-driven programmable non-contact transfer printing technique via a simple yet robust design of active elastomeric microstructured stamp that features cavities filled with air and embedded under the contacting surface, a micro-patterned surface membrane that encapsulates the air cavities and a metal layer on the inner-cavity surfaces serving as the laser-absorbing layer. The micro-patterned surface membrane can be inflated dynamically to control the interfacial adhesion, which can be switched from strong state to weak state by more than three orders of magnitude by local laser heating of the air in the cavity with a temperature increase below 100℃. Theoretical and experimental studies reveal the fundamental aspects of the design and fabrication of the active elastomeric microstructured stamp and the operation of non-contact transfer printing. Demonstrations in the programmable transfer printing of micro-scale silicon platelets and micro-scale LED chips onto various challenging receivers illustrate the extraordinary capabilities for deterministic assembly that are difficult to address by existing printing schemes, thereby creating engineering opportunities in areas requiring the heterogeneous integration of diverse materials such as curvilinear electronics and Micro LED displays. | Hongyu Luo Chengjun Wang Changhong Linghu Kaixin Yu Chao Wang Jizhou Song | 2020 | National Science Review2020，7，2： | 9 |
| 11 | Three-dimensional(3D) Printing Technology Assisted by Minimally Invasive Surgery for Pubic Rami Fractures显示文摘The feasibility of three-dimensional (3D) printing technology cgmbined with minimally invasive surgery in the treatment of pubic rami fractures was explored.From August 2015 to October 2017,a series of 30 patients who underwent surgical stabilization of their anterior pelvic ring (all utilizing the 3D printing technology)by one surgeon at a single hospital were studied.The minimally invasive incisions were made through anterior inferior cilia spine and pubic nodule.Data collected included the operative duration,the blood loss,the damage of the important tissue,the biographic union and therecovery of the function after the operation.Measurements on inlet and outlet pelvic cardiograph were made immediately post-operation and at all follow-up clinic visits.The scores of reduction and function were measured during follow-up.Results showed that the wounds of 30 patients were healed in the first stage,and there was no injury of important structures such as blood vessels and nerves.According to the Matta criteria,excellent effectiveness was obtained in 22 cases and good in 8 cases.According to the functional evaluation criteria of Majeed,excellent effectiveness was obtained in 21 cases and good in 9 cases.It was suggested that the 3D printing technology assisted by minimally invasive surgery can better evaluate the pelvic fracture before operation,which was helpful in plate modeling, and can shorten surgery duration and reduce intraoperative blood loss and complications. The positioning accuracy was improved,and better surgical result was finally achieved. | Wen-bo NIE Fa-gang YE Jian-lin MA Jiang-ping YU Ming-xing WANG Zhen-hua ZHANG Fu-jie SUN | 2018 | Current Medical Science2018，38，5： | 8 |
| 12 | Recent progress in 4D printing of stimuli-responsive polymeric materials显示文摘4D printing is proposed based on the additive manufacturing of stimuli-responsive materials and structures,which can realize shape changing upon external stimuli.This article reviews the 4D printing methods and actuating performances of 4D printing structures based on shape memory polymers,hydrogels,liquid crystal elastomers,and electroactive polymers.This article shows that the shape morphing properties of single materials are limited,while 4D printing of composites can integrate the various driving modes of different smart materials.In the end,challenges facing 4D printing such as broadening the scope of smart materials,improving printing processes,the compatibility of printing different materials have been discussed. | MA SuQian ZHANG YunPeng WANG Meng LIANG YunHong REN Lei REN LuQuan | 2020 | Science China(Technological Sciences)2020，63，4： | 7 |
| 13 | Emerging micro-additive manufacturing technologies enabled by novel optical methods显示文摘This paper presents a comprehensive review of recent advances in micro-additive manufacturing enabled by novel optical methods with an emphasis on photopolymerization-based printing processes.Additive manufacturing,also known as three-dimensional(3D)printing,has become an important engineering solution to construct customized components or functional devices at low cost.As a green manufacturing technology,3D printing has the advantages of high energy efficiency,low material consumption,and high precision.The rapid advancement of 3D printing technology has broadened its applications from laboratory research to industrial manufacturing.Generally,3D objects to be printed are constructed digitally[e.g.,via computer-aided design(CAD)programs]by connecting a 3D dot array,where a dot is defined as a voxel through mechanical,electrical,or optical means.The voxel size ranges from a few orders of magnitude of the wavelength of light to the sub-diffraction limit,achieved by material nonlinearity and precise power thresholding.In recent years,extensive research in optical additive manufacturing has led to various breakthroughs in quality,rate,and reproducibility.In this paper,we review various micro-3D printing techniques,including single-photon and two-photon processes,with a focus on innovative optical methods,e.g.,ultrafast beam shaping,digital holography,and temporal focusing.We also review and compare recent technological advances in serial and parallel scanning systems from the perspectives of resolution,rate,and repeatability,where the strengths and weaknesses of different methods are discussed for both fundamental and industrial applications. | WEI LIN DIHAN CHEN SHIH-CHI CHEN | 2020 | Photonics Research2020，8，12： | 7 |
| 14 | Characteristics and techniques of GaN-based micro-LEDs for application in next-generation display显示文摘Due to the excellent optoelectronic properties,fast response time,outstanding power efficiency and high stability,micro-LED plays an increasingly important role in the new generation of display technology compared with LCD and OLED display.This paper mainly introduces the preparation methods of the GaN-based micro-LED array,the optoelectronic characteristics,and several key technologies to achieve full-color display,such as transfer printing,color conversion by quantum dot and local strain engineering. | Zhou Wang Xinyi Shan Xugao Cui Pengfei Tian | 2020 | Journal of Semiconductors2020，41，4： | 7 |
| 15 | Recent advances on 3D printing graphene-based composites显示文摘3D printing or additive manufacturing (AM) has revolutionized the way of manufacturing by designing complex structures in a customized feature which cannot be realized by traditional processing methods. Incoming materials are trying to adopt 3D printing techniques which directly fabricate sophisticated entities with multifunctionality like mechanical, electrical, thermal and magnetic properties etc. For the realization of advanced materials, 3D printing techniques are emerging from single material to composite materials manufacturing by simply introducing the nano- and micro-reinforcements with the matrix. In this review, we provide an outline of 3D printing graphene-based composites according to various AM techniques including fused deposition modeling (FDM), direct ink writing (DIW), stereolithography (SLA) and selective laser sintering (SLS). First a brief introduction of various AM techniques is given to get a basic understanding of the principles of 3D printing, and then the fabrication process, structural characteristics and applications of different 3D printing techniques for graphene-based composites are summarized. In addition, some effective simulation and characterization methods are also included. We hope that this review would clarify the potential of AM techniques for composite materials and can open new prospects for designing of novel materials. | Haichang Guo Ruicong Lv Shulin Bai | 2019 | Nano Materials Science2019，1，2： | 6 |
| 16 | 3D-printed surface promoting osteogenic differentiation and angiogenetic factor expression of BMSCs on Ti6Al4V implants and early osseointegration in vivo显示文摘Three-dimensional-printed(3 D-P) titanium implants display many advantages, such as design flexibility,higher efficiency, the capability to easily construct complex or customized structures, etc., and is believed to potentially replace traditional implants. However, the biological performance of the 3 D-P titanium surface has not been investigated systematically. Herein, we analyzed the surface characteristics of 3 D-P Ti6 Al4 V implants and evaluated the biological responses of bone marrow derived mesenchymal stromal cells(BMSCs) to the 3 D-P surface in vitro. Moreover, after implantation into the rat femoral condyle for3 and 6 weeks, the osseointegration performance was evaluated. The results showed the 3 D-P Ti6 Al4 V implant presented distinct fluctuant macroscale rough surface and relatively better hydrophilicity which enhanced the adhesion, proliferation, osteogenic differentiation and angiogenetic factor expression of BMSCs. Moreover, the in vivo osseointegration performance was also better than that of the control group at the early stage. The present study suggested the 3 D-P titanium alloy is a promising candidate to be used as implant material. | Jinkai Zhang Wenhui Zhou Hui Wang Kaili Lin Fengshan Chen | 2019 | Journal of Materials Science & Technology2019，35，2： | 6 |
| 17 | Experimental investigation on the cracking behavior of 3D printed kinked fissure显示文摘Uniaxial compression tests were carried out for 3 D printed samples having various types of kinked fissures by using the rock mechanics servo-controlled testing system. Photo-elastic technique is adopted to characterize and visualize the stress distribution and evolution of 3 D printed models subjected to vertical compression. The stress field in the loading process can clearly be captured via a high-speed camera. The results showed that fringes around the kinked fissure tips formed a central symmetrical interference fringe pattern, and failure firstly occurred at interference fringe of highest order. Two failure types i.e. tip-cracking and non-tip-cracking are categorized on the basis of crack propagation pattern of 3 D printed samples. Tensile crack propagation of wing cracks is the main form of failure of the antisymmetric kinked fissures, but the inclination of the branch fissures also played a key role on the location of initial fracture. The finite element method was applied to numerically simulate the process of crack propagation. The isochromatic fringe patterns are in good agreement with the experimental investigation. The current work gives an insight for implication of advanced technique to quantify and visualize the distribution of stress field, and provides further understanding of kinked fissure behavior at failure. | MA GuoWei DONG QianQian WANG Li | 2018 | Science China(Technological Sciences)2018，61，12： | 6 |
| 18 | Application of a 3D-printed ”fistula stent” in plugging enteroatmospheric fistula with open abdomen: A case report显示文摘BACKGROUND Open abdomen(OA) has been generally accepted for its magnificent superiority and effectiveness in patients with severe trauma, severe intra-abdominal infection, and abdominal compartment syndrome. In the meantime, OA calls for a mass of nursing and the subsequent enteroatomospheric fistula(EAF), which is one of the most common complications of OA therapy, remains a thorny challenge.CASE SUMMARY Our team applied thermoplastic polyurethane as a befitting material for producing a 3 D-printed 'fistula stent' in the management of an EAF patient,who was initially admitted to local hospital because of abdominal pain and distension and diagnosed with bowel obstruction. After a series of operations and OA therapy, the patient developed an EAF.CONCLUSION Application of this novel 'fistula stent' resulted in a drastic reduction in the amount of lost enteric effluent and greatly accelerated rehabilitation processes. | Zi-Yan Xu Hua-Jian Ren Jin-Jian Huang Zong-An Li Jian-An Ren | 2019 | World Journal of Gastroenterology2019，25，14： | 6 |
| 19 | 高职环境艺术设计教学中的3D打印技术的应用——以立体构成课程为例显示文摘3D打印(3D printing,又称三维打印)是一种快速成形技术,它以数字化模型为基础,运用粉末状金属或塑料等可粘合材料,通过逐层打印的方式构造物体。3D打印应用于环境艺术设计教学将是一个全新的教育手段,3D打印技术能将学生的一些限于纸面的构思转化为物体模型,让创意变为现实,让抽象变成具象。更能够冲击学生的感官认识,并留下深刻印象,增加学习兴趣,提高学习效率,拓展了想象力,提高学生的潜在创作力。 | 詹松 | 2016 | 现代装饰(理论)2016，0，8： | 6 |
| 20 | 3D printing of calcium phosphate bioceramic with tailored biodegradation rate for skull bone tissue reconstruction显示文摘The bone regenerative scaffold with the tailored degradation rate matching with the growth rate of the new bone is essential for adolescent bone repair.To satisfy these requirement,we proposed bone tissue scaffolds with controlled degradation rate using osteoinductive materials(Ca-P bioceramics),which is expected to present a controllable biodegradation rate for patients who need bone regeneration.Physicochemical properties,porosity,compressive strength and degradation properties of the scaffolds were studied.3D printed Ca-P scaffold(3DS),gas foaming Ca-P scaffold(FS)and autogenous bone(AB)were used in vivo for personalized beagle skull defect repair.Histological results indicated that the 3DS was highly vascularized and well combined with surrounding tissues.FS showed obvious newly formed bone tissues.AB showed the best repair effect,but it was found that AB scaffolds were partially absorbed and degraded.This study indicated that the 3D printed Ca-P bioceramics with tailored biodegradation rate is a promising candidate for personalized skull bone tissue reconstruction. | Boqing Zhang Huan Sun Lina Wu Liang Ma Fei Xing Qingquan Kong Yujiang Fan Changchun Zhou Xingdong Zhang | 2019 | Bio-Design and Manufacturing2019，2，3： | 5 |
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