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| 1 | High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa显示文摘It has been reported that ACE2 is the main host cell receptor of 2019-nCoV and plays a crucial role in the entry of virus into the cell to cause the final infection. To investigate the potential route of 2019-n Cov infection on the mucosa of oral cavity, bulk RNA-seq profiles from two public databases including The Cancer Genome Atlas(TCGA) and Functional Annotation of The Mammalian Genome Cap Analysis of Gene Expression(FANTOM5 CAGE) dataset were collected. RNA-seq profiling data of 13 organ types with para-carcinoma normal tissues from TCGA and 14 organ types with normal tissues from FANTOM5 CAGE were analyzed in order to explore and validate the expression of ACE2 on the mucosa of oral cavity. Further, single-cell transcriptomes from an independent data generated in-house were used to identify and confirm the ACE2-expressing cell composition and proportion in oral cavity. The results demonstrated that the ACE2 expressed on the mucosa of oral cavity. Interestingly, this receptor was highly enriched in epithelial cells of tongue. Preliminarily, those findings have explained the basic mechanism that the oral cavity is a potentially high risk for 2019-nCoV infectious susceptibility and provided a piece of evidence for the future prevention strategy in dental clinical practice as well as daily life. | Hao Xu Liang Zhong Jiaxin Deng Jiakuan Peng Hongxia Dan Xin Zeng Taiwen Li Qianming Chen | 2020 | International Journal of Oral Science2020，12，1： | 69 |
| 2 | Constructal optimization for geometry of cavity by taking entransy dissipation minimization as objective显示文摘The entransy dissipation extremum principle provides new warranty and criterion for optimization of heat transfer.For two cases(body with heat generation and body heated externally)of a solid conducting wall with an open cavity,a dimensionless equivalent thermal resistance based on entransy dissipation definition was taken as the optimization objective to optimize the model constructal ge- ometry.Numerical results validated the necessity and feasibility of the presented method.Comparisons of the numerical results based on minimization of dimensionless maximum thermal resistance and minimization of dimensionless equivalent thermal resistance,respectively,showed that there was no obvious difference between the two results when the volume fractionΦoccupied by cavity was small, but the difference between the two results increased with the increases ofΦand the body aspect ratio H/L for any model.The optimal cavities for bodies heated externally were more slender than those for bodies with heat generation.Heat origin had obvious effect on the global performance of heat transfer. The entransy dissipation of body heated externally increased 2―3 times than that of body with heat generation,indicating that the global performance of heat transfer weakened.The method presented herein provides some guidelines for some relevant thermal design problems. | XIE ZhiHui CHEN LinGen SUN FengRui | 2009 | Science China(Technological Sciences)2009，52，12： | 37 |
| 3 | 耳后带蒂肌骨膜瓣及自体骨粉在开放式乳突根治术腔填塞术中的应用研究显示文摘开放式乳突根治术是治疗中耳胆脂瘤及骨疡型中耳炎的主要手术方式,但手术后留下的宽大乳突术腔及外耳道后壁缺损给患者带来诸多不便,部分患者难以获得干耳,并影响听力重建的效果。外耳道后上壁重建术是消除开放式乳突术腔的常用手术方式,我们先前曾利用自体耳屏软骨重建外耳道后上壁及上鼓室外侧壁,术后获得接近正常的外耳道生理功能,但随着随访时间的延长, | 董吕华 毛华杰 赵波 | 2017 | 中国耳鼻咽喉头颈外科2017，24，8： | 18 |
| 4 | THE INFLUENCE OF CAVITY DAMAGE ON MECHANICAL PROPERTIES OF SUPERPLASTICALLY-DEFORMED MATERIALS AND ITS PREDICTION显示文摘Aluminium alloy LY12CZ sheet without any pre-treatment has been used to study the influence of cavity damage on the mechanical properties of the superplastically-deformed materials room temper- ature. The experimental results show that: (1) the lower the rate of cavitation as the superplastic strain increases, the higher the superplasticity is; (2) the mechanical properties of superplastically- deformed materials at room temperature decrease as the superplastically-deformed strain increases, especially, a noteworthy decrease in elasticity modulus, yield strenth and ultimate strength at room temperature begins to appear as the level of cavitation by area comes up to about 4%, while at the same level the reduction in area drops down a very large quantity. Then, a three-layer back- propagation neural network has been developed to predict the machanichl properties of the superplasti- cally-deformed material.The results acquired from the neural network are very | M. B. Liu, Z. C. Zhao,H. Gao,M. Q. Li and S. C. Wu College of Materials Science and Engineering, Northwestern Polytechnical University, Xi’an 710072, China | 2000 | Acta Metallurgica Sinica(English Letters)2000，13，2： | 18 |
| 5 | Recent progress on ULF wave and its interactions with energetic particles in the inner magnetosphere显示文摘The global distribution properties of Ultra Low Frequency wave (ULF) in the inner magnetospgere and its interactions with energetic particles, such as the wave-particle resonance, modulation, and particle acceleration, are active topics in space physics research. These problems are fundamentally important issues to understand the energy transport from the solar wind into the magnetosphere. In this paper we briefly reviewed the recent research progress on ULF wave and its interactions with energetic particles in the inner magnetosphere; furthermore, we suggested some open questions for future study. | Theodore A. FRITZ | 2008 | Science China(Technological Sciences)2008，51，10： | 16 |
| 6 | 鼻腔NK/T细胞淋巴瘤的CT和MRI影像学表现显示文摘目的:探讨鼻腔NK/T细胞淋巴瘤的CT和MRI影像学特征,提高诊断水平。方法:搜集经手术病理证实的鼻腔NK/T细胞淋巴瘤19例,全部病例均有CT和/或MRI资料。结果:病变位于鼻腔左侧7例,右侧11例,双侧同时侵犯1例;局限于鼻前庭或鼻前部3例,鼻腔前中部6例,中后部2例,整个鼻腔受侵8例;肿瘤向鼻前庭生长并浸润鼻翼、鼻背及邻近面颊部皮肤11例;延伸至口咽部1例,侵犯眼眶2例,伴骨质破坏9例。CT显示肿瘤呈软组织密度充填鼻腔并沿鼻黏膜蔓延,MRI显示肿瘤T1WI呈等或稍低信号,T2WI呈不均匀稍高信号,增强后呈轻到中度不均匀强化。结论:鼻腔NK/T细胞淋巴瘤的影像学表现有一定特征性,CT扫描可清晰显示骨质破坏情况,MRI能够更清晰、准确显示病变侵犯范围。确诊须依赖病理学和免疫组化检查。 | 唐勇 林薇 曹林德 布桂林 张建梅 | 2010 | 医学影像学杂志2010，20，12： | 15 |
| 7 | Cavity length below chute aerators显示文摘It is proved that air entrainment is one of the efficient measures dealing with cavi-tation control for the release works of hydropower projects. There are many factors to be considered in designing a chute aerator. One of the most important factors concerns the cavity length below the aerator,which has outstanding effects on air entrainment against cavitation damage. It is crucial to determine reasonable emergence angle for the calculation of the cavity length. In the present paper the overall effects of structural and hydraulic parameters on the emergence angle of the flow from the aerator were analyzed. Four improved expressions of the emer-gence angle with weight coefficient were investigated through experimental data of 68 points observed from 12 aerators of 6 hydropower projects,of both model and prototype,on the basis of error theory. A method to calculate the cavity length be-low aerators was suggested,which considers overall effects of the above men-tioned parameters. Comparison between the method in this paper and the other five methods of calculating the cavity length showed that the present method is much more reliable than the existing methods while the mean error of the method is less than others. | WU JianHua RUAN ShiPing | 2008 | Science China(Technological Sciences)2008，51，2： | 14 |
| 8 | Helicobacter pylori colonization of the oral cavity:Amilestone discovery显示文摘Over the past several years, the severity of Helicobacter pylori(H. pylori) infections has not significantly diminished. After successful eradication, the annual H. pylori recurrence rate is approximately 13% due tooral H. pylori infection. Established clinical diagnostic techniques do not identify an oral etiologic basis of H. pylori prior to gastric infection. There has been disagreement as to whether oral infection of H. pylori exists or not, with no definite conclusion. In medical practice, negative results with the urea breath test suggest that the stomach infection of H. pylori is cured in these patients. In fact, patients can present negative urea breath test results and yet exhibit H. pylori infection due to oral infection. The present paper provides evidence that H. pylori oral infection is nonetheless present, and the oral cavity represents a secondary site for H. pylori colonization. | John KC Yee | 2016 | World Journal of Gastroenterology2016，22，2： | 13 |
| 9 | Numerical study on ULF waves in a dipole field excited by sudden impulse显示文摘A three-dimensional numerical model is employed to investigate ULF waves ex-cited by the sudden impulse (SI) of the solar wind dynamic pressure interacting with a dipole magnetosphere. We focus on the solar wind-magnetosphere energy coupling through ULF waves, and the influences of the SI spectrum on the cavity mode structure and the energy deposition due to field line resonances (FLRs) in the magnetosphere. The numerical results show that for a given SI lasting for 1 min with amplitude of 50 mV/m impinging on the subsolar magnetopause, the total ULF energy transported from the solar wind to the magnetosphere is about the magni-tude of 1014 J. The efficiency of the solar wind energy input is around 1%, which depends little on the location of the magnetopause in the model. It is also found that the energy of the cavity mode is confined in the region near the magnetopause, whereas, the energy of the toroidal mode may be distributed among a few specific L-shells. With a given size of the model magnetosphere and plasma density distri-bution, it is shown that the fundamental eigenfrequency of the cavity mode and the central locations of the FLRs do not vary noticeably with the power spectrum of the SI. It is worth noting that the spectrum of the SI affects the excitation of higher harmonics of the global cavity mode. The broader the bandwidth of the SI is, the higher harmonics of cavity mode could be excited. Meanwhile, the corresponding FLRs regions are broadened at the same time, which implies that the global cavity modes and toroidal modes can resonate on more magnetic L-shells when more harmonics of the global cavity modes appear. | YANG Biao FU SuiYan ZONG QiuGang WANG YongFu ZHOU XuZhi PU ZuYin XIE Lun | 2008 | Science China(Technological Sciences)2008，51，10： | 12 |
| 10 | A survey on numerical simulations of drag and heat reduction mechanism in supersonic/hypersonic flows显示文摘Along with the survey on experimental investigations drawing attention to the drag and heat reduction mechanism, the authors simultaneously focus on the recent advances of numerical simulations on the schemes applied to supersonic/hypersonic vehicles. The CFD study has evolved as an irreplaceable method in scheme evaluation and aircraft optimization. Similar to our previous experimental survey, the advances in drag and heat reduction schemes are reviewed by similar kinds of mechanism in this article, namely the forward-facing cavity, the opposing jet, the aerospike, the energy deposition and their combinational configurations. This review article puts an emphatic eye on the flow conditions, numerical methods, novel schemes and analytical conclusions given in the simulations. Further, the multi-objective design optimization concept has also been illustrated due to the observable advantages of using CFD over experimental method, especially those performances conducted in drag reduction and thermal protection practice, and this would possess reference value in the design of aircraft system. | Xiwan SUN Wei HUANG Min OU Ruirui ZHANG Shibin LI | 2019 | Chinese Journal of Aeronautics2019，32，4： | 12 |
| 11 | Multi-spacecraft observations of ULF waves during the recovery phase of magnetic storm on October 30, 2003显示文摘Based on observations obtained by Cluster C1, GOES 10, 12, and Polar, the global ULF wave properties are studied during the recovery phase of a very intense magnetic storm-Halloween storm (October 31, 2003, 21:00-23:00 UT). The results indicate that the ULF waves’ properties observed by different satellites, such as amplitude, period, etc. show large variations. This can be interpreted as that Field Line Resonance (FLR) might take place in the region where Cluster C1 passed. The compressional wave of the cavity mode coupled with FLR’s shear Alfven wave and fed energy to the latter, forming a large-amplitude toroidal mode. From the point of period, Cluster C1 observed the shortest period, GOES 10, 12 observed the middle, while Polar observed the longest. The wave period of toroidal mode observed by Cluster C1 kept almost unchanging when Cluster C1 passed L range from 11.7 to 5.3. Using the Squared Wavelet Coherence analysis method, we estimated that the FLR region in the dayside magnetosphere could expand to at least 4 local time widths. The toroidal mode observed by Polar was a standing wave, while the pol-oidal mode was a propagating wave, the observation results could be well ex-plained by the waveguide mode theory. Since the solarwind speed Vx was -800 km/s and the dynamic pressure varied little, we speculated that the source of the ULF wave was the Kelvin-Helmholtz instability at the magnetopause triggered by high speed solarwind. | YongFu Wang SuiYan Fu QiuGang Zong Biao Yang ZuYin Pu Lun Xie XuZhi Zhou | 2008 | Science China(Technological Sciences)2008，51，10： | 11 |
| 12 | Effect of cavity flow control on high-speed train pantograph and roof aerodynamic noise显示文摘The pantograph and its recess on the train roof are major aerodynamic noise sources on high-speed trains.Reducing this noise is particularly important because conventional noise barriers usually do not shield the pantograph.However,less attention has been paid to the pantograph recess compared with the pantograph.In this paper,the flow features and noise contribution of two types of noise reduction treatments rounded and chamfered edges are studied for a simplified high-speed train pantograph recess,which is represented as a rectangular cavity and numerically investigated at 1/10 scale.Improved delayed detached-eddy simulations are performed for the near-field turbulent flow simulation,and the Ffowcs Williams and Hawkings aeroacoustic analogy is used for far-field noise prediction.The highly unsteady flow over the cavity is significantly reduced by the cavity edge modifications,and consequently,the noise radiated from the cavity is reduced.Furthermore,effects of the rounded cavity edges on the flow and noise of the pantographs(one raised and one folded)are investigated by comparing the flow features and noise contributions from the cases with and without rounding of the cavity edges.Different train running directions are also considered.Flow analysis shows that the highly unsteady flow within the cavity is reduced by rounding the cavity edges and a slightly lower flow speed occurs around the upper parts of the raised pantograph,whereas the flow velocity in the cavity is slightly increased by the rounding.Higher pressure fluctuations occur on the folded pantograph and the lower parts of the raised pantograph,whereas weaker fluctuations are found on the panhead of the raised pantograph.This study shows that by rounding the cavity edges,a reduction in radiated noise at the side and the top receiver positions can be achieved.Noise reductions in the other directions can also be found. | Hogun Kim Zhiwei Hu David Thompson | 2020 | Railway Engineering Science2020，28，1： | 10 |
| 13 | Application of polynomial chaos on numerical simulation of stochastic cavity flow显示文摘In present paper,the mathematic background of intrusive polynomial chaos (IPC) method and coupling process with one dimension Euler equation were introduced. The IPC method was implemented for the 2D compressible stochastic Navier-Stokes equations to simulate the non-deterministic behavior of a lid driven cavity flow under the influence of uncertainties. The driven velocity and fluid viscosity were supposed respectively to be the uncertain variable which has Gaussian probability distribution. Based on the validation with benchmark results,discussions were mainly focused on the statistic properties of velocity distribution. The results indicated the effect of IPC method on the simulation of propagation of uncertainty in the flow field. For the simulated results of 2D cavity flow,influence of the driven velocity uncertainty is larger than that of viscosity. | WANG XiaoDong1,2 & KANG Shun1 1 Key Laboratory of Condition Monitoring and Control for Power Plant Equipment, Ministry of Education, School of Energy Power and Mechanical Engineering, North China Electric Power University, Beijing 102206, China 2 Department of Mechanical Engineering, Vrije Universiteit Brussel, Brussels 1050, Belgium | 2010 | Science China(Technological Sciences)2010，53，10： | 9 |
| 14 | Stepwise-Nanocavity-Assisted Transmissive Color Filter Array Microprints显示文摘Visible-light color flters using patterned nanostructures have attracted much interest due to their various advantages such as compactness,enhanced stability,and environmental friendliness compared with traditional pigment or dye-based optical flters.While most existing studies are based on planar nanostructures with lateral variation in size,shape,and arrangement,the vertical dimension of structures is a long-ignored degree of freedom for the structural colors.Herein,we demonstrate a synthetic platform for transmissive color flter array by coordinated manipulations between height-varying nanocavities and their lateral flling fractions.Te thickness variation of those nanocavities has been fully deployed as an alternative degree of freedom,yielding vivid colors with wide gamut and excellent saturation.Experimental results show that the color-rendering capability of the pixelated nanocavities can be still retained as pixels are miniaturized to 500 nm.Crosstalk between closely spaced pixels of a Bayer color flter arrangement was calculated,showing minimal crosstalk for 1μm2 square subpixels.Our work provides an approach to designing and fabricating ultracompact color flter arrays for various potential applications including stained-glass microprints,microspectrometers,and high-resolution image sensing systems. | Yasi Wang Mengjie Zheng Qifeng Ruan Yanming Zhou Yiqin Chen Peng Dai Zhengmei Yang Zihao Lin Yuxiang Long Ying Li Na Liu Cheng-Wei Qiu Joel K.W.Yang Huigao Duan | 2018 | Research2018，，1： | 8 |
| 15 | All-silicon dual-cavity fiber-optic pressure sensor with ultralow pressure-temperature cross-sensitivity and wide working temperature range显示文摘Pressure-temperature cross-sensitivity and its accompanying temperature-related stability is a nerve-wracking obstruction for pressure sensor performance in a wide temperature range.To solve this problem,we propose a novel(to the best of our knowledge)all-silicon dual-cavity optical Fabry–Perot interferometer(FPI)pressure sensor.The all-silicon structure has high intrinsic reflectivity and is able to eliminate the influence of thermal-expansion-mismatch-induced stress and chemical-reaction-induced gas generation,and therefore,in essence,enhances measurement accuracy.From the experiment results,the pressure-temperature cross-sensitivity is reduced to be∼5.96 Pa/℃,which presents the lowest pressure-temperature cross-sensitivity among the FPI pressure sensors with the capability of surviving high temperatures up to 700℃ thereby opening the way for high-precision pressure monitoring in various harsh and remote environments. | Xue Wang Junfeng Jiang Shuang Wang Kun Liu Tiegen Liu | 2021 | Photonics Research2021，9，4： | 7 |
| 16 | Cavity engineering of two-dimensional perovskites and inherent light-matter interaction显示文摘Two-dimensional(2D)perovskites are hybrid layered materials in which the inorganic lattice of an octahedron is sandwiched by organic layers.They behave as a quantum-well structure exhibiting large exciton binding energy and high emission efficiency,which is excellent for photonic applications.Hence,the cavity modulation and cavity devices of 2D perovskites are widely investigated.In this review,we summarize the rich photophysics,synthetic methods of different cavity structures,and the cavity-based applications of 2D perovskites.We highlight the strong exciton–photon coupling and photonic lasing obtained in different cavity structures.In addition,functional optoelectronic devices using cavity structures of 2D perovskites are also reviewed. | Shuai Zhang Yangguang Zhong Fan Yang Qinxuan Cao Wenna Du Jianwei Shi Xinfeng Liu | 2020 | Photonics Research2020，8，11： | 7 |
| 17 | Asymptotic solution of thermocapillary convection in two immiscible liquid layers in a shallow annular cavity显示文摘The steady laminar two-dimensional thermocapillary convection of two superposed horizontal liquid layers in a shallow annular cavity was investigated using asymptotical analysis.The liquids were supposed to be immiscible with a nondeformable interface.The cavity was heated from the outer cylindrical wall and cooled at the inner wall.Bottom and top surfaces were rigid and adiabatic.Asymptotic solutions were obtained in the core region in the limit as the aspect ratio,which was defined as the ratio of the lower layer thickness to the gap width,and trended to zero.The numerical experiments were also carried out to compare with the asymptotic solution of the steady two-dimensional thermocapillary convection.It is found that the expressions of velocity and temperature fields in the core region are valid in the limit of the small aspect ratio. | LI YouRong,WANG ShuangCheng,WU ShuangYing & SHI WanYuan College of Power Engineering,Chongqing University,Chongqing 400044,China | 2010 | Science China(Technological Sciences)2010，53，6： | 6 |
| 18 | THE SUPERPLASTICITY AND DEFORMATION MECHANISM OF ULTRALIGHT BINARY Mg-8wt%Li ALLOY显示文摘The maximum elongation-to-failure of 960% has been achieved in the Mg-8wt%Li alloy. It is shown by measurement of true stress-strain curve and microstructure observation that dynamic recrystallization takes place during superplastic deformation, which turns the banded grains into equiaxed grains. It is postulated by theoretical analysis that during superplastic deformation,continuous introduction of lattice dislocations into the phase interfaces contributes to the superplasticity in this alloy.During superplastic deformation,grain growth and cavity nucleation at α phase grain boundaries have also been observed. | F.R. Cao and J.Z. Cui(Department of Metalforming,P.O.B 317, Northeastern University, Shenyang 110006, China) | 1997 | Acta Metallurgica Sinica(English Letters)1997，10，6： | 6 |
| 19 | An association between Helicobacter pylori and upper respiratory tract disease: Fact or fiction?显示文摘Helicobacter pylori(H. pylori) is a major cause of chronic gastritis and gastric ulcers and considerable evidence supports the notion that infection with this bacterium is also associated with gastric malignancy in addition to various other conditions including pulmonary, vascular and autoimmune disorders. Gastric juice infected with H. pylori might play an important role in upper respiratory tract infection. Although direct and/or indirect mechanisms might be involved in the association between H. pylori and upper respiratory tract diseases, the etiological role of H. pylori in upper respiratory tract disorders has not yet been fully elucidated. Although various studies over the past two decades have suggested a relationship between H. pylori and upper respiratory tract diseases, the findings are inconsistent. The present overview describes the outcomes of recent investigations into the impact of H. pylori on upper respiratory tract and adjacent lesions. | Shin Kariya Mitsuhiro Okano Kazunori Nishizaki | 2014 | World Journal of Gastroenterology2014，20，6： | 6 |
| 20 | Dual-band simultaneous lasing in MOFs single crystals with Fabry-Perot microcavities显示文摘Multi-band microlasers based on single microcrystalline materials with Fabry-Perot(F-P) cavities are critically and technologically essential. Here, we demonstrate simultaneous dual-band lasing output(615 and 685 nm) in metal-organic frameworks(MOFs) and organic dyes hybrid single crystals, which support F-P resonances. Through a two-step assembly strategy, two different types of cationic pyridinium hemicyanine dye molecules can be encapsulated into the channel pores of anionic bioMOF-1-2 Me successfully. In addition, the employment of the host-guest system significantly increases the dye loading, enhances luminescent efficiency, and diminishes the aggregation-caused quenching(ACQ) effect in the resultant MOFs/dye composites.This finding not only combines the characteristic of MOFs materials with excellent luminescent properties of organic dyes, but also points out a simple and promising strategy to design multi-band microlasers based on F-P mechanism, opening a low-cost avenue for the rational design of miniaturized lasers in the future. | Hongjun Li Huajun He Jiancan Yu Yuanjing Cui Yu Yang Guodong Qian | 2019 | Science China Chemistry2019，62，8： | 6 |
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