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    题名 作者 年代 出处 被引量
1Analysis of human infectious avian influenza virus:Hemagglutinin genetic characteristics in Asia and Africa from 2004 to 2009显示文摘In the present study,we used nucleotide and protein sequences of avian influenza virus H5N1,which were obtained in Asia and Africa,analyzed HA proteins using ClustalX1.83 and MEGA4.0,and built a genetic evolutionary tree of HA nucleotides.The analysis revealed that the receptor specificity amino acid of A/HK/213/2003,A/Turkey/65596/2006 and etc mutated into QNG,which could bind withá-2,3 galactose andá-2,6 galactose.A mutation might thus take place and lead to an outbreak of human infections of avian influenza virus.The mutations of HA protein amino acids from 2004 to 2009 coincided with human infections provided by the World Health Organization,indicating a“low–high–highest–high–low”pattern.We also found out that virus strains in Asia are from different origins:strains from Southeast Asia and East Asia are of the same origin,whereas those from West Asia,South Asia and Africa descend from one ancestor.The composition of the phylogenetic tree and mutations of key site amino acids in HA proteins reflected the fact that the majority of strains are regional and long term,and virus diffusions exist between China,Laos,Malaysia,Indonesia,Azerbaijan,Turkey and Iraq.We would advise that pertinent vaccines be developed and due attention be paid to the spread of viruses between neighboring countries and the dangers of virus mutation and evolution.Jirong ZHANG Fumin LEI 2010Integrative Zoology2010,5,3:2
2Beta-blocker treatment in heart failure patients with atrial fibrillation:challenges and perspectives显示文摘Heart failure(HF)and atrial fibrillation(AF)are common conditions that share similar clinical phenotype and frequently coexist.The classification of HF in patients with preserved ejection fraction(>50%,HFpEF),midrange reduced EF(40%−49%,HFmrEF)and reduced EF(<40%,HFrEF)are crucial for optimising the therapeutic approach,as each subgroup responds differently.Betablocker constitute an important component of our pharmacological regimen for chronic HF.Betablocker administration is reccomended in patients with HF with reduced ejection fraction in stable sinus rhythm,due to improvement of symptoms,the better long termoutcome and survival.The beneficial role of betablocker use in patients with preserved EF still remain unclear,as no treatment showed a positive impact,regarding morbidity or mortality reduction.The presence of AF in HF patients increases as the disease severity evolves and is associated with a higher rate of cardiovascular morbidity and mortality.But more question is the use of betablocker in HF patients irrespective of EF and concomitant AF.There are many conflicting data and publications,regarding the beta blocker benefit in this population.Generally,it is supported an attenuation of betablockers beneficial effect in HF patients with AF.A design of more randomised trials/studies with HF patients and concomitant AF may improve our clinical approach of betablockers use and identify the patients with HF,who mostly profit from an invasive approach.Emmanouil Chourdakis Ioanna Koniari Dimitrios Velissaris Grigorios Tsigkas Nikolaos G Kounis Neriman Osman 2021Journal of Geriatric Cardiology2021,18,5:2
3Solidtinking volve在产品造型设计中的应用显示文摘针对Solidthinking Evolve软件在产品造型创意设计中的应用特点,结合化妆品包装设计制作中的应用实例,简述了Solidthinking Evolve软件以具有独创的机构树功能和快捷、便利、易学的优点,具有在产品开发领域广泛的应用前景。吕国华 2015常州信息职业技术学院学报2015,14,3:1
4Supporting the scientific advancement from pathogenic microorganisms biobank显示文摘Biobanks have emerged in the last two decades as foundational research infrastructures supporting scientific advancement.They are organized collections and providers of high-quality and research-ready biospecimens as they can authenticate,preserve,and offer independent access to biological materials,such as specimens and cultures of pathogenic microorganisms.In most cases,biospecimens will be standardized and prepared in multiple aliquots for long-term storage so that future researchers can use them as new technologies and knowledge evolve.Zisis Kozlakidis Io Hong Cheong Qiang Wei 2022Biosafety and Health2022,4,5:1
5拜登执政与中美战略竞争走向显示文摘With his four-year term of office as President of the United States,Donald Trump has caused unprecedented damage to China-US relations.Now,as Joe Biden takes power at the White House,there are widespread concerns about the following issues:How is Biden’s China policy different from Trump’s?How will the United States carry out strategic competition with China and how will China respond?And how will China-US relations evolve in the next four years?吴心伯 2021China International Studies2021,66,2:0
6Coronal sulcus-based ventral mucosal flap to help penile coverage in severe concealed penis显示文摘Introduction There are many techniques to treat congenital concealed penis(CP).Skin resurfacing is the most difficult step in severe cases.We aim to show medium-term results of coronal sulcus-based triangular ventral mucosal flap(CBVMF)as a treatment of prepubertal severe CP,a recently reported technique.We aim to determine whether results are durable and if the technique is associated with persistent mucosal redundancy or with a permanent unequal penile color pattern.Methods CP cases reconstructed with CBVMF were reviewed.Preoperative complaints,degree of motivation of the child/parent to surgery,satisfaction of parent/child with results,and surgical complications were described.Results Seven patients(6 months to 6 years old)were treated with CBVMP.Two patients showed megaprepuce and another was submitted to a limited postectomy 3 years before.One family was not fully satisfied(expected“bigger penis”),but acknowledged that the penis was now well exposed.No child talked about the problem preoperatively,but all of the boys were fully satisfied with the results of the surgery and verbalized this in the interviews.Flap edema resolved after 3 months in all but one patient.The flaps assumed the color of penile skin in the medium term.Conclusions CBMVP results were satisfactory.Serious complications did not occur.Flap edema does not persist in the medium term,and redundancy was not a problem.The color of the flap tended to evolve into a pattern similar to the penile skin.Lisieux Jesus Flavia Amaro Jamel Fernanda Gomes Talia Dias Ribeiro Samuel Dekermacher 2021World Journal of Pediatric Surgery2021,4,3:0
7Mesenchymal stem cell-based TRAIL delivery inhibits the metastatic state of clinical therapy-resistant progressive neuroblastoma显示文摘Progressive neuroblastomas(pNBs)that defy current intensive multimodal clinical therapy(IMCT)are a significant contributor to overall childhood cancer deaths[l].Neuroblastomas(NBs)that survive first-line IMCT actively evolve to acquire genetic and molecular rearrangements and display unparalleled plasticity and evolution,which causes frequent relapses in a rapidly accelerating timeline[2-4].Dinesh Babu Somasundaram Andrew Maher Sheeja Aravindan Zhongxin Yu Brian MBesch Natarajan Aravindan 2024World Journal of Pediatrics2024,20,3:0
8DWIGHT SLADE CHILDHOOD BUDDY OF BILL HICKS HEADS COMEDY TRIO显示文摘Ybu started your comedy journey with middle school friend Bill Hicks.He was obviously a legend in the game-but how did both of your styles begln and evolve in this early period?Comedy has a juvenile and in-fantUe quality to it.Snickering at your band teacher is natural for early tee ns.We just decided to make it our life's work.ANDREW CHIN 2014城市漫步(上海版、英文)2014,,1:0
9最完整的恐龙胚胎显示文摘中国科学家在蛋化石中发现了保存完好的恐龙胚胎化石标本,这个标本叫作“英良贝贝”,是一只尚未破壳的窃蛋龙宝宝。1Scientists in China have discovered a rare 66-million-year-old perfectly preserved fossil of a baby dinosaur in its egg showing similarities between theropod(兽脚类)dinosaurs and the birds they would evolve(进化)into.汤金霞 2022疯狂英语(新悦读)2022,,4:0
10REVERSE&REINCARNATION Takashi Kuribayashi and Cui Xiuwen显示文摘A pair of emerging and outspoken contemporary Asian artists share the immense space at Shanghai Gallery of Art until November 9.Takashi Kunbayashis multi-perspective work first turned heads at this years Sapporo International Art Festival and Reverse incorporates his findings sneaking onto the tsunami-stricken Fukuoka coastline.He shares the gallery space with Cui Xiuwen,the northern girt who beat China's first domestic art Lawsuit,and whose work continues to evolve,literally,taking on new dimensions in Reincarnation.ZOEY ZHA 2014城市漫步(上海版、英文)2014,,11:0
11Sexual signal conspicuity is correlated with tail autotomy in an anoline lizard显示文摘Sexual selection favors conspicuous signals that animals can use to communicate with conspecifics and/or to attract mates.However,natural and sexual selection are often in opposition,as conspicuous sexual signals can also be detected by eavesdropping predators,forcing these signals to also evolve in light of natural selection(Andersson 1994).Kelly LinWUTHRICH Derek STOCK Janelle B.TALAVERA Breanna J.PUTMAN Lindsey SWIERK 2022Current Zoology2022,68,1:0
12COLLAGE显示文摘Quentin Paquignon Since moving to Shanghai in 2005,Quentin Paquignon has watched the city's jazz scene evolve.His quartet released their debut Live in Shanghai CD last year and he will be collaborating with DJ Ben Hua ng at Unico's Valentine's Day party.We chatted with the saxophonist about his upcoming projects and to deter-mine the coolest horn.2014城市漫步(上海版、英文)2014,,2:0
13Photon Counting for a Number State Passing through a Laser Channel显示文摘We investigate the photon counting for a pure number state passing through a laser channel.It is found that the pure number state evolves in the laser channel into a mixed state:the number state|m>王长春 袁洪春 范洪义 2012Chinese Physics Letters2012,29,11:0
14Microstructure design using graphs显示文摘Thin films with tailored microstructures are an emerging class of materials with applications such as battery electrodes,organic electronics,and biosensors.Such thin film devices typically exhibit a multi-phase microstructure that is confined,and show large anisotropy.Current approaches to microstructure design focus on optimizing bulk properties,by tuning features that are statistically averaged over a representative volume.Here,we report a tool for morphogenesis posed as a graph-based optimization problem that evolves microstructures recognizing confinement and anisotropy constraints.We illustrate the approach by designing optimized morphologies for photovoltaic applications,and evolve an initial morphology into an optimized morphology exhibiting substantially improved short circuit current(68% improvement over a conventional bulk-heterojunction morphology).We show optimized morphologies across a range of thicknesses exhibiting self-similar behavior.Results suggest that thicker films(250 nm)can be used to harvest more incident energy.Our graph based morphogenesis is broadly applicable to microstructure-sensitive design of batteries,biosensors and related applications.Pengfei Du Adrian Zebrowski Jaroslaw Zola Baskar Ganapathysubramanian Olga Wodo 2018npj Computational Materials2018,,1:0
15EPICES&FOIE GRAS French-owned bistro near Nanjing Dong Lu显示文摘No prizes for guessing what this place specializes in.Epices&Foie Gras'menu revolves around...foie gras,devised in many ways,both as standalone dishes and worked into French bistro classics.The fattened liver of duck and goose appears in tlie majority of menus at Western restaurants in Shanghai,but Epices takes it a little step fUrther with some interesting combinations tliat warrant a visit.BEHY RICHARDSON 2014城市漫步(上海版、英文)2014,,12:0
16The molecular evolution of spermatogenesis across mammals显示文摘The testis produces gametes through spermatogenesis and evolves rapidly at both the morphological and molecular level in mammals1-6,probably owing to the evolutionary pressure on males to be reproductively successful7.However,the molecular evolution of individual spermatogenic cell types across mammals remains largely uncharacterized.Florent Murat 2022四川生理科学杂志2022,44,12:0
17Did ZIKV evolve to be more dangerous? A new clue towards neurovirulence显示文摘Before 2015,Zika virus(ZIKV)was a little-known flavivirus that caused sporadic symptomatic infections in humans(under 20 reported cases,but likely manymore unreported asymptomatic cases)in the decades following its discovery during 1947 in Africa.Infections with ZIKV result in a mild acuteGary Wong George F.Gao 2018National Science Review2018,5,2:0
18What is the Future Road for Mineral Exploration in the 21st Century?显示文摘The future trends for mineral exploration study should depend on the demands from our society and industry,which have clearly changed in the past decade and will continuously evolve in the future.In general,three major challenges on mineral exploration have been raised for all economic geologists,including:(1)deep exploration;(2)intelligent exploration and;(3)green exploration(i.e.,“DIG”exploration).Huayong Chen Junling Zhang 2022Journal of Earth Science2022,33,5:0
19跟踪导练(三)(英文)显示文摘选词填空从下列方框里10个单词中选择8个适当单词的正确形式填入下列各句中,使其句意完整。每个单词只使用一次。sceptical volcano adapt unlikely claw extinct generous emperor evolve border1.From the result we can know that the children have____to the changes quickly.2.From their work,we have learned how our planet____.3.His illness is so serious that he is____to live.2015时代英语(高一版)2015,0,2:0
20Role of fullerenols derivative 3HFWC in the treatment of Alzheimer's disease显示文摘Fullerenes:The extensive development of nanoscience that has marked this century continues to evolve,producing new materials,structures,and devices for the treatments of diverse pathologies.Fullerenes are a family of nanoparticles with great applicative promise due to their small size(approximately 1 nm in diameter),structure,and capacity to cross biological barriers.Sanja Ivkovic Djuro Koruga 2024Neural Regeneration Research2024,19,8:0
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