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| 1 | Abrupt Holocene changes of the Asian monsoon at millen-nial-and centennial-scales: Evidence from lake sediment document in Minqin Basin, NW China显示文摘Considerable research is now focusing on abrupt Holocene changes at millennial- and centennial-scales all over the world. This study shows that the changes in theHolocene summer monsoon can be divided into two main periods, based on climatic proxy records of lake sediments from the Sanjiaocheng section located at the NW boundary of the summer monsoon, Gansu Province. The early and middle Holocene was humid with stronger summer monsoon, while the late Holocene is dry with weak summer monsoon. Detailed results also show a series of millennial- and centennial-scale changes in the intensity of the summer monsoon, with a periodicity of 1600 years during the whole Holocene, and with a periodicity of 800 years during the early Holocene. Ten dry events during the Holocene are associated with the weakening of the summer monsoon. These rapid climatic changes may be representative of a global climatic change pattern during the Holocene. | CHEN Fahu ZHU Yan LI Jijun SHI Qi JIN Liya B.Wunemann | 2001 | Chinese Science Bulletin2001，46，23： | 61 |
| 2 | TME术前短程放疗后化疗对比术前放化疗联合术后辅助化疗治疗局部晚期直肠癌(RAPIDO研究)—一项随机、开放的Ⅲ期临床试验显示文摘背景:全身复发仍然是局部晚期直肠癌患者需要面临的难题。该研究是采用短程放疗后行化疗和延迟手术对比术前诱导治疗后直接手术疗效的临床试验(the Rectal cancer And Preoperative Induction therapy followed by Dedicated Operation,RAPIDO),旨在不影响局部控制效果的前提下减少远处转移。方法:在这项多中心、随机、开放的Ⅲ期试验中,参与者来自于荷兰、瑞典、西班牙、斯洛文尼亚、丹麦、挪威和美国的共54个医学中心。纳入患者年龄在18岁及以上,ECOG评分为0~1分,且为经活检确诊局部晚期原发直肠腺癌的初诊患者,盆腔MRI评估为高危(至少符合一项标准:cT4a或cT4b,壁外血管侵犯,cN2,直肠系膜筋膜受累,或侧方淋巴结增大)。患者具备化疗适应证,并可在随机分组前5周内完成分期评估。 | 李来元 张维胜 BAHADOER R R DIJKSTRA E A VAN ETTEN B | 2021 | 结直肠肛门外科2021，27，1： | 72 |
| 3 | 迷走神经刺激调节睡眠的机制研究进展显示文摘睡眠是机体对外界意识中断和反应性降低的生理现象,为独立的生物节律,由非快速眼动睡眠期(non—rapid eye movement,NREM)和快速眼动睡眠期(rapid eye moovement,REM)交替组成,对机体的新陈代谢、精力恢复、学习记忆、生长发育等有重要作用。随着社会生活方式的转变,失眠的发病率逐渐升高,2015年全国睡眠指数报告显示,中国人失眠率31.2%,高于世界27%的平均水平。短期失眠可疲乏嗜睡、烦躁头晕、工作效率低下,长期缺乏睡眠可引起情绪不稳、免疫力下降,促心脑血管病、糖尿病的发生。 | 王娴 刘爱华 | 2015 | 中风与神经疾病杂志2015，32，12： | 42 |
| 4 | 阿尔金淡水泉早古生代泥质高压麻粒岩及其P-T演化轨迹显示文摘南阿尔金构造带淡水泉一带出露的含石榴石蓝晶石黑云母片麻岩是一套典型的泥质高压麻粒岩,其峰期特征矿物组合为石榴子石+蓝晶石+钾长石+金红石+石英。根据矿物内部一致性热力学数据和Thermocalc 3.23程序计算,确定其峰期变质温压条件为T>850℃和P>11kbar。结合岩相学研究和P-T视剖面图计算,可识别出该岩石经历了4个阶段的变质演化,构成了一个早期快速等温降压,后期近等压降温的顺时针型的退变质P-T演化轨迹,为与陆壳俯冲碰撞有关的高压变质事件的产物。该岩石锆石阴极发光图像显示其内部具有明显的核-边结构,核部为残留的原岩碎屑锆石,边部则表现为面状或扇状生长的变质锆石的特征。微区原位LA-ICP-Ms微量元素分析表明,核部测点的重稀土含量较高,对应Th/U接近于0.4,具有岩浆锆石的特征;边部测点的重稀土相对亏损,重稀土配分曲线平坦,对应Th/U比值均小于0.1,显示与石榴子石平衡共生的变质锆石特征。LA-ICP-MS微区定年获得其变质年龄为486±5Ma,该年龄值与阿尔金江尕勒萨依和英格利萨依两地超高压变质岩石的变质年龄相近,进一步证明沿阿尔金构造带南缘断续存在一条早古生代的高压-超高压变质岩带。另外,本次研究在获得该泥质高压麻粒岩峰期变质时代的同时,还获得该岩石原岩的形成时代上限值约为719Ma,从而限定阿尔金构造带南缘阿尔金群的形成时代可能不属古元古代,而应属新元古代。 | 曹玉亭 刘良 王超 陈丹玲 张安达 | 2009 | 岩石学报2009，25，9： | 35 |
| 5 | CdTe/ZnSe核壳量子点免疫层析试纸条检测克伦特罗的研究显示文摘采用巯基丁二酸作为表面修饰剂,水相法合成水溶性的CdTe/ZnSe核壳量子点,然后在N-羟基琥珀酰亚胺(NHS)的作用下,将CdTe/ZnSe核壳量子点与抗克伦特罗多克隆抗体(Anti-CLE pAb)连接。通过凝胶电泳和斑点杂交实验,验证CdTe/ZnSe核壳量子点与Anti-CLE pAb连接成功,并且CdTe/ZnSe-Anti-CLE pAb偶联物能识别克伦特罗-BSA抗原(CLE-BSA)。光谱分析表明,量子点与抗体连接后荧光增强,荧光峰位从628nm红移至635nm。将合成的CdTe/ZnSe-Anti-CLE pAb偶联物作为指示克伦特罗(CLE)分子的荧光标记物,制备出一种用于检测CLE的免疫层析试纸条,其最低检测量可达1μg/L。与ELISA法的对比实验表明,此试纸条能应用于CLE残留的快速检测。 | 胡华军 付涛 张明洲 洪治 陈宗伦 刘军 | 2010 | 分析化学2010，38，12： | 32 |
| 6 | Management Recommendations on Sleep Disturbance o Patients with Parkinson's Disease显示文摘INTRODUCTION Sleep disturbance is one of the most common nonmotor symptoms in Parkinson's disease (PD).Sleep disturbance affects 40-98% of PD patients in the world. In China, the prevalence of PD patients with sleep disturbance ranges from 47.66% to 89.10%. Sleep disturbance usually has adverse impact on the quality of life of PD patients. Apossible pathogenesis of PD with sleep disturbance include thalamocortical pathway degeneration and changes of neurotransmitter systems. The etiology of sleep disturbance is multifactorial,involving degeneration of areas regulating sleep,sleep structure affected by drugs,sleep disturbance induced by drug,and sleep fragmentation by multiple factors. | Chun-Feng Liu Tao Wang Shu-Qin Zhan De-Qin Geng Jian Wang Jun Liu Hui-Fang Shang Li-Juan Wang Piu Chan Hai-Bo Chen Sheng-Di Chen Yu-Ping Wang Zhong-Xin Zhao K Ray Chaudhuri | 2018 | Chinese Medical Journal2018，，24： | 26 |
| 7 | Introduction to the overall physics design of CSNS accelerators显示文摘The China Spallation Neutron Source (CSNS) is an accelerator-based facility. The accelerator of CSNS consists of a low energy linac, a Rapid Cycling Synchrotron (RCS) and two beam transport lines. The overall physics design of CSNS accelerator is described, including the design principle, the choice of the main parameters and design of each part of accelerators. The key problems of the physics design, such as beam loss and control, are also discussed. The interface between the different parts of accelerator, as well as between accelerator and target, are introduced. | 王生 方守贤 傅世年 刘渭滨 欧阳华甫 秦庆 唐靖宇 韦杰 | 2009 | Chinese Physics C2009，33，S2： | 20 |
| 8 | Rapid Prototyping and Manufacturing Technology:Principle, Representative Technics, Applications, and Development Trends显示文摘The rapid prototyping and manufacturing technology (RPM), is an integration of many different disciplines. It is based on an advanced dispersed-accumulated forming principle and originated from 1980s. It generates an entity by first forming a series of layers according to the dispersed section information of the digital model, and then piling the formed layers sequentially together. It is capable of forming parts with complicated structures and non-homogeneous materials. Traditional RPM techniques are mainly used as prototypes in product invention process, such as stereolithography, three-dimensional printing, laminated object manufacturing, and fused deposition modeling. Later, with the progress of material and enabling technology, many new RPM techniques emerged out and have been already applied in the fields such as rapid tooling/moulding, direct formed usable part, nano-/micro-RPM, and biomanufacturing. This high flexible digital manufacturing method has a likely ability to become an almighty forming technology. | 颜永年 李生杰 张人佶 林峰 吴任东 卢清萍 熊卓 王小红 | 2009 | Tsinghua Science and Technology2009，14，S1： | 17 |
| 9 | Effects of temperature on the tribological behavior of Al0.25CoCrFeNi high-entropy alloy显示文摘The tribological behavior of Al0.25 CoCrFeNi high-entropy alloy(HEA) sliding against Si3N4 ball was investigated from room temperature to 600°. The microstructure of the alloys was characterized by simple FCC phase with 260 HV. Below 300°, with increasing temperature, the wear rate increased due to high temperature softening. The wear rate remained stabilized above 300°due to the anti-wear effect of the oxidation film on the contact interface. The dominant wear mechanism of HEA changed from abrasive wear at room temperature to delamination wear at 200°, then delamination wear and oxidative wear at 300°and became oxidative above 300°. Moreover, the adhesive wear existed concomitantly below 300°. | L.M.Du L.W.Lan S.Zhu H.J.Yang X.H.Shi P.K.Liaw J.W.Qiao | 2019 | Journal of Materials Science & Technology2019，35，5： | 17 |
| 10 | Expressions of ICAM-1 and its mRNA in sera and tissues of patients with hepatocellular carcinoma显示文摘INTRODUCTIONThe increased expression of ICAM-1 on a widerange of cells and in the sera of patients withmalignancies, chronic liver diseases andinflammation diseases has been described since thelate 1980s[1-22]. Recently rapid progress in studieson expression of ICAM-1 in patients withhepatocellular carcinoma ( HCC ) have beenachieved, including clinical and experimentalresearches[23-31]. | Jing Xu1 Ming Hui Mei1 Si En Zeng2 Qing Fen Shi3 Yong Ming Liu4 Li Ling Qin3 1Department of Hepatobiliary Surgery2Department of Pathology3Institute of Hepatobiliary Surgery4Department of Biochemistry, Guilin 541001, Guangxi Province, China | 2001 | World Journal of Gastroenterology2001，7，1： | 14 |
| 11 | Development of a welding system for 3D steel rapid prototyping process显示文摘Metal device rapid prototyping with welding is one of the research interests at present. A controlled inertial droplet transfer MAG welding (CIDTMAGW) process was developed for the 3D steel device rapid prototyping with metal deposition. In this process, by using a special designed wire feeder, a controlled inertia is imposed on the droplet formed on the wire tip and combines with the arc force to make it detached. Thus, according to the requirements of rapid prototyping, the arc heat and the droplet detaching force can be separately controlled to attain a stable and satisfactory metal deposition process. A CIDTMAGW system and a testing manipulator for the 3D steel device rapid prototyping are presented. The required software is completed as well. The experiments proved that the geometric formation of the rapid prototyping device with welding deposition is well agreed the data of the device CAD modeling. The surface of the deposited device is comparatively smooth. | 杨世彦 韩明武 王其隆 | 2001 | China Welding2001，10，1： | 14 |
| 12 | Rapid mitogen-activated protein kinase activation by transforming growth factor α in wounded rat intestinal epithelial cells显示文摘RapidmitogenactivatedproteinkinaseactivationbytransforminggrowthfactorαinwoundedratintestinalepithelialcelsMichaelGkee,Michi... | Michael Gke, Michiyuki Kanai, Kathryn Lynch Devaney, and Daniel K. Podolsky Gastrointestinal Unit, Department of Medicine, and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, Massa | 1998 | World Journal of Gastroenterology1998，4，3： | 14 |
| 13 | CLIMATOLOGICAL FEATURES OF RAPIDLY INTENSIFYING (RI) TROPICAL CYCLONES IN NW PACIFIC WEST OF 135°E^1显示文摘Tropical cyclones which rapidly intensify (ΔV≥ 20 m/s in 24 h)in the Northwest Pacific Ocean west of 135°E could have adverse influence on oceanic and coastal economic activities in China, 71% of which land in China. Rapid intensification is mostly seen east and northeast of the Luzon Island. It is much correlated with sea surface temperature(≥28℃)and upper air conditions, such as enhanced subtropical high, onset of Southwest monsoon surge, invasion of modest cold air, and Tropical Upper Tropospheric Trough(TUTT) etc. Abovementioned processes enhance inflows in the low level and deep convection in the area of inner core. Statistics of satellite pixels have confirmed that rapidly intensifying tropical cyclones are marked by a sharp increase in the inner core convection and stable or slowly-increasing deep convection in outer region. Non-rapidly intensifying tropical cyclones have only constant or decreased deep convection in inner core and outer region. The sharp increasing of deep convection in the inner core and the rapid warming in its upper level is a forewarning of rapid intensification of tropical cyclones. | 阎俊岳 张秀芝 李江龙 | 1998 | Journal of Tropical Meteorology1998，4，1： | 11 |
| 14 | INTERACTION OF PRECIPITATION AND RECRYSTALLIZATION IN RAPIDLY SOLIDIFIED Cu-Cr-Zr-Mg ALLOY显示文摘In this paper; the recrystallization process during aging for a rapidly solidified Cu-Cr-Zr-Mg alloy has been investigated. It is found that the discotinuous crystallization process has been partially retarded by the ultra-fine and dispersed precipitation upon aging after deformation. Thus, a phenomenon of combined in situ and discontinuous recrystallization has been observed in the rapidly solidified Cu-Cr-Zr-Mg alloy.On the nucleation and growth of recrystallization, the precipitated phases are coarscned and dissolved in the front of grain boundaries following a re-precipitation in the recrystallization area,which results in the much more dispersed precipitates. | Liu, P. Kang, B.X. Cao, X.G. Huang, J.L. Yin, B. Gu, H.C. | 1999 | Acta Metallurgica Sinica(English Letters)1999，12，3： | 11 |
| 15 | An overview of design for CSNS/RCS and beam transport显示文摘The China Spallation Neutron Source (CSNS) is the first accelerator-based pulsed neutron source in China. Its accelerators are made up of an 80 MeV H- linac, a Rapid Cycling Synchrotron (RCS) and two beam transport lines. RCS accumulates and accelerates protons to the design energy of 1.6 GeV, and extracts high energy beam to strike the target. The overview of RCS is presented, and the key problems of the physics design are discussed. The two beam transport lines, from linac to RCS and from RCS to the target, are also introduced. | WANG Sheng AN YuWen FANG ShouXian HUANG Nan LIU WeiBin LIU YuDong QIN Qing QIU Jing WANG Na XU Gang XU ShouYan YU ChengHui | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，S2： | 11 |
| 16 | Slice Data Based Support Generation Algorithm for Fused Deposition Modeling显示文摘This paper presents a robust algorithm to generate support for fused deposition modeling (FDM). Since many flaws appear in most stereo lithography (STL) models, this algorithm utilizes slice data as input. A top-down approach was used to calculate the support slice layer by layer. The generation algorithm was described in detail including the slice grouping, oriental bounding box (OBB) calculation, offsetting, and Boolean operations. Several cases are given to validate the efficiency and robustness of the procedure. The algorithm provides necessary support not only for hanging surface but also for hanging vertexes and edges with O(n) time complexity, where n is the number of layers. The algorithm fully utilizes the parts' self-support ability and reduces support volume to the maximum extent. This slice data based algorithm has the same efficiency as the STL based algorithm but is more stable, which significantly enhances the robustness of the support generation process. | 黄小毛 叶春生 莫健华 刘海涛 | 2009 | Tsinghua Science and Technology2009，14，S1： | 10 |
| 17 | 计算流体力学在船舶线型优化中的应用显示文摘以某船舶的计算流体力学(简称CFD)阻力性能计算为例,结合传统的实验流体力学(简称EFD)模型试验计算结果,比较分析了该船原型和改型的性能差异,总结和归纳了CFD在船型优化方面的优势。 | 陈伟民 陈霞萍 | 2007 | 上海船舶运输科学研究所学报2007，30，1： | 9 |
| 18 | 北大别超高压榴辉岩的快速折返与缓慢冷却过程显示文摘岩石学研究表明,北大别超高压榴辉岩经过了超高压和高压榴辉岩相变质作用以及麻粒岩相叠加和角闪岩相退变质作用。其中,高压麻粒岩相和角闪岩相变质阶段形成的后成合晶以及石榴子石和单斜辉石等矿物中成分分带的存在,证明该区榴辉岩经历了一个快速折返过程;而不同变质阶段的温度、压力和形成时代,却反映该区榴辉岩在峰期超高压变质作用之后又经历了一个缓慢冷却过程。超高压岩石折返期间的缓慢冷却过程也许正是北大别长期难以发现柯石英和有关超高压证据的重要原因。因此,本文为大别山不同超高压岩片的差异折返模型的建立提供了新的证据。 | 刘贻灿 古晓锋 李曙光 | 2009 | 岩石学报2009，25，9： | 8 |
| 19 | Containerless rapid solidification of undercoolecl Cu-Co peritectic alloys显示文摘Droplets of Co-16%Cu and Co-71.6%Cu peritectic alloys were solidified during container-less processing in a 3-m drop tube. The microstructures of Co-16%Cu alloy droplets were characterized by dendritic or equiaxed α-Co phase with a small amount of Cu-rich solid solution distributed on α-Co phase boundaries. Two thresholds of droplet diameter were observed for Co-16%Cu alloy at which 'equiaxed-dendritic-equiaxed' morphological transitions occur to primary α-Co phase. This conspicuous refinement of primary α-Co grains results from the fragmentation of α-Co dendrites caused by re-calescence effect. For Co-71.6% Cu alloy, the primary a-Co phase forms as coarse columnar dendrites in large droplets and equiaxed dendrites in small droplets. Theoretical calculations indicate that Marangoni migration contributes more to the growth of disperse Co-rich spheres by stimulating collision and coalescence than Stokes motion caused by the residual gravity in the falling Co-71.6%Cu alloy droplets. | 曹崇德 王楠 魏炳波 | 2000 | Science China Mathematics2000，43，12： | 8 |
| 20 | Rapid Growth of Halide Perovskite Single Crystals:From Methods to Optimization Control显示文摘Metal halide perovskites are emerging as new generation optoelectronic materials due to their high carrier mobility, long carrier diffusion length and large light absorption coefficient, which have broad applications in solar cell, light-emitting diode, laser, photodetector and transistors. Perovskite single crystal is an ideal platform for discerning the intrinsic properties of these materials. In some cases, perovskite single crystals are better candidates to gain high performance optoelectronics. However, the growth of perovskite single crystals is time and cost consuming, which has an obvious disadvantage for device exploration. Therefore, fast growth technique is highly desirable in not only promoting the use of perovskites in commercial applications but also facilitating deep physical investigation of the materials. In this review, we summarize thoroughly the development of fast growth of the halide perovskites single crystal. Specifically, we highlight the progress of rapid growth techniques with emphasis on the optimization control. | Yu-Ling Wang Shuai Chang Xiao-Mei Chen Yan-Dong Ren Li-Fu Shi Yong-Hao Liu Hai-Zheng Zhong | 2019 | Chinese Journal of Chemistry2019，37，6： | 8 |
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