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Studies on mechanism of Sialy Lewis-X antigen in liver metastases of human colorectal carcinoma

查看全文 作  者:Xiao Wei Li~1 Yan Qing Ding~1 Jun Jie Cai~1 Shao Qing Yang~2 Lian Bing An~3 Dong Fang Qiao~3 ~1Department of Pathology,Nanfang Hospital of the First Military Medical University,Guangzhou 510515,Guangdong Province,China ~2The Northern Hospital of PLA,Shenyang 110015,Liaoning Province,China ~3Department of Electronmicroscopy,First Military Medical University,Guangzhou 510515,Gangdong Province,ChinaDr.Xiao Wei Li graduated from the First Military Medical University with a MM degree in 1999.Physician in Charge of pathology,having 6 papers published. 高影响力作者 出  处:《World Journal of Gastroenterology》索引2001年第7卷第3期,共6页高影响力期刊 基  金:Supported by the Key Proqrams of PLA,No.96Z028 摘  要:INTRODUCTIONSialyl Lewis-X antigen ,correlated with carcinoma, is a group of carbohydrate antigen containing oligosaccharide expressed of embryonic tisue and glycoproteins on cell surface of embryonic tissue[1].The SLeX antigen located on cell surface is synthesized principally by two enzymes ,al ,3fucosyltransfrease and a2, 3sialyctransferase.In adults ,SLeX antigen is expressed principally on the surfaces of granulocytic cells and some tumor cells . 关 键 词:antigen, CD15S colorectal neoplasms/pathology liver neoplasms/secondary NEOPLASMS metastasis tumor cells, cultured E-SELECTIN
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