维普中文期刊产品整合服务

Furazolidone,amoxicillin,bismuth and rabeprazole quadruple rescue therapy for the eradication of Helicobacter pylori

查看全文 作　　者：Hong Cheng Fu-Lian [1]Hu 高影响力作者 机构地区：[1]Department of Gastroenterology,Peking University First Hospital, Beijing 100034, China高影响力机构 出　　处：《World Journal of Gastroenterology》索引2009年第15卷第7期,共5页高影响力期刊 摘　　要：AIM:To compare the efficacy and side effect profiles of three furazolidone and amoxicillin-based quadruple rescue therapies for the eradication of Helicobacter pylori(H pylori).METHODS:Patients who failed in the H pylori eradication therapy for at least one course were randomly allocated into three groups.Group A received rebaprazole 10 mg + amoxicillin 1 g + furazolidone 100 mg,and bismuth subcitrate 220 mg,twice daily for 1 wk;group B received the same regimen of group A but for 2 wk;and group C received the same regimen of group B,but furazolidone was replaced by furazolidone 100 mg three times daily.To record the side effect profiles at the end of the treatment,H pylori eradication was assessed with 13C-urea breath test 4 wk after therapy.RESULTS:Sixty patients were enrolled including 28 males,and 20 patients in each group.The average age of the patients was 49.2 years,ranging from 18 to 84 years.H pylori eradication rates with per-protocol analysis were 82%,89% and 90% in the three groups,respectively.Side effects were found in 11 patients,including mild dizziness,nausea,diarrhea and increased bowel movement.None of the 11 patients needed treatment for their side effects.CONCLUSION:One-or two-week furazolidone and amoxicillin-based quadruple rescue therapy with a low dose furazolidone(100 mg bid) for the eradication of H pylori is effective.Extending the antibiotic course to 14 d could improve the eradication rates. 关 键 词：根除幽门螺杆菌 呋喃唑酮 根除治疗 次枸橼酸铋 阿莫西林 雷贝拉唑 救援 HPYLORI
相关文献

参考文献(26)

引证文献(27)

耦合文献(85)

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费